EFI - Enzyme Similarity Tool

This web resource is supported by a Research Resource from the National Institute of General Medical Sciences (R24GM141196-01).
The tools are available without charge or license to both academic and commercial users.
RadicalSAM.org, our resource for investigating sequence-function space in the radical SAM superfamily, has been updated with sequences from the UniProt Release 2024_01 and InterPro Release 98 databases (January 24, 2024) !!

https://radicalsam.org

Neighborhood Connectivity

Uploaded Filename: 27106_IP91_IPR004184_UniRef90_NoFragments_Minlen650_AS120_full_ssn.xgmml.zip

Two node attributes were added to the input SSN: 1) Neighborhood Connectivity that quantitates the internode connections and 2) Neighborhood Connectivity Coloring that assigns a color based on the value of the NC.

The Data File Download tab provides the SSN with the nodes colored according to the value of the Neighborhood Connectivity Coloring.

The Neighborhood Connectivity Color Scale download provides the color scale in the SSN.

Submission Summary Table

Job Number27187
Input OptionNeighborhood Connectivity
Uploaded Filename27106_IP91_IPR004184_UniRef90_NoFragments_Minlen650_AS120_full_ssn.xgmml.zip
Database VersionUniProt: 2022-04 / InterPro: 91
Please cite your use of the EFI tools:

Rémi Zallot, Nils Oberg, and John A. Gerlt, The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways. Biochemistry 2019 58 (41), 4169-4182. https://doi.org/10.1021/acs.biochem.9b00735

Nils Oberg, Rémi Zallot, and John A. Gerlt, EFI-EST, EFI-GNT, and EFI-CGFP: Enzyme Function Initiative (EFI) Web Resource for Genomic Enzymology Tools. J Mol Biol 2023. https://doi.org/10.1016/j.jmb.2023.168018

Colored SSN

Each node in the submitted SSN has been colored by NC, and a Neighborhood Connectivity attribute has been added with the NC factor.

Supplementary Files
Neighborhood Connectivity Color Scale (PNG)
Neighborhood Connectivity Table

Click here to contact us for help, reporting issues, or suggestions.

Carl R. Woese Institute for Genomic Biology
University of Illinois at Urbana-Champaign
1206 W. Gregory Drive Urbana, IL 61801
efi@enzymefunction.org