EFI - Enzyme Similarity Tool

Pfam Families

These data are sourced from the UniProt and EMBL-EBI InterPro databases.

Clan ID Short Name Size UniRef90 Size UniRef50 Size Pfam ID Short Name Size UniRef90 Size UniRef50 Size
CL0001 EGF 157,263 78,369 31,821 PF00008 EGF 44,816 23,609 9,792
PF00053 Laminin_EGF 21,886 11,458 4,003
PF00084 Sushi 29,762 15,380 6,852
PF00594 Gla 4,623 2,144 523
PF01414 DSL 3,735 1,653 638
PF04863 EGF_alliinase 486 256 87
PF06247 Plasmod_Pvs28 411 61 24
PF07645 EGF_CA 47,793 24,460 9,704
PF07974 EGF_2 11,060 5,015 2,352
PF09014 Sushi_2 549 286 71
PF09064 Tme5_EGF_like 289 215 91
PF09289 FOLN 2,097 667 140
PF09443 CFC 441 252 101
PF12661 hEGF 16,290 8,139 3,267
PF12662 cEGF 12,705 6,143 2,012
PF12946 EGF_MSP1_1 2,398 194 66
PF12947 EGF_3 10,331 4,508 2,034
PF14670 FXa_inhibition 19,841 9,044 2,877
PF18193 Fibrillin_U_N 981 458 62
PF18372 I-EGF_1 3,829 1,239 281
PF18720 EGF_Tenascin 2,629 1,229 329
CL0003 SAM 81,175 34,682 10,653 PF00536 SAM_1 43,455 19,270 6,025
PF01698 SAM_LFY 1,551 276 55
PF02198 SAM_PNT 6,271 2,249 806
PF04904 NCD1 1,051 368 142
PF07647 SAM_2 28,772 12,641 3,726
PF09235 SAM_Ste50p 60 39 19
PF09597 IGR 1,336 757 253
PF13543 SAM_KSR1 1,015 503 146
PF18016 SAM_3 3,818 1,519 403
PF18017 SAM_4 841 446 204
PF18255 SAM_DrpA 756 92 14
PF18609 SAM_Exu 172 114 50
CL0004 Concanavalin 396,438 216,471 77,541 PF00054 Laminin_G_1 7,566 4,179 1,506
PF00139 Lectin_legB 10,905 6,385 2,342
PF00262 Calreticulin 6,761 3,064 787
PF00337 Gal-bind_lectin 9,840 5,163 1,947
PF00354 Pentaxin 5,990 3,261 1,270
PF00426 VP4_haemagglut 7,809 466 45
PF00457 Glyco_hydro_11 4,508 2,311 519
PF00622 SPRY 48,796 25,559 8,125
PF00629 MAM 14,140 7,170 3,169
PF00722 Glyco_hydro_16 44,038 24,907 8,015
PF00840 Glyco_hydro_7 7,666 2,401 382
PF01670 Glyco_hydro_12 4,395 2,265 680
PF01828 Peptidase_A4 2,531 1,590 662
PF02210 Laminin_G_2 27,242 13,399 4,294
PF02973 Sialidase 719 239 100
PF03388 Lectin_leg-like 5,039 2,423 794
PF03935 SKN1 3,435 2,193 615
PF05592 Bac_rhamnosid 12,146 7,463 1,877
PF05735 TSP_C 3,878 1,276 294
PF06439 DUF1080 29,303 20,010 5,176
PF06955 XET_C 6,859 3,026 549
PF07081 DUF1349 7,758 3,478 774
PF07177 Neuralized 3,007 1,402 560
PF07622 DUF1583 169 131 89
PF07675 Cleaved_Adhesin 1,584 1,250 825
PF07953 Toxin_R_bind_N 343 58 34
PF08244 Glyco_hydro_32C 22,955 10,070 2,373
PF08787 Alginate_lyase2 4,686 2,180 607
PF08978 Reoviridae_Vp9 39 15 11
PF09101 Exotox-A_bind 231 48 21
PF09206 ArabFuran-catal 1,740 911 194
PF09224 DUF1961 655 408 123
PF09264 Sial-lect-inser 87 28 18
PF10287 DUF2401 964 578 174
PF11476 TgMIC1 18 4 4
PF11958 DUF3472 1,803 1,005 341
PF12248 Methyltransf_FA 1,602 983 483
PF13385 Laminin_G_3 60,021 42,560 24,542
PF13765 PRY 26,466 15,165 4,300
PF14099 Polysacc_lyase 2,798 1,865 981
PF15493 YrpD 147 49 31
PF16346 DUF4975 542 247 64
PF16451 bCoV_S1_N 1,840 123 34
PF17689 Arabino_trans_N 2,989 1,048 142
PF17851 GH43_C2 18,086 9,100 1,618
PF17974 GalBD_like 1,341 473 153
PF18239 HA1 7 4 3
PF18271 GH131_N 1,578 934 237
PF18483 Bact_lectin 3,204 2,015 1,283
CL0005 Kazal 23,543 11,623 4,942 PF00050 Kazal_1 7,537 4,534 2,395
PF07648 Kazal_2 17,297 7,898 3,165
PF18434 Kazal_3 599 211 34
CL0006 C1 68,862 32,673 9,885 PF00130 C1_1 39,772 17,448 4,210
PF00569 ZZ 20,467 10,104 3,571
PF03107 C1_2 6,770 4,269 1,936
PF07975 C1_4 1,855 860 177
CL0007 KH 248,421 88,317 15,680 PF00013 KH_1 98,184 37,036 8,193
PF04025 DUF370 6,247 2,435 422
PF07650 KH_2 72,478 22,079 2,336
PF09869 DUF2096 179 136 43
PF13083 KH_4 24,625 9,642 1,805
PF13184 KH_5 35,433 11,328 1,393
PF14611 SLS 863 535 308
PF14955 MRP-S24 673 398 123
PF15985 KH_6 4,720 2,423 689
PF16005 MOEP19 493 249 127
PF17214 KH_7 2,022 861 123
PF17903 KH_8 3,137 1,510 303
PF17904 KH_9 2,506 767 154
PF17905 KH_10 59 39 23
CL0009 ENTH_VHS 34,009 15,626 4,176 PF00790 VHS 13,725 6,162 1,563
PF01417 ENTH 8,441 4,128 1,261
PF07651 ANTH 11,848 5,346 1,359
CL0010 SH3 381,749 148,952 44,594 PF00018 SH3_1 88,514 38,894 11,266
PF00552 IN_DBD_C 58,222 5,013 726
PF01302 CAP_GLY 15,590 8,074 2,944
PF02736 Myosin_N 11,997 5,355 907
PF03217 SlpA 3,332 1,535 845
PF03831 YjdM 15,606 5,119 228
PF06347 SH3_4 7,770 4,690 1,745
PF06372 Gemin6 506 288 140
PF07563 DUF1541 1,557 762 122
PF07653 SH3_2 31,558 14,110 4,433
PF07866 DUF1653 7,080 3,129 669
PF08239 SH3_3 43,517 22,520 11,332
PF08460 SH3_5 2,681 797 397
PF08810 KapB 1,231 448 49
PF11095 Gemin7 502 329 187
PF11302 DUF3104 181 132 63
PF11607 DUF3247 327 148 39
PF11623 NdhS 710 300 59
PF12208 DUF3601 174 72 47
PF12913 SH3_6 3,459 1,045 375
PF13457 GW 3,235 1,144 628
PF14603 hSH3 935 478 157
PF14604 SH3_9 48,361 22,019 6,834
PF14627 DUF4453 81 62 40
PF15505 DUF4648 175 66 15
PF17384 DUF150_C 25,210 9,946 1,934
PF17902 SH3_10 5,199 2,010 510
PF18103 SH3_11 144 17 3
PF18129 SH3_12 2,062 1,114 388
PF18335 SH3_13 10,855 4,335 927
PF18343 SH3_14 222 17 4
PF18346 SH3_15 1,997 807 268
PF18348 SH3_16 7,418 4,305 897
PF18350 SH3_17 45 11 1
PF18354 SH3_18 48 24 6
PF18597 SH3_19 570 343 51
PF18697 MLVIN_C 1,333 756 456
CL0011 Ig 343,113 172,015 63,032 PF00047 ig 22,988 10,497 4,900
PF01537 Herpes_glycop_D 693 126 73
PF01688 Herpes_gI 430 57 35
PF02124 Marek_A 740 78 38
PF02440 Adeno_E3_CR1 348 66 25
PF02480 Herpes_gE 940 167 114
PF02960 K1 1,211 93 10
PF03921 ICAM_N 1,177 627 280
PF05790 C2-set 680 224 77
PF07654 C1-set 57,456 17,070 4,691
PF07679 I-set 111,150 53,549 21,089
PF07686 V-set 108,698 66,304 20,527
PF08204 V-set_CD47 622 205 106
PF08205 C2-set_2 19,848 10,003 4,325
PF09085 Adhes-Ig_like 194 85 24
PF09191 CD4-extracel 264 89 24
PF09291 DUF1968 175 116 37
PF10430 Ig_Tie2_1 337 100 20
PF11465 Receptor_2B4 401 243 134
PF13895 Ig_2 24,686 13,586 6,574
PF13927 Ig_3 86,469 43,706 17,625
PF15028 PTCRA 120 75 28
PF15910 V-set_2 515 214 70
PF16680 Ig_4 543 336 114
PF16681 Ig_5 317 199 71
PF16706 Izumo-Ig 231 114 53
PF16758 UL141 160 12 6
PF17736 Ig_C17orf99 819 372 137
PF17737 Ig_C19orf38 149 100 51
PF18452 Ig_6 2,059 822 225
PF18589 ObR_Ig 708 237 56
PF19081 Ig_7 5,771 5,204 3,373
CL0012 Histone 126,886 42,523 15,416 PF00125 Histone 71,501 15,649 5,639
PF00808 CBFD_NFYB_HMF 19,688 10,083 3,637
PF02269 TFIID-18kDa 4,015 1,909 642
PF02291 TFIID-31kDa 2,488 1,245 444
PF02969 TAF 3,147 1,341 485
PF03540 TFIID_30kDa 2,180 1,120 389
PF03847 TFIID_20kDa 2,805 1,485 636
PF04719 TAFII28 2,361 1,309 507
PF05236 TAF4 3,370 1,703 645
PF07524 Bromo_TP 5,129 2,582 973
PF09123 DUF1931 686 206 49
PF09415 CENP-X 1,438 871 356
PF15510 CENP-W 361 189 87
PF15511 CENP-T_C 5,877 1,966 786
PF15630 CENP-S 1,550 879 345
PF15715 PAF 402 210 77
PF17027 Bromo_TP_like 48 35 28
CL0013 Beta-lactamase 497,521 229,904 59,607 PF00144 Beta-lactamase 162,194 90,800 27,545
PF00768 Peptidase_S11 64,377 25,565 6,589
PF00905 Transpeptidase 196,607 81,498 16,931
PF02113 Peptidase_S13 21,091 10,862 3,344
PF04960 Glutaminase 17,938 5,949 959
PF13354 Beta-lactamase2 35,478 15,410 4,334
CL0014 Glutaminase_I 622,087 261,123 39,290 PF00117 GATase 235,774 90,066 9,831
PF01174 SNO 13,110 6,072 696
PF01965 DJ-1_PfpI 133,395 54,210 7,407
PF02016 Peptidase_S66 22,980 10,591 1,923
PF03575 Peptidase_S51 19,201 9,892 2,244
PF04204 HTS 11,867 3,947 396
PF06283 ThuA 23,108 13,175 2,685
PF07090 GATase1_like 5,137 2,182 824
PF07685 GATase_3 41,828 17,336 2,050
PF07722 Peptidase_C26 25,510 12,364 3,393
PF08532 Glyco_hydro_42M 13,734 7,070 1,572
PF09822 ABC_transp_aux 12,026 7,392 2,822
PF09825 BPL_N 2,891 1,661 659
PF13507 GATase_5 38,155 14,905 1,414
PF13709 DUF4159 8,451 5,038 1,041
PF17124 ThiJ_like 2,049 972 165
PF17385 LBP_M 1,413 477 71
PF18011 Catalase_C 11,472 3,894 258
CL0015 MFS 1,766,020 749,233 179,249 PF00083 Sugar_tr 232,345 98,974 26,079
PF00854 PTR2 52,235 21,806 5,113
PF01306 LacY_symp 3,932 926 295
PF01733 Nucleoside_tran 6,467 3,449 1,191
PF01770 Folate_carrier 2,459 1,467 559
PF03092 BT1 6,862 3,498 1,122
PF03137 OATP 7,663 3,943 1,709
PF03209 PUCC 3,601 1,743 314
PF03219 TLC 2,792 1,731 804
PF03825 Nuc_H_symport 9,248 2,950 522
PF05631 MFS_5 2,447 1,215 496
PF05977 MFS_3 54,276 27,561 8,066
PF05978 UNC-93 4,826 2,608 967
PF06609 TRI12 3,792 2,309 839
PF06779 MFS_4 11,266 4,351 999
PF06813 Nodulin-like 5,211 2,687 758
PF06963 FPN1 2,816 1,554 629
PF07672 MFS_Mycoplasma 114 56 28
PF07690 MFS_1 1,295,179 542,243 125,030
PF11700 ATG22 17,676 9,023 1,554
PF12832 MFS_1_like 15,965 7,498 2,931
PF13000 Acatn 4,996 2,501 796
PF13347 MFS_2 47,008 19,600 5,892
CL0016 PKinase 1,561,716 812,649 292,435 PF00069 Pkinase 865,177 459,335 176,857
PF00454 PI3_PI4_kinase 32,025 15,771 5,062
PF01163 RIO1 16,071 7,874 2,093
PF01504 PIP5K 15,802 7,216 2,364
PF01633 Choline_kinase 11,981 6,083 2,297
PF01636 APH 170,538 90,487 27,106
PF02816 Alpha_kinase 5,127 2,943 1,483
PF02958 EcKinase 8,897 6,043 2,751
PF03109 ABC1 51,804 22,780 4,937
PF03770 IPK 7,544 4,044 1,617
PF03881 Fructosamin_kin 13,243 7,109 1,824
PF04183 IucA_IucC 14,243 5,530 1,004
PF04655 APH_6_hur 7,085 3,701 845
PF05445 Pox_ser-thr_kin 172 52 22
PF06090 Ins_P5_2-kin 2,461 1,431 715
PF06176 WaaY 2,148 378 204
PF06293 Kdo 20,134 8,373 2,893
PF06315 AceK 6,139 1,606 279
PF06702 Fam20C 2,183 997 350
PF06734 UL97 506 29 16
PF07387 Seadorna_VP7 48 32 17
PF07714 PK_Tyr_Ser-Thr 243,547 129,078 53,014
PF07804 HipA_C 22,862 12,140 2,897
PF07914 DUF1679 1,274 986 642
PF08757 CotH 14,021 9,951 5,337
PF09192 Act-Frag_cataly 520 231 85
PF10009 DUF2252 8,594 4,043 712
PF10140 YukC 1,495 437 206
PF10707 YrbL-PhoP_reg 2,035 745 344
PF12260 PIP49_C 2,701 1,091 401
PF12330 Haspin_kinase 2,207 1,455 751
PF13095 FTA2 647 397 219
PF13575 DUF4135 2,864 1,744 978
PF14531 Kinase-like 604 170 114
PF16474 KIND 1,896 1,022 341
PF17667 Pkinase_fungal 9,602 8,171 5,122
PF18101 Pan3_PK 2,348 1,088 354
PF18762 Kinase-PolyVal 399 249 97
CL0018 bZIP 60,037 28,717 11,129 PF00170 bZIP_1 40,214 18,724 6,904
PF03131 bZIP_Maf 5,890 2,442 818
PF07716 bZIP_2 13,932 7,723 3,832
CL0020 TPR 1,538,975 834,823 344,119 PF00514 Arm 35,842 13,908 4,319
PF00515 TPR_1 75,418 40,043 21,763
PF00613 PI3Ka 10,297 4,290 1,177
PF00637 Clathrin 12,100 4,824 1,399
PF00806 PUF 13,159 6,919 2,557
PF01239 PPTA 6,623 3,716 1,371
PF01347 Vitellogenin_N 5,010 2,843 1,443
PF01394 Clathrin_propel 3,750 1,160 184
PF01535 PPR 107,500 61,311 23,713
PF01602 Adaptin_N 27,593 11,697 2,951
PF01603 B56 8,982 3,624 948
PF01749 IBB 6,787 2,106 551
PF01816 LRV 1,096 770 373
PF01851 PC_rep 5,719 2,047 419
PF02020 W2 9,881 4,152 1,009
PF02071 NSF 3 4 4
PF02184 HAT 2,396 958 185
PF02259 FAT 9,539 5,122 1,591
PF02847 MA3 11,539 5,595 1,700
PF02854 MIF4G 16,495 8,153 2,874
PF02985 HEAT 13,550 6,427 2,949
PF03130 HEAT_PBS 6,910 4,583 2,419
PF03224 V-ATPase_H_N 3,101 1,293 386
PF03377 TAL_effector 576 276 80
PF03378 CAS_CSE1 2,676 1,154 385
PF03704 BTAD 36,730 24,844 9,978
PF03810 IBN_N 24,914 9,680 2,681
PF04049 ANAPC8 2,108 965 297
PF04050 Upf2 2,409 1,093 300
PF04184 ST7 2,403 709 201
PF04733 Coatomer_E 3,234 1,569 697
PF04818 CID 13,501 6,524 2,334
PF04826 Arm_2 1,846 780 291
PF04910 Tcf25 2,650 1,506 565
PF05004 IFRD 3,080 1,296 503
PF05484 LRV_FeS 577 350 42
PF05536 Neurochondrin 1,514 764 343
PF05804 KAP 1,961 944 434
PF05843 Suf 4,568 2,243 918
PF05918 API5 1,521 686 339
PF06041 DUF924 10,116 5,394 975
PF06367 Drf_FH3 9,132 4,453 1,250
PF06371 Drf_GBD 9,444 4,529 1,174
PF06552 TOM20_plant 1,287 748 327
PF06920 DHR-2 11,244 5,804 1,323
PF06957 COPI_C 3,056 1,148 295
PF07219 HemY_N 11,100 4,236 1,034
PF07571 TAF6_C 2,976 1,319 440
PF07719 TPR_2 50,448 30,193 19,389
PF07720 TPR_3 2,584 986 637
PF07721 TPR_4 6,289 4,557 3,282
PF07980 SusD_RagB 78,658 43,611 9,311
PF08144 CPL 2,163 1,116 320
PF08167 RIX1 1,947 1,081 472
PF08238 Sel1 78,932 41,032 20,767
PF08321 PPP5 3,442 1,424 334
PF08389 Xpo1 11,615 4,617 1,512
PF08506 Cse1 5,233 2,008 612
PF08569 Mo25 3,792 1,451 423
PF08579 RPM2 136 97 59
PF08623 TIP120 2,885 1,084 368
PF08631 SPO22 1,430 926 420
PF08713 DNA_alkylation 21,795 11,343 2,465
PF08767 CRM1_C 3,336 1,151 373
PF08852 DUF1822 1,452 968 456
PF09088 MIF4G_like 2,453 1,097 334
PF09090 MIF4G_like_2 2,521 1,139 360
PF09127 Leuk-A4-hydro_C 5,579 2,741 528
PF09246 PHAT 145 76 35
PF09268 Clathrin-link 3,239 987 140
PF09295 ChAPs 2,436 1,135 561
PF09311 Rab5-bind 1,415 454 167
PF09450 DUF2019 495 344 147
PF09613 HrpB1_HrpK 583 218 108
PF09759 Atx10homo_assoc 2,129 1,133 481
PF09976 TPR_21 16,390 7,734 3,067
PF09986 DUF2225 2,261 1,275 494
PF10037 MRP-S27 1,053 556 193
PF10255 Paf67 2,830 878 290
PF10274 ParcG 1,748 940 351
PF10300 DUF3808 4,788 2,287 862
PF10345 Cohesin_load 2,131 973 405
PF10366 Vps39_1 3,374 1,532 529
PF10373 EST1_DNA_bind 5,580 2,981 1,356
PF10374 EST1 3,950 1,987 877
PF10508 Proteasom_PSMB 1,483 678 327
PF10516 SHNi-TPR 2,344 1,236 444
PF10579 Rapsyn_N 629 232 113
PF10602 RPN7 5,244 2,161 633
PF11698 V-ATPase_H_C 2,903 1,152 307
PF11701 UNC45-central 2,349 981 273
PF11817 Foie-gras_1 2,635 1,338 505
PF11846 Wzy_C_2 2,942 1,504 544
PF11865 DUF3385 2,874 1,233 355
PF12031 BAF250_C 2,171 1,101 283
PF12243 CTK3 1,047 541 175
PF12348 CLASP_N 8,999 5,418 1,607
PF12460 MMS19_C 2,187 1,096 388
PF12569 NARP1 3,662 1,596 529
PF12688 TPR_5 3,821 2,011 622
PF12717 Cnd1 4,220 2,214 907
PF12719 Cnd3 2,482 1,311 524
PF12741 SusD-like 4,043 1,758 465
PF12753 Nro1 185 134 61
PF12755 Vac14_Fab1_bd 3,634 1,537 480
PF12765 Cohesin_HEAT 3,377 1,770 760
PF12771 SusD-like_2 12,676 8,521 1,803
PF12830 Nipped-B_C 2,786 1,496 560
PF12854 PPR_1 31,447 17,712 7,166
PF12862 ANAPC5 3,250 1,920 1,179
PF12895 ANAPC3 14,603 7,909 4,263
PF12968 DUF3856 43 35 12
PF13041 PPR_2 103,774 58,356 20,784
PF13174 TPR_6 43,202 26,364 15,020
PF13176 TPR_7 31,281 17,321 11,263
PF13181 TPR_8 187,265 111,618 62,381
PF13251 DUF4042 1,303 646 293
PF13371 TPR_9 8,948 3,620 1,415
PF13374 TPR_10 39,157 28,151 17,699
PF13414 TPR_11 63,353 40,733 23,739
PF13424 TPR_12 115,387 77,274 43,988
PF13428 TPR_14 7,805 5,139 3,703
PF13429 TPR_15 4,965 2,933 1,798
PF13431 TPR_17 7,913 5,299 3,881
PF13432 TPR_16 206,326 127,154 66,187
PF13512 TPR_18 193 140 110
PF13513 HEAT_EZ 9,941 3,874 1,019
PF13525 YfiO 28,370 14,037 4,599
PF13646 HEAT_2 63,201 39,008 18,446
PF13812 PPR_3 27,225 16,163 7,761
PF13838 Clathrin_H_link 4,527 1,375 270
PF14322 SusD-like_3 76,514 42,087 8,755
PF14559 TPR_19 115,168 64,578 34,592
PF14561 TPR_20 16,264 6,308 1,093
PF14852 Fis1_TPR_N 2,134 983 229
PF14853 Fis1_TPR_C 2,705 1,308 442
PF14863 Alkyl_sulf_dimr 8,731 3,950 758
PF14938 SNAP 6,941 3,425 1,576
PF16186 Arm_3 7,065 2,170 560
PF16416 GUN4_N 382 181 24
PF16811 TAtT 1,707 1,326 595
PF16918 PknG_TPR 2,990 1,409 283
PF17004 SRP_TPR_like 2,189 994 332
PF17177 PPR_long 8,959 5,094 2,352
PF17432 DUF3458_C 13,624 5,159 702
PF17874 TPR_MalT 23,761 13,747 7,749
PF18028 Zmiz1_N 607 228 85
PF18381 YcaO_C 5,012 875 90
PF18391 CHIP_TPR_N 829 329 118
PF18581 SYCP2_ARLD 377 225 111
PF18710 ComR_TPR 896 213 95
PF18768 RNPP_C 2,438 665 319
PF18795 HSM3_N 251 141 68
PF18806 Importin_rep_3 1,226 500 188
PF18829 Importin_rep_6 2,824 1,050 279
PF18944 DUF5691 2,226 1,171 384
PF19189 Mtf2 1,060 666 379
CL0021 OB 1,717,286 639,628 116,484 PF00164 Ribosom_S12_S23 48,193 7,419 816
PF00181 Ribosomal_L2 50,157 11,548 824
PF00313 CSD 106,048 31,171 5,153
PF00366 Ribosomal_S17 40,082 13,451 1,760
PF00436 SSB 72,771 31,226 6,940
PF00575 S1 190,089 66,180 10,708
PF00900 Ribosomal_S4e 5,640 2,249 629
PF01132 EFP 38,128 10,913 968
PF01176 eIF-1a 45,094 8,610 1,173
PF01200 Ribosomal_S28e 4,166 1,382 316
PF01287 eIF-5a 4,847 1,988 474
PF01330 RuvA_N 33,746 13,784 2,065
PF01336 tRNA_anti-codon 139,232 52,271 7,250
PF01588 tRNA_bind 79,339 31,376 4,301
PF01796 OB_aCoA_assoc 24,731 13,960 3,087
PF01938 TRAM 57,604 23,297 3,798
PF01957 NfeD 30,867 15,893 4,316
PF02303 Phage_DNA_bind 375 231 89
PF02721 DUF223 2,808 2,050 1,336
PF02760 HIN 495 192 100
PF02765 POT1 2,397 1,327 662
PF03100 CcmE 15,346 6,901 1,194
PF03120 DNA_ligase_OB 42,406 17,762 2,119
PF03319 EutN_CcmL 8,024 3,720 541
PF03459 TOBE 39,372 15,212 2,428
PF03870 RNA_pol_Rpb8 2,503 1,010 301
PF03919 mRNA_cap_C 2,927 1,459 521
PF04057 Rep-A_N 2,944 1,493 514
PF04076 BOF 5,657 1,464 441
PF04679 DNA_ligase_A_C 37,338 18,611 2,827
PF04717 Phage_base_V 36,415 15,624 4,217
PF06125 DUF961 2,840 302 91
PF06714 Gp5_OB 596 222 129
PF07076 DUF1344 1,539 453 148
PF07290 DUF1449 3,450 1,238 392
PF07404 TEBP_beta 22 13 9
PF07497 Rho_RNA_bind 30,767 9,542 908
PF07717 OB_NTP_bind 39,300 15,683 3,264
PF08206 OB_RNB 24,167 8,297 1,384
PF08292 RNA_pol_Rbc25 2,329 1,114 355
PF08402 TOBE_2 105,480 38,885 4,859
PF08418 Pol_alpha_B_N 1,758 906 286
PF08585 RMI1_N 3,433 1,971 915
PF08646 Rep_fac-A_C 6,813 4,137 2,023
PF08661 Rep_fac-A_3 2,170 1,238 483
PF08804 gp32 1,123 512 192
PF09103 BRCA-2_OB1 1,443 864 485
PF09104 BRCA-2_OB3 544 321 155
PF09285 Elong-fact-P_C 38,362 11,101 941
PF09883 DUF2110 639 302 69
PF10246 MRP-S35 658 419 161
PF10341 TPP1 568 354 216
PF10447 EXOSC1 2,208 1,123 290
PF10451 Stn1 913 568 274
PF10991 DUF2815 2,324 961 346
PF11325 DUF3127 3,941 1,969 356
PF11506 DUF3217 20 8 4
PF11604 CusF_Ec 10,307 4,783 1,226
PF11736 DUF3299 6,265 2,404 736
PF11967 RecO_N 33,420 15,145 4,213
PF12658 Ten1 552 355 127
PF12667 NigD_N 1,618 477 171
PF12857 TOBE_3 6,738 1,671 127
PF12869 tRNA_anti-like 1,727 1,299 777
PF13114 RecO_N_2 1,126 191 30
PF13509 S1_2 10,566 3,803 499
PF13742 tRNA_anti_2 32,808 14,055 2,748
PF14444 S1-like 1,303 589 210
PF14481 Fimbrial_PilY2 58 26 17
PF14743 DNA_ligase_OB_2 3,852 2,173 636
PF15072 DUF4539 1,345 843 459
PF15490 Ten1_2 780 470 201
PF16099 RMI1_C 821 495 221
PF16100 RMI2 618 358 140
PF16450 Prot_ATP_ID_OB 18,248 4,308 677
PF16669 TTC5_OB 829 401 169
PF16686 POT1PC 1,622 919 471
PF16745 RsgA_N 9,919 4,233 486
PF16773 Phage_SSB 277 18 7
PF16853 CDC13_N 50 35 25
PF16900 REPA_OB_2 4,559 2,522 1,134
PF16992 RNA_pol_RpbG 113 76 52
PF17092 PCB_OB 14,511 5,187 569
PF17185 NlpE_C 2,175 521 204
PF17191 RecG_wedge 31,912 13,370 2,256
PF17207 MCM_OB 23,833 8,873 2,295
PF17215 Rrp44_S1 2,607 979 205
PF17216 Rrp44_CSD1 3,616 1,469 415
PF17244 CDC24_OB3 491 266 132
PF17245 CDC24_OB2 382 200 77
PF17246 CDC24_OB1 359 201 88
PF17746 SfsA_N 10,879 4,958 789
PF17758 Prot_ATP_OB_N 4,236 1,011 109
PF17768 RecJ_OB 31,615 13,652 3,025
PF17845 FbpC_C_terminal 38 6 3
PF17847 GlcV_C_terminal 50 20 6
PF17849 OB_Dis3 5,826 2,635 804
PF17850 CysA_C_terminal 2,788 981 129
PF17875 RPA43_OB 1,288 775 310
PF17876 CSD2 27,322 9,772 1,492
PF17878 ssDBP 3 3 1
PF17879 DNA_ligase_C 230 86 13
PF17912 OB_MalK 47,486 14,796 1,080
PF18018 DNA_pol_D_N 2,473 1,287 414
PF18352 Gp138_N 2,625 955 363
PF18543 ID 105 82 16
PF18614 RNase_II_C_S1 3,099 1,768 158
PF18691 Cdc13_OB2 23 12 10
PF18693 TRAM_2 21,627 7,943 986
PF18914 DUF5666 4,834 3,133 1,788
CL0022 LRR 354,078 197,290 90,642 PF00560 LRR_1 50,703 31,747 15,216
PF01030 Recep_L_domain 8,165 4,097 1,666
PF03382 DUF285 8,053 5,784 3,974
PF05725 FNIP 2,244 1,860 1,233
PF07723 LRR_2 3,690 2,449 1,318
PF07725 LRR_3 3,669 2,455 1,220
PF12468 TTSSLRR 2,789 194 73
PF12799 LRR_4 21,686 12,020 7,541
PF13306 LRR_5 28,335 17,970 13,058
PF13516 LRR_6 75,234 45,646 22,304
PF13855 LRR_8 206,336 109,440 44,388
PF14580 LRR_9 15,023 7,919 3,020
PF18837 LRR_12 712 130 28
CL0023 P-loop_NTPase 9,359,902 3,911,956 890,584 PF00004 AAA 425,709 168,569 34,911
PF00005 ABC_tran 2,575,881 1,029,876 156,758
PF00006 ATP-synt_ab 191,591 45,380 3,740
PF00009 GTP_EFTU 392,550 105,178 14,005
PF00025 Arf 36,842 14,627 4,804
PF00063 Myosin_head 51,875 23,590 6,508
PF00071 Ras 143,209 58,457 19,726
PF00142 Fer4_NifH 49,793 8,409 680
PF00154 RecA 60,028 13,698 1,742
PF00158 Sigma54_activat 210,713 89,867 19,291
PF00176 SNF2_N 124,357 63,583 20,005
PF00225 Kinesin 70,872 36,704 13,160
PF00265 TK 21,235 8,304 1,179
PF00270 DEAD 466,140 200,220 43,141
PF00271 Helicase_C 677,591 296,441 65,894
PF00308 Bac_DnaA 48,239 17,847 3,556
PF00350 Dynamin_N 48,139 21,826 7,248
PF00406 ADK 56,893 24,189 4,890
PF00437 T2SSE 134,663 59,973 10,958
PF00448 SRP54 88,787 32,660 4,737
PF00485 PRK 48,562 17,463 3,371
PF00488 MutS_V 71,715 32,177 7,785
PF00493 MCM 25,424 9,876 2,886
PF00503 G-alpha 19,155 7,546 2,451
PF00519 PPV_E1_C 3,401 888 233
PF00580 UvrD-helicase 113,576 49,248 14,632
PF00625 Guanylate_kin 64,200 26,958 4,774
PF00685 Sulfotransfer_1 32,047 18,875 9,007
PF00693 Herpes_TK 1,183 122 63
PF00709 Adenylsucc_synt 42,872 13,991 1,949
PF00735 Septin 18,793 6,161 1,629
PF00910 RNA_helicase 19,162 3,643 1,951
PF00931 NB-ARC 103,286 66,370 29,172
PF01057 Parvo_NS1 4,316 748 417
PF01078 Mg_chelatase 39,548 18,673 2,500
PF01121 CoaE 38,159 19,751 4,717
PF01202 SKI 56,263 25,787 6,055
PF01268 FTHFS 24,207 9,236 1,068
PF01443 Viral_helicase1 11,688 2,870 1,317
PF01580 FtsK_SpoIIIE 65,549 29,857 6,200
PF01583 APS_kinase 28,544 12,702 2,097
PF01591 6PF2K 9,168 3,383 771
PF01637 ATPase_2 8,355 4,804 1,753
PF01656 CbiA 79,887 36,769 8,842
PF01695 IstB_IS21 44,279 17,760 6,160
PF01712 dNK 17,987 8,073 1,737
PF01715 IPPT 42,975 21,870 4,191
PF01745 IPT 625 397 290
PF01926 MMR_HSR1 307,104 121,141 20,941
PF01935 DUF87 21,700 11,975 3,802
PF02223 Thymidylate_kin 41,578 21,297 4,793
PF02224 Cytidylate_kin 33,055 15,324 2,337
PF02263 GBP 6,998 3,328 1,419
PF02283 CobU 19,344 9,110 1,576
PF02367 TsaE 34,770 17,649 3,902
PF02374 ArsA_ATPase 20,955 9,010 1,837
PF02399 Herpes_ori_bp 1,128 592 345
PF02421 FeoB_N 27,251 12,189 1,787
PF02456 Adeno_IVa2 543 150 53
PF02463 SMC_N 106,194 47,335 11,865
PF02492 cobW 77,883 29,449 4,384
PF02499 DNA_pack_C 806 144 39
PF02500 DNA_pack_N 576 101 34
PF02534 T4SS-DNA_transf 23,413 8,854 3,193
PF02562 PhoH 49,191 16,567 1,748
PF02572 CobA_CobO_BtuR 19,911 7,477 1,003
PF02606 LpxK 21,617 11,020 2,985
PF02689 Herpes_Helicase 5,602 2,743 1,469
PF02702 KdpD 15,969 5,284 661
PF02841 GBP_C 4,495 1,934 653
PF03028 Dynein_heavy 12,389 7,652 2,219
PF03029 ATP_bind_1 22,117 7,754 1,374
PF03192 DUF257 417 297 129
PF03193 RsgA_GTPase 32,721 13,899 2,146
PF03205 MobB 12,427 5,975 1,463
PF03215 Rad17 2,748 1,598 760
PF03237 Terminase_6 17,726 7,783 2,317
PF03266 NTPase_1 3,794 2,390 1,105
PF03308 MeaB 23,274 12,063 1,630
PF03354 Terminase_1 14,010 5,535 1,471
PF03567 Sulfotransfer_2 15,890 9,425 4,980
PF03618 Kinase-PPPase 16,173 5,009 655
PF03668 ATP_bind_2 23,936 8,815 1,206
PF03796 DnaB_C 52,348 19,975 5,521
PF03846 SulA 3,785 948 248
PF03969 AFG1_ATPase 22,610 8,625 1,548
PF03976 PPK2 30,379 14,010 1,231
PF04257 Exonuc_V_gamma 12,915 5,135 1,889
PF04310 MukB 3,228 368 98
PF04317 DUF463 5,905 1,695 242
PF04466 Terminase_3 6,414 3,087 995
PF04548 AIG1 13,913 9,910 4,622
PF04665 Pox_A32 1,724 518 251
PF04670 Gtr1_RagA 5,212 2,214 696
PF04851 ResIII 139,128 60,145 14,323
PF05049 IIGP 2,174 1,583 679
PF05127 Helicase_RecD 7,727 3,185 880
PF05179 CDC73_C 2,482 1,160 372
PF05272 VirE 8,947 3,251 1,511
PF05496 RuvB_N 42,057 14,647 1,178
PF05609 LAP1C 867 455 184
PF05621 TniB 4,972 2,641 1,202
PF05625 PAXNEB 2,458 1,351 490
PF05673 DUF815 10,934 4,234 498
PF05707 Zot 3,267 2,011 963
PF05729 NACHT 48,336 35,121 17,364
PF05783 DLIC 3,561 1,545 574
PF05872 DUF853 14,445 5,899 770
PF05876 Terminase_GpA 9,112 3,768 1,497
PF05879 RHD3 3,711 2,117 892
PF05894 Podovirus_Gp16 83 57 42
PF05970 PIF1 23,651 16,090 8,603
PF06048 DUF927 4,819 2,353 1,229
PF06068 TIP49 5,885 1,932 512
PF06144 DNA_pol3_delta 30,478 12,727 3,977
PF06309 Torsin 2,256 1,198 414
PF06414 Zeta_toxin 8,208 4,666 1,935
PF06418 CTP_synth_N 41,459 13,124 981
PF06431 Polyoma_lg_T_C 2,382 216 85
PF06564 CBP_BcsQ 4,729 1,779 716
PF06733 DEAD_2 21,403 9,216 2,851
PF06745 ATPase 18,176 9,762 2,946
PF06858 NOG1 3,912 1,670 347
PF06990 Gal-3-0_sulfotr 2,261 1,421 752
PF07015 VirC1 2,475 1,004 313
PF07034 ORC3_N 2,297 1,238 503
PF07088 GvpD 458 269 158
PF07517 SecA_DEAD 44,394 17,270 2,431
PF07529 HSA 7,834 4,258 1,184
PF07652 Flavi_DEAD 36,216 2,500 348
PF07693 KAP_NTPase 10,851 7,102 4,178
PF07724 AAA_2 156,763 48,248 5,911
PF07726 AAA_3 56,186 23,616 1,794
PF07728 AAA_5 60,901 26,868 7,531
PF07755 DUF1611 4,754 2,713 346
PF07931 CPT 2,742 1,753 478
PF07999 RHSP 2,575 1,753 572
PF08298 AAA_PrkA 10,470 2,222 386
PF08303 tRNA_lig_kinase 1,229 704 198
PF08351 DUF1726 6,715 2,660 638
PF08423 Rad51 16,121 7,873 2,850
PF08433 KTI12 2,957 1,788 706
PF08438 MMR_HSR1_C 3,421 1,599 217
PF08477 Roc 6,245 3,865 2,149
PF09037 Sulphotransf 1,699 880 442
PF09140 MipZ 3,450 1,543 362
PF09439 SRPRB 2,521 1,364 482
PF09547 Spore_IV_A 3,582 1,107 125
PF09711 Cas_Csn2 862 391 230
PF09807 ELP6 1,303 774 312
PF09818 ABC_ATPase 3,102 1,611 377
PF09820 AAA-ATPase_like 14,801 7,396 2,399
PF09848 DUF2075 6,324 3,823 1,189
PF10088 DUF2326 1,778 1,169 496
PF10236 DAP3 2,566 1,366 514
PF10412 TrwB_AAD_bind 10,774 5,193 1,937
PF10443 RNA12 1,136 633 186
PF10483 Elong_Iki1 1,842 1,060 372
PF10609 ParA 53,893 23,063 4,719
PF10649 DUF2478 1,631 1,126 319
PF10662 PduV-EutP 3,953 976 278
PF10923 DUF2791 3,287 1,648 400
PF10996 Beta-Casp 24,184 12,439 2,054
PF11111 CENP-M 493 259 82
PF11398 DUF2813 2,719 676 229
PF11496 HDA2-3 592 390 185
PF11602 NTPase_P4 14 10 7
PF12128 DUF3584 1,177 554 267
PF12344 UvrB 36,315 11,315 562
PF12399 BCA_ABC_TP_C 88,683 33,465 3,464
PF12696 TraG-D_C 14,516 5,911 2,283
PF12774 AAA_6 13,860 8,595 2,984
PF12775 AAA_7 12,335 7,782 2,511
PF12780 AAA_8 12,553 7,891 2,567
PF12781 AAA_9 12,864 7,871 2,521
PF12846 AAA_10 5,944 1,604 605
PF12848 ABC_tran_Xtn 110,569 31,207 3,229
PF13086 AAA_11 41,004 22,883 9,570
PF13087 AAA_12 49,962 27,371 11,201
PF13166 AAA_13 5,817 3,590 1,576
PF13173 AAA_14 34,909 20,862 5,074
PF13175 AAA_15 26,254 17,685 8,607
PF13177 DNA_pol3_delta2 78,532 37,032 9,455
PF13189 Cytidylate_kin2 12,498 6,335 2,056
PF13191 AAA_16 61,245 39,306 16,497
PF13207 AAA_17 4,339 2,879 1,171
PF13238 AAA_18 16,481 8,787 2,987
PF13245 AAA_19 40,493 20,806 6,073
PF13304 AAA_21 44,374 28,317 12,034
PF13307 Helicase_C_2 43,707 17,252 4,701
PF13337 Lon_2 2,869 1,435 298
PF13361 UvrD_C 128,665 55,996 15,836
PF13401 AAA_22 37,461 21,515 8,768
PF13469 Sulfotransfer_3 29,312 19,494 9,734
PF13476 AAA_23 46,114 26,326 12,345
PF13479 AAA_24 5,918 3,025 1,118
PF13481 AAA_25 46,467 17,698 5,821
PF13500 AAA_26 42,732 17,055 2,992
PF13514 AAA_27 6,300 3,315 1,768
PF13521 AAA_28 16,024 8,076 1,988
PF13538 UvrD_C_2 44,716 19,903 5,221
PF13555 AAA_29 6,328 2,655 958
PF13558 SbcCD_C 27,736 11,805 4,252
PF13604 AAA_30 46,484 21,081 6,207
PF13614 AAA_31 126,862 53,168 13,733
PF13654 AAA_32 11,016 4,234 976
PF13671 AAA_33 41,070 21,911 6,467
PF13871 Helicase_C_4 4,837 2,308 657
PF13872 AAA_34 4,880 2,436 725
PF13892 DBINO 2,921 1,370 368
PF14396 CFTR_R 639 214 27
PF14417 MEDS 5,513 3,971 1,516
PF14516 AAA_35 5,136 3,441 1,363
PF14532 Sigma54_activ_2 5,370 2,594 865
PF14617 CMS1 1,780 955 335
PF16203 ERCC3_RAD25_C 9,023 3,142 509
PF16575 CLP1_P 5,882 3,388 1,465
PF16796 Microtub_bd 1,369 1,005 714
PF16813 Cas_St_Csn2 178 80 49
PF16834 CSM2 51 36 23
PF16836 PSY3 91 66 43
PF17213 Hydin_ADK 296 234 122
PF17784 Sulfotransfer_4 6,729 4,136 1,831
PF18082 NAT_N 1,158 741 285
PF18128 HydF_dimer 3,190 1,612 157
PF18133 HydF_tetramer 3,254 1,657 183
PF18747 Ploopntkinase2 74 18 7
PF18748 Ploopntkinase1 87 17 11
PF18751 Ploopntkinase3 255 32 13
PF18766 SWI2_SNF2 24,165 11,550 1,733
PF19044 P-loop_TraG 22,213 6,901 1,638
CL0025 His_Kinase_A 1,482,220 743,087 262,989 PF00512 HisKA 770,466 386,728 142,677
PF02518 HATPase_c 1,183,961 580,134 208,856
PF02895 H-kinase_dim 25,375 12,220 2,590
PF07536 HWE_HK 15,849 8,547 2,726
PF07568 HisKA_2 21,675 12,330 5,543
PF07730 HisKA_3 139,002 77,980 24,914
PF10090 HPTransfase 3,380 1,619 422
PF13581 HATPase_c_2 79,804 43,774 13,174
PF13589 HATPase_c_3 66,293 32,779 8,644
PF14501 HATPase_c_5 17,502 8,353 4,640
CL0026 CU_oxidase 254,492 99,893 23,426 PF00116 COX2 98,469 26,165 3,308
PF00127 Copper-bind 21,018 11,867 3,960
PF00394 Cu-oxidase 58,531 23,385 4,296
PF00812 Ephrin 3,579 1,664 548
PF02298 Cu_bind_like 11,037 6,389 2,434
PF06481 COX_ARM 8,315 2,162 210
PF06525 SoxE 749 463 213
PF07731 Cu-oxidase_2 63,153 28,928 6,021
PF07732 Cu-oxidase_3 69,315 31,992 6,151
PF08526 PAD_N 939 361 58
PF08985 DP-EP 181 111 45
PF12306 PixA 1,195 521 196
PF13473 Cupredoxin_1 25,712 12,678 4,074
PF14699 hGDE_N 1,898 885 168
PF16986 CzcE 450 271 142
CL0027 RdRP 757,653 354,924 172,484 PF00078 RVT_1 572,101 290,097 138,575
PF00680 RdRP_1 52,314 6,643 2,599
PF00972 Flavi_NS5 13,321 708 200
PF00978 RdRP_2 8,967 1,640 769
PF00998 RdRP_3 46,937 6,029 1,085
PF02123 RdRP_4 5,437 826 509
PF04197 Birna_RdRp 1,005 44 25
PF05919 Mitovir_RNA_pol 1,320 935 735
PF07727 RVT_2 56,487 48,254 28,258
PF17501 Viral_RdRp_C 19 8 3
CL0028 AB_hydrolase 1,710,767 893,949 245,722 PF00135 COesterase 66,687 39,977 15,284
PF00151 Lipase 9,761 5,657 2,549
PF00326 Peptidase_S9 135,724 73,436 19,352
PF00450 Peptidase_S10 35,636 19,786 6,455
PF00561 Abhydrolase_1 330,783 168,849 41,035
PF00756 Esterase 78,673 37,413 9,202
PF00975 Thioesterase 49,154 25,852 11,051
PF01083 Cutinase 12,646 6,057 1,670
PF01674 Lipase_2 5,467 3,009 878
PF01738 DLH 70,840 36,709 8,208
PF01764 Lipase_3 32,073 18,578 7,820
PF02089 Palm_thioest 6,652 3,578 1,284
PF02129 Peptidase_S15 40,900 20,431 4,669
PF02230 Abhydrolase_2 32,142 17,435 4,655
PF02273 Acyl_transf_2 250 125 70
PF02450 LCAT 8,446 4,785 2,155
PF03096 Ndr 6,044 2,063 655
PF03283 PAE 5,826 3,074 1,216
PF03403 PAF-AH_p_II 10,173 6,274 2,140
PF03583 LIP 13,219 6,509 1,802
PF03893 Lipase3_N 1,854 914 177
PF03959 FSH1 8,746 5,268 2,279
PF04083 Abhydro_lipase 5,535 3,632 1,583
PF04301 DUF452 1,499 492 215
PF05057 DUF676 10,780 6,367 2,846
PF05277 DUF726 4,986 2,603 868
PF05448 AXE1 10,289 5,818 1,753
PF05576 Peptidase_S37 1,873 847 186
PF05577 Peptidase_S28 9,150 5,656 2,287
PF05677 DUF818 274 187 131
PF05705 DUF829 4,356 2,531 1,131
PF05728 UPF0227 10,983 3,915 893
PF05990 DUF900 6,721 3,698 1,500
PF06028 DUF915 4,505 1,636 614
PF06057 VirJ 3,484 1,215 385
PF06259 Abhydrolase_8 6,159 3,638 1,049
PF06342 DUF1057 447 313 191
PF06441 EHN 15,669 8,814 1,306
PF06500 DUF1100 6,028 2,536 681
PF06821 Ser_hydrolase 13,284 6,151 1,421
PF06850 PHB_depo_C 7,013 2,833 405
PF07082 DUF1350 1,349 689 205
PF07167 PhaC_N 12,570 5,537 697
PF07176 DUF1400 1,856 1,092 366
PF07224 Chlorophyllase 1,310 818 344
PF07519 Tannase 11,112 6,145 1,980
PF07819 PGAP1 8,474 4,917 2,305
PF07859 Abhydrolase_3 127,328 69,578 20,645
PF08237 PE-PPE 4,139 2,200 763
PF08386 Abhydrolase_4 16,859 10,554 4,271
PF08538 DUF1749 2,100 1,187 415
PF08840 BAAT_C 5,595 3,216 1,184
PF09752 DUF2048 2,220 1,040 430
PF09994 DUF2235 13,700 8,633 3,135
PF10081 Abhydrolase_9 3,402 1,740 353
PF10142 PhoPQ_related 2,724 1,187 563
PF10230 LIDHydrolase 2,449 1,444 673
PF10340 Say1_Mug180 592 396 234
PF10503 Esterase_PHB 17,931 11,255 3,776
PF11144 DUF2920 4,904 575 162
PF11187 DUF2974 4,172 1,658 964
PF11288 DUF3089 2,377 1,671 517
PF11339 DUF3141 2,175 1,169 221
PF12048 DUF3530 2,459 1,063 418
PF12146 Hydrolase_4 152,074 77,649 25,302
PF12695 Abhydrolase_5 3,655 1,955 710
PF12697 Abhydrolase_6 234,297 129,322 36,211
PF12715 Abhydrolase_7 1,972 1,195 396
PF12740 Chlorophyllase2 4,250 2,692 1,122
PF16929 Asp2 1,100 442 202
CL0029 Cupin 1,255,825 599,223 149,523 PF00027 cNMP_binding 207,443 104,855 32,458
PF00190 Cupin_1 21,327 9,991 2,853
PF00908 dTDP_sugar_isom 33,886 18,378 1,832
PF01050 MannoseP_isomer 25,226 11,539 1,827
PF01238 PMI_typeI 20,972 9,157 1,902
PF01987 AIM24 21,818 7,979 1,242
PF02041 Auxin_BP 491 290 103
PF02311 AraC_binding 99,255 41,787 13,456
PF02373 JmjC 23,618 11,817 4,059
PF02375 JmjN 10,400 5,221 1,442
PF02668 TauD 55,404 27,280 7,042
PF02678 Pirin 52,180 22,118 2,083
PF03079 ARD 8,342 3,448 602
PF03171 2OG-FeII_Oxy 60,718 30,136 6,651
PF03336 Pox_C4_C10 284 70 44
PF04074 DUF386 11,786 3,348 1,097
PF04115 Ureidogly_lyase 8,757 3,594 704
PF04209 HgmA 15,486 5,384 565
PF04622 ERG2_Sigma1R 1,845 963 218
PF04831 Popeye 1,724 863 362
PF04962 KduI 16,699 5,987 547
PF05118 Asp_Arg_Hydrox 12,099 4,880 1,543
PF05523 FdtA 6,036 4,042 771
PF05721 PhyH 56,848 34,035 8,863
PF05726 Pirin_C 31,258 13,941 1,439
PF05899 Cupin_3 19,213 6,308 1,322
PF05962 HutD 7,681 3,507 1,037
PF05995 CDO_I 10,238 4,851 1,142
PF06052 3-HAO 5,345 2,517 320
PF06172 Cupin_5 9,565 5,223 851
PF06249 EutQ 3,820 1,322 302
PF06339 Ectoine_synth 4,817 1,600 145
PF06560 GPI 2,330 1,333 339
PF06719 AraC_N 16,994 6,662 1,173
PF06865 Ppnp 7,275 2,208 147
PF07350 DUF1479 4,398 1,478 336
PF07385 Lyx_isomer 2,692 1,149 113
PF07847 PCO_ADO 2,821 1,483 564
PF07883 Cupin_2 196,220 94,498 20,287
PF08007 Cupin_4 13,505 5,860 1,839
PF08487 VIT 10,367 6,487 2,526
PF08943 CsiD 2,072 315 59
PF09313 DUF1971 4,265 1,049 206
PF09859 Oxygenase-NA 4,442 2,170 149
PF10014 2OG-Fe_Oxy_2 4,136 1,973 466
PF10637 Ofd1_CTDD 2,024 1,111 339
PF11699 CENP-C_C 1,488 869 430
PF12851 Tet_JBP 1,543 856 302
PF12852 Cupin_6 19,047 8,691 1,658
PF12933 FTO_NTD 683 214 64
PF12973 Cupin_7 12,186 6,639 1,352
PF13532 2OG-FeII_Oxy_2 30,136 15,632 3,591
PF13621 Cupin_8 19,232 10,890 3,900
PF13640 2OG-FeII_Oxy_3 39,263 20,118 6,462
PF13661 2OG-FeII_Oxy_4 3,256 1,905 706
PF13757 VIT_2 552 336 80
PF13759 2OG-FeII_Oxy_5 5,074 3,644 1,652
PF14226 DIOX_N 55,832 27,919 5,990
PF14499 DUF4437 1,480 898 294
PF14525 AraC_binding_2 20,931 10,145 3,754
PF16161 DUF4867 1,320 524 118
PF16802 DUF5070 28 15 3
PF16867 DMSP_lyase 1,782 933 307
PF17954 Pirin_C_2 18,502 6,960 717
PF18637 AUDH_Cupin 120 93 46
CL0030 Ion_channel 265,666 130,304 39,686 PF00060 Lig_chan 25,120 12,321 4,802
PF00520 Ion_trans 108,323 56,059 16,329
PF01007 IRK 7,369 2,408 679
PF02386 TrkH 43,579 19,263 4,122
PF03814 KdpA 16,052 4,787 518
PF07885 Ion_trans_2 59,177 32,381 12,146
PF08016 PKD_channel 7,204 4,210 2,010
CL0031 Phosphatase 491,846 231,062 57,881 PF00102 Y_phosphatase 41,760 21,325 7,812
PF00581 Rhodanese 209,577 102,737 22,324
PF00782 DSPc 49,820 25,782 9,662
PF01451 LMWPc 68,410 34,437 5,887
PF02302 PTS_IIB 59,118 15,151 2,396
PF02383 Syja_N 12,850 6,300 1,832
PF03162 Y_phosphatase2 4,969 2,848 1,097
PF04179 Init_tRNA_PT 1,448 810 244
PF04273 DUF442 8,915 4,451 1,067
PF04722 Ssu72 2,414 1,103 240
PF05706 CDKN3 1,609 903 402
PF06602 Myotub-related 13,168 5,522 1,746
PF13350 Y_phosphatase3 18,952 10,011 3,498
PF14566 PTPlike_phytase 2,413 1,169 472
PF14671 DSPn 3,378 1,538 461
PF16809 NleF_casp_inhib 106 31 17
CL0032 Dim_A_B_barrel 448,685 189,295 34,750 PF01037 AsnC_trans_reg 145,965 45,137 6,280
PF02426 MIase 4,894 1,662 285
PF03795 YCII 52,619 26,380 3,979
PF03927 NapD 3,842 1,627 527
PF03992 ABM 76,971 36,539 8,422
PF04261 Dyp_perox 20,232 7,242 1,016
PF04486 SchA_CurD 809 358 33
PF04673 Cyclase_polyket 1,493 640 46
PF05336 rhaM 13,099 6,157 678
PF06778 Chlor_dismutase 8,863 3,273 369
PF07045 DUF1330 17,151 8,915 1,777
PF07110 EthD 10,048 5,793 1,821
PF07237 DUF1428 5,003 2,457 203
PF07682 SOR 93 47 15
PF07876 Dabb 18,836 10,127 2,524
PF07978 NIPSNAP 15,987 7,708 1,522
PF08734 GYD 5,637 2,891 645
PF08803 ydhR 2,706 1,019 232
PF09448 MmlI 921 506 181
PF11639 HapK 386 253 59
PF11695 DUF3291 2,889 1,907 353
PF13816 Dehydratase_hem 1,477 662 183
PF13826 DUF4188 2,841 1,688 353
PF14026 DUF4242 4,800 2,609 377
PF16291 DUF4937 1,484 340 143
PF17805 AsnC_trans_reg2 6,796 3,865 591
PF18075 FtsX_ECD 23,911 9,974 2,263
PF18232 Chalcone_N 91 47 11
CL0033 POZ 162,263 77,174 32,787 PF00651 BTB 117,561 59,087 26,017
PF02214 BTB_2 26,847 10,512 3,519
PF03931 Skp1_POZ 8,476 4,111 1,616
PF07707 BACK 39,552 14,823 5,451
PF11822 DUF3342 724 351 165
PF16017 BTB_3 1,259 409 109
CL0034 Amidohydrolase 741,629 343,657 68,033 PF00449 Urease_alpha 16,661 3,971 468
PF00962 A_deaminase 39,773 16,301 3,193
PF01026 TatD_DNase 67,322 30,215 5,878
PF01244 Peptidase_M19 28,926 14,635 3,200
PF01876 RNase_P_p30 3,482 2,054 759
PF01979 Amidohydro_1 282,587 125,379 21,473
PF02126 PTE 8,295 3,739 956
PF02614 UxaC 11,210 4,713 502
PF02811 PHP 106,451 47,535 9,378
PF04909 Amidohydro_2 97,215 51,615 11,825
PF07969 Amidohydro_3 88,570 42,369 9,826
PF12228 DUF3604 4,165 3,096 1,079
PF12890 DHOase 371 259 112
PF13263 PHP_C 8,402 5,159 1,635
CL0035 Peptidase_MH 605,764 281,342 61,896 PF00246 Peptidase_M14 53,844 30,554 9,200
PF00274 Glycolytic 13,269 5,528 760
PF00883 Peptidase_M17 42,888 18,815 3,317
PF01520 Amidase_3 59,389 28,314 9,467
PF01546 Peptidase_M20 258,503 110,382 17,964
PF02127 Peptidase_M18 15,790 6,517 1,084
PF04389 Peptidase_M28 71,210 41,570 11,297
PF04952 AstE_AspA 30,399 12,922 2,845
PF05013 FGase 19,006 9,562 1,671
PF05343 Peptidase_M42 26,143 10,394 2,002
PF05450 Nicastrin 1,746 841 379
PF05908 Gamma_PGA_hydro 2,290 986 350
PF07454 SpoIIP 4,896 2,184 821
PF10994 DUF2817 2,517 1,398 449
PF16254 DUF4910 2,185 1,101 299
PF17033 Peptidase_M99 1,628 351 105
PF18266 Ncstrn_small 1,297 636 292
CL0036 TIM_barrel 2,574,517 1,064,238 165,760 PF00121 TIM 50,149 20,325 2,964
PF00215 OMPdecase 47,658 19,697 2,750
PF00218 IGPS 36,647 14,650 2,053
PF00290 Trp_syntA 34,894 14,738 1,909
PF00478 IMPDH 56,615 15,833 1,487
PF00490 ALAD 32,932 11,495 857
PF00682 HMGL-like 121,993 45,370 4,549
PF00697 PRAI 31,090 15,311 3,067
PF00701 DHDPS 97,459 39,849 5,962
PF00724 Oxidored_FMN 103,989 43,698 6,726
PF00793 DAHP_synth_1 64,271 22,171 1,828
PF00809 Pterin_bind 72,736 30,768 3,967
PF00834 Ribul_P_3_epim 45,435 17,546 2,583
PF00923 TAL_FSA 45,507 16,472 2,069
PF00977 His_biosynth 68,509 25,172 2,906
PF01070 FMN_dh 48,314 20,584 3,661
PF01081 Aldolase 33,330 13,535 2,007
PF01116 F_bP_aldolase 46,483 14,063 1,667
PF01168 Ala_racemase_N 105,546 48,799 7,869
PF01180 DHO_dh 54,178 23,298 3,497
PF01207 Dus 69,523 27,499 4,571
PF01261 AP_endonuc_2 178,777 82,187 15,990
PF01474 DAHP_synth_2 15,901 4,984 612
PF01487 DHquinase_I 13,087 5,791 1,822
PF01645 Glu_synthase 50,946 18,671 1,771
PF01680 SOR_SNZ 13,780 3,678 268
PF01729 QRPTase_C 34,841 15,607 1,806
PF01791 DeoC 47,545 18,288 2,063
PF01884 PcrB 5,649 2,996 388
PF01964 ThiC_Rad_SAM 24,828 7,505 611
PF02007 MtrH 901 530 153
PF02581 TMP-TENI 46,817 22,508 4,560
PF02679 ComA 3,252 1,912 341
PF02784 Orn_Arg_deC_N 74,440 27,985 4,114
PF03060 NMO 58,277 25,471 2,935
PF03102 NeuB 17,485 10,087 1,752
PF03437 BtpA 4,929 2,337 500
PF03599 CdhD 4,045 2,692 554
PF03740 PdxJ 20,243 8,187 483
PF03786 UxuA 12,869 5,244 585
PF03851 UvdE 5,010 2,507 500
PF03932 CutC 14,967 6,237 1,347
PF04055 Radical_SAM 558,957 252,424 49,153
PF04095 NAPRTase 27,229 9,050 936
PF04131 NanE 7,847 2,604 317
PF04309 G3P_antiterm 4,816 1,724 360
PF04476 4HFCP_synth 2,001 1,114 358
PF04481 DUF561 939 521 116
PF04898 Glu_syn_central 32,063 10,956 1,090
PF05114 DUF692 11,554 6,004 853
PF05690 ThiG 24,004 7,629 473
PF06134 RhaA 4,407 1,375 124
PF06187 DUF993 3,866 1,561 99
PF07071 KDGP_aldolase 3,494 494 69
PF08013 GatZ_KbaZ-like 5,074 1,436 268
PF09043 Lys-AminoMut_A 1,700 802 101
PF09863 DUF2090 4,481 1,251 181
PF16154 DUF4862 1,582 316 98
PF16552 OAM_alpha 409 248 26
PF17285 PRMT5_TIM 2,663 1,172 368
CL0037 Lysozyme 355,306 155,065 41,481 PF00062 Lys 3,216 1,672 664
PF00182 Glyco_hydro_19 13,672 5,506 1,688
PF00912 Transgly 107,084 45,112 8,447
PF00959 Phage_lysozyme 18,542 6,575 2,024
PF01374 Glyco_hydro_46 1,865 970 243
PF01464 SLT 120,310 55,389 17,317
PF01832 Glucosaminidase 30,235 12,404 4,360
PF03998 Utp11 2,387 1,332 369
PF05497 Destabilase 789 601 299
PF05838 Glyco_hydro_108 6,225 3,070 979
PF06737 Transglycosylas 10,989 5,512 1,058
PF06871 TraH_2 496 265 31
PF10464 Peptidase_U40 37 5 3
PF11508 DUF3218 28 4 3
PF13406 SLT_2 30,031 13,294 2,329
PF13647 Glyco_hydro_80 19 7 4
PF13702 Lysozyme_like 5,032 1,047 365
PF16754 Pesticin 522 375 246
PF18013 Phage_lysozyme2 3,492 1,686 1,021
PF18896 SLT_3 386 299 167
CL0039 HUP 1,432,473 630,584 113,696 PF00133 tRNA-synt_1 141,529 60,924 9,235
PF00579 tRNA-synt_1b 94,455 37,870 4,039
PF00582 Usp 163,761 84,384 24,029
PF00733 Asn_synthase 58,662 31,328 10,249
PF00749 tRNA-synt_1c 88,406 38,023 4,689
PF00750 tRNA-synt_1d 45,602 19,430 3,202
PF00764 Arginosuc_synth 35,614 10,087 1,071
PF00875 DNA_photolyase 34,520 18,241 3,002
PF01012 ETF 81,602 30,305 3,833
PF01171 ATP_bind_3 60,904 29,371 8,759
PF01406 tRNA-synt_1e 50,046 21,891 2,874
PF01467 CTP_transf_like 115,992 53,106 10,226
PF01507 PAPS_reduct 57,025 20,892 3,305
PF01747 ATP-sulfurylase 11,144 4,950 586
PF01902 Diphthami_syn_2 9,026 5,512 1,377
PF01921 tRNA-synt_1f 8,017 3,613 521
PF02540 NAD_synthase 80,738 31,219 3,496
PF02568 ThiI 16,137 6,145 1,268
PF02569 Pantoate_ligase 30,933 14,567 1,922
PF03054 tRNA_Me_trans 43,423 17,106 2,714
PF03720 UDPG_MGDP_dh_C 67,387 32,444 3,084
PF04244 DPRP 8,498 4,814 502
PF05636 HIGH_NTase1 7,227 2,985 981
PF06508 QueC 24,644 10,502 1,545
PF06574 FAD_syn 35,389 15,741 3,372
PF08218 Citrate_ly_lig 4,262 1,102 322
PF09334 tRNA-synt_1g 76,565 31,422 4,095
PF10079 BshC 5,238 3,188 976
PF13603 tRNA-synt_1_2 39,758 16,075 1,257
PF16581 HIGH_NTase1_ass 148 96 13
PF16715 CDPS 858 483 233
CL0040 tRNA_synt_II 593,442 239,004 35,412 PF00152 tRNA-synt_2 121,895 46,771 6,184
PF00587 tRNA-synt_2b 154,273 59,039 5,072
PF01409 tRNA-synt_2d 45,485 16,704 1,852
PF01411 tRNA-synt_2c 55,486 23,694 3,914
PF02091 tRNA-synt_2e 19,755 4,926 379
PF03099 BPL_LplA_LipB 82,229 39,375 9,468
PF03590 AsnA 6,903 1,858 147
PF04017 DUF366 502 315 79
PF13393 tRNA-synt_His 63,209 27,098 4,408
PF16917 BPL_LplA_LipB_2 1,157 739 220
PF17759 tRNA_synthFbeta 42,624 18,586 3,828
CL0041 Death 37,151 18,155 7,186 PF00531 Death 17,598 8,545 3,226
PF00619 CARD 11,129 5,605 2,279
PF01335 DED 3,127 1,394 486
PF02758 PYRIN 4,739 2,555 1,221
PF14786 Death_2 213 140 74
PF16739 CARD_2 1,350 549 192
PF18461 Atypical_Card 266 97 33
CL0042 Flavoprotein 257,841 108,251 19,091 PF00258 Flavodoxin_1 60,805 22,627 4,126
PF02525 Flavodoxin_2 58,097 22,134 3,551
PF03358 FMN_red 107,750 49,382 7,589
PF07972 Flavodoxin_NdrI 8,418 2,338 234
PF12641 Flavodoxin_3 2,239 1,033 382
PF12682 Flavodoxin_4 7,399 4,112 1,409
PF12724 Flavodoxin_5 13,176 6,872 2,260
CL0043 Chelatase 238,431 104,747 22,327 PF00148 Oxidored_nitro 24,807 9,742 1,419
PF00762 Ferrochelatase 31,831 13,092 1,869
PF01297 ZnuA 49,379 21,839 5,347
PF01497 Peripla_BP_2 111,233 49,592 11,238
PF01903 CbiX 16,399 8,773 1,927
PF06180 CbiK 4,684 1,691 525
PF11844 DUF3364 1,848 492 21
CL0044 Ferritin 289,512 118,742 21,319 PF00210 Ferritin 68,776 24,398 3,216
PF00268 Ribonuc_red_sm 35,067 8,905 1,188
PF01786 AOX 4,037 2,216 522
PF02332 Phenol_Hydrox 5,866 1,720 230
PF02915 Rubrerythrin 29,244 14,653 2,842
PF03232 COQ7 9,469 4,406 600
PF03405 FA_desaturase_2 7,918 2,473 392
PF03713 DUF305 18,691 10,504 2,193
PF04305 DUF455 7,147 3,728 600
PF05067 Mn_catalase 10,898 3,667 407
PF05138 PaaA_PaaC 17,101 6,499 517
PF05974 DUF892 11,982 5,105 1,078
PF06175 MiaE 8,226 2,650 229
PF07875 Coat_F 6,219 2,805 622
PF09537 DUF2383 6,420 3,426 864
PF09968 DUF2202 1,263 991 523
PF11266 Ald_deCOase 709 290 44
PF11553 DUF3231 3,773 2,146 516
PF11583 AurF 8,360 2,880 532
PF12902 Ferritin-like 2,012 1,313 468
PF13628 DUF4142 12,196 6,293 2,137
PF13668 Ferritin_2 8,382 5,098 1,240
PF13794 MiaE_2 3,164 1,078 148
PF14530 DUF4439 2,663 1,520 364
PF18536 DUF5623 162 108 50
CL0045 Rubredoxin 42,171 19,641 3,005 PF00301 Rubredoxin 21,082 8,350 897
PF01215 COX5B 2,607 1,377 356
PF06397 Desulfoferrod_N 3,622 2,070 239
PF08421 Methyltransf_13 6,304 3,772 765
PF10276 zf-CHCC 8,553 4,074 753
CL0046 Thiolase 447,811 187,610 37,656 PF00108 Thiolase_N 157,719 53,958 4,530
PF00109 ketoacyl-synt 169,755 81,326 22,325
PF00195 Chal_sti_synt_N 15,731 6,163 1,023
PF01154 HMG_CoA_synt_N 9,015 3,698 549
PF02797 Chal_sti_synt_C 15,823 6,419 1,076
PF02801 Ketoacyl-synt_C 162,432 77,071 19,972
PF02803 Thiolase_C 155,081 52,367 3,593
PF07451 SpoVAD 4,650 1,736 183
PF08392 FAE1_CUT1_RppA 6,380 3,014 802
PF08540 HMG_CoA_synt_C 8,564 3,427 551
PF08541 ACP_syn_III_C 68,474 28,358 3,444
PF08545 ACP_syn_III 60,493 24,498 2,946
PF13723 Ketoacyl-synt_2 5,331 2,552 673
PF16197 KAsynt_C_assoc 52,632 33,679 13,477
CL0047 CuAO_N2_N3 9,942 4,502 812 PF02727 Cu_amine_oxidN2 8,023 3,519 630
PF02728 Cu_amine_oxidN3 8,025 3,475 533
PF09248 DUF1965 812 478 126
CL0048 LolA_LolB 93,312 48,031 16,738 PF03548 LolA 22,670 10,346 3,184
PF03550 LolB 8,712 3,460 1,173
PF03888 MucB_RseB 7,386 2,886 907
PF04507 DUF576 1,383 376 98
PF07044 DUF1329 8,939 3,421 614
PF07161 LppX_LprAFG 1,991 1,145 398
PF07608 DUF1571 1,295 792 390
PF09697 Porph_ging 6,724 4,605 1,829
PF09865 DUF2092 1,863 1,335 636
PF11306 DUF3108 14,828 8,446 3,214
PF11659 DUF3261 2,089 989 384
PF14125 DUF4292 3,739 2,429 1,048
PF14371 DUF4412 1,430 1,205 766
PF16584 LolA_2 1,227 608 216
PF17131 LolA_like 8,943 5,975 1,982
PF18234 VioE 80 44 8
CL0049 Tudor 227,478 117,829 43,610 PF00385 Chromo 32,899 18,948 8,797
PF00565 SNase 30,414 18,236 7,845
PF00567 TUDOR 11,740 6,588 3,238
PF00855 PWWP 19,141 9,001 3,312
PF01393 Chromo_shadow 3,708 1,930 871
PF02294 7kD_DNA_binding 80 13 4
PF02820 MBT 6,464 2,695 930
PF04397 LytTR 80,877 41,832 12,775
PF05641 Agenet 6,809 3,090 1,316
PF06003 SMN 2,619 1,289 506
PF07039 DUF1325 2,388 1,206 458
PF08169 RBB1NT 1,159 631 173
PF08605 Rad9_Rad53_bind 269 181 92
PF09038 53-BP1_Tudor 629 297 102
PF09465 LBR_tudor 641 268 116
PF11160 Hva1_TUDOR 5,587 3,147 483
PF11515 Cul7 1,241 631 150
PF11717 Tudor-knot 8,223 3,826 1,277
PF12148 TTD 996 400 81
PF14061 Mtf2_C 1,119 350 109
PF15057 DUF4537 600 375 201
PF16090 DUF4819 617 380 154
PF16719 SAWADEE 1,411 735 341
PF17516 ProQ_C 2,498 422 51
PF18104 Tudor_2 3,312 1,395 274
PF18115 Tudor_3 1,328 674 262
PF18336 Tudor_FRX1 2,058 617 122
PF18337 Tudor_RapA 5,998 1,235 200
PF18339 Tudor_1_RapA 6,052 1,298 217
PF18358 Tudor_4 789 432 169
PF18359 TUDOR_5 749 426 187
PF18380 GEN1_C 939 607 218
PF18704 Chromo_2 435 272 96
CL0050 HotDog 465,903 211,370 45,751 PF01575 MaoC_dehydratas 84,222 36,735 5,956
PF01643 Acyl-ACP_TE 10,703 5,211 1,912
PF02551 Acyl_CoA_thio 511 286 187
PF03061 4HBT 167,694 73,999 14,365
PF03756 AfsA 2,604 1,546 649
PF07977 FabA 46,753 17,421 2,729
PF09500 YiiD_C 4,969 1,487 379
PF10862 FcoT 368 196 55
PF13279 4HBT_2 44,519 21,466 5,115
PF13452 MaoC_dehydrat_N 23,704 11,511 2,236
PF13622 4HBT_3 34,812 14,490 3,033
PF14539 DUF4442 11,548 5,294 970
PF14765 PS-DH 39,659 25,729 10,531
CL0051 NTF2 319,873 164,392 46,735 PF00866 Ring_hydroxyl_B 10,828 4,048 802
PF02136 NTF2 12,084 5,632 1,853
PF02982 Scytalone_dh 931 469 133
PF03284 PHZA_PHZB 542 217 51
PF04280 Tim44 15,567 6,846 1,509
PF04335 VirB8 11,661 3,146 921
PF05223 MecA_N 7,224 2,875 542
PF05494 MlaC 14,600 6,904 2,107
PF07080 DUF1348 8,228 3,292 202
PF07107 WI12 704 434 123
PF07366 SnoaL 21,463 12,768 4,209
PF07858 LEH 2,430 1,333 393
PF07961 MBA1 483 278 145
PF08332 CaMKII_AD 7,606 3,698 622
PF10184 DUF2358 3,016 1,709 618
PF10429 Mtr2 209 128 51
PF11393 T4BSS_DotI_IcmL 1,688 714 354
PF11533 DUF3225 2,612 1,197 161
PF12642 TpcC 3,277 1,052 454
PF12680 SnoaL_2 82,575 44,845 11,487
PF12707 DUF3804 56 39 21
PF12870 DUF4878 1,783 1,115 710
PF12883 DUF3828 4,231 1,046 426
PF12893 Lumazine_bd_2 6,182 3,780 1,070
PF13026 DUF3887 2,451 1,296 600
PF13474 SnoaL_3 17,072 9,687 3,544
PF13577 SnoaL_4 30,398 17,525 5,530
PF14254 DUF4348 635 269 109
PF14534 DUF4440 29,881 19,054 7,154
PF14729 DUF4467 304 94 33
PF15008 DUF4518 490 303 115
PF16022 DUF4783 1,368 891 393
PF16111 DUF4829 297 227 143
PF16156 DUF4864 2,171 1,262 445
PF16247 DUF4904 11 6 2
PF16800 Endopep_inhib 662 230 122
PF17117 DUF5104 405 224 134
PF17118 DUF5105 788 247 160
PF17775 UPF0225 12,811 6,160 889
PF18042 ORF_12_N 665 274 70
CL0052 NTN 393,298 164,328 32,907 PF00227 Proteasome 74,142 25,836 4,430
PF00310 GATase_2 33,252 11,569 1,403
PF01019 G_glu_transpept 55,017 26,792 5,372
PF01112 Asparaginase_2 21,125 10,566 2,160
PF01804 Penicil_amidase 23,449 13,097 3,780
PF02275 CBAH 12,061 4,641 1,233
PF03417 AAT 9,849 5,763 1,947
PF03577 Peptidase_C69 11,155 4,052 975
PF04916 Phospholip_B 2,572 1,451 647
PF07826 IMP_cyclohyd 2,326 1,048 139
PF09147 DUF1933 47 27 16
PF10584 Proteasome_A_N 19,018 5,993 1,045
PF12481 DUF3700 1,678 800 221
PF13230 GATase_4 14,576 5,322 969
PF13522 GATase_6 66,343 23,130 2,972
PF13537 GATase_7 65,535 30,844 7,330
CL0053 4H_Cytokine 16,249 6,459 2,170 PF00103 Hormone_1 3,475 1,005 297
PF00143 Interferon 2,800 1,195 384
PF00489 IL6 527 234 125
PF00714 IFN-gamma 431 146 50
PF00715 IL2 236 60 10
PF00726 IL10 1,157 448 138
PF00727 IL4 387 140 42
PF00758 EPO_TPO 686 334 115
PF01109 GM_CSF 142 57 18
PF01110 CNTF 254 129 43
PF01291 LIF_OSM 374 185 71
PF01415 IL7 309 84 25
PF02024 Leptin 476 152 44
PF02025 IL5 176 86 18
PF02059 IL3 86 35 18
PF02372 IL15 694 368 136
PF02404 SCF 621 274 92
PF02947 Flt3_lig 191 96 37
PF03039 IL12 389 188 80
PF03487 IL13 146 59 20
PF05337 CSF-1 419 199 55
PF06875 PRF 500 149 46
PF07400 IL11 326 151 64
PF14565 IL22 263 142 41
PF15036 IL34 320 152 45
PF15177 IL28A 409 208 86
PF15216 TSLP 91 51 37
PF16647 GCSF 213 90 32
PF16649 IL23 125 57 19
CL0054 Knottin_1 6,774 3,705 1,507 PF00304 Gamma-thionin 2,562 1,337 501
PF00451 Toxin_2 227 163 64
PF00537 Toxin_3 878 537 167
PF01097 Defensin_2 948 528 248
PF05294 Toxin_5 39 26 5
PF05453 Toxin_6 35 18 6
PF06876 SCRL 459 281 144
PF07333 SLR1-BP 896 472 244
PF08086 Toxin_17 33 18 2
PF09132 BmKX 16 14 10
PF10868 Defensin_like 306 155 60
PF11415 Toxin_37 165 27 6
PF14865 Macin 73 67 34
PF14866 Toxin_38 118 59 20
PF18251 Defensin_5 4 5 4
CL0055 Nucleoplasmin 206,891 23,748 7,118 PF00073 Rhv 82,379 4,926 1,036
PF00500 Late_protein_L1 6,074 1,408 199
PF00688 TGFb_propeptide 11,187 3,741 1,315
PF00718 Polyoma_coat 5,453 257 125
PF00729 Viral_coat 1,349 353 258
PF00738 Polyhedrin 629 69 14
PF00760 Cucumo_coat 2,708 659 175
PF00894 Luteo_coat 2,853 223 72
PF00915 Calici_coat 36,042 1,185 293
PF00983 Tymo_coat 499 114 50
PF01318 Bromo_coat 21 8 3
PF01766 Birna_VP2 4,558 269 43
PF01787 Ilar_coat 1,020 92 34
PF01829 Peptidase_A6 19 18 9
PF02226 Pico_P1A 21,129 793 89
PF02247 Como_LCP 300 80 53
PF02248 Como_SCP 273 61 38
PF02443 Circo_capsid 4,656 241 92
PF02956 TT_ORF1 5,224 1,183 335
PF03014 SP2 11,020 311 50
PF03066 Nucleoplasmin 1,877 927 288
PF03115 Astro_capsid_N 3,796 510 180
PF03340 Pox_Rif 170 41 10
PF03391 Nepo_coat 789 114 60
PF03566 Peptidase_A21 44 19 14
PF03678 Adeno_hexon_C 2,958 225 32
PF03688 Nepo_coat_C 755 105 59
PF03689 Nepo_coat_N 766 102 50
PF03898 TNV_CP 78 75 67
PF08435 Calici_coat_C 8,471 213 55
PF08462 Carmo_coat_C 66 4 2
PF08762 CRPV_capsid 1,394 495 362
PF08935 VP4_2 2,184 251 36
PF11175 DUF2961 4,808 2,785 812
PF11492 Dicistro_VP4 413 275 185
PF11729 Capsid-VNN 1,095 87 38
PF12264 Waikav_capsid_1 92 37 31
PF12944 HAV_VP 1,409 62 28
PF15414 DUF4621 37 7 5
PF16530 IHHNV_capsid 162 3 3
PF16903 Capsid_N 3,226 1,334 419
PF17800 NPL 3,297 1,919 778
CL0056 C_Lectin 130,084 80,467 33,076 PF00059 Lectin_C 50,885 33,305 16,577
PF00193 Xlink 6,261 3,270 912
PF01413 C4 3,092 1,646 476
PF03440 APT 340 79 22
PF03781 FGE-sulfatase 63,844 40,386 14,230
PF05473 UL45 285 146 82
PF05689 InvE_AD 3,043 553 182
PF05966 Chordopox_A33R 153 42 18
PF06482 Endostatin 1,842 1,063 411
PF07588 DUF1554 1,116 594 260
PF07979 Intimin_C 494 78 21
PF08391 Ly49 468 203 65
PF16825 DUF5075 240 126 62
CL0057 Met_repress 164,393 79,629 23,645 PF01340 MetJ 2,310 210 23
PF01402 RHH_1 32,933 16,896 6,515
PF02697 VAPB_antitox 1,704 1,252 482
PF03693 ParD_antitoxin 11,488 5,810 1,165
PF03869 Arc 7,470 3,677 1,759
PF04221 RelB 13,821 5,349 1,664
PF05509 TraY 1,508 590 228
PF05534 HicB 9,022 4,929 1,462
PF07181 VirC2 97 41 22
PF07362 CcdA 4,548 2,017 663
PF07704 PSK_trans_fac 3,072 1,728 436
PF07764 Omega_Repress 276 22 13
PF07878 RHH_5 1,584 1,077 573
PF08681 DUF1778 8,731 3,844 1,232
PF08870 DndE 1,440 865 164
PF08972 DUF1902 923 603 275
PF09274 ParG 836 361 188
PF09386 ParD 530 283 88
PF09957 VapB_antitoxin 6,249 3,733 854
PF10723 RepB-RCR_reg 1,163 224 88
PF10784 Plasmid_stab_B 1,402 188 71
PF10802 DUF2540 30 20 12
PF11020 DUF2610 178 81 48
PF11423 Repressor_Mnt 227 43 10
PF11903 ParD_like 4,453 1,911 336
PF12441 CopG_antitoxin 3,187 2,161 596
PF12651 RHH_3 1,964 954 539
PF13467 RHH_4 8,118 3,646 613
PF14384 BrnA_antitoxin 8,534 4,852 1,351
PF15919 HicB_lk_antitox 18,975 10,321 2,382
PF15970 HicB-like_2 461 229 46
PF16762 RHH_6 496 183 59
PF16777 RHH_7 775 42 23
PF17206 SeqA_N 2,567 579 60
PF17414 MatP_C 1,990 274 45
PF17723 RHH_8 1,362 710 193
PF18064 ParB_C 302 196 87
CL0058 Glyco_hydro_tim 939,268 458,097 116,619 PF00128 Alpha-amylase 200,777 84,277 13,225
PF00150 Cellulase 51,089 27,808 8,732
PF00232 Glyco_hydro_1 66,990 27,386 6,005
PF00331 Glyco_hydro_10 18,481 10,962 3,261
PF00332 Glyco_hydro_17 17,162 8,687 2,261
PF00704 Glyco_hydro_18 62,808 31,810 10,833
PF00728 Glyco_hydro_20 32,094 17,059 5,069
PF00933 Glyco_hydro_3 101,676 49,983 9,684
PF01055 Glyco_hydro_31 42,910 19,823 5,387
PF01120 Alpha_L_fucos 22,943 13,246 2,935
PF01183 Glyco_hydro_25 25,461 11,135 3,837
PF01229 Glyco_hydro_39 7,383 4,546 1,622
PF01301 Glyco_hydro_35 19,305 9,734 2,569
PF01373 Glyco_hydro_14 3,658 1,644 558
PF01630 Glyco_hydro_56 3,448 1,833 594
PF02055 Glyco_hydro_30 9,738 5,481 1,361
PF02057 Glyco_hydro_59 1,882 1,004 311
PF02065 Melibiase 17,141 8,678 2,144
PF02156 Glyco_hydro_26 8,939 5,500 1,920
PF02286 Dehydratase_LU 2,068 387 76
PF02324 Glyco_hydro_70 949 262 119
PF02446 Glyco_hydro_77 22,708 10,502 2,521
PF02449 Glyco_hydro_42 18,452 9,907 2,974
PF02638 GHL10 13,794 6,860 2,150
PF02836 Glyco_hydro_2_C 55,540 27,703 6,418
PF03198 Glyco_hydro_72 5,314 2,873 672
PF03537 Glyco_hydro_114 6,742 4,249 1,400
PF03644 Glyco_hydro_85 3,314 1,792 745
PF03659 Glyco_hydro_71 3,206 1,984 749
PF03662 Glyco_hydro_79n 2,655 1,353 451
PF05089 NAGLU 4,085 2,137 644
PF05691 Raffinose_syn 3,953 2,083 789
PF07555 NAGidase 4,907 2,407 811
PF07745 Glyco_hydro_53 5,916 3,061 946
PF08924 DUF1906 4,821 2,565 823
PF10566 Glyco_hydro_97 10,578 5,124 892
PF11308 Glyco_hydro_129 1,575 559 164
PF11790 Glyco_hydro_cc 5,845 3,768 1,655
PF12876 Cellulase-like 368 211 48
PF12891 Glyco_hydro_44 860 598 243
PF12905 Glyco_hydro_101 1,504 583 212
PF13199 Glyco_hydro_66 968 536 261
PF13200 DUF4015 4,150 2,573 921
PF13204 DUF4038 4,118 2,636 879
PF14307 Glyco_tran_WbsX 3,870 2,525 1,014
PF14488 DUF4434 2,092 862 277
PF14587 Glyco_hydr_30_2 3,016 1,724 453
PF14701 hDGE_amylase 2,625 1,344 382
PF14871 GHL6 1,847 1,343 463
PF14872 GHL5 250 168 29
PF14883 GHL13 2,802 715 189
PF14885 GHL15 978 744 421
PF16126 DUF4838 2,693 2,113 1,345
PF16141 DUF4849 1,406 445 159
PF16317 Glyco_hydro_99 1,881 1,056 508
PF16402 DUF5010 154 109 66
PF16499 Melibiase_2 13,722 7,874 1,840
PF18952 DUF5696 1,532 986 500
CL0059 6_Hairpin 305,674 156,858 42,572 PF00432 Prenyltrans 13,440 8,054 3,061
PF00723 Glyco_hydro_15 28,098 12,796 2,139
PF00759 Glyco_hydro_9 15,410 8,726 2,640
PF01122 Cobalamin_bind 928 574 231
PF01204 Trehalase 15,168 6,759 2,073
PF01270 Glyco_hydro_8 8,315 3,345 953
PF01532 Glyco_hydro_47 16,062 8,369 2,613
PF02011 Glyco_hydro_48 1,964 846 174
PF03200 Glyco_hydro_63 6,721 3,538 821
PF03632 Glyco_hydro_65m 14,809 7,218 1,364
PF03663 Glyco_hydro_76 11,752 6,246 1,583
PF04685 DUF608 4,615 2,536 850
PF05147 LANC_like 10,566 6,501 3,033
PF06202 GDE_C 12,786 6,895 1,719
PF06662 C5-epim_C 1,793 1,010 572
PF06824 Glyco_hydro_125 6,719 2,790 468
PF07221 GlcNAc_2-epim 17,482 8,037 1,866
PF07470 Glyco_hydro_88 23,467 11,310 2,348
PF07678 TED_complement 16,610 7,535 2,888
PF07944 Glyco_hydro_127 17,756 9,558 2,437
PF09492 Pec_lyase 2,398 1,526 463
PF10091 Glycoamylase 10,358 5,702 1,089
PF12899 Glyco_hydro_100 3,355 1,582 321
PF13243 SQHop_cyclase_C 13,995 7,165 1,816
PF13249 SQHop_cyclase_N 11,130 5,234 916
PF17167 Glyco_hydro_36 10,330 5,427 1,246
PF17389 Bac_rhamnosid6H 20,311 12,465 3,647
PF17652 Glyco_hydro81C 3,994 2,364 829
PF18566 Ldi 764 542 221
CL0060 DNA_clamp 56,343 22,282 6,759 PF00705 PCNA_N 6,021 2,737 836
PF00712 DNA_pol3_beta 37,443 12,914 2,913
PF02144 Rad1 2,340 1,235 472
PF02282 Herpes_UL42 310 40 23
PF02747 PCNA_C 5,559 2,528 740
PF02767 DNA_pol3_beta_2 38,954 13,905 3,306
PF02768 DNA_pol3_beta_3 37,703 13,093 3,055
PF02916 DNA_PPF 1,266 165 42
PF03325 Herpes_PAP 104 18 3
PF04005 Hus1 2,470 1,277 485
PF04139 Rad9 2,682 1,555 675
PF04929 Herpes_DNAp_acc 98 29 17
PF09116 gp45-slide_C 556 214 73
CL0061 PLP_aminotran 1,351,970 561,422 84,367 PF00155 Aminotran_1_2 466,412 186,807 29,093
PF00202 Aminotran_3 225,918 87,086 11,391
PF00266 Aminotran_5 221,758 99,827 14,878