EFI - Enzyme Similarity Tool

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Pfam Families

These data are sourced from the UniProt and EMBL-EBI InterPro databases.

Clan ID Short Name Size UniRef90 Size UniRef50 Size Pfam ID Short Name Size UniRef90 Size UniRef50 Size
CL0001 EGF 381,776 166,695 58,971 PF00008 EGF 108,135 48,932 17,525
PF00053 Laminin_EGF 49,937 23,106 6,149
PF00084 Sushi 68,871 32,345 12,435
PF00594 Gla 10,864 3,954 727
PF01414 DSL 8,276 3,193 1,049
PF04863 EGF_alliinase 721 370 107
PF06247 Plasmod_Pvs28 465 87 48
PF07645 EGF_CA 103,409 45,082 14,999
PF07699 Ephrin_rec_like 25,464 11,036 5,157
PF07974 EGF_2 28,909 11,576 4,538
PF09014 Sushi_2 1,172 459 90
PF09064 Tme5_EGF_like 660 413 119
PF09289 FOLN 4,904 1,186 197
PF09443 CFC 1,034 558 166
PF12661 hEGF 46,087 19,950 6,612
PF12662 cEGF 32,764 14,095 3,804
PF12946 EGF_MSP1_1 2,772 307 123
PF12947 EGF_3 28,556 12,370 4,412
PF14670 FXa_inhibition 48,916 18,645 4,799
PF18193 Fibrillin_U_N 2,174 989 91
PF18372 I-EGF_1 8,810 2,305 442
PF18720 EGF_Tenascin 5,967 2,711 633
PF20626 Sp38_C 1,101 437 78
PF21195 C8A_B_C6_EGF-like 3,234 1,155 135
PF21284 C7_FIM2_N 351 85 11
PF21286 CFAI_FIMAC_N 957 361 74
PF21364 FBN_EGF_st1 2,143 982 84
PF21700 DL-JAG_EGF-like 9,316 3,116 736
PF21795 JAG1-like_EGF2 526 173 65
CL0003 SAM 216,128 83,911 18,645 PF00536 SAM_1 96,323 37,110 9,269
PF01698 SAM_LFY 1,704 333 61
PF02198 SAM_PNT 14,255 3,953 1,217
PF02961 BAF 1,921 832 350
PF04904 NCD1 2,568 706 254
PF07647 SAM_2 64,034 25,802 6,357
PF09235 SAM_Ste50p 72 51 25
PF09597 IGR 1,965 1,084 335
PF13543 SAM_KSR1 875 408 117
PF13932 GIDA_C 38,607 17,530 1,513
PF18016 SAM_3 9,100 3,020 654
PF18017 SAM_4 1,534 724 301
PF18255 SAM_DrpA 708 95 11
PF18609 SAM_Exu 271 163 62
CL0004 Concanavalin 686,226 369,908 128,582 PF00054 Laminin_G_1 16,383 7,756 2,078
PF00139 Lectin_legB 16,599 9,493 3,390
PF00262 Calreticulin 12,281 4,815 1,165
PF00337 Gal-bind_lectin 18,670 8,879 3,276
PF00354 Pentaxin 12,650 6,068 1,889
PF00426 VP4_haemagglut 15,369 793 77
PF00457 Glyco_hydro_11 5,878 3,057 667
PF00622 SPRY 106,311 51,990 14,329
PF00629 MAM 34,255 15,260 5,952
PF00722 Glyco_hydro_16 57,693 33,461 10,652
PF00840 Glyco_hydro_7 9,406 3,336 633
PF01670 Glyco_hydro_12 6,188 3,235 945
PF01828 Peptidase_A4 3,621 2,289 966
PF02210 Laminin_G_2 63,876 27,153 6,455
PF02973 Sialidase 757 226 111
PF03388 Lectin_leg-like 8,424 3,651 1,076
PF03935 SKN1_KRE6_Sbg1 4,903 3,123 859
PF05592 Bac_rhamnosid 16,706 11,115 2,867
PF05735 TSP_C 8,955 2,457 478
PF06009 Laminin_II 4,909 2,723 394
PF06439 3keto-disac_hyd 45,076 33,317 8,697
PF06955 XET_C 10,604 4,445 742
PF07081 DUF1349 9,389 4,792 1,138
PF07177 Neuralized 6,650 2,733 1,027
PF07622 DUF1583 178 152 120
PF07675 Cleaved_Adhesin 2,252 1,861 1,272
PF07953 Toxin_R_bind_N 337 61 32
PF08244 Glyco_hydro_32C 27,329 13,394 3,152
PF08787 Alginate_lyase2 5,423 2,828 758
PF08978 Reoviridae_Vp9 40 14 9
PF09101 Exotox-A_bind 207 41 16
PF09206 ArabFuran-catal 2,486 1,399 307
PF09224 DUF1961 882 596 169
PF09264 Sial-lect-inser 103 42 27
PF10008 DUF2251 533 240 77
PF10287 YJL171C_Tos1_C 1,265 733 206
PF11476 TgMIC1 19 4 4
PF11958 DUF3472 2,170 1,419 481
PF12248 Methyltransf_FA 3,482 2,043 1,032
PF13385 Laminin_G_3 96,227 70,550 41,225
PF13765 PRY 52,084 27,737 7,189
PF14099 Polysacc_lyase 3,654 2,607 1,368
PF14299 PP2 8,111 4,765 1,943
PF15493 YrpD 146 63 40
PF16346 GH32_BT1760-like_C 467 205 51
PF16451 bCoV_S1_N 3,372 389 43
PF17689 Arabino_trans_N 3,335 1,375 170
PF17851 GH43_C2 22,794 12,643 2,295
PF17995 GH101_N 613 149 63
PF18239 HA1 7 4 3
PF18271 GH131_N 2,354 1,351 338
PF18483 Bact_lectin 4,106 2,874 1,842
PF19559 DUF6081 567 324 111
PF19763 DUF6250 1,068 591 165
PF20407 DUF1583_N 189 163 130
PF20562 DUF6772 408 198 28
PF20773 InhA-like_MAM 10,307 6,121 2,194
PF20842 Rax2_2 1,549 865 209
PF20843 Rax2_3 1,556 866 209
PF21209 Bac_rhamnosid-like_N 777 362 62
PF21294 Polysacc_lyase_14 2,747 2,117 1,010
PF21340 Polysacc_lyase-like 1,106 639 251
PF21708 Glyco_hydro_59_C 2,468 1,088 291
CL0005 Kazal 53,813 22,364 8,301 PF00050 Kazal_1 14,119 7,590 3,632
PF07648 Kazal_2 39,567 15,471 5,542
PF18434 Kazal_3 1,304 392 54
PF21287 CFAI_KAZAL 947 356 75
PF21288 C6_KAZAL 1,017 331 41
PF21330 C7_KAZAL 1,345 395 47
CL0007 KH 358,529 143,316 24,316 PF00013 KH_1 156,374 62,903 13,501
PF04025 RemA-like 8,032 3,696 563
PF07650 KH_2 93,479 33,868 3,434
PF09869 DUF2096 315 215 59
PF13083 KhpA-B_KH 32,132 14,948 2,499
PF13184 KH_5 45,842 17,692 2,040
PF14611 SLS 667 400 203
PF14955 MRP-S24 1,266 718 203
PF15985 KH_6 7,951 3,828 966
PF16005 MOEP19 845 420 184
PF17214 KH_7 3,318 1,503 200
PF17903 KH_8 5,669 2,265 423
PF17904 KH_9 5,356 1,685 246
PF17905 KH_10 94 58 35
PF20704 NucS_shadow 1,893 456 32
PF20777 SLS1_KH2 535 273 128
PF21482 GLD3_KH3 16 9 3
PF21718 DTX3L_KH-like 730 401 65
PF21800 KRR1-like_KH2 7,584 3,263 616
CL0010 SH3 1,953,529 868,691 225,678 PF00018 SH3_1 188,406 74,460 17,505
PF00385 Chromo 64,599 35,347 14,501
PF00467 KOW 91,493 35,247 4,727
PF00552 IN_DBD_C 67,044 6,711 889
PF00565 SNase 40,950 26,565 11,401
PF00567 TUDOR 24,141 12,098 5,126
PF00855 PWWP 40,281 16,910 5,126
PF00924 MS_channel_2nd 142,679 77,146 20,199
PF01157 Ribosomal_L21e 9,403 3,608 667
PF01245 Ribosomal_L19 46,496 17,676 1,885
PF01302 CAP_GLY 30,599 14,296 4,337
PF01393 Chromo_shadow 6,685 3,105 1,297
PF01423 LSM 65,424 24,614 6,716
PF01426 BAH 30,124 13,355 3,488
PF01777 Ribosomal_L27e 4,810 1,721 477
PF01845 CcdB 4,046 2,023 520
PF01929 Ribosomal_L14e 5,689 2,137 537
PF02170 PAZ 29,442 12,756 3,900
PF02211 NHase_beta_C 5,124 2,885 506
PF02237 BPL_C 31,353 17,536 4,888
PF02294 7kD_DNA_binding 99 19 15
PF02427 PSI_PsaE 1,956 913 123
PF02452 PemK_toxin 43,609 26,653 5,989
PF02513 Spin-Ssty 2,371 635 150
PF02559 CarD_TRCF_RID 62,403 27,368 4,862
PF02736 Myosin_N 27,577 10,507 1,468
PF02820 MBT 15,308 4,812 1,375
PF02941 FeThRed_A 1,302 647 176
PF03217 SlpA 3,099 1,532 828
PF03831 YjdM 17,095 6,827 296
PF03947 Ribosomal_L2_C 71,531 18,755 1,511
PF03983 SHD1 2,869 2,009 997
PF04023 FeoA 50,708 28,818 6,593
PF04153 NOT2_3_5_C 11,270 4,562 1,302
PF04319 NifZ 2,380 1,231 143
PF04397 LytTR 97,952 57,835 17,003
PF05641 Agenet 12,553 5,554 2,161
PF06003 SMN_Tudor 3,885 1,526 509
PF06004 DUF903 5,787 933 153
PF06107 DUF951 7,231 3,686 329
PF06257 VEG 4,502 1,521 250
PF06347 SH3_4 8,408 5,636 1,838
PF06372 Gemin6 992 423 146
PF06442 DHFR_2 111 43 24
PF06613 KorB_C 384 143 53
PF06701 MIB_HERC2 7,200 3,063 868
PF07039 SGF29_Tudor 3,746 1,824 665
PF07126 ZapC_C 2,081 526 86
PF07563 DUF1541 1,600 862 129
PF07653 SH3_2 82,956 33,338 8,408
PF07866 DUF1653 8,059 4,200 887
PF08141 SspH 2,438 1,220 201
PF08169 RBB1NT 2,547 1,221 235
PF08207 EFP_N 48,534 17,033 1,329
PF08239 SH3_3 57,214 36,040 18,560
PF08460 SH3_5 2,460 787 382
PF08605 Rad9_Rad53_bind 322 209 101
PF08810 KapB 1,151 542 56
PF08838 DUF1811 1,342 557 48
PF08940 DUF1918 3,236 1,917 302
PF08948 PRD1_P5_spike_N 13 5 4
PF09038 53-BP1_Tudor 1,336 583 149
PF09465 LBR_tudor 1,192 306 89
PF09629 YorP 45 9 5
PF09671 Spore_GerQ 1,573 826 147
PF09926 DUF2158 2,392 1,017 523
PF09953 DUF2187 1,710 545 144
PF10383 Clr2 1,407 802 284
PF10842 DUF2642 1,081 589 260
PF11061 Tsr0524-like 865 384 51
PF11095 Gemin7 1,011 633 267
PF11160 Hva1_TUDOR 6,825 4,141 616
PF11302 DUF3104 247 168 73
PF11347 CRR42-like 1,153 612 133
PF11515 Cul7 2,704 1,233 218
PF11607 DUF3247 362 176 46
PF11623 NdhS 1,124 461 63
PF11717 Tudor-knot 14,593 6,352 1,934
PF11910 NdhO 1,154 524 58
PF12073 DUF3553 2,082 1,412 275
PF12148 TTD 2,459 855 140
PF12208 DUF3601 174 81 42
PF12212 PAZ_2 6 5 4
PF12701 LSM14 7,873 3,154 919
PF12913 SH3_6 3,370 1,372 476
PF12914 SH3_7 1,986 439 165
PF13234 MTR4_beta-barrel 7,721 3,325 665
PF13457 GW 2,908 1,318 729
PF13861 FLgD_tudor 9,640 4,814 1,276
PF13958 ToxN_toxin 905 559 334
PF13973 DUF4222 1,768 517 137
PF14001 YdfZ 856 96 17
PF14061 Mtf2_C 2,602 646 165
PF14192 DUF4314 1,786 936 312
PF14438 SM-ATX 6,238 2,618 699
PF14563 DUF4444 354 262 15
PF14603 hSH3 2,384 962 217
PF14604 SH3_9 95,083 37,598 9,277
PF14627 DUF4453 108 79 45
PF15057 DUF4537 1,443 773 309
PF15505 Vexin 292 88 16
PF15997 DUF4772 1,022 396 141
PF16090 DUF4819 1,409 714 243
PF16277 DUF4926 3,470 2,365 674
PF16719 SAWADEE 2,158 1,114 483
PF16906 Ribosomal_L26 8,382 3,672 789
PF17136 ribosomal_L24 43,656 17,808 1,511
PF17209 Hfq 18,881 5,783 733
PF17375 DUF5397 179 116 37
PF17384 DUF150_C 30,829 14,857 2,849
PF17516 ProQ_C 2,329 489 53
PF17902 SH3_10 13,271 4,169 790
PF18103 SH3_11 176 19 4
PF18104 Tudor_2 7,495 2,868 393
PF18115 Tudor_3 2,383 1,160 380
PF18129 SH3_12 3,732 1,852 537
PF18300 DUF5604 1,258 574 101
PF18309 PAZ_3 82 44 14
PF18332 XRN1_D1 3,672 1,847 495
PF18334 XRN1_D2_D3 3,816 1,921 541
PF18335 SH3_13 13,706 6,721 1,377
PF18336 Tudor_FRX1 4,360 1,359 197
PF18337 Tudor_RapA 6,013 1,621 258
PF18339 Tudor_1_RapA 6,089 1,684 280
PF18340 TraI_2B 1,581 367 140
PF18341 PSA_CBD 59 20 12
PF18342 LytB_SH3 320 51 11
PF18343 SH3_14 498 55 12
PF18346 SH3_15 4,242 1,613 489
PF18347 DUF5606 3,733 2,316 370
PF18348 SH3_16 9,640 6,289 1,432
PF18349 PAZ_4 4 4 2
PF18350 SH3_17 53 19 2
PF18354 SH3_18 55 30 9
PF18355 DUF5607 0 1 1
PF18356 DUF5608 0 1 1
PF18357 DtxR 1,086 355 28
PF18358 Tudor_4 1,730 924 272
PF18359 Tudor_5 1,750 966 355
PF18380 GEN1_C 1,338 865 281
PF18597 SH3_19 1,493 769 67
PF18697 MLVIN_C 2,171 1,412 865
PF18704 Chromo_2 1,102 605 170
PF19023 DUF5749 138 98 35
PF19087 DUF5776 1,905 1,037 587
PF20297 MSSS 12,666 6,252 1,341
PF20866 MdcG_N 3,317 1,611 369
PF20884 MUM1-like_PWWP 1,151 531 147
PF20887 PWP3A-B_N 774 348 84
PF21094 Nup188_SH3-like 1,789 578 68
PF21193 NMD_SH3 4,119 1,593 319
PF21196 PcrA_UvrD_tudor 31,459 13,814 2,062
PF21409 Ski2_beta-barrel 135 91 8
PF21485 IF5A-like_N 9,965 4,126 808
PF21530 Pif1_2B_dom 16,185 11,344 6,035
PF21743 PTM_DIR17_Tudor 2,183 1,286 761
PF21744 BAHCC1-like_Tudor 2,345 1,250 288
CL0012 Histone 193,261 65,757 22,472 PF00125 Histone 103,821 25,152 8,637
PF00808 CBFD_NFYB_HMF 29,572 14,422 5,000
PF02269 TFIID-18kDa 6,685 2,808 882
PF02291 TFIID-31kDa 4,665 1,896 614
PF02969 TAF 5,189 2,139 787
PF03540 TFIID_30kDa 3,569 1,681 516
PF03847 TFIID_20kDa 4,426 2,166 850
PF04719 TAFII28 3,829 1,977 719
PF05236 TAF4 6,189 2,717 897
PF07524 Bromo_TP 8,797 3,970 1,399
PF09123 DUF1931 831 288 78
PF09415 CENP-X 2,339 1,440 554
PF15510 CENP-W 855 431 110
PF15511 CENP-T_C 9,253 3,088 1,159
PF15630 CENP-S 2,649 1,444 548
PF15715 PAF 866 481 153
PF17027 Bromo_TP_like 54 44 33
CL0013 Beta-lactamase 612,859 334,947 86,492 PF00144 Beta-lactamase 209,180 131,484 39,881
PF00768 Peptidase_S11 73,159 36,124 9,053
PF00905 Transpeptidase 237,420 119,978 24,571
PF02113 Peptidase_S13 27,829 16,613 5,326
PF04960 Glutaminase 21,906 8,546 1,271
PF13354 Beta-lactamase2 43,538 22,403 6,483
CL0014 Glutaminase_I 787,156 387,713 59,140 PF00117 GATase 300,410 134,062 14,113
PF01174 SNO 17,240 9,034 1,004
PF01965 DJ-1_PfpI 154,199 72,589 9,570
PF02016 Peptidase_S66 27,118 15,011 2,639
PF03575 Peptidase_S51 25,231 14,858 3,386
PF04204 HTS 13,301 5,457 506
PF06283 ThuA 32,269 20,402 4,040
PF07090 GATase1_like 6,688 3,835 1,445
PF07685 GATase_3 49,861 24,106 2,654
PF07722 Peptidase_C26 32,842 18,114 4,723
PF08532 Glyco_hydro_42M 17,476 10,372 2,440
PF09822 ABC_transp_aux 17,754 12,137 4,547
PF09825 BPL_N 4,193 2,543 1,003
PF13507 GATase_5 48,612 22,518 1,995
PF13709 DUF4159 12,504 8,324 1,672
PF14258 DUF4350 11,117 7,505 2,920
PF17124 ThiJ_like 2,347 1,245 195
PF17385 LBP_M 1,576 646 93
PF18011 Catalase_C 12,193 4,972 388
PF21455 PylD_N 277 189 84
CL0015 MFS 2,294,563 1,094,243 260,412 PF00083 Sugar_tr 319,840 142,581 37,600
PF00854 PTR2 70,247 32,009 7,068
PF01306 LacY_symp 3,423 902 230
PF01733 Nucleoside_tran 11,627 5,490 1,757
PF01770 Folate_carrier 5,129 2,499 833
PF02487 CLN3 4,402 2,518 913
PF03092 BT1 10,251 5,617 1,960
PF03137 OATP 16,599 7,206 2,719
PF03209 PUCC 4,348 2,694 476
PF03219 TLC 4,453 2,968 1,360
PF03825 Nuc_H_symport 10,163 4,226 708
PF04884 UVB_sens_prot 6,319 3,476 1,327
PF05631 MFS_5 4,664 2,225 871
PF05977 MFS_3 58,411 33,231 8,948
PF05978 UNC-93 11,538 5,546 1,885
PF06237 SLC52_ribofla_tr 3,436 1,651 624
PF06609 TRI12 4,910 3,034 1,072
PF06779 MFS_4 11,465 5,183 1,168
PF06813 Nodulin-like 8,179 4,061 1,175
PF06963 FPN1 4,737 2,456 983
PF07672 MFS_Mycoplasma 118 61 29
PF07690 MFS_1 1,641,896 786,347 180,362
PF11700 ATG22 23,993 13,623 2,359
PF12832 MFS_1_like 21,569 11,569 4,628
PF13000 Acatn 6,961 3,612 1,142
PF13347 MFS_2 57,157 27,386 7,912
PF18943 DUF5690 2,005 1,214 264
CL0016 PKinase 2,556,810 1,309,554 456,651 PF00069 Pkinase 1,476,213 755,025 282,767
PF00454 PI3_PI4_kinase 56,842 26,023 7,379
PF01163 RIO1 23,942 11,994 2,991
PF01504 PIP5K 28,452 11,982 3,624
PF01633 Choline_kinase 19,289 9,818 3,376
PF01636 APH 207,225 124,432 37,247
PF02816 Alpha_kinase 11,045 5,735 2,558
PF02958 EcKL 13,734 9,494 4,253
PF03109 ABC1 74,723 36,969 9,024
PF03770 IPK 13,578 6,308 2,306
PF03881 Fructosamin_kin 17,956 10,422 2,578
PF04183 IucA_IucC 15,483 7,016 1,213
PF04655 APH_6_hur 8,584 4,929 1,106
PF05445 Pox_ser-thr_kin 177 57 25
PF06090 Ins_P5_2-kin 4,189 2,200 1,049
PF06176 WaaY 1,719 302 180
PF06293 Kdo 23,032 11,453 4,197
PF06315 AceK_kinase 6,407 2,168 288
PF06702 Fam20C 5,109 1,950 530
PF06734 UL97 485 30 16
PF07387 Seadorna_VP7 63 38 21
PF07714 PK_Tyr_Ser-Thr 448,282 219,303 81,715
PF07804 HipA_C 27,177 16,062 3,770
PF07914 DUF1679 2,070 1,642 1,043
PF08757 CotH 20,892 16,199 8,691
PF09192 Act-Frag_cataly 897 399 168
PF10009 DUF2252 11,070 5,692 1,122
PF10140 YukC 1,319 473 213
PF10707 YrbL-PhoP_reg 1,874 865 398
PF12260 PIP49_C 6,555 1,848 583
PF12330 Haspin_kinase 12,708 6,040 2,421
PF13095 FTA2 1,009 656 315
PF13575 DUF4135 3,387 2,262 1,269
PF14531 Kinase-like 657 193 129
PF16474 KIND 4,230 2,207 529
PF17667 Pkinase_fungal 15,187 12,845 7,727
PF18101 Pan3_PK 4,073 1,783 503
PF18762 Kinase-PolyVal 533 380 168
PF19250 DUF5898 89 81 62
PF19974 TCAD9 656 559 383
PF20613 HipA_2 6,231 3,420 690
CL0018 bZIP 108,697 45,947 16,394 PF00170 bZIP_1 71,241 29,833 10,230
PF03131 bZIP_Maf 12,803 4,288 1,264
PF07716 bZIP_2 24,666 12,141 5,561
CL0020 TPR 3,129,136 1,672,494 661,932 PF00244 14-3-3 20,102 6,029 1,912
PF00514 Arm 70,516 24,621 7,224
PF00515 TPR_1 118,554 63,604 34,519
PF00613 PI3Ka 19,159 7,384 1,676
PF00637 Clathrin 20,396 7,072 1,898
PF00790 VHS 25,231 10,034 2,227
PF00806 PUF 22,890 11,463 4,042
PF00888 Cullin 30,770 12,701 4,418
PF01239 PPTA 10,928 5,840 2,043
PF01347 Vitellogenin_N 10,388 5,260 2,224
PF01365 RYDR_ITPR 13,155 8,179 1,124
PF01417 ENTH 14,784 6,488 1,823
PF01535 PPR 177,867 98,896 39,449
PF01602 Adaptin_N 48,786 20,257 4,359
PF01603 B56 16,674 6,031 1,375
PF01749 IBB 13,279 3,566 842
PF01816 LRV 1,581 1,159 597
PF01843 DIL 18,691 8,630 1,570
PF01851 PC_rep 10,903 3,611 713
PF02020 W2 19,290 7,501 1,710
PF02071 NSF 11 11 11
PF02184 HAT 3,990 1,471 281
PF02259 FAT 16,482 8,808 2,450
PF02847 MA3 22,785 10,073 2,676
PF02854 MIF4G 33,145 15,243 4,803
PF02985 HEAT 28,312 12,770 5,644
PF03081 Exo70_C 13,427 5,985 1,862
PF03097 BRO1 14,478 6,138 1,876
PF03130 HEAT_PBS 12,012 8,537 4,877
PF03224 V-ATPase_H_N 5,331 2,066 621
PF03377 TAL_effector 602 315 111
PF03378 CAS_CSE1 4,522 1,768 610
PF03635 Vps35 5,507 2,010 687
PF03704 BTAD 52,120 37,959 16,066
PF03810 IBN_N 44,521 15,728 3,898
PF03914 CBF 11,646 5,606 1,743
PF04048 Sec8_N 3,861 1,673 449
PF04049 ANAPC8 4,806 1,731 568
PF04050 Upf2 4,020 1,687 449
PF04054 Not1 6,537 2,877 720
PF04078 Rcd1 5,332 1,966 657
PF04090 Rrn11 1,090 707 305
PF04091 Sec15_C 6,705 2,327 533
PF04097 Nic96 4,543 1,806 654
PF04100 Vps53_N 4,969 2,055 622
PF04118 Dopey_N 4,990 2,341 579
PF04124 Dor1 3,911 2,015 706
PF04129 Vps52_CC 3,937 1,755 506
PF04136 COG3_N 4,160 1,784 561
PF04177 TAP42 3,973 2,131 730
PF04184 ST7 5,251 1,548 349
PF04190 GET4 3,989 1,730 535
PF04437 RINT1_TIP1 4,224 1,905 690
PF04733 Coatomer_E 4,883 2,216 824
PF04818 CID 24,221 10,857 3,378
PF04826 Arm_2 3,612 1,358 471
PF04840 Vps16_C 5,227 2,156 770
PF04869 Uso1_p115_head 4,677 2,073 517
PF04910 Tcf25 4,423 2,348 829
PF05004 IFRD 5,571 2,058 725
PF05282 AAR2 3,486 1,723 659
PF05327 RRN3 4,627 2,166 863
PF05470 eIF-3c_N 4,742 2,139 698
PF05484 LRV_FeS 690 435 52
PF05536 Neurochondrin 2,726 1,233 512
PF05804 KAP 3,209 1,237 535
PF05843 Suf 7,095 3,189 1,152
PF05918 API5 2,873 1,120 511
PF06041 DUF924 12,591 7,550 1,434
PF06046 Sec6 8,210 3,295 1,024
PF06060 Mesothelin 2,024 1,291 431
PF06148 COG2 3,954 1,794 622
PF06239 ECSIT_N 1,184 656 239
PF06248 Zw10_N 1,652 470 128
PF06292 MUN 17,370 8,216 1,340
PF06367 Drf_FH3 18,609 8,724 1,594
PF06371 Drf_GBD 18,877 8,875 1,623
PF06419 COG6_N 3,845 1,584 476
PF06552 TOM20_plant 1,887 1,091 462
PF06685 DUF1186 839 675 441
PF06920 DHR-2_Lobe_A 22,104 9,710 1,393
PF06957 COPI_C 5,697 1,961 495
PF07219 HemY_N 12,444 5,759 1,431
PF07393 Sec10_HB 6,174 2,534 774
PF07539 UTP20_N 3,950 2,283 831
PF07571 TAF6_C 5,074 2,143 740
PF07575 Nucleopor_Nup85 4,178 2,026 771
PF07651 ANTH 22,383 9,651 1,896
PF07719 TPR_2 69,917 45,399 29,248
PF07720 TPR_3 1,970 866 514
PF07721 TPR_4 8,793 6,840 5,176
PF07817 GLE1 3,906 1,963 838
PF07980 SusD_RagB 91,789 53,994 10,939
PF08144 CPL 3,614 1,678 463
PF08158 SDA1_HEAT 4,389 1,918 574
PF08161 RRP12_HEAT 4,580 2,073 610
PF08163 DNAPKcs_CC3 1,957 1,152 361
PF08166 PELP1_HEAT 642 256 56
PF08167 RIX1 3,000 1,604 611
PF08216 CTNNBL 4,192 1,839 573
PF08238 Sel1 103,235 60,809 31,833
PF08311 Mad3_BUB1_I 5,488 3,016 1,037
PF08314 Sec39 3,496 1,819 532
PF08318 COG4_m 4,382 1,809 579
PF08321 PPP5 6,416 2,653 504
PF08324 PUL 5,549 2,679 775
PF08389 Xpo1 21,026 7,493 2,188
PF08453 Peptidase_M9_N 2,899 989 256
PF08454 RIH_assoc 11,816 7,499 944
PF08506 Cse1 9,233 3,143 917
PF08514 STAG 7,536 2,710 726
PF08558 TRF 2,731 1,324 420
PF08568 Kinetochor_Ybp2 3,425 1,608 592
PF08569 Mo25 6,437 2,250 631
PF08579 RPM2 163 118 69
PF08609 Fes1 4,117 2,014 588
PF08623 TIP120 4,979 1,731 511
PF08631 SPO22 2,401 1,464 575
PF08700 VPS51_Exo84_N 10,461 4,948 1,666
PF08713 DNA_alkylation 26,974 16,609 3,765
PF08767 CRM1_C 6,215 1,870 540
PF08852 DUF1822 2,956 1,886 857
PF09088 MIF4G_like 4,032 1,633 439
PF09090 MIF4G_like_2 4,117 1,685 482
PF09127 Leuk-A4-hydro_C 9,625 4,477 824
PF09246 PHAT 207 96 43
PF09268 Clathrin-link 5,826 1,575 219
PF09295 ChAPs 3,008 1,519 726
PF09450 DUF2019 455 339 120
PF09477 Type_III_YscG 186 46 13
PF09613 HrpB1_HrpK 605 250 128
PF09759 Atx10homo_assoc 3,339 1,780 734
PF09763 Sec3_CC 5,120 2,275 528
PF09770 PAT1 3,488 1,418 320
PF09790 Hyccin 4,031 1,439 425
PF09797 NatB_MDM20 4,236 1,970 808
PF09976 TPR_21 19,124 10,881 4,404
PF09986 DUF2225 2,917 1,900 708
PF10037 MRP-S27 2,116 944 287
PF10189 Ints3_N 2,371 1,102 464
PF10191 COG7 2,823 1,259 635
PF10255 Paf67 5,322 1,396 408
PF10257 RAI16-like 6,671 2,794 729
PF10274 ParcG 3,672 1,736 562
PF10300 Iml2-TPR_39 9,225 3,823 1,279
PF10304 RTP1_C2 1,988 1,073 309
PF10345 Cohesin_load 3,866 1,807 640
PF10350 DUF2428 4,585 2,630 1,079
PF10363 RTP1_C1 2,839 1,664 618
PF10366 Vps39_1 5,691 2,386 720
PF10373 EST1_DNA_bind 10,133 4,725 1,731
PF10374 EST1 7,404 3,253 1,075
PF10392 COG5_N 3,538 1,521 435
PF10474 Syndetin_C 2,999 1,089 412
PF10475 Vps54_N 5,205 2,062 731
PF10487 Nup188_N 2,337 974 278
PF10508 Proteasom_PSMB 2,480 1,058 474
PF10516 SHNi-TPR 3,613 1,745 591
PF10579 Rapsyn_N 1,361 346 123
PF10602 RPN7 9,548 3,265 951
PF10858 DUF2659 56 15 10
PF10952 DUF2753 306 93 26
PF11107 FANCF 917 523 184
PF11229 Focadhesin 1,310 590 149
PF11510 FA_FANCE 1,069 493 163
PF11698 V-ATPase_H_C 4,801 1,750 424
PF11701 UNC45-central 4,469 1,637 380
PF11791 Aconitase_B_N 12,353 2,982 189
PF11817 Foie-gras_1 4,948 2,085 713
PF11841 ELMO_ARM 5,969 1,889 335
PF11846 Wzy_C_2 3,298 1,849 698
PF11865 DUF3385 4,598 2,023 526
PF11894 Nup192 4,869 2,201 850
PF11935 SYMPK_PTA1_N 4,379 2,089 589
PF11988 Dsl1_N 67 49 27
PF11989 Dsl1_C 434 331 151
PF12022 COG2_C 3,128 1,424 570
PF12031 BAF250_C 5,653 2,330 430
PF12243 CTK3 1,469 739 227
PF12331 Rad26-like_helical_rpts 941 446 119
PF12348 CLASP_N 16,190 9,894 1,983
PF12372 Htt_N-HEAT 2,171 1,135 392
PF12460 MMS19_C 4,545 1,952 568
PF12530 DUF3730 2,114 1,009 361
PF12569 NatA_aux_su 6,543 2,463 744
PF12583 TPPII_C 1,932 585 177
PF12688 TPR_5 3,947 2,342 693
PF12717 Cnd1 7,042 3,705 1,296
PF12719 Cnd3 4,211 2,038 759
PF12741 SusD-like 4,546 2,116 515
PF12753 Nro1 265 191 76
PF12755 Vac14_Fab1_bd 5,736 2,359 653
PF12765 Cohesin_HEAT 5,151 2,553 1,008
PF12771 SusD-like_2 15,430 10,839 2,165
PF12783 Sec7-like_HUS 18,398 7,803 1,725
PF12830 Nipped-B_C 4,767 2,391 793
PF12854 PPR_1 46,438 25,794 10,306
PF12862 ANAPC5 5,597 3,225 1,995
PF12895 ANAPC3 24,898 13,143 7,026
PF12922 Cnd1_N 3,628 1,764 393
PF12968 DUF3856 60 48 11
PF13041 PPR_2 174,562 95,513 35,089
PF13174 TPR_6 77,072 50,994 28,970
PF13176 TPR_7 37,720 23,769 15,578
PF13181 TPR_8 297,558 181,414 101,227
PF13251 DUF4042 2,488 1,117 417
PF13281 MAP3K_TRAF_bd 4,402 2,021 358
PF13371 TPR_9 10,459 5,511 2,501
PF13374 TPR_10 82,300 56,485 34,604
PF13414 TPR_11 95,810 63,830 36,779
PF13424 TPR_12 215,971 144,695 81,732
PF13428 TPR_14 10,811 7,378 5,185
PF13429 TPR_15 5,417 3,584 2,230
PF13431 TPR_17 16,662 11,773 8,530
PF13432 TPR_16 332,377 217,771 114,135
PF13512 TPR_18 505 172 112
PF13513 HEAT_EZ 22,835 8,310 2,314
PF13525 YfiO 35,404 21,058 6,972
PF13646 HEAT_2 101,958 69,548 34,687
PF13812 PPR_3 44,024 26,530 14,075
PF13838 Clathrin_H_link 7,854 2,228 428
PF14322 SusD-like_3 87,561 50,874 9,949
PF14559 TPR_19 224,768 144,541 77,131
PF14561 TPR_20 19,537 9,024 1,460
PF14674 FANCI_S1-cap 933 280 27
PF14675 FANCI_S1 2,094 898 311
PF14676 FANCI_S2 2,165 938 326
PF14677 FANCI_S3 1,576 608 161
PF14678 FANCI_S4 2,263 997 385
PF14679 FANCI_HD1 1,839 757 224
PF14680 FANCI_HD2 2,257 997 352
PF14718 SLT_L 7,794 3,025 764
PF14763 HPS3_C 1,385 473 136
PF14764 SPG48 1,617 558 159
PF14852 Fis1_TPR_N 3,298 1,429 328
PF14853 Fis1_TPR_C 4,036 1,876 624
PF14863 Alkyl_sulf_dimr 10,501 5,539 1,003
PF14906 DUF4495 1,169 487 198
PF14929 TAF1_subA 1,675 743 344
PF14938 SNAP 11,748 5,429 2,425
PF15278 Sec3_C_2 3 4 3
PF15469 Sec5 5,192 2,437 784
PF15787 DUF4704 9,847 5,786 1,211
PF16186 Arm_3 13,856 3,657 846
PF16213 DCB 13,653 5,817 1,299
PF16399 Aquarius_N_1st 3,916 1,684 451
PF16415 CNOT1_CAF1_bind 5,686 2,973 797
PF16416 GUN4_N 642 313 33
PF16417 CNOT1_TTP_bind 5,307 2,721 628
PF16418 CNOT1_HEAT 4,875 2,461 508
PF16419 CNOT1_HEAT_N 138 93 26
PF16528 Exo84_C 4,379 1,842 486
PF16782 SIL1 544 317 151
PF16804 DUF5071 696 525 298
PF16811 TAtT 2,714 2,210 913
PF16854 VPS53_C 4,020 1,528 374
PF16918 PknG_TPR 3,765 2,003 366
PF16997 Wap1 54 43 28
PF17004 SRP_TPR_like 3,367 1,303 371
PF17127 DUF5106 2,111 1,394 591
PF17177 PPR_long 13,191 7,554 3,731
PF17432 DUF3458_C 15,549 7,163 979
PF17781 RPN1_RPN2_N 6,098 1,837 471
PF17826 DUF5588 748 392 131
PF17874 TPR_MalT 31,420 20,721 12,241
PF18028 Zmiz1_N 1,416 401 128
PF18055 RPN6_N 4,565 1,378 322
PF18071 HMW1C_N 506 251 54
PF18378 Nup188_C 1,201 589 177
PF18381 YcaO_C 4,944 1,157 93
PF18391 CHIP_TPR_N 1,543 585 175
PF18529 MIX 53 12 5
PF18581 SYCP2_ARLD 855 475 148
PF18710 ComR_TPR 840 224 95
PF18768 RNPP_C 1,846 670 320
PF18770 Arm_vescicular 2,482 959 167
PF18773 Importin_rep 1,933 668 156
PF18777 CRM1_repeat 5,030 1,427 249
PF18786 Importin_rep_2 1,427 326 28
PF18787 CRM1_repeat_3 5,363 1,519 288
PF18794 HSM3_C 117 84 56
PF18795 HSM3_N 311 167 77
PF18797 APC_rep 2,545 987 205
PF18806 Importin_rep_3 2,556 896 273
PF18808 Importin_rep_4 4,806 1,777 500
PF18816 Importin_rep_5 2,088 659 106
PF18817 HEAT_UF 41 25 2
PF18829 Importin_rep_6 4,692 1,626 420
PF18833 TPR_22 1,374 684 142
PF18944 DUF5691 2,933 1,721 596
PF19189 Mtf2 1,484 943 503
PF19273 Exportin-5 4,443 1,917 689
PF19282 Exportin-T 3,842 1,563 503
PF19424 UNC80 2,347 1,214 393
PF19427 Insc_C 1,409 496 196
PF19440 TTC7_N 3,395 1,203 287
PF19704 DNAPKcs_CC5 2,099 1,240 412
PF19867 DUF6340 1,389 903 420
PF19904 DUF6377 3,027 1,329 477
PF19964 EAD11 843 767 641
PF20023 WSLR 1,256 417 98
PF20052 GAP1-C 457 263 103
PF20103 DUF6493 1,884 1,197 477
PF20168 PDS5 11,876 5,018 2,049
PF20206 Tra1_ring 5,177 3,047 945
PF20210 Laa1_Sip1_HTR5 5,721 2,922 541
PF20225 DUF6584 712 407 140
PF20262 UNC80_C 2,701 1,452 492
PF20308 TPR-S 1,853 1,521 765
PF20416 UTP20_C 3,796 2,189 739
PF20421 DHR-2_Lobe_C 22,705 9,859 1,321
PF20425 Neurobeachin 5,924 3,439 459
PF20431 E_motif 66,981 35,045 9,359
PF20468 HPS6_C 758 209 52
PF20500 DNA-PKcs_N 2,013 1,198 414
PF20502 DNAPKcs_CC1-2 1,951 1,161 385
PF20518 Apc1_MidN 2,520 1,258 341
PF20649 COG5_C 3,700 1,589 478
PF20651 EXOC6_Sec15_N 6,545 2,191 457
PF20652 Sec8_C 3,087 1,294 319
PF20653 COG6_C 4,240 1,823 631
PF20654 Sec3_C-term 5,292 2,391 520
PF20655 Vps52_C 4,102 1,838 569
PF20662 COG4_C 4,236 1,706 529
PF20663 COG4_N 4,004 1,566 449
PF20665 Zw10_middle 2,574 995 378
PF20666 ZW10_C 2,644 1,064 454
PF20667 Sec10_N 4,138 1,398 352
PF20669 Exo70_N 9,639 3,766 803
PF20671 COG3_C 4,451 1,985 708
PF20867 UVSSA_N 1,837 962 336
PF20925 Htt_bridge 1,609 751 179
PF20926 Htt_N-HEAT_1 2,008 979 303
PF20927 Htt_C-HEAT 2,188 1,039 340
PF20998 Nol11_C 1,320 491 144
PF21033 RMD1-3 5,766 2,905 1,057
PF21035 CCDC138_C 1,188 438 135
PF21040 CEP104-like_TOG 10,401 6,490 1,116
PF21041 XMAP215_CLASP_TOG 12,320 7,600 1,160
PF21044 CIP2A_N 1,368 494 193
PF21045 INT10 1,951 502 189
PF21047 Maestro_HEAT 4,771 2,338 692
PF21049 CFA69_ARM_rpt 1,607 813 346
PF21050 ARMC9_ARM 2,072 850 302
PF21052 EFR3_ARM 5,717 1,625 323
PF21055 ZSWIM4-8_C 4,820 1,871 275
PF21058 Stereocilin 656 433 134
PF21071 LARP1_HEAT 4,829 2,122 618
PF21072 EFR3 1,546 855 264
PF21093 Nup188_N-subdom_III 2,927 1,299 371
PF21119 RYDR_Jsol 5,694 3,687 416
PF21170 FAN1_TPR 3,370 1,704 559
PF21232 Yme1-like_N 1,253 535 76
PF21245 PI4KB-PIK1_PIK 3,887 1,728 416
PF21246 Usp38-like_N 1,867 567 150
PF21259 Rgg_C 5,456 1,721 933
PF21289 EDC4_C 3,117 1,600 433
PF21325 SHPRH_helical-1st 1,940 980 301
PF21505 RPN2_N 4,542 1,875 426
PF21545 T7SS_EccA1_N 3,078 1,019 218
PF21547 TTI1 3,429 1,815 671
PF21581 SCD 8,232 2,906 763
PF21587 AP5B1_N 390 169 33
PF21588 AP5B1_middle 912 473 168
PF21603 Bdbt-like_TPR 109 69 19
PF21719 MIOS_a-sol 2,968 1,307 480
PF21810 DUF6880 1,898 1,278 515
CL0021 OB 2,354,273 1,001,482 175,468 PF00164 Ribosom_S12_S23 67,307 11,359 1,309
PF00181 Ribosomal_L2 69,222 17,637 1,206
PF00252 Ribosomal_L16 72,034 16,973 1,634
PF00313 CSD 131,535 44,905 7,237
PF00366 Ribosomal_S17 53,340 20,641 2,509
PF00436 SSB 88,947 44,202 9,144
PF00575 S1 236,187 97,585 15,293
PF00900 Ribosomal_S4e 9,091 3,593 959
PF01132 EFP 47,770 16,508 1,253
PF01176 eIF-1a 62,227 13,251 1,672
PF01200 Ribosomal_S28e 6,655 2,319 524
PF01287 eIF-5a 8,768 3,232 717
PF01330 RuvA_N 42,910 21,055 2,988
PF01336 tRNA_anti-codon 207,435 93,570 12,172
PF01588 tRNA_bind 96,582 46,054 6,035
PF01796 OB_aCoA_assoc 33,774 20,753 4,164
PF01938 TRAM 80,852 39,296 6,295
PF01957 NfeD 41,042 24,613 6,653
PF02303 Phage_DNA_bind 407 252 107
PF02721 DUF223 5,287 3,742 2,343
PF02760 HIN 827 338 165
PF02765 POT1 3,847 2,103 976
PF03100 CcmE 19,626 10,468 1,732
PF03120 DNA_ligase_OB 51,886 26,279 2,949
PF03319 EutN_CcmL 11,073 6,291 826
PF03459 TOBE 42,879 20,239 3,165
PF03870 RNA_pol_Rpb8 4,042 1,516 450
PF03919 mRNA_cap_C 4,602 2,134 667
PF04057 Rep-A_N 5,176 2,314 784
PF04076 BOF 5,311 1,692 533
PF04679 DNA_ligase_A_C 49,470 27,071 4,042
PF04717 Phage_base_V 37,216 18,747 5,369
PF06075 DUF936 2,277 1,119 310
PF06125 DUF961 2,463 304 93
PF06714 Gp5_OB 881 266 150
PF07076 DUF1344 1,680 590 186
PF07290 YqiJ_OB 2,486 898 198
PF07404 TEBP_beta 25 18 13
PF07497 Rho_RNA_bind 39,614 14,749 1,319
PF07717 OB_NTP_bind 61,793 25,047 5,008
PF08206 OB_RNB 27,401 11,752 1,940
PF08292 RNA_pol_Rbc25 3,834 1,679 515
PF08402 TOBE_2 127,856 56,331 6,887
PF08418 Pol_alpha_B_N 2,819 1,365 389
PF08585 RMI1_N_C 5,805 3,064 1,310
PF08646 Rep_fac-A_C 12,336 6,968 3,331
PF08661 Rep_fac-A_3 3,523 1,860 665
PF08804 gp32 1,493 611 244
PF09103 BRCA-2_OB1 2,552 1,533 725
PF09104 BRCA-2_OB3 1,209 721 253
PF09285 Elong-fact-P_C 48,491 16,999 1,306
PF09883 DUF2110 872 448 107
PF10246 MRP-S35 1,317 720 264
PF10341 TPP1 905 512 288
PF10447 EXOSC1 3,642 1,637 391
PF10451 Stn1 1,678 944 362
PF10991 Enc34_ssDNA-bd 2,811 1,200 419
PF11325 DUF3127 5,167 2,889 485
PF11506 DUF3217 16 9 6
PF11604 CusF_Ec 11,510 6,124 1,631
PF11736 DUF3299 6,769 3,205 1,050
PF11967 RecO_N 42,119 22,449 6,029
PF12658 Ten1 760 477 153
PF12667 NigD_N 1,641 584 196
PF12857 TOBE_3 7,424 2,285 161
PF12869 tRNA_anti-like 2,374 1,917 1,178
PF13114 RecO_N_2 1,009 243 38
PF13509 S1_2 11,685 5,066 664
PF13742 tRNA_anti_2 40,874 21,203 3,995
PF14444 S1-like 2,516 921 275
PF14481 Fimbrial_PilY2 45 24 18
PF14743 DNA_ligase_OB_2 4,825 2,884 839
PF15072 HROB 2,118 1,307 693
PF15490 Ten1_2 1,486 759 328
PF15793 SHLD2_C 751 316 93
PF16099 RMI1_C 1,637 817 329
PF16100 RMI2 1,226 657 246
PF16450 Prot_ATP_ID_OB_C 29,276 6,942 1,039
PF16669 TTC5_OB 1,501 668 260
PF16686 POT1PC 2,569 1,422 667
PF16745 RsgA_N 12,135 6,328 721
PF16773 Phage_SSB 303 17 7
PF16853 CDC13_N 56 42 27
PF16900 REPA_OB_2 7,683 3,965 1,771
PF16992 RNA_pol_RpbG 192 133 78
PF17092 PCB_OB 16,825 7,269 789
PF17185 NlpE_C 2,074 689 295
PF17191 RecG_wedge 39,219 19,829 3,306
PF17207 MCM_OB 37,242 13,420 3,305
PF17215 Rrp44_S1 4,371 1,524 281
PF17216 Rrp44_CSD1 6,333 2,438 613
PF17244 CDC24_OB3 679 373 173
PF17245 CDC24_OB2 550 282 110
PF17246 CDC24_OB1 540 296 126
PF17746 SfsA_N 13,161 7,243 1,120
PF17758 Prot_ATP_ID_OB_N 5,655 1,549 162
PF17768 RecJ_OB 39,175 20,577 4,437
PF17845 FbpC_C_terminal 39 9 2
PF17847 GlcV_C_terminal 67 27 10
PF17849 OB_Dis3 9,842 4,145 1,155
PF17850 CysA_C_terminal 3,160 1,193 150
PF17875 RPA43_OB 2,580 1,433 518
PF17876 CSD2 30,097 13,982 2,105
PF17877 Dis3l2_C_term 3,066 1,414 395
PF17878 ssDBP 67 31 12
PF17879 DNA_ligase_C 392 131 19
PF17912 OB_MalK 52,481 20,371 1,545
PF18018 DNA_pol_D_N 4,049 1,960 592
PF18233 Cdc13_OB4_dimer 52 39 25
PF18313 TLP1_add_C 3,988 2,183 363
PF18330 Lig_C 669 379 79
PF18352 Gp138_N 2,852 1,084 437
PF18543 ID 166 130 32
PF18614 RNase_II_C_S1 4,199 2,679 296
PF18691 Cdc13_OB2 30 18 12
PF18693 TRAM_2 28,821 13,014 1,534
PF18914 DUF5666 5,956 4,383 2,714
PF19913 WCOB 1,442 506 129
PF20093 DUF6484 986 562 183
PF21005 MCEL_GT_OB 183 35 4
PF21189 PHA02142 1,278 756 260
PF21191 CvfB_1st 3,378 1,109 104
PF21192 NMD3_OB 4,199 1,646 366
PF21236 PRS7_OB 4,045 797 174
PF21262 RRP40_S1 3,865 1,906 543
PF21265 SBB_T7 585 220 124
PF21266 RRP4_S1 5,010 2,314 560
PF21318 BRCA2DBD_OB2 1,011 584 154
PF21430 DTP-pb9_B-dom 226 24 8
PF21473 Ssb-like_OB 4,175 2,296 771
PF21474 DNApolII_N 4,325 924 85
PF21543 CvfB_2nd 4,208 1,482 134
PF21579 PabTrmU54_TRAM_dom 93 54 2
PF21634 MOV-10_beta-barrel 4,196 2,251 680
PF21669 SHLD2_OB1 920 352 60
PF21710 Spt6_S1 2,295 978 225
CL0022 LRR 680,920 355,635 157,657 PF00560 LRR_1 231,597 129,986 55,415
PF01030 Recep_L_domain 16,178 7,474 2,381
PF03382 DUF285 10,333 8,263 5,888
PF05725 FNIP 3,017 2,577 1,755
PF07723 LRR_2 6,369 4,028 2,052
PF07725 LRR_3 5,745 3,718 1,792
PF11921 DUF3439 1,150 760 59
PF12468 TTSSLRR 1,271 114 67
PF12799 LRR_4 50,546 28,591 16,463
PF13306 LRR_5 39,867 26,400 19,401
PF13516 LRR_6 128,245 70,852 34,198
PF13855 LRR_8 363,201 173,919 67,512
PF14580 LRR_9 30,366 13,795 4,533
PF18779 LRR_RI_capping 550 145 33
PF18791 Transp_inhibit 2,897 1,115 196
PF18805 LRR_10 233 82 22
PF18831 LRR_11 190 67 4
PF18837 LRR_12 1,203 234 35
PF19729 FBXL18_LRR 1,091 266 112
PF20919 DHU1_N 569 241 68
CL0023 P-loop_NTPase 12,756,207 6,071,527 1,345,749 PF00004 AAA 604,784 263,700 51,508
PF00005 ABC_tran 3,167,076 1,494,113 219,869
PF00006 ATP-synt_ab 250,175 70,705 5,552
PF00009 GTP_EFTU 507,912 162,204 20,968
PF00025 Arf 69,667 24,668 7,661
PF00063 Myosin_head 103,261 44,129 10,350
PF00071 Ras 274,130 97,550 29,923
PF00142 Fer4_NifH 53,090 10,087 840
PF00154 RecA 72,000 20,483 2,378
PF00158 Sigma54_activat 262,228 137,590 28,320
PF00176 SNF2-rel_dom 190,002 100,850 30,251
PF00225 Kinesin 133,841 65,043 20,575
PF00265 TK 26,976 12,104 1,532
PF00270 DEAD 698,700 332,279 70,257
PF00271 Helicase_C 961,077 462,279 99,343
PF00308 Bac_DnaA 60,358 26,841 5,128
PF00350 Dynamin_N 76,681 35,019 10,949
PF00406 ADK 82,630 38,535 7,529
PF00437 T2SSE 175,431 91,287 15,127
PF00448 SRP54 115,165 50,345 6,957
PF00485 PRK 63,438 26,693 4,887
PF00488 MutS_V 94,762 48,747 11,170
PF00493 MCM 39,398 14,987 4,138
PF00503 G-alpha 35,620 12,322 3,754
PF00519 PPV_E1_C 3,431 898 223
PF00580 UvrD-helicase 171,009 89,476 25,691
PF00625 Guanylate_kin 106,062 45,907 7,149
PF00685 Sulfotransfer_1 62,948 33,186 14,634
PF00693 Herpes_TK 1,233 127 61
PF00709 Adenylsucc_synt 56,590 21,624 2,819
PF00735 Septin 36,518 10,532 2,581
PF00910 RNA_helicase 24,224 5,239 2,813
PF00931 NB-ARC 144,906 97,489 42,352
PF01057 Parvo_NS1 5,398 1,229 683
PF01078 Mg_chelatase 53,854 29,035 3,648
PF01121 CoaE 49,435 29,108 6,963
PF01202 SKI 64,398 34,540 8,406
PF01268 FTHFS 33,248 13,986 1,465
PF01443 Viral_helicase1 16,221 4,181 1,823
PF01580 FtsK_SpoIIIE 78,243 42,364 8,611
PF01583 APS_kinase 38,365 19,041 2,900
PF01591 6PF2K 16,892 5,718 1,129
PF01637 ATPase_2 12,539 7,999 2,834
PF01656 CbiA 107,866 55,453 11,834
PF01695 IstB_IS21 49,818 23,730 7,943
PF01712 dNK 25,649 12,342 2,319
PF01715 IPPT 56,165 32,695 6,263
PF01745 IPT 884 615 450
PF01926 MMR_HSR1 401,429 185,185 30,401
PF01935 DUF87 31,533 19,374 5,823
PF02223 Thymidylate_kin 54,310 31,353 6,439
PF02224 Cytidylate_kin 41,603 22,625 3,220
PF02263 GBP 14,347 6,509 2,733
PF02283 CobU 22,617 12,422 2,063
PF02367 TsaE 44,375 26,253 5,768
PF02374 ArsA_ATPase 29,331 14,082 2,832
PF02399 Herpes_ori_bp 1,336 778 441
PF02421 FeoB_N 34,923 19,041 2,621
PF02456 Adeno_IVa2 767 207 80
PF02463 SMC_N 142,219 73,369 17,992
PF02492 cobW 94,331 42,273 6,345
PF02499 DNA_pack_C 816 154 44
PF02500 DNA_pack_N 534 104 35
PF02534 T4SS-DNA_transf 26,239 11,105 4,026
PF02562 PhoH 61,355 24,616 2,151
PF02572 CobA_CobO_BtuR 25,129 11,193 1,342
PF02606 LpxK 26,895 16,021 4,558
PF02689 Herpes_Helicase 1,719 491 320
PF02702 KdpD 17,607 7,115 878
PF02841 GBP_C 8,900 3,355 1,022
PF03028 Dynein_heavy 25,832 14,390 3,616
PF03029 ATP_bind_1 31,608 11,393 1,855
PF03192 DUF257 599 400 161
PF03193 RsgA_GTPase 41,027 20,733 3,226
PF03205 MobB 15,218 8,697 2,109
PF03215 Rad17 4,405 2,419 1,045
PF03237 Terminase_6N 22,717 11,496 3,534
PF03266 NTPase_1 6,527 4,226 1,884
PF03308 MeaB 32,981 18,926 2,486
PF03354 TerL_ATPase 13,196 5,983 1,395
PF03567 Sulfotransfer_2 27,296 14,519 7,376
PF03618 Kinase-PPPase 18,695 7,145 931
PF03668 ATP_bind_2 29,713 13,284 1,724
PF03796 DnaB_C 65,339 28,923 7,497
PF03846 SulA 3,466 1,085 284
PF03969 AFG1_ATPase 27,177 12,002 2,165
PF03976 PPK2 38,812 21,024 1,829
PF04257 Exonuc_V_gamma 11,175 5,084 1,695
PF04275 P-mevalo_kinase 2,038 1,174 331
PF04310 MukB 2,885 401 103
PF04317 DUF463 6,193 2,156 315
PF04466 Terminase_3 7,638 4,168 1,381
PF04548 AIG1 25,192 17,014 7,884
PF04665 Pox_A32 1,973 702 358
PF04670 Gtr1_RagA 9,251 3,500 1,050
PF04851 ResIII 157,465 76,997 17,566
PF05049 IIGP 4,435 3,066 1,333
PF05127 Helicase_RecD 9,563 4,170 1,135
PF05179 CDC73_C 4,043 1,747 560
PF05272 VapE-like_dom 9,204 3,731 1,726
PF05496 RuvB_N 48,430 19,618 1,362
PF05609 LAP1_C 2,122 978 290
PF05621 TniB 5,830 3,255 1,427
PF05625 PAXNEB 4,099 2,109 689
PF05673 DUF815 13,080 6,139 712
PF05707 Zot 3,855 2,659 1,238
PF05729 NACHT 75,730 51,796 23,862
PF05763 DUF835 2,221 1,595 760
PF05783 DLIC 6,717 2,436 778
PF05872 HerA_C 17,028 8,156 986
PF05876 GpA_ATPase 8,153 3,994 1,407
PF05879 RHD3_GTPase 4,072 2,077 761
PF05894 Podovirus_Gp16 306 241 138
PF05970 PIF1 32,885 22,768 11,461
PF06048 DUF927 4,938 2,794 1,469
PF06068 TIP49 9,316 2,897 729
PF06144 DNA_pol3_delta 37,675 18,977 5,913
PF06309 Torsin 5,303 2,175 583
PF06414 Zeta_toxin 9,502 5,882 2,487
PF06418 CTP_synth_N 54,952 20,531 1,505
PF06431 Polyoma_lg_T_C 2,453 251 98
PF06564 CBP_BcsQ 4,566 2,031 803
PF06733 DEAD_2 31,427 14,665 4,338
PF06745 ATPase 25,953 15,015 4,444
PF06858 NOG1 5,928 2,345 473
PF06911 Senescence 4,943 2,259 790
PF06990 Gal-3-0_sulfotr 5,446 2,971 1,420
PF07015 VirC1 2,274 1,065 309
PF07034 ORC3_N 3,902 1,876 705
PF07088 GvpD_P-loop 485 324 173
PF07517 SecA_DEAD 57,899 27,424 4,051
PF07652 Flavi_DEAD 37,744 3,404 311
PF07693 KAP_NTPase 16,600 10,801 5,899
PF07724 AAA_2 197,498 73,654 8,547
PF07726 AAA_3 75,342 37,427 2,674
PF07728 AAA_5 75,042 37,611 10,085
PF07755 DUF1611 6,431 3,959 448
PF07931 CPT 3,388 2,350 659
PF07999 RHSP 2,454 1,581 453
PF08245 Mur_ligase_M 268,512 141,635 25,687
PF08298 AAA_PrkA 11,640 3,051 427
PF08303 tRNA_lig_kinase 1,704 969 243
PF08351 TmcA_N 8,321 3,561 862
PF08423 Rad51 25,237 11,617 3,601
PF08433 KTI12 4,862 2,800 1,031
PF08438 YGR210-like_G4 5,298 2,574 322
PF08477 Roc 13,507 7,742 4,054
PF08903 DUF1846 4,772 2,118 150
PF09037 Sulphotransf 2,075 1,250 635
PF09140 MipZ 4,140 2,125 481
PF09439 SRPRB 4,030 2,026 669
PF09547 SpoIVA_ATPase 4,209 1,693 128
PF09711 Cas_Csn2 870 452 274
PF09807 ELP6 2,339 1,241 433
PF09818 ABC_ATPase 3,951 2,309 482
PF09820 AAA-ATPase_like 17,264 10,183 3,582
PF09848 SLFN-g3_helicase 8,315 5,432 1,579
PF10088 DUF2326 2,053 1,436 598
PF10236 DAP3 4,312 2,103 736
PF10412 TrwB_AAD_bind 10,297 5,556 2,054
PF10443 RNA12 1,623 892 236
PF10483 Elong_Iki1 2,688 1,498 491
PF10609 ParA 75,845 37,526 7,818
PF10649 DUF2478 2,025 1,476 413
PF10662 PduV-EutP 3,569 1,204 309
PF10923 BrxC_BrxD 4,554 2,635 658
PF10996 Beta-Casp 37,431 19,839 3,079
PF11111 CENP-M 1,159 530 155
PF11398 DUF2813 2,593 807 299
PF11496 HDA2-3 943 600 291
PF11602 NTPase_P4 19 11 9
PF12128 DUF3584 1,294 654 299
PF12344 UvrB 45,834 17,447 839
PF12399 BCA_ABC_TP_C 107,361 47,875 4,448
PF12696 TraG-D_C 15,578 7,557 2,873
PF12774 AAA_6 27,787 16,063 4,752
PF12775 AAA_7 25,698 14,829 4,147
PF12780 AAA_8 26,760 15,174 4,312
PF12781 AAA_9 26,682 14,863 4,154
PF12846 AAA_10 5,411 1,644 649
PF12848 ABC_tran_Xtn 132,844 46,237 4,606
PF13086 AAA_11 64,784 37,189 15,237
PF13087 AAA_12 77,724 42,423 16,944
PF13166 AAA_13 5,996 4,220 1,839
PF13173 AAA_14 50,034 33,345 7,262
PF13175 AAA_15 26,440 19,507 9,545
PF13177 DNA_pol3_delta2 99,686 54,933 13,657
PF13189 Cytidylate_kin2 16,995 10,312 3,164
PF13191 AAA_16 93,770 64,725 28,723
PF13207 AAA_17 6,856 4,481 1,667
PF13238 AAA_18 23,222 13,322 4,225
PF13245 AAA_19 35,224 18,945 5,951
PF13304 AAA_21 58,380 41,152 17,447
PF13307 Helicase_C_2 56,437 26,268 6,783
PF13337 BrxL_ATPase 3,673 2,079 387
PF13361 UvrD_C 159,197 82,728 23,526
PF13401 AAA_22 56,973 36,529 15,359
PF13469 Sulfotransfer_3 44,968 30,905 15,198
PF13476 AAA_23 62,153 38,513 18,172
PF13479 AAA_24 7,597 4,184 1,594
PF13481 AAA_25 58,255 26,333 8,292
PF13500 AAA_26 42,254 20,219 3,907
PF13514 AAA_27 7,248 4,545 2,529
PF13521 AAA_28 19,223 11,303 2,968
PF13538 UvrD_C_2 51,904 26,727 6,937
PF13555 AAA_29 6,358 3,454 1,176
PF13558 SbcC_Walker_B 32,538 16,280 5,880
PF13604 AAA_30 34,116 18,400 5,984
PF13614 AAA_31 155,343 75,716 18,949
PF13654 AAA_32 11,109 5,288 1,168
PF13671 AAA_33 65,347 37,020 10,103
PF13871 Helicase_C_4 7,956 3,594 986
PF13872 AAA_34 7,714 3,721 1,017
PF14396 CFTR_R 1,488 509 41
PF14417 MEDS 7,516 5,712 2,239
PF14516 AAA_35 8,877 6,026 2,350
PF14532 Sigma54_activ_2 6,104 3,481 1,195
PF14617 CMS1 3,117 1,447 422
PF16203 ERCC3_RAD25_C 12,403 4,398 696
PF16260 DUF4914 794 533 53
PF16575 CLP1_P 9,737 5,334 2,172
PF16796 Microtub_bd 1,967 1,518 1,038
PF16813 Cas_St_Csn2 167 81 46
PF16834 CSM2 58 42 24
PF16836 PSY3 102 77 48
PF17213 Hydin_ADK 794 570 198
PF17784 Sulfotransfer_4 10,399 6,686 2,929
PF18082 NAT_N 1,660 1,213 492
PF18128 HydF_dimer 4,259 2,582 229
PF18133 HydF_tetramer 4,349 2,644 273
PF18747 HMUD2 136 25 12
PF18748 HMUDK_HMUD1 154 26 16
PF18751 Ploopntkinase3 310 46 16
PF18766 SWI2_SNF2 28,367 15,645 2,324
PF19044 P-loop_TraG 24,581 8,717 1,977
PF19263 DUF5906 15,665 9,012 4,992
PF19518 RhoGAP_pG1_pG2 2,759 723 203
PF19557 DUF6079 1,487 1,158 563
PF19568 Spore_III_AA 8,328 4,810 1,036
PF19798 Sulfotransfer_5 4,523 3,112 624
PF19842 YqeC 3,454 2,038 940
PF19975 DO-GTPase1 723 544 265
PF19993 DO-GTPase2 1,848 1,312 591
PF19995 iSTAND 453 375 256
PF20030 bpMoxR 5,700 2,410 772
PF20307 divDNAB 171 76 49
PF20454 GpA_nuclease 7,908 3,973 1,396
PF20692 cpSF2-GREB1 2,116 988 144
PF20693 YobI-ATPase 1,177 927 553
PF20702 nSTAND2 308 268 163
PF20703 nSTAND1 16,195 13,182 7,433
PF20720 nSTAND3 4,256 3,413 2,236
PF21090 P-loop_SecA 53,318 24,718 2,713
PF21228 RuBisCO_activase_AAA_helical 2,264 901 157
PF21264 DYNC2H1_AAA_dom 1,565 744 253
PF21445 ADDB_N 8,113 4,154 1,764
PF21448 DNMK 2,134 1,074 594
PF21449 RIF2_ASCE 18 6 1
CL0025 His_Kinase_A 1,947,768 1,131,688 408,125 PF00512 HisKA 986,207 578,541 220,443
PF02518 HATPase_c 1,594,530 927,562 339,340
PF02895 H-kinase_dim 31,124 18,082 3,919
PF07536 HWE_HK 18,134 10,991 3,490
PF07568 HisKA_2 28,681 17,635 7,934
PF07730 HisKA_3 176,627 111,511 35,726
PF10090 HPTransfase 4,202 2,290 568
PF13581 HATPase_c_2 104,681 62,015 17,770
PF13589 HATPase_c_3 112,187 54,384 11,951
PF13749 HATPase_c_4 21,602 14,464 4,439
PF14501 HATPase_c_5 18,003 9,870 5,505
CL0026 CU_oxidase 328,189 143,304 34,337 PF00116 COX2 117,987 35,996 4,506
PF00127 Copper-bind 29,644 18,558 6,718
PF00394 Cu-oxidase 71,013 31,718 5,955
PF00812 Ephrin 7,655 2,974 820
PF02298 Cu_bind_like 17,420 9,766 3,664
PF06481 COX_ARM 8,350 2,580 248
PF06525 SoxE 1,002 664 323
PF07731 Cu-oxidase_2 88,269 43,612 8,854
PF07732 Cu-oxidase_3 95,199 46,776 8,859
PF08526 PAD_N 2,476 820 93
PF08985 DP-EP 214 127 55
PF12306 PixA 1,209 565 214
PF13473 Cupredoxin_1 28,506 16,291 5,414
PF14699 hGDE_N 3,423 1,386 241
PF16986 CzcE 558 347 164
CL0027 RdRP 960,778 492,384 232,243 PF00078 RVT_1 722,180 391,804 178,000
PF00680 RdRP_1 61,061 8,967 3,648
PF00972 Flavi_NS5 14,304 1,715 221
PF00978 RdRP_2 11,102 2,154 1,032
PF00998 RdRP_3 49,604 6,704 1,385
PF02123 RdRP_4 6,975 1,237 772
PF04197 Birna_RdRp_palm 1,184 56 31
PF05919 Mitovir_RNA_pol 1,906 1,425 1,087
PF07727 RVT_2 90,129 77,133 45,898
PF20049 DUF6451 2,552 2,217 1,153
PF20483 Flavi_NS5_thumb 13,001 1,481 147
PF20488 Birna_VP1_thumb 314 23 14
CL0028 AB_hydrolase 2,310,645 1,319,545 359,224 PF00135 COesterase 101,115 60,023 21,508
PF00151 Lipase 20,034 10,034 4,145
PF00326 Peptidase_S9 181,335 105,815 26,702
PF00450 Peptidase_S10 54,326 30,436 9,646
PF00561 Abhydrolase_1 543,396 306,537 75,120
PF00756 Esterase 95,369 53,081 12,866
PF00975 Thioesterase 59,465 34,959 14,651
PF01083 Cutinase 16,052 8,126 2,129
PF01674 Lipase_2 6,901 4,222 1,259
PF01738 DLH 88,728 51,334 11,376
PF01764 Lipase_3 47,409 28,118 11,826
PF02089 Palm_thioest 10,041 5,427 1,925
PF02129 Peptidase_S15 57,173 31,887 7,392
PF02230 Abhydrolase_2 44,067 25,886 7,208
PF02273 Acyl_transf_2 296 158 86
PF02450 LCAT 12,851 7,130 3,097
PF03096 Ndr 11,411 3,519 912
PF03283 PAE 9,473 5,117 2,136
PF03403 PAF-AH_p_II 15,678 9,885 3,340
PF03583 LIP 15,639 8,566 2,298
PF03893 Lipase3_N 2,837 1,344 253
PF03959 FSH1 12,993 7,737 3,320
PF04083 Abhydro_lipase 10,801 6,691 2,604
PF04301 BioG 1,434 615 269
PF05057 DUF676 17,026 10,047 4,276
PF05277 DUF726 7,285 3,858 1,261
PF05448 AXE1 13,899 9,020 2,679
PF05576 Peptidase_S37 2,450 1,240 287
PF05577 Peptidase_S28 15,208 9,001 3,546
PF05677 DUF818 349 260 194
PF05705 DUF829 7,260 4,020 1,691
PF05728 UPF0227 11,667 5,058 1,134
PF05990 DUF900 8,367 5,135 2,189
PF06028 DUF915 4,606 1,751 672
PF06057 VirJ 3,710 1,463 465
PF06259 Abhydrolase_8 7,477 4,686 1,373
PF06342 DUF1057 591 448 269
PF06441 EHN 22,214 12,711 1,843
PF06500 FrsA-like 6,522 3,175 793
PF06821 Ser_hydrolase 15,237 7,925 1,824
PF06850 PHB_depo_C 8,442 3,851 312
PF07082 DUF1350 2,310 1,189 369
PF07167 PhaC_N 15,048 7,703 896
PF07176 DUF1400 3,110 1,824 614
PF07224 Chlorophyllase 2,327 1,625 764
PF07519 Tannase 14,775 8,712 2,573
PF07819 PGAP1 11,676 6,945 3,123
PF07859 Abhydrolase_3 124,005 69,748 19,843
PF08237 PE-PPE 4,290 2,456 823
PF08386 Abhydrolase_4 30,572 19,682 6,364
PF08538 DUF1749 2,918 1,643 555
PF08840 BAAT_C 8,507 4,453 1,532
PF09752 ABHD18 3,591 1,688 684
PF09994 DUF2235 17,194 11,318 3,985
PF10081 Abhydrolase_9 4,057 2,306 470
PF10142 PhoPQ_related 3,877 2,125 995
PF10230 LIDHydrolase 4,064 2,228 985
PF10340 Say1_Mug180 542 388 230
PF10503 Esterase_PHB 20,515 13,627 4,616
PF10561 C2orf69 1,612 752 272
PF10605 3HBOH 1,956 1,071 177
PF11144 DUF2920 1,711 467 176
PF11187 Mbeg1-like 4,329 2,091 1,228
PF11288 DUF3089 3,396 2,594 784
PF11339 DUF3141 2,612 1,528 292
PF12048 DUF3530 2,575 1,313 520
PF12146 Hydrolase_4 149,755 86,652 28,988
PF12695 Abhydrolase_5 3,789 2,309 877
PF12697 Abhydrolase_6 239,574 147,824 43,734
PF12715 Abhydrolase_7 2,839 1,971 611
PF12740 Chlorophyllase2 3,818 2,582 1,108
PF16929 Asp2 1,125 450 197
PF19878 DUF6351 1,586 1,183 377
PF20091 Abhydrolase_10 4,408 3,014 939
PF20408 Abhydrolase_11 15,405 8,757 1,680
PF20434 BD-FAE 60,780 40,644 12,664
PF20591 DUF6792 422 284 145
PF21498 Obc1_C 46 15 5
CL0029 Cupin 1,679,948 886,131 220,282 PF00027 cNMP_binding 299,517 164,147 49,109
PF00190 Cupin_1 30,040 14,390 4,021
PF00908 dTDP_sugar_isom 41,982 25,668 2,378
PF01050 MannoseP_isomer 31,035 16,448 2,564
PF01238 PMI_typeI_C 3,163 1,282 240
PF01987 AIM24 28,732 12,009 1,795
PF02041 Auxin_BP 798 492 160
PF02311 AraC_binding 110,040 55,216 18,291
PF02373 JmjC 46,281 20,839 6,362
PF02375 JmjN 18,942 9,004 2,111
PF02668 TauD 72,615 38,704 9,639
PF02678 Pirin 63,092 30,842 2,866
PF03079 ARD 10,571 4,879 813
PF03171 2OG-FeII_Oxy 89,226 44,928 9,929
PF03336 Pox_C4_C10 282 70 44
PF04074 DUF386 11,769 4,416 1,465
PF04115 Ureidogly_lyase 10,449 5,101 933
PF04209 HgmA_C 15,566 5,637 517
PF04622 ERG2_Sigma1R 3,019 1,422 298
PF04831 Popeye 3,969 1,473 555
PF04962 KduI 19,164 8,379 775
PF05118 Asp_Arg_Hydrox 15,899 7,439 2,485
PF05523 FdtA 7,010 5,062 945
PF05721 PhyH 86,074 52,093 13,425
PF05726 Pirin_C 38,673 19,321 1,905
PF05899 Cupin_3 20,456 8,301 1,782
PF05962 HutD 8,347 4,367 1,337
PF05995 CDO_I 12,598 6,531 1,480
PF06052 3-HAO 7,406 3,671 444
PF06172 Cupin_5 12,392 7,468 1,199
PF06249 EutQ 4,078 1,684 402
PF06339 Ectoine_synth 5,740 2,110 171
PF06560 GPI 3,161 2,026 494
PF06719 AraC_N 17,938 8,075 1,373
PF06865 Ppnp 8,009 3,019 181
PF07350 Gig2-like 5,164 2,070 437
PF07385 Lyx_isomer 3,411 1,807 163
PF07847 PCO_ADO 4,538 2,320 873
PF07883 Cupin_2 250,016 138,343 29,000
PF08007 JmjC_2 16,778 8,324 2,680
PF08487 VIT 21,385 12,486 4,507
PF08943 CsiD 1,728 347 59
PF09313 DUF1971 4,281 1,379 326
PF09859 Oxygenase-NA 5,048 2,760 206
PF10014 2OG-Fe_Oxy_2 4,850 2,558 569
PF10637 Ofd1_CTDD 3,335 1,694 500
PF11004 Kdo_hydroxy 1,426 629 119
PF11699 CENP-C_C 2,539 1,426 609
PF12851 Tet_JBP 4,050 2,319 741
PF12852 Cupin_6 21,540 11,186 2,093
PF12933 FTO_NTD 1,513 440 142
PF12973 Cupin_7 15,253 9,055 1,860
PF13532 2OG-FeII_Oxy_2 41,031 22,522 5,418
PF13621 Cupin_8 31,044 17,250 6,353
PF13640 2OG-FeII_Oxy_3 58,488 31,467 10,377
PF13661 2OG-FeII_Oxy_4 4,404 2,492 823
PF13757 VIT_2 1,429 680 127
PF13759 2OG-FeII_Oxy_5 6,890 5,088 2,190
PF14033 DUF4246 4,996 3,319 1,386
PF14226 DIOX_N 78,820 40,234 8,617
PF14499 DUF4437 2,032 1,332 426
PF14525 AraC_binding_2 22,633 12,204 4,396
PF16161 DUF4867 1,407 704 141
PF16802 DUF5070 22 14 2
PF16867 DMSP_lyase 2,173 1,282 437
PF17954 Pirin_C_2 21,188 9,738 1,011
PF18637 AUDH_Cupin 350 198 83
PF19480 DUF6016 2,048 977 211
PF20510 HgmA_N 19,418 7,551 717
PF20511 PMI_typeI_cat 25,471 12,746 2,484
PF20515 2OG-FeII_Oxy_6 2,178 1,711 851
PF21621 MPI_cupin_dom 11,530 5,201 961
CL0030 Ion_channel 483,563 234,567 68,613 PF00060 Lig_chan 52,788 23,002 7,964
PF00520 Ion_trans 235,554 114,984 31,737
PF01007 IRK 16,754 4,247 1,108
PF02386 TrkH 54,163 28,167 5,922
PF03814 KdpA 17,630 6,419 643
PF07885 Ion_trans_2 92,074 51,084 18,664
PF08016 PKD_channel 15,613 7,879 3,560
PF20519 Polycystin_dom 9,329 5,345 2,542
CL0031 Phosphatase 701,403 351,145 84,269 PF00102 Y_phosphatase 94,426 41,829 12,688
PF00581 Rhodanese 287,290 157,626 33,948
PF00782 DSPc 78,560 36,280 12,457
PF01451 LMWPc 85,543 49,489 8,408
PF02302 PTS_IIB 56,336 17,769 2,636
PF02383 Syja_N 23,957 9,907 2,542
PF03162 Y_phosphatase2 7,084 4,153 1,674
PF04179 Init_tRNA_PT 2,117 1,213 367
PF04273 BLH_phosphatase 10,841 6,158 1,534
PF04722 Ssu72 3,971 1,647 369
PF05706 CDKN3 3,220 1,776 730
PF06602 Myotub-related 28,466 10,139 2,541
PF13350 Y_phosphatase3 23,023 13,730 4,849
PF14566 PTPlike_phytase 3,839 1,763 637
PF14671 DSPn 6,800 2,788 803
PF16809 NleF_casp_inhib 98 33 19
CL0032 Dim_A_B_barrel 563,152 274,507 49,186 PF01037 AsnC_trans_reg 173,861 63,267 8,057
PF02426 MIase 5,525 2,223 415
PF03795 YCII 66,017 37,313 5,433
PF03927 NapD 4,152 2,143 707
PF03992 ABM 96,915 52,665 12,044
PF04261 Dyp_perox_N 18,326 7,233 596
PF04486 SchA_CurD 1,024 466 48
PF04673 Cyclase_polyket 1,820 792 68
PF05336 rhaM 15,851 8,395 882
PF06778 Chlor_dismutase 11,421 5,027 503
PF07045 DUF1330 20,912 11,966 2,330
PF07110 EthD 13,640 8,418 2,564
PF07237 DUF1428 6,073 3,505 282
PF07682 SOR 134 71 18
PF07876 Dabb 24,612 14,345 3,387
PF07978 NIPSNAP 21,919 11,185 2,159
PF08734 GYD 7,894 4,632 940
PF08803 ydhR 2,776 1,331 346
PF09448 MmlI 59 29 6
PF11639 HapK 535 365 74
PF11695 DUF3291 3,707 2,609 456
PF11746 DUF3303 3,661 2,063 599
PF13816 Dehydratase_hem 1,843 885 233
PF13826 DUF4188 3,745 2,426 501
PF14026 SCO4226-like 6,318 3,881 562
PF14114 DUF4286 4,258 2,801 777
PF16291 DUF4937 1,575 436 138
PF17074 Darcynin 809 406 102
PF17805 AsnC_trans_reg2 9,557 6,106 852
PF18075 FtsX_ECD 29,989 14,878 3,271
PF18232 Chalcone_N 116 67 14
PF20628 Dyp_perox_C 22,011 9,208 1,191
PF21105 DyP_N 2,594 1,666 433
CL0033 POZ 319,921 132,711 51,958 PF00651 BTB 229,834 101,398 41,205
PF02214 BTB_2 60,856 19,246 5,889
PF03931 Skp1_POZ 13,584 6,265 2,421
PF07707 BACK 80,688 25,568 8,464
PF11822 SANBR_BTB 1,392 617 241
PF16017 BTB_3 2,955 925 163
PF21536 KLHL33-like_BTB_POZ 1,557 635 203
CL0036 TIM_barrel 7,649,852 3,773,576 674,774 PF00016 RuBisCO_large 193,323 21,627 3,222
PF00113 Enolase_C 69,972 24,475 2,613
PF00121 TIM 65,196 30,570 4,292
PF00128 Alpha-amylase 244,802 121,559 18,606
PF00150 Cellulase 65,669 38,678 12,163
PF00215 OMPdecase 60,110 29,327 3,840
PF00218 IGPS 44,874 21,548 2,946
PF00224 PK 66,993 27,885 5,225
PF00232 Glyco_hydro_1 82,440 38,675 8,465
PF00248 Aldo_ket_red 367,806 188,366 28,862
PF00290 Trp_syntA 43,809 21,642 2,758
PF00296 Bac_luciferase 264,854 126,079 17,702
PF00311 PEPcase 30,131 12,157 2,451
PF00331 Glyco_hydro_10 25,763 16,199 4,841
PF00332 Glyco_hydro_17 26,384 13,220 3,331
PF00387 PI-PLC-Y 32,008 13,400 2,409
PF00388 PI-PLC-X 40,375 17,354 3,986
PF00449 Urease_alpha 19,101 5,258 534
PF00463 ICL 21,581 5,998 568
PF00478 IMPDH 73,713 24,570 2,240
PF00490 ALAD 41,880 17,198 1,299
PF00682 HMGL-like 154,800 67,596 6,269
PF00697 PRAI 38,895 22,372 4,360
PF00701 DHDPS 123,055 58,283 8,624
PF00704 Glyco_hydro_18 86,372 46,358 15,569
PF00724 Oxidored_FMN 124,605 60,419 8,645
PF00728 Glyco_hydro_20 44,774 25,263 7,454
PF00793 DAHP_synth_1 79,946 33,972 2,733
PF00809 Pterin_bind 93,904 47,017 5,912
PF00834 Ribul_P_3_epim 57,803 26,679 3,748
PF00923 TAL_FSA 56,992 24,618 2,887
PF00933 Glyco_hydro_3 130,976 71,876 13,614
PF00962 A_deaminase 45,452 20,999 3,876
PF00977 His_biosynth 88,408 38,892 4,205
PF01026 TatD_DNase 86,335 44,806 8,773
PF01055 Glyco_hydro_31_2nd 59,148 30,176 7,610
PF01070 FMN_dh 62,660 29,777 5,123
PF01081 Aldolase 39,138 18,873 2,707
PF01116 F_bP_aldolase 56,426 20,674 2,313
PF01120 Alpha_L_fucos 32,915 20,501 4,502
PF01168 Ala_racemase_N 131,543 71,347 11,096
PF01180 DHO_dh 71,215 35,564 4,800
PF01183 Glyco_hydro_25 29,049 14,751 4,965
PF01207 Dus 88,664 41,207 6,758
PF01208 URO-D 69,299 40,108 9,024
PF01229 Glyco_hydro_39 8,796 5,809 2,053
PF01244 Peptidase_M19 38,946 22,116 4,621
PF01261 AP_endonuc_2 232,647 127,331 24,491
PF01274 MS_TIM-barrel 27,330 10,844 737
PF01301 Glyco_hydro_35 28,737 14,582 3,713
PF01373 Glyco_hydro_14 5,360 2,485 783
PF01474 DAHP_synth_2 20,348 7,304 820
PF01487 DHquinase_I 16,943 8,676 2,756
PF01619 Pro_dh 40,168 19,714 3,042
PF01630 Glyco_hydro_56 6,946 2,912 850
PF01642 MM_CoA_mutase 56,179 28,188 3,604
PF01645 Glu_synthase 63,659 28,070 2,721
PF01680 SOR_SNZ 18,589 5,685 407
PF01702 TGT 55,187 25,470 3,579
PF01717 Meth_synt_2 45,184 20,037 2,211
PF01729 QRPTase_C 44,023 22,807 2,464
PF01791 DeoC 60,514 27,661 2,882
PF01876 RNase_P_p30 5,831 3,332 1,205
PF01884 PcrB 7,563 4,383 563
PF01904 DUF72 32,204 19,318 3,679
PF01964 ThiC_Rad_SAM 30,138 11,175 866
PF01979 Amidohydro_1 357,874 182,908 29,851
PF02007 MtrH 1,546 903 237
PF02055 Glyco_hydro_30 14,717 8,425 2,210
PF02057 Glyco_hydro_59 3,150 1,553 460
PF02065 Melibiase 21,676 12,448 3,106
PF02126 PTE 10,900 5,654 1,457
PF02156 Glyco_hydro_26 11,627 7,811 2,807
PF02219 MTHFR 51,770 25,534 3,442
PF02286 Dehydratase_LU 2,170 596 96
PF02324 Glyco_hydro_70 815 259 110
PF02446 Glyco_hydro_77 28,989 15,889 3,733
PF02449 Glyco_hydro_42 23,109 14,310 4,402
PF02548 Pantoate_transf 42,402 19,449 1,791
PF02574 S-methyl_trans 62,778 31,513 5,373
PF02581 TMP-TENI 55,377 31,063 6,182
PF02614 UxaC 13,434 6,752 677
PF02638 GHL10 19,093 11,186 3,555
PF02679 ComA 4,686 2,869 520
PF02784 Orn_Arg_deC_N 94,684 42,277 6,025
PF02811 PHP 151,730 82,667 15,818
PF02836 Glyco_hydro_2_C 71,729 40,586 9,755
PF02896 PEP-utilizers_C 89,435 39,602 5,497
PF03009 GDPD 103,162 55,264 15,738
PF03060 NMO 72,373 35,818 3,916
PF03102 NeuB 22,097 14,127 2,336
PF03198 Glyco_hydro_72 7,277 3,885 896
PF03328 HpcH_HpaI 78,370 39,282 7,150
PF03437 BtpA 6,699 3,652 716
PF03473 MOSC 54,262 31,275 5,525
PF03537 Glyco_hydro_114 9,085 6,057 2,001
PF03599 CdhD 6,685 4,650 780
PF03644 Glyco_hydro_85 4,974 2,664 1,044
PF03659 Glyco_hydro_71 4,883 2,986 1,118
PF03662 Glyco_hydro_79n 5,013 2,470 767
PF03740 PdxJ 25,285 12,277 733
PF03786 UxuA 15,484 7,466 825
PF03851 UvdE 5,992 3,556 695
PF03932 CutC 17,467 8,566 1,835
PF04055 Radical_SAM 758,409 407,205 76,117
PF04095 NAPRTase 33,387 13,023 1,231
PF04131 NanE 8,290 3,385 371
PF04309 G3P_antiterm 5,010 2,274 435
PF04476 4HFCP_synth 2,813 1,642 520
PF04481 DUF561 1,440 758 151
PF04898 Glu_syn_central 38,897 16,008 1,690
PF04909 Amidohydro_2 134,584 79,256 16,953
PF05089 NAGLU 5,926 3,150 966
PF05114 DUF692 14,356 8,599 1,246
PF05369 MtmB 895 610 246
PF05690 ThiG 27,420 9,978 511
PF05691 Raffinose_syn 6,028 3,215 1,222
PF05853 BKACE 23,553 11,178 1,612
PF06134 RhaA 5,294 2,278 179
PF06187 DUF993 4,695 2,143 131
PF06368 Met_asp_mut_E 2,292 1,157 180
PF06751 EutB 8,303 2,756 173
PF07071 KDGP_aldolase 3,013 548 60
PF07476 MAAL_C 1,603 755 93
PF07488 Glyco_hydro_67M 4,483 2,668 254
PF07505 DUF5131 8,032 5,560 1,490
PF07555 NAGidase 7,649 3,743 1,180
PF07745 Glyco_hydro_53 7,548 4,381 1,306
PF07969 Amidohydro_3 113,766 63,594 14,240
PF08013 GatZ_KbaZ-like 5,075 1,902 337
PF08267 Meth_synt_1 19,575 7,359 827
PF08306 Glyco_hydro_98M 367 157 90
PF08924 Rv2525c_GlyHyd-like 5,685 3,301 1,023
PF09043 Lys-AminoMut_A 2,577 1,373 136
PF09370 PEP_hydrolase 5,580 2,532 347
PF09863 DUF2090 4,854 1,722 232
PF10223 Menorin 2,270 1,307 514
PF10566 Glyco_hydro_97 12,966 7,056 1,186
PF11308 Glyco_hydro_129 1,603 752 226
PF11790 Glyco_hydro_cc 8,266 5,494 2,396
PF12138 Spherulin4 4,465 2,579 919
PF12228 DUF3604 6,647 5,258 1,757
PF12876 Cellulase-like 476 305 69
PF12890 DHOase 339 248 107
PF12891 Glyco_hydro_44 1,343 1,014 431
PF12905 Glyco_hydro_101 1,736 788 283
PF13199 Glyco_hydro_66 1,227 752 342
PF13200 DUF4015 5,760 4,033 1,383
PF13204 DUF4038 6,130 4,425 1,447
PF13263 PHP_C 12,012 8,185 2,601
PF13320 GH123_cat 5,379 3,783 1,871
PF13378 MR_MLE_C 140,612 66,482 9,925
PF13653 GDPD_2 2,556 1,307 320
PF13714 PEP_mutase 43,514 21,027 2,714
PF14010 PEPcase_2 1,281 822 200
PF14307 Glyco_tran_WbsX 5,073 3,753 1,526
PF14488 DUF4434 2,583 1,340 443
PF14587 Glyco_hydr_30_2 4,084 2,461 676
PF14701 hDGE_amylase 4,522 2,103 537
PF14871 GHL6 3,027 2,401 833
PF14872 GHL5 340 244 44
PF14883 GHL13 2,756 873 251
PF14885 GHL15 1,490 1,235 711
PF15617 C-C_Bond_Lyase 3,793 1,539 310
PF15979 Glyco_hydro_115 5,956 3,654 793
PF16126 DUF4838 5,584 4,795 2,830
PF16141 GH18_BT1044-like 1,486 525 193
PF16154 DUF4862 1,419 384 116
PF16257 UxaE 2,307 1,798 373
PF16317 Glyco_hydro_99 3,542 1,880 896
PF16387 DUF4996 2,078 957 295
PF16402 DUF5010 238 186 99
PF16499 Melibiase_2 20,628 11,852 2,692
PF16552 OAM_alpha 646 431 43
PF16670 PI-PLC-C1 2,866 1,777 518
PF17285 PRMT5_TIM 4,102 1,852 531
PF18952 DUF5696 2,436 1,846 923
PF19200 MupG_N 4,905 1,772 425
PF19238 Radical_SAM_2 5,653 3,570 659
PF19326 AMP_deaminase 11,518 3,948 890
PF19345 MTHFR_2 591 227 17
PF19567 CpsB_CapC 11,517 7,104 2,407
PF19773 DUF6259 1,667 1,469 905
PF19799 DUF6282 2,871 1,846 494
PF20903 SPL 6,710 3,852 722
CL0037 Lysozyme 427,328 219,833 58,826 PF00062 Lys 5,171 2,753 1,058
PF00182 Glyco_hydro_19 16,577 7,462 2,303
PF00912 Transgly 128,324 65,373 12,105
PF00959 Phage_lysozyme 19,570 8,329 2,623
PF01374 Glyco_hydro_46 2,498 1,407 365
PF01464 SLT 142,084 77,468 24,714
PF01832 Glucosaminidase 32,554 16,257 5,753
PF03998 Utp11 3,880 1,993 532
PF05497 Destabilase 1,419 1,050 507
PF05838 Glyco_hydro_108 7,018 3,990 1,315
PF06737 Transglycosylas 13,554 7,444 1,422
PF06871 TraH_2 528 299 41
PF07759 DUF1615 3,605 863 132
PF10464 Peptidase_U40 36 5 3
PF11508 DUF3218 15 4 3
PF13406 SLT_2 34,824 17,828 3,206
PF13647 Glyco_hydro_80 17 6 3
PF13702 Lysozyme_like 4,290 1,116 392
PF16754 Pesticin 569 424 285
PF18013 Phage_lysozyme2 4,039 2,168 1,333
PF18896 SLT_3 631 496 286
PF19489 SLT_4 4,892 2,407 231
PF21087 Glyco_hydro_134 512 247 76
PF21277 T6SS_VgrG3-like_C 797 532 344
PF21480 PlyCA_N 23 10 8
CL0039 HUP 1,877,221 951,521 164,723 PF00133 tRNA-synt_1 183,630 93,010 12,949
PF00579 tRNA-synt_1b 123,571 57,597 5,791
PF00582 Usp 211,959 121,974 35,451
PF00733 Asn_synthase 79,327 47,778 15,245
PF00749 tRNA-synt_1c 114,560 57,598 6,756
PF00750 tRNA-synt_1d 60,163 29,750 4,585
PF00764 Arginosuc_synth 44,343 14,431 991
PF00875 DNA_photolyase 47,508 26,550 4,340
PF01012 ETF 104,598 45,940 5,497
PF01171 ATP_bind_3 75,839 42,524 12,457
PF01406 tRNA-synt_1e 69,082 34,890 4,280
PF01467 CTP_transf_like 156,228 80,641 14,704
PF01507 PAPS_reduct 69,895 29,771 4,514
PF01747 ATP-sulfurylase 17,170 8,008 866
PF01902 Diphthami_syn_2 13,263 8,319 2,005
PF01921 tRNA-synt_1f 10,771 5,431 763
PF02540 NAD_synthase 104,805 47,816 5,107
PF02568 ThiI 19,599 9,416 1,844
PF02569 Pantoate_ligase 38,926 21,440 2,727
PF02677 QueH 10,734 5,171 952
PF03054 tRNA_Me_trans 54,224 25,713 3,456
PF03720 UDPG_MGDP_dh_C 90,053 47,960 4,497
PF04244 DPRP 10,987 6,721 726
PF05636 HIGH_NTase1 8,045 4,125 1,331
PF06508 QueC 30,115 15,263 2,160
PF06574 FAD_syn 44,359 23,592 5,073
PF08218 Citrate_ly_lig 3,946 1,351 404
PF09334 tRNA-synt_1g 106,971 50,954 5,993
PF10079 BshC 6,792 4,748 1,516
PF13603 tRNA-synt_1_2 52,280 25,721 2,501
PF16581 HIGH_NTase1_ass 251 130 13
PF16715 CDPS 967 568 240
CL0040 tRNA_synt_II 752,010 351,645 49,708 PF00152 tRNA-synt_2 161,421 72,494 8,767
PF00587 tRNA-synt_2b 206,922 92,371 7,225
PF01409 tRNA-synt_2d 60,870 26,009 2,674
PF01411 tRNA-synt_2c 74,257 36,782 5,714
PF02091 tRNA-synt_2e 24,101 7,463 536
PF03099 BPL_LplA_LipB 77,111 43,060 12,452
PF03590 AsnA 7,734 2,919 191
PF04017 DUF366 783 500 103
PF13393 tRNA-synt_His 82,500 40,980 6,291
PF16917 BPL_LplA_LipB_2 1,145 787 219
PF17759 tRNA_synthFbeta 55,248 28,366 5,639
CL0041 Death 89,581 41,201 15,130 PF00531 Death 44,986 19,369 6,024
PF00619 CARD 23,574 10,534 4,029
PF01335 DED 6,495 2,932 925
PF02758 PYRIN 8,552 4,380 1,947
PF14786 Death_2 323 207 104
PF16739 CARD_2 3,247 1,352 378
PF18461 Atypical_Card 745 280 41
PF19954 EAD10 265 226 159
PF19955 EAD1 1,447 1,198 806
PF19956 EAD2 1,207 847 356
PF19957 EAD5 134 100 45
PF19958 EAD6 9 9 7
PF19960 EAD7 832 759 588
PF19961 EAD8 323 279 187
PF20689 bDLD1 67 62 50
PF20690 bDLD3 81 74 56
PF20707 bDLD2 14 7 6
PF21733 Death_3 335 191 64
CL0042 Flavoprotein 306,707 149,699 25,456 PF00258 Flavodoxin_1 78,719 34,105 5,964
PF02525 Flavodoxin_2 61,954 27,719 4,242
PF03358 FMN_red 131,358 69,287 10,409
PF07972 Flavodoxin_NdrI 8,374 2,773 271
PF12641 Flavodoxin_3 2,689 1,456 510
PF12682 Flavodoxin_4 8,655 5,302 1,663
PF12724 Flavodoxin_5 14,970 9,372 3,043
CL0043 Chelatase 282,326 144,273 30,646 PF00148 Oxidored_nitro 31,645 13,088 1,878
PF00762 Ferrochelatase 39,598 19,004 2,697
PF01297 ZnuA 58,892 31,464 7,825
PF01497 Peripla_BP_2 125,927 65,919 14,790
PF01903 CbiX 21,120 12,498 2,797
PF06180 CbiK 5,063 2,283 658
PF11844 DUF3364 2,194 643 29
CL0044 Ferritin 363,023 171,170 30,247 PF00210 Ferritin 85,043 35,846 4,853
PF00268 Ribonuc_red_sm 42,516 12,208 1,616
PF01786 AOX 6,054 3,342 828
PF02332 Phenol_Hydrox 6,702 2,173 270
PF02915 Rubrerythrin 41,673 23,231 4,136
PF03232 COQ7 12,398 6,344 860
PF03405 FA_desaturase_2 10,244 3,633 575
PF03713 DUF305 23,441 14,418 3,061
PF04305 DUF455 9,262 5,500 886
PF05067 Mn_catalase 11,954 4,817 474
PF05138 PaaA_PaaC 21,744 9,804 749
PF05974 DUF892 13,226 6,718 1,470
PF06175 MiaE 9,421 3,746 321
PF07875 Coat_F 7,015 3,911 833
PF09537 DUF2383 7,715 4,654 1,253
PF09968 DUF2202 2,191 1,764 915
PF11266 Ald_deCOase 1,068 475 69
PF11553 DUF3231 3,953 2,658 594
PF11583 AurF 9,992 3,884 647
PF12902 Ferritin-like 2,767 1,888 655
PF13628 DUF4142 14,167 8,189 2,808
PF13668 Ferritin_2 12,563 8,028 1,818
PF13794 MiaE_2 4,015 1,565 186
PF14530 DUF4439 3,360 2,081 466
PF18536 DUF5623 153 114 46
PF19825 DUF6306 493 284 87
PF20402 DUF6692 133 65 21
CL0045 Rubredoxin 76,930 41,397 5,193 PF00301 Rubredoxin 26,498 12,376 1,230
PF01215 COX5B 4,142 2,084 513
PF06397 Desulfoferrod_N 5,407 3,494 351
PF08421 Methyltransf_13 8,266 5,475 966
PF10276 zf-CHCC 11,522 5,960 951
PF21349 RUBY_RBDX 21,576 12,290 1,253
CL0046 Thiolase 567,490 268,518 51,160 PF00108 Thiolase_N 201,301 79,471 6,173
PF00109 ketoacyl-synt 215,146 114,934 30,448
PF00195 Chal_sti_synt_N 19,330 8,407 1,334
PF01154 HMG_CoA_synt_N 12,065 4,850 747
PF02797 Chal_sti_synt_C 19,812 8,933 1,441
PF02801 Ketoacyl-synt_C 205,647 108,741 27,054
PF02803 Thiolase_C 190,654 73,409 4,494
PF07451 SpoVAD 5,211 2,603 236
PF08392 FAE1_CUT1_RppA 9,713 4,467 1,120
PF08540 HMG_CoA_synt_C 11,680 4,595 795
PF08541 ACP_syn_III_C 87,683 41,762 4,656
PF08545 ACP_syn_III 73,031 34,681 3,665
PF11394 DUF2875 655 313 65
PF13723 Ketoacyl-synt_2 6,127 3,368 933
PF16197 KAsynt_C_assoc 66,877 45,064 17,548
PF20995 DUF2875_C 689 332 81
CL0047 CuAO_N2_N3 14,569 6,638 1,194 PF02727 Cu_amine_oxidN2 11,861 5,213 920
PF02728 Cu_amine_oxidN3 11,661 5,083 782
PF09248 DUF1965 1,184 671 159
CL0048 LolA_LolB 137,660 80,162 28,144 PF00811 Ependymin 2,385 1,264 518
PF03548 LolA 25,348 14,018 4,494
PF03550 LolB 9,497 4,504 1,568
PF03888 MucB_RseB 8,176 3,988 1,362
PF04507 DUF576 1,047 387 103
PF04788 DUF620 3,209 1,311 294
PF06475 Glycolipid_bind 4,273 2,437 629
PF07044 DUF1329 9,816 4,545 869
PF07161 LppX_LprAFG 2,664 1,685 586
PF07608 DUF1571 1,694 1,184 589
PF09697 Porph_ging 7,940 5,691 2,291
PF09865 DUF2092 2,417 1,827 921
PF11306 DUF3108 19,460 12,578 4,715
PF11659 DUF3261 2,158 1,147 459
PF11904 GPCR_chapero_1 7,933 2,917 681
PF14125 DUF4292 5,123 3,607 1,558
PF14371 DUF4412 2,382 2,033 1,264
PF16584 LolA_2 1,521 859 295
PF17131 LolA_like 13,122 9,562 2,950
PF18234 VioE 84 45 8
PF19574 LolA_3 3,141 1,654 492
PF19630 DUF6134 1,912 1,534 783
PF20316 DUF6612 2,342 1,484 905
CL0050 HotDog 582,464 300,602 62,417 PF01575 MaoC_dehydratas 95,688 47,577 7,321
PF01643 Acyl-ACP_TE 12,038 6,374 2,182
PF02551 Acyl_CoA_thio 18,329 6,955 932
PF03061 4HBT 174,525 86,807 16,398
PF03756 AfsA 3,094 1,921 763
PF07977 FabA 56,753 25,233 3,709
PF09500 YiiD_C 5,118 1,928 530
PF10862 FcoT 483 268 76
PF13279 4HBT_2 94,844 52,496 10,665
PF13452 MaoC_dehydrat_N 29,630 15,938 2,917
PF13622 4HBT_3 42,722 19,951 3,745
PF14539 DUF4442 13,797 7,191 1,262
PF14765 PS-DH 46,088 31,016 12,523
PF18238 LnmK_N_HDF 122 77 24
PF19315 MC_hydratase 7,206 3,132 218
PF20789 4HBT_3C 22,933 12,161 2,812
PF20791 Acyl-ACP_TE_C 11,080 5,753 2,142
PF21089 PKS_DH_N 44,997 30,109 11,836
CL0051 NTF2 426,352 243,067 68,868 PF00866 Ring_hydroxyl_B 11,466 4,985 936
PF02136 NTF2 19,813 8,481 2,616
PF02982 Scytalone_dh 1,327 648 160
PF03284 PHZA_PHZB 491 234 47
PF04280 Tim44 21,425 10,060 2,156
PF04335 VirB8 12,079 3,579 1,067
PF05223 MecA_N 8,424 4,205 771
PF05494 MlaC 17,857 9,978 3,086
PF07080 DUF1348 9,673 4,442 275
PF07107 WI12 1,087 642 179
PF07366 SnoaL 26,726 17,657 5,810
PF07858 LEH 3,077 1,838 503
PF07961 MBA1 644 379 196
PF08294 TIM21 3,534 1,893 581
PF08332 CaMKII_AD 16,157 7,606 1,106
PF08472 S6PP_C 1,088 494 142
PF08695 Coa1 4,300 2,569 1,032
PF10184 DUF2358 5,148 2,995 1,088
PF10429 Mtr2 246 160 56
PF11393 T4BSS_DotI_IcmL 1,765 849 426
PF11444 DUF2895 2,224 479 116
PF11533 AtzH-like 3,103 1,622 177
PF12642 TpcC 3,133 1,229 505
PF12680 SnoaL_2 105,056 64,345 16,962
PF12707 DUF3804 74 50 33
PF12870 DUF4878 744 482 313
PF12883 DUF3828 3,648 1,059 432
PF12893 Lumazine_bd_2 7,801 5,171 1,516
PF13026 DUF3887 3,117 1,956 917
PF13211 DUF4019 2,100 1,444 661
PF13355 ARC6-like_IMS 2,063 1,130 392
PF13474 SnoaL_3 22,883 14,240 5,171
PF13577 SnoaL_4 39,396 24,452 7,301
PF14254 DUF4348 740 375 161
PF14534 DUF4440 37,639 26,765 10,222
PF14729 DUF4467 258 87 26
PF15008 DUF4518 969 518 195
PF16022 DUF4783 2,041 1,479 604
PF16111 DUF4829 381 305 190
PF16156 DUF4864 2,882 1,887 695
PF16247 DUF4904 25 19 10
PF16800 Endopep_inhib 606 285 146
PF17117 DUF5104 459 297 184
PF17118 DUF5105 751 292 182
PF17354 DUF5382 34 23 13
PF17775 UPF0225 14,713 8,152 1,187
PF18042 ORF_12_N 792 394 114
PF20409 SnoaL_5 2,004 1,398 262
PF20462 DUF6715 363 205 109
PF20795 DUF6841 482 342 195
PF20839 DUF5382_C 32 20 13
PF20840 DUF5382_N 33 23 14
PF21497 TcpC-like_C 71 25 17
CL0052 NTN 543,712 257,007 51,328 PF00227 Proteasome 111,118 39,835 6,625
PF00310 GATase_2 41,032 17,338 2,200
PF01019 G_glu_transpept 74,222 40,539 8,082
PF01112 Asparaginase_2 29,887 15,963 3,039
PF01804 Penicil_amidase 31,121 19,967 5,973
PF02275 CBAH 14,386 6,408 1,686
PF03417 AAT 13,458 8,704 2,942
PF03577 Peptidase_C69 14,617 5,991 1,363
PF04916 Phospholip_B 4,956 2,474 1,031
PF05742 TANGO2 14,985 8,762 2,401
PF07826 IMP_cyclohyd 3,086 1,669 216
PF09147 CarA_N 53 29 13
PF10584 Proteasome_A_N 30,171 9,043 1,516
PF12481 DUF3700 2,598 1,157 319
PF13230 GATase_4 18,706 8,261 1,415
PF13522 GATase_6 92,491 38,412 5,251
PF13537 GATase_7 76,783 42,447 10,229
CL0053 4H_Cytokine 32,411 11,800 3,293 PF00103 Hormone_1 5,776 1,560 393
PF00143 Interferon 5,502 2,279 592
PF00489 IL6 1,020 403 150
PF00714 IFN-gamma 871 261 68
PF00715 IL2 297 80 19
PF00726 IL10 2,551 844 181
PF00727 IL4 526 190 59
PF00758 EPO_TPO 1,529 626 186
PF01109 GM_CSF 215 82 23
PF01110 CNTF 735 271 75
PF01291 LIF_OSM 909 320 115
PF01415 IL7 788 192 83
PF02024 Leptin 649 217 64
PF02025 IL5 325 153 28
PF02059 IL3 108 44 20
PF02372 IL15 1,583 700 267
PF02404 SCF 1,284 420 113
PF02947 Flt3_lig 421 188 53
PF03039 IL12 680 330 100
PF03487 IL13 228 94 33
PF05337 CSF-1 1,061 436 91
PF06875 PRF 934 266 71
PF07400 IL11 584 264 98
PF14565 IL22 740 260 61
PF15036 IL34 880 340 95
PF15177 IL28A 1,054 521 134
PF15216 TSLP 149 89 57
PF16647 GCSF 638 212 51
PF16649 IL23 350 181 38
CL0054 Knottin_1 9,082 4,822 1,997 PF00304 Gamma-thionin 3,466 1,826 675
PF00451 Toxin_2 245 170 66
PF00537 Toxin_3 1,059 612 185
PF01097 Defensin_2 1,227 714 358
PF05294 Toxin_5 39 26 5
PF05453 Toxin_6 35 18 6
PF06876 SCRL 658 330 163
PF07333 SLR1-BP 1,417 671 345
PF08086 Toxin_17 34 18 2
PF09132 BmKX 15 13 9
PF10868 Defensin_like 441 211 96
PF11415 Toxin_37 163 27 4
PF14865 Macin 141 124 66
PF14866 Toxin_38 121 60 22
PF18251 Defensin_5 6 6 5
CL0055 Nucleoplasmin 258,648 34,757 10,274 PF00073 Rhv 93,514 6,011 1,324
PF00500 Late_protein_L1 6,596 1,487 175
PF00688 TGFb_propeptide 22,728 6,625 2,002
PF00718 Polyoma_coat 5,467 286 80
PF00729 Viral_coat 1,786 660 460
PF00738 Polyhedrin 644 76 15
PF00760 Cucumo_coat 2,325 579 152
PF00844 Gemini_coat 10,472 1,146 215
PF00894 Luteo_coat 3,500 268 89
PF00915 Calici_coat 41,665 1,441 363
PF00983 Tymo_coat 590 139 63
PF01318 Bromo_coat 24 8 3
PF01766 Birna_VP2 4,987 290 50
PF01787 Ilar_coat 1,184 108 36
PF01829 Peptidase_A6 25 22 11
PF02226 Pico_P1A 24,306 974 92
PF02247 Como_LCP 339 93 61
PF02248 Como_SCP 269 63 41
PF02443 Circo_capsid 5,262 286 105
PF02956 TT_ORF1 5,419 1,336 366
PF03014 SP2 8,302 167 31
PF03066 Nucleoplasmin 3,766 1,540 407
PF03115 Astro_capsid_N 4,599 591 197
PF03340 Pox_Rif 176 44 12
PF03391 Nepo_coat 930 135 72
PF03566 Peptidase_A21 85 38 28
PF03678 Adeno_hexon_C 3,252 234 34
PF03688 Nepo_coat_C 889 122 69
PF03689 Nepo_coat_N 891 124 60
PF03898 TNV_CP 64 59 54
PF04660 Nanovirus_coat 325 21 5
PF06184 Potex_coat 214 10 8
PF08435 Calici_coat_C 9,203 242 64
PF08462 Carmo_coat_C 70 4 2
PF08762 CRPV_capsid 1,793 738 516
PF08935 VP4_2 2,468 306 38
PF11175 DUF2961 7,455 4,971 1,314
PF11492 Dicistro_VP4 533 340 232
PF11729 Capsid-VNN 1,156 110 49
PF12264 Waikav_capsid_1 162 98 72
PF12944 HAV_VP 1,840 89 49
PF15414 DUF4621 39 8 6
PF16530 IHHNV_capsid 159 3 3
PF16903 Capsid_N 3,352 1,384 431
PF17800 NPL 5,382 3,159 1,386
PF18628 P2_N 412 259 116
PF21190 Bbp16 642 388 188
PF21628 Gp10-like 257 116 65
CL0056 C_Lectin 227,616 142,683 59,046 PF00059 Lectin_C 104,598 65,333 30,690
PF00193 Xlink 13,884 6,234 1,352
PF01413 C4 7,313 2,651 641
PF03440 APT 323 80 21
PF03781 FGE-sulfatase 95,779 66,626 25,324
PF05473 UL45 326 170 94
PF05689 InvE_AD 2,265 445 185
PF05966 Chordopox_A33R 157 47 24
PF06482 Endostatin 4,294 1,897 550
PF07588 DUF1554 1,274 734 376
PF07979 Intimin_C 454 71 12
PF08391 Ly49 736 305 104
PF16825 DUF5075 269 134 62
CL0057 Met_repress 237,526 128,749 37,380 PF01340 MetJ 2,228 263 23
PF01402 RHH_1 40,735 24,110 9,076
PF02697 VAPB_antitox 2,670 2,013 759
PF03693 ParD_antitoxin 13,687 7,827 1,706
PF03869 Arc 8,468 4,857 2,278
PF04221 RelB 14,850 6,560 1,954
PF05509 TraY 1,596 716 296
PF05534 HicB 11,435 7,065 2,039
PF05713 MobC 13,913 5,142 2,198
PF07181 VirC2 101 42 23
PF07328 VirD1 110 53 19
PF07362 CcdA 5,252 2,736 889
PF07704 PSK_trans_fac 3,890 2,475 579
PF07764 Omega_Repress 268 26 17
PF07878 RHH_5 2,265 1,551 824
PF08681 DUF1778 10,271 5,452 1,734
PF08870 DndE 1,755 1,104 192
PF08972 DUF1902 1,223 868 373
PF09274 ParG 1,025 467 244
PF09386 ParD 649 380 126
PF09957 VapB_antitoxin 9,219 6,108 1,323
PF10723 RepB-RCR_reg 1,068 243 100
PF10784 Plasmid_stab_B 1,150 177 69
PF10802 DUF2540 50 25 16
PF10884 DUF2683 1,386 996 291
PF11020 DUF2610 230 124 64
PF11423 Repressor_Mnt 186 44 12
PF11903 ParD_like 4,969 2,373 413
PF12441 CopG_antitoxin 4,844 3,514 944
PF12651 RHH_3 2,308 1,383 755
PF13062 DUF3924 199 12 6
PF13132 DUF3950 765 137 29
PF13467 RHH_4 9,323 4,902 810
PF14384 BrnA_antitoxin 11,187 7,039 1,882
PF15919 HicB_lk_antitox 24,773 15,230 3,211
PF15970 HicB-like_2 307 134 26
PF16762 RHH_6 594 267 79
PF16777 RHH_7 652 37 17
PF17206 SeqA_N 2,386 661 79
PF17341 DUF5371 186 102 25
PF17414 MatP_C 1,771 265 30
PF17723 RHH_8 1,784 1,014 180
PF18064 ParB_C 302 214 99
PF19514 MobC_2 4,345 1,275 355
PF19807 DUF6290 2,784 1,597 619
PF19839 RHH_9 1,146 629 111
PF19891 DUF6364 3,555 2,736 903
PF20605 Antitox_RHH 1,011 614 289
PF21217 PaaA2 1,980 903 206
PF21432 56B_RHH 115 83 58
PF21748 UPF0150 3,666 2,450 509
PF21775 PutA_1st 3,982 617 74
CL0059 6_Hairpin 509,649 282,051 75,261 PF00432 Prenyltrans 20,398 12,246 4,421
PF00723 Glyco_hydro_15 40,139 19,649 3,194
PF00759 Glyco_hydro_9 22,147 12,950 3,921
PF01122 Cobalamin_bind 2,328 1,333 389
PF01204 Trehalase 19,125 10,054 3,067
PF01270 Glyco_hydro_8 9,005 4,416 1,304
PF01397 Terpene_synth 14,731 8,045 2,808
PF01532 Glyco_hydro_47 28,736 13,599 3,913
PF02011 Glyco_hydro_48 2,314 1,070 199
PF03200 Glyco_hydro_63 9,970 5,538 1,253
PF03632 Glyco_hydro_65m 18,793 10,126 1,905
PF03663 Glyco_hydro_76 15,696 8,537 2,065
PF04685 DUF608 7,862 4,460 1,319
PF04850 Baculo_E66 227 87 24
PF05147 LANC_like 15,085 9,049 3,986
PF05426 Alginate_lyase 13,517 7,460 2,457
PF06202 GDE_C 16,108 9,576 2,458
PF06662 C5-epim_C 2,964 1,554 814
PF06824 Glyco_hydro_125 8,446 3,930 691
PF06917 Pectate_lyase_2 616 341 148
PF07221 GlcNAc_2-epim 17,396 8,799 1,938
PF07470 Glyco_hydro_88 25,444 13,626 2,791
PF07678 TED_complement 27,123 13,966 4,523
PF07944 Glyco_hydro_127 22,350 13,675 3,089
PF07971 Glyco_hydro_92 30,107 15,498 2,808
PF08124 Lyase_8_N 4,860 2,771 991
PF08760 DUF1793 5,226 3,070 673
PF09093 Lyase_catalyt 1,299 582 242
PF09492 Pec_lyase 3,127 2,169 628
PF10022 DUF2264 7,857 4,257 716
PF10091 Glycoamylase 13,254 8,375 1,630
PF11329 DUF3131 2,392 1,520 482
PF12899 Glyco_hydro_100 5,242 2,444 475
PF13243 SQHop_cyclase_C 20,085 11,135 2,777
PF13249 SQHop_cyclase_N 15,680 7,887 1,367
PF16332 DUF4962 2,799 1,729 747
PF16889 Hepar_II_III_N 7,531 5,539 2,664
PF17167 Glyco_hydro_36 13,234 8,273 1,828
PF17389 Bac_rhamnosid6H 29,386 19,434 5,609
PF17652 Glyco_hydro81C 5,770 3,477 1,207
PF18566 Ldi 1,219 853 327
PF21346 PcRGLX_3rd 2,536 1,347 283
CL0060 DNA_clamp 74,505 32,747 9,074 PF00705 PCNA_N 9,237 4,099 1,107
PF00712 DNA_pol3_beta 46,792 19,366 4,019
PF02144 Rad1 3,782 1,807 652
PF02282 Herpes_UL42 293 42 23
PF02747 PCNA_C 8,246 3,664 943
PF02767 DNA_pol3_beta_2 47,914 20,168 4,211
PF02768 DNA_pol3_beta_3 46,701 19,360 4,029
PF02916 DNA_PPF 1,433 193 56
PF03325 Herpes_PAP 100 19 3
PF04005 Hus1 3,975 1,866 708
PF04139 Rad9 4,480 2,403 868
PF04929 Herpes_DNAp_acc 90 32 19
PF09116 gp45-slide_C 797 271 99
CL0061 PLP_aminotran 1,727,587 832,586 120,033 PF00155 Aminotran_1_2 583,461 270,467 40,880
PF00202 Aminotran_3 284,285 129,456 16,239
PF00266 Aminotran_5 290,731 150,781 21,605
PF00282 Pyridoxal_deC 75,570 34,966 6,481
PF00464 SHMT 70,856 27,513 2,864
PF01041 DegT_DnrJ_EryC1 112,817 74,972 13,646
PF01053 Cys_Met_Meta_PP 140,377 62,194 6,946
PF01212 Beta_elim_lyase 51,162 27,112 3,316
PF01276 OKR_DC_1 27,605 9,907 1,804
PF02347 GDC-P 49,348 24,398 2,490
PF03841 SelA 19,812 9,926 1,784
PF04864 Alliinase_C 2,221 1,168 402
PF05889 SepSecS 2,837 1,333 414
PF06338 ComK 2,840 1,483 750
PF06838 Met_gamma_lyase 7,538 3,598 368
PF12897 Asp_aminotransf 5,036 2,481 214
PF21391 tyr_de_CO2_C 1,045 492 139
PF21478 GcvP2_C 40,906 18,389 952
CL0062 APC 1,169,980 493,257 96,835 PF00209 SNF 75,367 32,015 7,600
PF00324 AA_permease 122,655 42,072 8,537
PF00474 SSF 149,128 71,330 13,093
PF00860 Xan_ur_permease 99,804 32,661 4,340
PF00916 Sulfate_transp 98,502 47,471 9,040
PF00955 HCO3_cotransp 28,595 11,911 2,104
PF01235 Na_Ala_symp 40,078 16,558 2,080
PF01490 Aa_trans 81,388 37,652 12,255
PF01566 Nramp 49,439 23,007 3,637
PF02028 BCCT 32,694 13,904 2,041
PF02133 Transp_cyt_pur 49,358 19,756 3,388
PF02554 CstA 24,297 8,920 990
PF02705 K_trans 30,714 13,290 2,464
PF03222 Trp_Tyr_perm 16,784 4,545 1,446
PF03594 BenE 12,194 4,441 596
PF03845 Spore_permease 16,239 10,019 3,986
PF05525 Branch_AA_trans 15,219 4,867 888
PF11840 DUF3360 1,044 257 42
PF13520 AA_permease_2 221,796 96,550 18,501
PF13906 AA_permease_C 14,612 5,923 1,401
PF16983 MFS_MOT1 3,832 2,285 561
CL0063 NADP_Rossmann 12,738,180 6,537,450 1,266,402 PF00044 Gp_dh_N 89,239 30,280 2,136
PF00056 Ldh_1_N 79,547 26,011 3,052
PF00070 Pyr_redox 1,720 858 595
PF00091 Tubulin 138,789 43,490 7,659
PF00106 adh_short 781,288 425,588 93,059
PF00107 ADH_zinc_N 473,560 221,022 30,914
PF00145 DNA_methylase 70,724 43,340 12,207
PF00185 OTCace 103,334 42,704 3,021
PF00205 TPP_enzyme_M 157,603 66,392 7,279
PF00208 ELFV_dehydrog 73,777 32,467 3,318
PF00289 Biotin_carb_N 120,917 50,971 4,238
PF00291 PALP 347,453 155,741 16,777
PF00389 2-Hacid_dh 194,815 95,211 13,733
PF00398 RrnaAD 63,764 32,932 7,092
PF00455 DeoRC 81,942 30,408 5,750
PF00479 G6PD_N 46,941 18,337 2,298
PF00670 AdoHcyase_NAD 46,273 16,737 1,236
PF00732 GMC_oxred_N 127,495 66,463 12,667
PF00743 FMO-like 68,308 36,639 8,126
PF00766 ETF_alpha 54,008 24,411 2,777
PF00890 FAD_binding_2 163,125 74,670 13,455
PF00891 Methyltransf_2 46,956 28,182 8,685
PF00899 ThiF 125,073 61,339 13,160
PF00996 GDI 11,362 4,474 1,333
PF01008 IF-2B 43,405 22,858 4,220
PF01073 3Beta_HSD 18,574 9,958 3,273
PF01113 DapB_N 51,571 25,192 2,926
PF01118 Semialdhyde_dh 101,627 43,318 3,252
PF01134 GIDA 56,930 27,255 2,752
PF01135 PCMT 59,553 34,075 6,218
PF01144 CoA_trans 85,555 34,920 2,861
PF01170 UPF0020 39,158 19,678 5,220
PF01175 Urocanase 24,621 9,063 405
PF01182 Glucosamine_iso 57,303 28,242 5,108
PF01189 Methyltr_RsmB-F 81,085 42,018 9,677
PF01209 Ubie_methyltran 47,092 23,291 4,316
PF01210 NAD_Gly3P_dh_N 55,043 25,774 3,512
PF01225 Mur_ligase 137,481 71,701 11,285
PF01232 Mannitol_dh 31,054 12,977 1,614
PF01234 NNMT_PNMT_TEMT 3,091 1,844 690
PF01262 AlaDh_PNT_C 62,671 28,270 2,477
PF01266 DAO 336,357 166,427 33,496
PF01269 Fibrillarin 7,560 3,636 744
PF01358 PARP_regulatory 464 230 131
PF01370 Epimerase 450,400 261,987 50,483
PF01408 GFO_IDH_MocA 338,376 195,628 34,455
PF01488 Shikimate_DH 65,300 33,492 6,461
PF01494 FAD_binding_3 267,421 149,288 30,766
PF01555 N6_N4_Mtase 86,466 55,412 13,853
PF01564 Spermine_synth 52,822 28,647 8,236
PF01593 Amino_oxidase 182,329 102,943 24,346
PF01596 Methyltransf_3 43,041 22,296 4,292
PF01728 FtsJ 80,888 35,202 6,255
PF01739 CheR 47,065 28,043 7,312
PF01795 Methyltransf_5 50,878 26,476 3,711
PF01812 5-FTHF_cyc-lig 47,238 27,095 7,846
PF01820 Dala_Dala_lig_N 50,790 24,603 3,100
PF01861 BpsA_C 1,892 1,229 417
PF01916 DS 17,763 8,587 1,221
PF01946 Thi4 9,561 3,979 692
PF02005 TRM 9,849 5,085 1,590
PF02006 PPS_PS 2,370 1,352 128
PF02056 Glyco_hydro_4 22,584 9,424 1,195
PF02078 Synapsin 3,494 1,263 315
PF02086 MethyltransfD12 30,226 16,692 4,272
PF02146 SIR2 65,086 35,332 6,569
PF02153 PDH_N 41,291 20,907 3,723
PF02233 PNTB 28,640 11,306 1,280
PF02254 TrkA_N 123,808 60,186 11,720
PF02353 CMAS 49,315 24,867 3,976
PF02384 N6_Mtase 80,802 48,643 12,751
PF02390 Methyltransf_4 43,756 22,013 3,788
PF02423 OCD_Mu_crystall 38,423 21,436 4,137
PF02475 Met_10 14,561 8,528 2,978
PF02527 GidB 42,022 22,999 5,075
PF02550 AcetylCoA_hydro 21,960 10,280 1,120
PF02552 CO_dh 1,419 796 151
PF02558 ApbA 53,788 29,351 6,930
PF02571 CbiJ 13,421 7,027 1,250
PF02589 LUD_dom 38,907 20,233 3,200
PF02593 DUF166 1,498 1,038 265
PF02629 CoA_binding 65,545 23,276 2,336
PF02636 Methyltransf_28 23,630 13,703 3,170
PF02670 DXP_reductoisom 38,655 19,615 1,831
PF02719 Polysacc_synt_2 40,267 23,619 4,069
PF02737 3HCDH_N 121,023 56,332 7,375
PF02826 2-Hacid_dh_C 235,737 117,772 19,381
PF02844 GARS_N 49,002 23,375 2,154
PF02882 THF_DHG_CYH_C 63,191 28,457 3,255
PF02951 GSH-S_N 17,260 7,061 624
PF03059 NAS 2,466 1,293 465
PF03141 Methyltransf_29 13,312 5,831 1,383
PF03199 GSH_synthase 5,408 2,572 723
PF03269 DUF268 1,565 1,255 596
PF03275 GLF 12,689 5,838 563
PF03291 mRNA_G-N7_MeTrfase 5,838 2,928 1,124
PF03341 Pox_mRNA-cap 140 35 10
PF03435 Sacchrp_dh_NADP 50,794 25,810 4,706
PF03446 NAD_binding_2 147,407 69,818 10,314
PF03447 NAD_binding_3 59,239 25,799 3,456
PF03486 HI0933_like 42,049 23,368 3,908
PF03492 Methyltransf_7 9,558 5,446 2,042
PF03514 GRAS 20,134 9,313 2,581
PF03602 Cons_hypoth95 46,061 25,993 5,186
PF03686 UPF0146 919 595 131
PF03721 UDPG_MGDP_dh_N 93,876 50,745 5,382
PF03807 F420_oxidored 87,984 46,070 8,453
PF03808 Glyco_tran_WecG 23,834 14,583 4,130
PF03848 TehB 4,725 2,217 869
PF03853 YjeF_N 45,805 27,253 6,453
PF03917 GSH_synth_ATP 5,972 2,987 1,016
PF03949 Malic_M 67,150 25,483 2,327
PF04016 DUF364 4,510 3,195 1,005
PF04072 LCM 29,370 15,315 3,954
PF04127 DFP 47,907 24,547 3,215
PF04198 Sugar-bind 24,851 9,581 2,157
PF04223 CitF 5,203 1,839 234
PF04321 RmlD_sub_bind 52,827 33,152 7,460
PF04378 RsmJ 11,991 4,802 713
PF04445 SAM_MT 9,976 4,285 1,117
PF04536 TPM_phosphatase 35,680 21,314 5,595
PF04672 Methyltransf_19 17,463 9,681 1,552
PF04723 GRDA 1,645 653 73
PF04816 TrmK 5,380 2,321 489
PF04820 Trp_halogenase 16,279 10,610 2,485
PF04989 RMNT_CmcI 3,039 1,953 545
PF05050 Methyltransf_21 46,876 35,872 22,120
PF05059 Orbi_VP4 911 86 28
PF05063 MT-A70 12,455 6,741 2,091
PF05088 Bac_GDH_CD 14,022 6,842 1,427
PF05148 Methyltransf_8 4,001 2,333 883
PF05175 MTS 119,384 63,506 14,213
PF05185 PRMT5 4,403 2,075 689
PF05206 TRM13 2,745 1,462 670
PF05219 DREV 1,880 844 381
PF05221 AdoHcyase 48,381 18,120 1,560
PF05222 AlaDh_PNT_N 66,200 30,515 2,407
PF05368 NmrA 65,526 36,925 9,267
PF05401 NodS 4,028 2,181 471
PF05430 Methyltransf_30 16,167 8,803 1,777
PF05575 V_cholerae_RfbT 40 16 14
PF05711 TylF 6,939 4,859 2,257
PF05724 TPMT 13,073 8,023 2,096
PF05834 Lycopene_cycl 9,612 6,463 2,159
PF05891 Methyltransf_PK 4,947 2,306 705
PF05958 tRNA_U5-meth_tr 60,539 28,639 5,765
PF05971 Methyltransf_10 10,117 4,647 1,194
PF06026 Rib_5-P_isom_A 28,874 12,795 1,733
PF06039 Mqo 13,206 4,411 404
PF06080 DUF938 8,099 5,201 916
PF06100 MCRA 6,231 2,357 421
PF06325 PrmA 58,115 29,022 8,140
PF06460 CoV_Methyltr_2 5,340 344 66
PF06471 CoV_ExoN 6,143 367 59
PF06690 HcgC 122 72 21
PF06849 DUF1246 3,487 1,728 170
PF06859 Bin3 3,634 2,060 784
PF06962 rRNA_methylase 6,279 3,300 828
PF07021 MetW 10,384 5,025 911
PF07055 Eno-Rase_FAD_bd 6,089 2,142 122
PF07075 NamZ_N 15,288 10,379 1,636
PF07091 FmrO 924 625 309
PF07109 Mg-por_mtran_C 2,385 1,298 102
PF07156 Prenylcys_lyase 4,300 2,101 718
PF07279 DUF1442 1,709 817 210
PF07669 Eco57I 11,434 8,391 3,049
PF07757 AdoMet_MTase 2,791 1,646 470
PF07942 CARME 5,208 2,762 979
PF07985 SRR1 5,199 3,294 1,756
PF07991 IlvN 42,077 12,135 904
PF07992 Pyr_redox_2 615,458 292,829 42,855
PF07993 NAD_binding_4 47,632 27,495 10,053
PF07994 NAD_binding_5 10,198 4,535 637
PF08003 Methyltransf_9 8,774 3,421 736
PF08123 DOT1 6,624 4,109 2,024
PF08241 Methyltransf_11 309,533 194,386 67,877
PF08242 Methyltransf_12 54,566 32,566 13,035
PF08484 Methyltransf_14 10,546 7,024 1,581
PF08485 Polysacc_syn_2C 4,433 2,303 81
PF08491 SE 5,498 2,557 692
PF08643 DUF1776 1,262 645 173
PF08659 KR 63,506 43,187 18,357
PF08704 GCD14 15,249 7,180 1,384
PF08732 HIM1 1,197 714 235
PF09243 Rsm22 7,072 4,130 1,442
PF09445 Methyltransf_15 5,855 3,520 1,480
PF10017 Methyltransf_33 15,931 9,586 1,979
PF10128 OpcA_G6PD_assem 7,418 3,443 570
PF10237 N6-adenineMlase 4,695 2,370 775
PF10294 Methyltransf_16 34,617 20,351 8,039
PF10354 BMT5-like 5,487 3,498 1,630
PF10644 Misat_Tub_SegII 2,874 1,566 534
PF10672 Methyltrans_SAM 41,326 19,293 2,689
PF10727 Rossmann-like 9,353 5,229 1,388
PF11017 DUF2855 2,722 1,896 503
PF11312 Methyltransf_34 1,505 881 270
PF11599 AviRa 318 249 89
PF11890 DUF3410 5,867 2,088 356
PF11968 Bmt2 2,422 1,216 361
PF12147 Methyltransf_20 3,300 1,064 268
PF12241 Enoyl_reductase 6,186 2,203 138
PF12242 Eno-Rase_NADH_b 6,084 2,133 112
PF12692 Methyltransf_17 1,253 614 69
PF12831 FAD_oxidored 42,888 29,082 7,727
PF12847 Methyltransf_18 3,810 2,484 1,190
PF13241 NAD_binding_7 29,920 15,083 3,396
PF13288 DXPR_C 38,552 19,437 1,682
PF13289 SIR2_2 17,540 11,840 5,889
PF13336 AcetylCoA_hyd_C 26,253 12,826 1,598
PF13380 CoA_binding_2 62,483 36,659 6,570
PF13383 Methyltransf_22 3,290 2,111 1,074
PF13434 Lys_Orn_oxgnase 14,393 5,993 1,182
PF13450 NAD_binding_8 115,005 68,084 20,997
PF13454 NAD_binding_9 15,016 8,367 2,328
PF13460 NAD_binding_10 123,106 72,377 13,901
PF13478 XdhC_C 36,960 21,320 4,238
PF13489 Methyltransf_23 155,314 100,910 41,199
PF13561 adh_short_C2 734,666 367,668 47,939
PF13578 Methyltransf_24 31,682 22,364 10,073
PF13602 ADH_zinc_N_2 91,447 53,535 12,616
PF13649 Methyltransf_25 246,422 158,225 52,788
PF13679 Methyltransf_32 17,412 8,742 2,359
PF13727 CoA_binding_3 51,195 30,502 6,924
PF13738 Pyr_redox_3 54,002 29,666 4,580
PF13809 Tubulin_2 3,087 1,815 945
PF13847 Methyltransf_31 97,314 61,848 21,787
PF14314 Methyltrans_Mon_2nd 4,668 500 231
PF14881 Tubulin_3 3,244 1,782 570
PF16263 DUF4917 1,488 723 274
PF16363 GDP_Man_Dehyd 130,997 71,796 9,266
PF16582 TPP_enzyme_M_2 8,765 4,068 873
PF16803 DRE2_N 1,305 645 108
PF16912 Glu_dehyd_C 3,583 2,255 459
PF16924 DpaA_N 2,785 1,562 421
PF16957 Mal_decarbox_Al 3,651 736 83
PF17125 Methyltr_RsmF_N 17,783 9,070 2,071
PF17173 DUF5129 578 330 123
PF17174 DUF5130 1,675 832 104
PF17175 MOLO1 1,338 924 511
PF17396 DUF1611_N 6,173 3,767 326
PF17836 PglD_N 11,639 8,687 2,898
PF17927 Ins134_P3_kin_N 3,510 1,466 406
PF17930 LpxI_N 8,001 5,188 963
PF18030 Rimk_N 11,467 4,299 420
PF18086 PPIP5K2_N 9,066 3,524 527
PF18321 3HCDH_RFF 2,884 1,108 91
PF18706 ISPD_C 891 301 33
PF19587 DUF6094 1,577 651 269
PF20005 fvmX7 194 165 110
PF20473 MmeI_Mtase 14,243 11,890 3,231
PF20553 Methyltransf_35 310 272 155
PF20922 Anamorsin_N 1,874 776 221
PF21065 Reovirus_L2_MT1 288 42 21
PF21066 Reovirus_L2_MT2 286 40 19
PF21068 ATPgraspMvdD 2,992 1,797 474
PF21148 NSUN5_fdxn-like 4,131 2,166 634
PF21149 FAS_pseudo-KR 3,184 1,981 624
PF21162 ETFQO_UQ-bd 20,263 7,962 646
PF21360 PylC-like_N 3,892 3,021 1,087
PF21377 MurD_N 3,489 2,016 257
PF21394 Beta-ketacyl_N 5,691 3,989 2,070
PF21512 ITPK1_preATP-grasp 7 1 1
PF21570 ArgZ-like_C_2nd 3,827 2,032 190
PF21688 FAD-depend_C 18,893 9,714 784
PF21706 FCSD_central 4,432 2,907 353
PF21729 IRX15_IRX15L_GXM 2,935 1,396 394
PF21777 SDR-like 318 245 79
PF21799 MurD-like_N 28,552 15,530 2,771
CL0064 CPA_AT 457,004 216,268 43,957 PF00999 Na_H_Exchanger 193,678 94,366 20,531
PF01758 SBF 54,184 27,145 4,187
PF03547 Mem_trans 61,376 31,495 8,401
PF03601 Cons_hypoth698 23,564 11,798 1,913
PF03616 Glt_symporter 9,636 3,477 636
PF03812 KdgT 4,436 1,270 259
PF03956 Lys_export 6,870 2,714 777
PF03977 OAD_beta 17,921 5,649 568
PF04172 LrgB 19,105 6,807 1,176
PF05684 DUF819 7,306 4,274 1,050
PF05982 Sbt_1 5,004 2,761 315
PF06826 Asp-Al_Ex 12,531 4,557 905
PF06965 Na_H_antiport_1 24,147 12,772 1,910
PF11299 DUF3100 2,246 876 141
PF13593 SBF_like 15,080 6,451 1,372
CL0065 Cyclin 127,166 57,413 20,255 PF00134 Cyclin_N 75,134 33,021 11,315
PF00382 TFIIB 21,486 9,199 2,680
PF01857 RB_B 5,402 2,000 545
PF01858 RB_A 5,590 2,094 549
PF02984 Cyclin_C 36,983 15,938 5,097
PF03261 CDK5_activator 2,211 761 247
PF08613 Cyclin 14,710 7,985 3,287
PF09080 K-cyclin_vir_C 15 5 3
PF09241 Herp-Cyclin 2 2 1
PF11934 DUF3452 4,862 1,746 394
PF16899 Cyclin_C_2 5,370 2,043 517
PF18542 TFIIB_C_1 44 22 9
PF20644 Rrn7_cyclin_N 2,726 1,485 624
PF20645 Rrn7_cyclin_C 2,937 1,654 749
PF21608 V-cyclin_C 3 2 1
PF21797 CycT2-like_C 5,810 2,114 679
CL0066 Trefoil 150,745 72,870 21,876 PF00167 FGF 21,782 6,506 1,805
PF00197 Kunitz_legume 3,938 2,006 752
PF00340 IL1 4,317 1,848 593
PF00652 Ricin_B_lectin 51,562 24,733 7,543
PF02815 MIR 23,331 12,345 1,726
PF03260 Lipoprotein_11 226 109 52
PF03498 CDtoxinA 895 315 157
PF04601 DUF569 2,269 1,239 463
PF05270 AbfB 5,962 3,494 821
PF05588 Botulinum_HA-17 64 19 13
PF06229 FRG1 3,879 1,548 382
PF06268 Fascin 3,346 1,179 454
PF07468 Agglutinin 901 566 282
PF07951 Toxin_R_bind_C 191 29 14
PF08470 NTNH_C 121 15 4
PF08709 Ins145_P3_rec 12,316 7,565 946
PF09270 BTD 4,412 1,624 420
PF10467 Inhibitor_I48 175 143 77
PF14200 RicinB_lectin_2 21,113 14,133 6,178
PF15095 IL33 339 111 31
PF16850 Inhibitor_I66 724 566 339
PF18021 Agglutinin_C 185 151 99
PF18022 Lectin_C_term 19 17 12
PF21595 CCL2-like 150 110 62
CL0067 SIS 362,602 153,182 23,751 PF00318 Ribosomal_S2 70,849 23,863 3,509
PF00342 PGI 57,354 25,075 3,780
PF01380 SIS 183,828 78,024 12,405
PF10432 bact-PGI_C 7,906 5,158 1,612
PF10740 DUF2529 1,112 462 89
PF12163 HobA 893 220 45
PF13580 SIS_2 40,479 21,659 3,156
PF15698 Phosphatase 2,500 767 72
PF18353 PG_isomerase_N 98 57 7
CL0068 RIIa 15,451 7,095 2,806 PF02197 RIIa 7,474 2,958 1,003
PF05186 Dpy-30 7,975 4,137 1,803
CL0069 GFP 5,627 2,802 576 PF01353 GFP 583 284 93
PF07474 G2F 5,042 2,518 483
CL0070 ACT 389,210 159,664 21,515 PF00585 Thr_dehydrat_C 20,885 7,451 468
PF01842 ACT 160,305 64,729 8,265
PF04359 DUF493 12,666 5,727 1,205
PF08753 NikR_C 9,071 4,477 784
PF09383 NIL 28,103 9,573 906
PF10000 ACT_3 4,371 2,401 373
PF10369 ALS_ss_C 37,042 12,990 1,054
PF13291 ACT_4 53,270 21,212 2,916
PF13710 ACT_5 18,918 7,440 897
PF13740 ACT_6 25,004 10,442 1,539
PF13840 ACT_7 54,216 22,600 3,096
PF19571 ACT_8 7,632 4,922 894
PF21075 GDH_ACT1 12,314 5,659 993
PF21076 GDH_ACT2 12,202 5,568 894
PF21077 GDH_ACT3 12,591 5,793 951
PF21086 ACT_PSP_2 5,954 1,893 108
PF21389 CASTOR1_ACT-like 1,911 444 89
PF21417 TH_ACT 1,600 380 65
PF21578 117-like_vir 16 12 5
PF21699 TM1266-like 3,024 1,889 242
PF21770 MgtC_SapB_C 4,306 1,275 187
CL0071 His_phosphatase 280,083 143,230 37,910 PF00300 His_Phos_1 237,593 122,852 31,181
PF00328 His_Phos_2 42,489 20,380 6,730
CL0072 Ubiquitin 1,005,265 472,233 128,762 PF00174 Oxidored_molyb 65,059 35,212 5,199
PF00240 ubiquitin 89,418 40,968 15,933
PF00564 PB1 36,421 14,956 4,495
PF00778 DIX 8,552 3,009 826
PF00788 RA 53,009 20,930 4,039
PF00789 UBX 28,578 12,850 4,093
PF00794 PI3K_rbd 9,036 2,952 641
PF01378 IgG_binding_B 46 28 19
PF02017 CIDE-N 4,716 1,977 619
PF02192 PI3K_p85B 4,290 1,261 241
PF02196 RBD 9,590 3,563 728
PF02246 B1 9 9 6
PF02309 AUX_IAA 17,866 7,658 1,875
PF02597 ThiS 81,929 46,897 10,182
PF02821 Staphylokinase 200 33 20
PF02824 TGS 107,179 42,224 4,750
PF02876 Stap_Strp_tox_C 1,003 186 92
PF02991 ATG8 11,990 4,363 1,286
PF03607 DCX 10,752 4,725 1,466
PF03658 Ub-RnfH 9,428 4,969 778
PF03671 Ufm1 1,783 865 244
PF03990 DUF348 8,844 5,255 1,523
PF04106 ATG5_UblB 3,751 1,660 512
PF04110 APG12 3,379 1,713 549
PF04663 Phenol_monoox 1,039 545 58
PF04921 XAP5 3,528 1,612 332
PF06071 YchF-GTPase_C 50,227 18,958 1,671
PF06136 SOK 2,476 1,136 386
PF06234 TmoB 394 256 51
PF06251 Caps_syn_GfcC_C 2,605 935 376
PF06458 MucBP 6,302 3,583 2,462
PF06487 SAP18 3,424 1,506 513
PF06805 Lambda_tail_I 2,897 709 133
PF08154 NLE 6,789 2,723 663
PF08783 DWNN 4,719 2,409 849
PF08817 YukD 7,814 3,972 941
PF09138 Urm1 3,550 1,816 503
PF09379 FERM_N 47,301 18,156 3,351
PF09469 Cobl 3,410 960 233
PF09479 Flg_new 14,557 10,674 8,550
PF10302 Dsc3_N 1,404 830 238
PF10531 SLBB 99,491 55,060 13,934
PF10790 DUF2604 228 71 44
PF11434 CHIPS 27 2 2
PF11470 TUG-UBL1 2,862 1,546 530
PF11543 UN_NPL4 2,867 1,108 274
PF11620 GABP-alpha 1,260 357 121
PF11973 NQRA_SLBB 7,278 3,729 335
PF11976 Rad60-SLD 12,599 6,403 2,797
PF12053 Par3_HAL_N_term 5,372 2,377 515
PF12436 USP7_ICP0_bdg 7,234 2,715 783
PF12754 Blt1 896 431 101
PF13019 Sde2_N_Ubi 3,526 1,893 586
PF13881 Rad60-SLD_2 5,246 2,500 854
PF14009 PADRE 11,176 5,808 1,738
PF14451 Ub-Mut7C 4,339 2,681 616
PF14452 Multi_ubiq 1,685 1,191 463
PF14453 ThiS-like 702 369 44
PF14454 Prok_Ub 1,457 602 146
PF14478 DUF4430 8,915 5,610 3,025
PF14533 USP7_C2 8,661 2,874 704
PF14560 Ubiquitin_2 6,389 2,950 843
PF14836 Ubiquitin_3 5,363 1,956 287
PF14847 Ras_bdg_2 1,530 685 159
PF16207 RAWUL 8,839 2,500 751
PF16511 FERM_f0 4,829 1,956 367
PF16534 ULD 3,115 945 200
PF16978 CRIM 3,699 1,380 478
PF17965 MucBP_2 1,911 1,206 849
PF17966 Muc_B2 2,650 1,747 1,268
PF18036 Ubiquitin_4 2,195 1,125 472
PF18037 Ubiquitin_5 1,334 439 128
PF18038 FERM_N_2 5,158 2,387 243
PF18124 Kindlin_2_N 4,196 1,197 203
PF18281 BILBO1_N 89 50 19
PF18382 Formin_GBD_N 3,706 1,703 389
PF18396 TBK1_ULD 2,703 830 144
PF18655 SHIRT 611 392 278
PF18877 SSSPR-51 659 440 254
PF18998 Flg_new_2 16,567 13,866 11,176
PF20147 Crinkler 6,706 5,017 3,174
PF20170 Plexin_RBD 12,594 6,012 684
PF20616 Caps_syn_GfcC_N 2,176 609 217
PF20638 ATG5_UblA 3,986 1,811 567
PF21273 SNX17-27-31_F1_FERM 2,132 609 173
PF21403 OTU1_UBXL 2,864 1,259 317
PF21573 ForC_N 5 6 1
PF21696 TECR_N 3,023 1,064 180
PF21712 ASPP1-2_RA 2,800 1,128 330
PF21801 ASPP2-like_RA 2,636 761 116
CL0073 P53-like 72,562 27,258 7,721 PF00554 RHD_DNA_bind 13,877 4,684 1,134
PF00853 Runt 5,239 1,966 595
PF00870 P53 5,601 1,930 595
PF00907 T-box 20,573 8,362 2,688
PF02864 STAT_bind 9,536 2,774 460
PF05224 NDT80_PhoG 5,365 2,696 852
PF07887 Calmodulin_bind 4,619 2,090 746
PF08527 PAD_M 2,796 998 139
PF09271 LAG1-DNAbind 4,931 1,752 502
PF09287 CEP1-DNA_bind 15 12 10
CL0074 Matrix 67,123 13,060 1,755 PF00540 Gag_p17 64,155 12,085 1,236
PF01140 Gag_MA 1,195 482 260
PF02228 Gag_p19 449 37 15
PF02337 Gag_p10 530 283 195
PF02813 Retro_M 423 92 41
PF08723 Gag_p15 365 81 9
CL0075 Defensin 8,332 3,897 1,182 PF00323 Defensin_1 345 182 69
PF00706 Toxin_4 116 49 13
PF00711 Defensin_beta 4,346 1,957 500
PF00819 Myotoxins 31 9 5
PF07936 Defensin_4 98 73 33
PF08131 Defensin_3 70 55 39
PF08189 Meleagrin 341 117 20
PF10468 Inhibitor_I68 80 58 28
PF13841 Defensin_beta_2 2,644 1,284 451
PF14862 Defensin_big 117 53 25
PF17333 DEFB136 118 56 10
PF17858 Defensin_int 2 3 2
PF17859 Pelovaterin 0 1 1
PF17860 Defensin_RK-1 5 5 4
PF17861 Laterosporulin 4 3 1
CL0077 FAD_PCMH 341,711 183,931 32,319 PF00941 FAD_binding_5 73,403 40,105 6,775
PF01565 FAD_binding_4 268,308 143,828 25,546
CL0079 Cystine-knot 88,316 27,467 8,378 PF00007 Cys_knot 11,129 4,000 1,041
PF00019 TGF_beta 34,677 11,055 3,069
PF00236 Hormone_6 1,151 333 90
PF00243 NGF 14,457 1,338 237
PF00341 PDGF 10,793 3,948 1,208
PF02035 Coagulin 3 4 1
PF03045 DAN 4,971 1,709 595
PF05463 Sclerostin 1,641 413 99
PF05806 Noggin 1,759 673 277
PF06083 IL17 5,078 2,303 870
PF16077 Spaetzle 2,527 1,652 897
PF17486 Cys_Knot_tox 101 47 23
PF17491 m_DGTX_Dc1a_b_c 2 3 3
PF17492 D_CNTX 14 13 8
CL0080 Beta-tent 163,614 86,737 14,334 PF00838 TCTP 5,264 2,384 709
PF01641 SelR 57,934 30,763 3,120
PF03226 Yippee-Mis18 13,625 5,416 1,682
PF04248 NTP_transf_9 19,406 11,511 1,497
PF04421 Mss4 1,682 978 390
PF04828 GFA 60,449 33,582 6,219
PF11648 RIG-I_C-RD 3,758 1,410 413
PF14976 FAM72 1,488 693 304
CL0081 MBD-like 167,830 80,019 26,643 PF00847 AP2 63,283 31,711 10,547
PF01429 MBD 18,301 8,715 2,824
PF02920 Integrase_DNA 2,954 714 198
PF09003 Arm-DNA-bind_1 2,373 631 185
PF10729 CedA 780 91 11
PF12167 Arm-DNA-bind_2 4,483 2,085 639
PF13356 Arm-DNA-bind_3 43,798 22,438 7,096
PF14657 Arm-DNA-bind_4 9,219 4,552 1,804
PF16564 MBDa 2,867 932 235
PF17293 Arm-DNA-bind_5 21,309 8,620 3,193
CL0082 MIF 47,521 23,115 4,703 PF01187 MIF 7,330 3,850 1,223
PF01361 Tautomerase 20,944 10,129 1,880
PF02962 CHMI 7,511 3,123 573
PF08921 DUF1904 1,304 561 121
PF14552 Tautomerase_2 7,653 3,825 500
PF14832 Tautomerase_3 2,750 1,624 442
PF21420 Tautomerase-like 45 30 11
CL0083 Omega_toxin 29,730 14,329 4,210 PF00734 CBM_1 16,631 9,272 2,683
PF02819 Toxin_9 334 199 93
PF02950 Conotoxin 2,398 980 206
PF05039 Agouti 1,837 733 168
PF05353 Atracotoxin 23 13 4
PF05374 Mu-conotoxin 17 15 15
PF05980 Toxin_7 95 30 11
PF06357 Omega-toxin 95 34 11
PF06373 CART 1,603 685 187
PF07359 LEAP-2 830 390 104
PF07473 Toxin_11 6 4 1
PF07740 Toxin_12 653 304 126
PF07945 Toxin_16 11 7 3
PF08008 Viral_cys_rich 53 44 33
PF08027 Albumin_I 118 71 17
PF08087 Toxin_18 88 53 14
PF08089 Toxin_20 139 28 7
PF08091 Toxin_21 13 14 12
PF08092 Toxin_22 152 40 17
PF08093 Toxin_23 33 14 8
PF08094 Toxin_24 2 2 2
PF08099 Toxin_27 14 11 3
PF08115 Toxin_28 9 5 3
PF08117 Toxin_30 9 8 6
PF10530 Toxin_35 458 158 63
PF11406 Tachystatin_A 3 4 4
PF11410 Antifungal_pept 236 152 74
PF11478 Tachystatin_B 1 1 1
PF11581 Argos 226 143 68
PF11703 UPF0506 236 177 110
PF15270 ACI44 6 5 4
PF16720 Albumin_I_a 310 202 46
PF16839 Antimicrobial25 225 159 75
PF16981 Chi-conotoxin 2,911 424 40
PF17983 Tryp_inh 12 9 5
PF18687 DUF5637 21 11 8
CL0084 ADP-ribosyl 119,828 66,879 24,915 PF00644 PARP 33,149 16,494 6,693
PF01129 ART 18,606 9,522 4,176
PF01375 Enterotoxin_a 1,089 745 489
PF01885 PTS_2-RNA 11,694 7,018 2,008
PF02027 RolB_RolC 450 122 68
PF02763 Diphtheria_C 42 6 6
PF02917 Pertussis_S1 725 351 218
PF03496 ADPrib_exo_Tox 7,909 4,001 2,487
PF06108 DUF952 10,368 6,589 1,356
PF07461 NADase_NGA 186 76 54
PF08808 RES 19,897 12,246 3,816
PF09009 Exotox-A_cataly 150 32 20
PF09143 AvrPphF-ORF-2 208 64 29
PF09156 Anthrax-tox_M 20 11 9
PF09475 Dot_icm_IcmQ 176 119 51
PF10386 DUF2441 653 298 158
PF12120 Arr-ms 3,110 1,835 141
PF13151 DUF3990 3,391 1,858 631
PF14021 TNT 3,363 2,188 1,062
PF14487 DarT 3,389 2,561 1,122
PF15538 Ntox46 195 112 84
PF18648 ADPRTs_Tse2 104 84 43
PF18760 ART-PolyVal 826 624 564
PF19048 SidE_mART 82 42 7
PF21641 NarE 54 45 36
CL0087 Acyl-CoA_dh 485,996 205,490 23,744 PF00441 Acyl-CoA_dh_1 427,014 179,349 19,075
PF01756 ACOX 15,902 6,858 1,478
PF03241 HpaB 11,523 5,476 704
PF08028 Acyl-CoA_dh_2 38,215 16,707 2,984
PF21263 Acyl-CoA-dh_C 6,001 2,723 266
PF21343 ACAD9-ACADV_C 4,485 1,928 433
CL0088 Alk_phosphatase 531,605 314,791 79,005 PF00245 Alk_phosphatase 27,071 14,209 3,739
PF00884 Sulfatase 254,599 152,070 42,009
PF01663 Phosphodiest 78,951 46,010 13,775
PF01676 Metalloenzyme 61,321 32,405 4,023
PF02995 DUF229 5,543 4,121 2,455
PF04185 Phosphoesterase 28,919 15,967 3,760
PF07394 DUF1501 60,034 40,569 6,308
PF08665 PglZ 8,609 4,852 1,064
PF14707 Sulfatase_C 11,343 5,596 993
PF16347 SGSH_C 9,135 6,719 3,019
CL0089 GlnB-like 164,264 76,107 14,289 PF00543 P-II 53,612 19,338 1,906
PF02641 DUF190 7,568 4,849 882
PF03091 CutA1 19,475 12,105 3,423
PF06153 CdAMP_rec 5,511 2,594 367
PF08029 HisG_C 21,081 8,824 578
PF09413 DUF2007 16,899 10,516 3,916
PF10035 DUF2179 33,175 15,329 2,518
PF10126 Nit_Regul_Hom 127 57 11
PF11582 DUF3240 1,511 808 256
PF12122 Rhomboid_N 2,894 971 301
PF12123 CBD_PlyG 816 142 38
PF16733 NRho 1,583 577 114
CL0090 Globin 133,700 63,703 13,728 PF00042 Globin 42,008 18,355 4,833
PF00502 Phycobilisome 16,540 3,803 464
PF01152 Bac_globin 26,419 15,156 2,493
PF08678 Rsbr_N 661 321 21
PF09385 HisK_N 624 228 58
PF09995 MPAB_Lcp_cat 26,169 13,970 2,576
PF11563 Protoglobin 11,920 6,887 2,221
PF14361 RsbRD_N 5,358 3,292 855
PF20302 HisK-N-like 4,007 1,706 220
CL0091 NAD_Ferredoxin 250,117 117,383 21,486 PF00175 NAD_binding_1 195,355 90,534 15,091
PF04954 SIP 23,061 11,668 1,960
PF08030 NAD_binding_6 31,459 15,086 4,421
PF14859 Colicin_M 239 117 73
CL0092 ADF 65,001 25,683 6,289 PF00241 Cofilin_ADF 25,812 10,887 3,104
PF00626 Gelsolin 39,188 14,798 3,186
CL0093 Peptidase_CD 168,370 115,808 61,581 PF00656 Peptidase_C14 69,369 44,083 22,157
PF01364 Peptidase_C25 14,610 12,320 7,222
PF01650 Peptidase_C13 13,377 6,600 2,487
PF03415 Peptidase_C11 5,503 3,960 2,443
PF03568 Peptidase_C50 4,124 2,492 1,203
PF11713 Peptidase_C80 1,041 671 383
PF12770 CHAT 50,115 39,172 22,095
PF14252 DUF4347 5,447 4,394 3,099
PF14538 Raptor_N 4,930 2,237 581
CL0094 Peptidase_ME 302,332 150,898 31,710 PF00675 Peptidase_M16 142,885 76,197 17,891
PF02664 LuxS 10,438 3,002 173
PF03410 Peptidase_M44 197 43 11
PF05193 Peptidase_M16_C 158,609 85,058 21,702
PF07973 tRNA_SAD 125,618 57,519 6,424
PF08367 M16C_assoc 10,236 5,297 1,415
PF16187 Peptidase_M16_M 15,139 6,554 2,295
PF18490 tRNA_bind_4 596 360 82
CL0095 Peptidase_ML 25,159 14,245 4,117 PF01750 HycI 16,874 9,777 3,250
PF03418 Peptidase_A25 4,227 2,186 369
PF06866 DUF1256 4,055 2,282 498
CL0096 Pept_Inhib_IE 183 119 63 PF00299 Squash 62 39 17
PF02977 CarbpepA_inh 119 80 46
CL0097 TypeIII_Chap 37,584 17,924 5,834 PF03519 Invas_SpaK 697 200 73
PF03987 Autophagy_act_C 7,548 3,702 1,406
PF05932 CesT 5,419 2,295 1,274
PF07824 Chaperone_III 437 33 17
PF10061 DUF2299 955 503 163
PF10722 YbjN 18,609 8,999 2,499
PF20446 ABC_N 3,667 2,082 372
PF21665 Type_III_SycN 244 111 50
CL0098 SPOUT 340,190 173,842 31,369 PF00588 SpoU_methylase 172,047 87,643 14,895
PF01746 tRNA_m1G_MT 51,484 25,643 3,023
PF01994 Trm56 2,645 1,519 175
PF02590 SPOUT_MTase 30,625 14,091 2,052
PF02598 Methyltrn_RNA_3 5,062 2,569 797
PF03587 EMG1 5,437 2,581 734
PF03942 DTW 13,670 6,333 1,744
PF04013 Methyltrn_RNA_2 2,476 1,494 380
PF04034 Ribo_biogen_C 6,019 3,273 812
PF04252 SFM1-like 2,024 1,083 239
PF04407 DUF531 427 241 49
PF04452 Methyltrans_RNA 45,887 25,766 6,079
PF09895 DUF2122 358 234 99
PF09936 Methyltrn_RNA_4 1,985 1,390 261
PF12105 SpoU_methylas_C 2,865 895 88
PF14419 SPOUT_MTase_2 315 211 54
CL0099 ALDH-like 574,960 248,665 31,580 PF00171 Aldedh 519,853 220,478 27,638
PF00815 Histidinol_dh 48,830 23,895 2,695
PF05893 LuxC 6,032 4,143 1,197
PF07368 DUF1487 242 150 54
CL0100 C1q_TNF 48,939 20,969 7,271 PF00229 TNF 11,735 4,780 1,596
PF00386 C1q 34,550 14,856 5,056
PF05475 Chlam_vir 41 20 8
PF08949 PRD1_P5_C 6 2 2
PF12956 DUF3845 89 10 2
PF16532 Phage_tail_NK 250 73 31
PF18573 BclA_C 2,132 1,200 573
PF21592 Bc2l-C_N 129 29 6
CL0101 PELOTA 141,602 61,672 12,563 PF01248 Ribosomal_L7Ae 45,931 18,519 4,641
PF03465 eRF1_3 15,457 6,320 1,519
PF04705 TSNR_N 207 149 62
PF05025 RbsD_FucU 15,948 6,423 720
PF08032 SpoU_sub_bind 59,663 28,030 5,212
PF08228 RNase_P_pop3 871 603 289
PF15608 PELOTA_1 3,518 1,629 136
CL0103 Gal_mutarotase 403,645 214,181 51,377 PF01179 Cu_amine_oxid 17,900 8,551 1,923
PF01263 Aldose_epim 70,931 35,826 8,408
PF02278 Lyase_8 6,294 3,457 1,303
PF02929 Bgal_small_N 21,354 10,854 2,642
PF03512 Glyco_hydro_52 501 325 84
PF03636 Glyco_hydro_65N 16,389 8,845 1,377
PF03639 Glyco_hydro_81 3,746 2,167 741
PF04349 MdoG 10,539 3,750 642
PF06045 Rhamnogal_lyase 2,834 1,514 440
PF06165 Glyco_transf_36 11,961 7,557 1,760
PF07748 Glyco_hydro_38C 29,725 16,147 4,560
PF07940 Hepar_II_III 24,117 16,570 6,804
PF09095 AmyA-gluTrfs_C 2,329 1,790 676
PF09137 Glucodextran_N 2,709 1,528 287
PF09284 RhgB_N 1,852 869 143
PF12215 Glyco_hydr_116N 7,322 4,095 1,243
PF13802 Gal_mutarotas_2 41,820 20,036 3,956
PF14486 DUF4432 6,936 3,250 921
PF14498 Glyco_hyd_65N_2 15,279 9,560 2,327
PF14508 GH97_N 12,938 7,061 1,323
PF14614 DUF4450 833 442 116
PF14849 YidC_periplas 26,131 14,089 2,821
PF16477 DUF5054 758 472 192
PF16875 Glyco_hydro_36N 14,288 7,209 1,066
PF16923 Glyco_hydro_63N 3,800 1,843 477
PF17128 DUF5107 4,980 3,093 797
PF17168 DUF5127 5,148 3,073 689
PF17678 Glyco_hydro_92N 28,760 14,471 2,166
PF18080 Gal_mutarotas_3 1,564 657 219
PF18438 Glyco_hydro_38 1,473 451 54
PF18961 DUF5703_N 1,193 807 278
PF20938 DUF2264_C 3,306 1,568 274
PF21152 YgjK_N 1,406 505 117
PF21250 SOGP_2nd 1,163 616 134
PF21345 PcRGLX_2nd 2,925 1,698 522
PF21568 Lmo2446_N_CBM-like 142 115 10
CL0104 Glyoxalase 545,584 298,950 44,170 PF00903 Glyoxalase 400,974 218,652 32,269
PF06185 YecM 2,494 812 183
PF06983 3-dmu-9_3-mt 26,312 15,542 1,933
PF07063 DUF1338 8,692 3,457 361
PF12681 Glyoxalase_2 3,246 1,844 497
PF13468 Glyoxalase_3 13,166 8,075 2,270
PF13669 Glyoxalase_4 41,700 22,918 4,267
PF14506 CppA_N 736 139 40
PF14507 CppA_C 886 179 49
PF14696 Glyoxalase_5 14,896 5,345 393
PF18029 Glyoxalase_6 44,419 27,807 4,244
PF18711 TxDE 267 172 43
PF19581 Glyoxalase_7 4,045 1,943 312
PF20066 Glyoxalase_8 1,990 1,227 341
PF21207 GLOD4_N 1,715 357 63
PF21596 Bd2520-like_N 14 10 3
PF21701 GLOD4_C 2,227 650 151
PF21723 DUF1338_N 8,672 3,460 357
CL0105 Hybrid 3,549,933 1,702,024 349,866 PF00246 Peptidase_M14 87,564 49,739 14,475
PF00274 Glycolytic 19,482 8,326 1,240
PF00278 Orn_DAP_Arg_deC 81,249 37,935 4,457
PF00297 Ribosomal_L3 58,599 21,569 2,182
PF00358 PTS_EIIA_1 31,967 11,481 2,214
PF00364 Biotin_lipoyl 263,112 131,020 18,721
PF00529 CusB_dom_1 33,820 14,449 3,863
PF00667 FAD_binding_1 35,912 15,685 3,158
PF00677 Lum_binding 42,432 21,611 2,525
PF00842 Ala_racemase_C 52,242 27,737 5,058
PF00883 Peptidase_M17 55,721 28,129 4,803
PF00970 FAD_binding_6 120,454 54,550 8,887
PF01247 Ribosomal_L35Ae 6,072 2,793 704
PF01333 Apocytochr_F_C 14,785 1,498 154
PF01512 Complex1_51K 73,255 35,374 3,884
PF01520 Amidase_3 71,153 40,803 13,410
PF01546 Peptidase_M20 324,431 161,883 25,208
PF01551 Peptidase_M23 201,843 121,164 40,592
PF01597 GCV_H 50,838 26,003 3,251
PF01687 Flavokinase 48,363 25,753 5,662
PF01782 RimM 39,193 20,827 4,614
PF01954 AF2212-like 2,231 1,751 840
PF01980 TrmO 19,103 10,740 2,021
PF01982 CTP-dep_RFKase 3,148 1,926 599
PF02127 Peptidase_M18 20,781 9,566 1,510
PF02321 OEP 219,951 121,971 40,420
PF02749 QRPTase_N 42,010 21,443 2,187
PF02785 Biotin_carb_C 120,239 50,204 4,198
PF02843 GARS_C 48,791 23,317 2,179
PF02874 ATP-synt_ab_N 173,680 45,488 3,199
PF02952 Fucose_iso_C 9,180 4,584 481
PF03144 GTP_EFTU_D2 347,782 101,943 10,413
PF04389 Peptidase_M28 108,193 66,134 17,818
PF04410 Gar1 8,664 4,803 1,671
PF04950 RIBIOP_C 9,757 4,689 1,096
PF04952 AstE_AspA 37,008 18,213 3,993
PF05013 FGase 23,205 13,444 2,399
PF05343 Peptidase_M42 32,776 16,456 2,819
PF05450 Nicastrin 3,350 1,428 549
PF05896 NQRA 7,738 4,104 524
PF05908 Gamma_PGA_hydro 2,531 1,324 465
PF07454 SpoIIP 5,607 3,314 1,201
PF07831 PYNP_C 25,432 12,287 1,282
PF08021 FAD_binding_9 22,290 11,203 1,803
PF08022 FAD_binding_8 35,589 17,686 5,078
PF08142 AARP2CN 8,189 4,105 793
PF08408 DNA_pol_B_3 232 51 16
PF08922 DUF1905 9,976 7,243 1,300
PF09378 HAS-barrel 2,273 1,065 213
PF09891 DUF2118 235 138 69
PF10011 DUF2254 8,360 5,957 1,960
PF10994 DUF2817 3,192 2,020 676
PF11762 Arabinose_Iso_C 8,414 3,069 193
PF12700 HlyD_2 2,936 1,957 1,042
PF13375 RnfC_N 17,155 8,898 1,478
PF13437 HlyD_3 132,066 71,625 23,770
PF13533 Biotin_lipoyl_2 116,048 61,200 21,142
PF14031 D-ser_dehydrat 21,207 11,730 1,960
PF14382 ECR1_N 8,513 3,936 965
PF14505 DUF4438 1,185 774 106
PF14578 GTP_EFTU_D4 7,441 3,823 728
PF14758 NSP2_assoc 190 89 6
PF16190 E1_FCCH 8,160 3,436 733
PF16254 DUF4910 2,637 1,680 370
PF16325 Peptidase_U32_C 13,508 4,952 468
PF16538 FlgT_C 1,527 856 341
PF16572 HlyD_D4 17 17 14
PF16576 HlyD_D23 238,382 131,979 34,320
PF16580 Astro_capsid_p2 250 25 9
PF17033 Peptidase_M99 1,369 460 138
PF17767 NAPRTase_N 32,380 13,010 1,039
PF17769 PurK_C 32,089 14,483 1,332
PF17873 Rep_1B 63 4 3
PF18105 PGM1_C 1,559 993 220
PF18141 UPF1_1B_dom 3,751 1,273 234
PF18266 Ncstrn_small 2,652 1,127 445
PF18311 Rrp40_N 1,958 973 195
PF18603 LAL_C2 7,967 5,092 1,510
PF19335 HMBD 23,026 13,667 3,064
PF19501 PcRGLX_1st 3,103 1,866 637
PF21123 Dna2_Rift 1,554 702 170
PF21131 eEFSec_4th 1,669 679 231
PF21138 SMUBP-2_HCS1_1B 3,777 1,829 421
PF21143 Aquarius_N_2nd 4,298 1,533 321
PF21208 euk_SelB_III 1,721 718 250
PF21244 PurT_C 11,894 3,912 135
PF21261 RRP40_N_mamm 561 163 24
PF21440 aSelB_III 182 131 28
PF21668 RPOC_hybrid 160 65 28
CL0106 6PGD_C 650,121 308,883 43,236 PF00393 6PGD 43,641 16,376 1,454
PF00725 3HCDH 119,581 55,171 6,463
PF00984 UDPG_MGDP_dh 93,490 50,076 4,708
PF01450 IlvC 41,316 11,661 717
PF02317 Octopine_DH 5,516 3,288 953
PF03201 HMD 235 94 13
PF07479 NAD_Gly3P_dh_C 52,304 24,188 2,893
PF08125 Mannitol_dh_C 32,844 13,928 1,907
PF08546 ApbA_C 50,576 27,477 6,361
PF09130 DUF1932 5,877 3,856 746
PF10728 DUF2520 14,280 8,633 2,420
PF14748 P5CR_dimer 54,076 26,705 4,568
PF14833 NAD_binding_11 91,651 44,523 6,252
PF20463 PDH_C 39,349 19,450 3,231
PF20618 GPD_NAD_C_bact 11 12 12
PF21761 RedAm-like_C 5,359 3,450 545
CL0108 Actin_ATPase 1,181,528 558,140 125,395 PF00012 HSP70 179,411 71,996 18,717
PF00022 Actin 90,365 24,196 7,970
PF00349 Hexokinase_1 19,452 7,897 1,713
PF00370 FGGY_N 142,503 68,608 10,566
PF00480 ROK 147,171 72,790 16,425
PF00814 TsaD 102,835 54,633 10,249
PF00871 Acetate_kinase 43,952 21,504 2,739
PF01150 GDA1_CD39 19,112 8,162 2,705
PF01869 BcrAD_BadFG 39,615 24,341 5,559
PF01968 Hydantoinase_A 47,259 27,763 4,974
PF02541 Ppx-GppA 52,605 25,898 5,224
PF02543 Carbam_trans_N 15,614 9,939 2,441
PF02685 Glucokinase 16,941 8,498 2,198
PF02782 FGGY_C 139,728 65,837 9,612
PF03309 Pan_kinase 33,353 18,324 4,018
PF03630 Fumble 10,881 4,309 1,145
PF03702 AnmK 24,327 13,962 2,522
PF03727 Hexokinase_2 19,776 8,033 1,799
PF05134 T2SSL 7,175 3,708 1,351
PF05378 Hydant_A_N 44,351 25,672 4,203
PF06050 HGD-D 15,524 10,036 2,720
PF06277 EutA 3,299 1,503 383
PF06406 StbA_N 1,681 351 144
PF06723 MreB_Mbl 51,983 16,344 1,989
PF07318 DUF1464 697 494 162
PF08841 DDR 2,438 591 87
PF09989 DUF2229 10,195 6,387 1,355
PF11104 PilM_2 24,914 15,540 6,040
PF13941 MutL 4,661 3,150 697
PF14450 FtsA 37,083 15,398 2,886
PF14574 RACo_C_ter 11,248 7,688 2,142
PF17003 Actin_micro 53 40 32
PF17788 HypF_C 13,745 8,323 1,672
PF17989 ALP_N 6,214 2,672 1,100
PF21522 MreB-like_C 4,082 1,900 786
PF21523 ParM_N 1,504 215 81
PF21546 FGGY_C_2 3,058 1,890 257
CL0109 CDA 329,565 173,318 30,679 PF00383 dCMP_cyt_deam_1 132,378 73,562 11,968
PF01808 AICARFT_IMPCHas 51,512 22,386 2,112
PF02137 A_deamin 10,601 4,711 1,516
PF02634 FdhD-NarQ 27,591 14,390 2,604
PF05240 APOBEC_C 40 34 30
PF06230 LpxI_C 8,043 5,208 952
PF08210 APOBEC_N 773 292 123
PF08211 dCMP_cyt_deam_2 3,424 1,226 370
PF08973 TM1506 1,361 927 445
PF14421 LmjF365940-deam 223 150 95
PF14424 Toxin-deaminase 929 679 453
PF14427 Pput2613-deam 110 98 86
PF14428 DddA-like 558 507 358
PF14431 YwqJ-deaminase 1,743 880 310
PF14432 DYW_deaminase 32,149 16,345 4,399
PF14437 MafB19-deam 42,982 23,779 2,688
PF14439 Bd3614-deam 72 68 51
PF14440 XOO_2897-deam 1,588 1,090 235
PF14441 OTT_1508_deam 3,736 2,664 1,540
PF18744 SNAD1 264 217 127
PF18745 SNAD2 4 3 1
PF18749 SNAD3 52 41 28
PF18750 SNAD4 313 258 81
PF18752 DAAD 12 13 8
PF18767 AID 22 13 11
PF18769 APOBEC1 32 28 20
PF18771 APOBEC3 152 60 32
PF18772 APOBEC2 1,355 514 193
PF18774 APOBEC4_like 464 270 131
PF18775 APOBEC4 77 70 35
PF18778 NAD1 904 351 103
PF18782 NAD2 705 283 152
PF18785 Inv-AAD 1,935 1,083 218
PF20921 DUF1846_C 4,605 1,986 104
PF21125 MPN_2A_DUB_like 2,437 848 284
CL0110 GT-A 1,569,461 894,791 271,153 PF00483 NTP_transferase 253,811 127,712 19,400
PF00535 Glycos_transf_2 616,062 390,896 136,472
PF01128 IspD 44,510 25,008 5,130
PF01501 Glyco_transf_8 50,716 20,500 6,983
PF01644 Chitin_synth_1 8,261 3,203 659
PF01697 Glyco_transf_92 9,865 6,301 3,171
PF01704 UDPGP 18,994 8,357 2,137
PF01755 Glyco_transf_25 17,292 8,698 3,982
PF01762 Galactosyl_T 31,119 15,167 5,928
PF01793 Glyco_transf_15 7,538 4,289 1,368
PF01983 CofC 6,950 4,608 1,457
PF02348 CTP_transf_3 51,347 31,355 6,610
PF02434 Fringe 14,636 7,274 2,827
PF02485 Branch 25,796 13,272 4,277
PF02709 Glyco_transf_7C 22,829 12,754 5,124
PF03071 GNT-I 4,913 2,380 1,057
PF03142 Chitin_synth_2 14,058 6,487 1,915
PF03213 Pox_P35 518 54 23
PF03214 RGP 2,870 1,118 308
PF03314 DUF273 1,281 1,011 636
PF03360 Glyco_transf_43 7,297 2,988 968
PF03385 STELLO 1,575 966 415
PF03407 Nucleotid_trans 10,056 6,129 3,048
PF03414 Glyco_transf_6 4,560 2,040 500
PF03452 Anp1 4,634 2,218 532
PF03552 Cellulose_synt 18,108 8,431 2,160
PF04488 Gly_transf_sug 21,487 12,972 5,680
PF04646 DUF604 4,965 2,558 719
PF04765 TOD1_MUCI70 4,696 2,366 892
PF05060 MGAT2 2,482 1,113 468
PF05212 DUF707 5,090 2,387 789
PF05637 Glyco_transf_34 7,717 4,139 1,514
PF05679 CHGN 9,285 3,633 963
PF05704 Caps_synth 3,366 2,134 1,059
PF06306 CgtA 633 233 113
PF06427 UDP-g_GGTase 5,348 2,551 511
PF09258 Glyco_transf_64 9,453 3,417 1,155
PF09488 Osmo_MPGsynth 478 287 79
PF09837 DUF2064 12,071 9,167 3,027
PF10111 Glyco_tranf_2_2 1,602 1,126 563
PF11051 Mannosyl_trans3 7,039 4,151 1,773
PF11316 Rhamno_transf 1,711 1,313 583
PF11397 GlcNAc 2,059 1,415 776
PF12804 NTP_transf_3 105,400 64,247 18,381
PF12919 TcdA_TcdB 744 397 227
PF13506 Glyco_transf_21 8,914 4,942 1,650
PF13632 Glyco_trans_2_3 38,030 20,305 7,203
PF13641 Glyco_tranf_2_3 68,630 40,941 13,517
PF13704 Glyco_tranf_2_4 10,299 7,403 2,834
PF13712 Glyco_tranf_2_5 2,013 1,231 689
PF13733 Glyco_transf_7N 11,354 4,703 1,753
PF13896 Glyco_transf_49 6,854 3,667 1,721
PF16849 Glyco_transf_88 96 70 39
PF18404 Glyco_transf_24 6,022 2,823 650
PF20202 DUF6564 88 66 37
PF20691 TAGT 2,918 1,316 328
CL0111 GT-C 296,156 187,709 86,549 PF02364 Glucan_synthase 8,982 4,713 1,223
PF02366 PMT 27,179 14,386 5,072
PF02516 STT3 12,252 6,082 2,073
PF03155 Alg6_Alg8 8,191 3,950 1,301
PF03901 Glyco_transf_22 15,676 8,699 3,244
PF04188 Mannosyl_trans2 6,617 4,151 1,716
PF04602 Arabinose_trans 3,564 1,484 231
PF04922 DIE2_ALG10 3,822 2,003 785
PF05007 Mannosyl_trans 3,896 2,138 596
PF05208 ALG3 4,252 2,203 696
PF06728 PIG-U 4,325 2,032 771
PF09586 YfhO 16,636 10,489 5,535
PF09594 GT87 30,164 19,342 7,964
PF09852 DUF2079 6,357 4,408 2,175
PF09913 DUF2142 4,206 2,857 1,851
PF10034 Dpy19 4,859 1,908 674
PF10060 DUF2298 3,749 2,869 1,450
PF10131 PTPS_related 2,440 1,898 1,318
PF11028 DUF2723 11,659 7,901 3,031
PF11847 DUF3367 2,635 1,604 474
PF12250 AftA_N 1,291 668 145
PF13231 PMT_2 104,729 76,723 41,590
PF14264 Glucos_trans_II 2,317 1,252 842
PF14897 EpsG 7,383 5,113 3,593
CL0112 Yip1 52,289 26,231 9,940 PF03878 YIF1 5,103 2,160 678
PF04893 Yip1 31,356 16,415 6,196
PF06304 DUF1048 2,997 1,675 175
PF06570 DUF1129 2,623 904 322
PF06691 DUF1189 3,100 1,669 963
PF08006 DUF1700 7,104 3,416 1,613
CL0113 GT-B 1,364,148 839,067 286,311 PF00201 UDPGT 84,649 48,289 14,899
PF00343 Phosphorylase 48,879 22,136 2,970
PF00534 Glycos_transf_1 534,331 346,134 126,459
PF00852 Glyco_transf_10 17,201 9,863 4,532
PF00862 Sucrose_synth 6,676 2,604 524
PF00982 Glyco_transf_20 32,291 15,471 3,171
PF01075 Glyco_transf_9 74,080 45,195 15,250
PF01531 Glyco_transf_11 7,472 4,920 2,790
PF02350 Epimerase_2 43,143 26,315 3,985
PF02684 LpxB 28,378 15,825 3,403
PF03033 Glyco_transf_28 63,575 34,602 7,057
PF03481 Sua5_C 21,748 13,238 1,828
PF04007 DUF354 3,076 2,249 769
PF04101 Glyco_tran_28_C 74,105 42,379 10,784
PF04230 PS_pyruv_trans 29,484 19,388 9,849
PF04413 Glycos_transf_N 27,133 16,148 4,231
PF04464 Glyphos_transf 22,184 13,507 5,491
PF05159 Capsule_synth 10,653 7,289 2,668
PF05686 Glyco_transf_90 16,062 8,575 3,219
PF05693 Glycogen_syn 7,625 3,089 689
PF05830 NodZ 886 195 97
PF06258 Mito_fiss_Elm1 5,913 3,930 1,397
PF06722 EryCIII-like_C 33,385 19,704 5,198
PF06925 MGDG_synth 10,411 6,356 2,067
PF07388 A-2_8-polyST 2,462 1,388 607
PF07429 Glyco_transf_56 2,494 898 481
PF07922 Glyco_transf_52 1,040 437 244
PF08288 PIGA 4,053 1,556 283
PF08323 Glyco_transf_5 42,118 20,395 3,886
PF08660 Alg14 6,320 3,775 1,134
PF09198 T4-Gluco-transf 43 11 8
PF09314 DUF1972 3,734 2,180 385
PF10250 O-FucT 21,505 9,949 2,959
PF10933 DUF2827 1,556 557 140
PF11440 AGT 209 18 12
PF11477 PM0188 80 48 34
PF11997 DUF3492 4,379 2,350 507
PF12000 Glyco_trans_4_3 2,918 1,993 335
PF13439 Glyco_transf_4 313,920 206,177 73,173
PF13477 Glyco_trans_4_2 9,851 6,762 2,642
PF13524 Glyco_trans_1_2 24,402 17,402 8,130
PF13528 Glyco_trans_1_3 5,268 3,422 1,029
PF13579 Glyco_trans_4_4 67,158 46,236 17,831
PF13692 Glyco_trans_1_4 117,931 83,288 37,208
PF13844 Glyco_transf_41 17,856 11,254 5,409
PF15924 ALG11_N 4,246 1,989 528
PF16993 Asp1 1,235 449 238
PF16994 Glyco_trans_4_5 1,429 728 321
PF18025 FucT_N 1,506 853 324
PF19745 FUT8_N_cat 3,023 1,512 828
PF20471 DUF6716 1,830 910 178
PF20706 GT4-conflict 1,995 1,327 861
PF21036 EryCIII-like_N 4,818 2,835 776
PF21269 TreT_GT1 4,801 3,082 536
PF21374 WsaF_N 1,059 778 403
CL0114 HMG-box 111,731 48,240 17,908 PF00505 HMG_box 92,527 39,101 14,975
PF04690 YABBY 4,145 1,938 611
PF04769 MATalpha_HMGbox 1,601 613 329
PF06244 Ccdc124 3,743 1,782 420
PF06382 Protamine_like 230 174 132
PF08073 CHDNT 5,449 2,484 314
PF09011 HMG_box_2 11,292 5,101 2,174
PF14887 HMG_box_5 1,661 628 49
CL0115 Steroid_dh 105,269 63,267 18,318 PF01222 ERG4_ERG24 10,796 4,858 1,249
PF02544 Steroid_dh 15,347 7,633 2,005
PF04140 ICMT 16,119 10,071 3,411
PF04191 PEMT 36,472 24,022 8,217
PF06966 DUF1295 17,908 11,232 3,024
PF07298 NnrU 8,632 5,658 1,154
CL0116 Calycin 173,347 92,505 30,524 PF00061 Lipocalin 22,609 9,609 2,830
PF02087 Nitrophorin 79 57 30
PF02098 His_binding 3,048 2,360 1,010
PF03724 META 21,336 12,453 5,927
PF03973 Triabin 819 661 261
PF04170 NlpE 5,798 2,648 1,156
PF04755 PAP_fibrillin 7,264 4,220 1,623
PF05870 PA_decarbox 2,122 731 115
PF06206 CpeT 3,169 1,806 591
PF07137 VDE 1,306 763 315
PF07143 CrtC 8,073 5,192 1,294
PF07617 DUF1579 4,663 3,354 1,490
PF08212 Lipocalin_2 17,361 8,805 2,155
PF08622 Svf1 1,665 838 137
PF08768 THAP4_heme-bd 10,079 4,418 752
PF09148 DUF1934 6,312 3,080 1,190
PF09223 ZinT 3,493 978 190
PF09367 CpeS 2,891 1,462 223
PF09917 DUF2147 15,484 8,660 1,959
PF10285 Luciferase_cat 125 44 17
PF10703 MoaF 1,774 765 189
PF11032 ApoM 897 532 161
PF11441 MxiM 22 3 3
PF11631 DUF3255 47 12 2
PF12182 DUF3642 621 104 28
PF12204 DUF3598_N 1,641 896 225
PF12702 Lipocalin_3 654 334 158
PF12915 DUF3833 5,186 2,967 490
PF13648 Lipocalin_4 5,384 4,008 2,282
PF13761 DUF4166 4,115 2,440 659
PF13924 Lipocalin_5 4,676 3,240 1,277
PF13944 Calycin_like 879 429 258
PF14651 Lipocalin_7 3,098 1,436 371
PF14869 DUF4488 402 143 75
PF16103 DUF4822 903 312 60
PF16139 DUF4847 320 94 39
PF16270 DUF4923 772 351 172
PF16369 GH43_C 2,287 1,298 321
PF16395 DUF5004 644 462 234
PF16585 Lipocalin_8 672 298 175
PF17186 Lipocalin_9 7,688 4,902 1,153
PF17187 Svf1_C 1,712 879 170
PF17409 MoaF_C 1,646 672 143
PF18663 Pallilysin 152 124 80
PF18692 DUF5640 370 223 173
PF21053 DUF3598_C 1,215 626 136
CL0117 uPAR_Ly6_toxin 35,720 16,049 5,741 PF00021 UPAR_LY6 9,454 5,246 1,988
PF00087 Toxin_TOLIP 2,146 974 273
PF01064 Activin_recp 12,007 3,223 689
PF02988 PLA2_inh 826 399 160
PF05444 DUF753 625 428 208
PF06211 BAMBI 1,029 275 109
PF06579 Ly-6_related 996 702 368
PF08917 ecTbetaR2 1,804 505 72
PF15851 DUF4723 104 68 31
PF16975 UPAR_LY6_2 1,870 790 245
PF17064 QVR 5,589 3,852 1,851
PF19017 DUF5746 35 26 12
CL0118 Ribokinase 386,843 198,694 41,739 PF00294 PfkB 256,498 132,244 28,790
PF01256 Carb_kinase 49,894 29,522 6,673
PF02110 HK 15,767 7,213 1,163
PF04587 ADP_PFK_GK 3,074 1,438 508
PF08543 Phos_pyr_kin 61,628 28,305 4,634
CL0122 UTRA 104,977 43,919 9,832 PF01947 Rv2949c-like 2,129 1,229 381
PF04345 Chor_lyase 7,334 3,319 799
PF07702 UTRA 93,167 38,127 8,278
PF12143 PPO1_KFDV 2,343 1,244 374
CL0123 HTH 11,241,153 5,487,260 1,411,952 PF00046 Homeodomain 240,166 89,484 30,598
PF00126 HTH_1 818,204 319,958 56,204
PF00157 Pou 14,731 4,517 1,184
PF00165 HTH_AraC 2,766 2,185 1,764
PF00178 Ets 32,581 10,206 2,979
PF00196 GerE 465,358 241,301 68,267
PF00249 Myb_DNA-binding 155,490 75,515 26,500
PF00250 Forkhead 53,203 21,652 7,257
PF00292 PAX 17,695 6,623 2,051
PF00325 Crp 1,874 704 262
PF00356 LacI 256,611 114,369 22,588
PF00376 MerR 39,544 19,697 4,124
PF00392 GntR 482,688 219,418 45,800
PF00440 TetR_N 776,516 412,294 96,837
PF00447 HSF_DNA-bind 26,462 13,994 5,909
PF00486 Trans_reg_C 506,287 214,954 35,958
PF00538 Linker_histone 19,792 9,736 3,366
PF00605 IRF 9,850 3,344 811
PF00610 DEP 37,818 14,369 2,952
PF00674 DUP 535 333 191
PF01022 HTH_5 141,699 79,230 16,841
PF01035 DNA_binding_1 88,293 51,013 9,911
PF01047 MarR 158,154 80,051 22,462
PF01051 Rep3_N 12,545 5,231 2,261
PF01084 Ribosomal_S18 61,153 16,947 2,695
PF01090 Ribosomal_S19e 8,159 3,592 793
PF01285 TEA 8,431 3,005 1,018
PF01316 Arg_repressor 19,222 7,112 1,098
PF01325 Fe_dep_repress 32,943 16,820 2,914
PF01371 Trp_repressor 10,858 5,312 1,056
PF01381 HTH_3 449,853 248,665 87,870
PF01388 ARID 32,400 14,700 4,216
PF01399 PCI 62,478 20,821 5,249
PF01418 HTH_6 60,697 22,517 5,504
PF01454 MAGE 8,474 4,347 1,437
PF01475 FUR 91,177 44,534 8,781
PF01498 HTH_Tnp_Tc3_2 24,767 12,881 5,005
PF01527 HTH_Tnp_1 78,902 38,281 12,771
PF01638 HxlR 106,505 57,280 8,836
PF01710 HTH_Tnp_IS630 3,985 1,897 954
PF01726 LexA_DNA_bind 37,321 17,119 2,794
PF01873 eIF-5_eIF-2B 12,716 5,281 1,148
PF01922 SRP19 6,305 3,136 853
PF01978 TrmB 23,748 14,629 5,638
PF02001 DUF134 6,939 4,703 913
PF02002 TFIIE_alpha 7,345 3,366 1,036
PF02022 Integrase_Zn 59,040 8,064 1,105
PF02082 Rrf2 81,141 41,324 7,407
PF02186 TFIIE_beta 3,089 1,225 359
PF02257 RFX_DNA_binding 12,346 4,567 1,339
PF02270 TFIIF_beta 4,380 1,945 573
PF02295 z-alpha 1,912 854 229
PF02316 HTH_Tnp_Mu_1 2,496 1,351 499
PF02319 E2F_TDP 16,460 6,801 2,288
PF02334 RTP 424 97 19
PF02376 CUT 9,017 3,282 915
PF02437 Ski_Sno 7,693 3,052 740
PF02650 HTH_WhiA 13,447 4,600 902
PF02742 Fe_dep_repr_C 36,258 19,356 3,596
PF02787 CPSase_L_D3 68,028 23,639 1,548
PF02796 HTH_7 25,710 11,711 3,753
PF02954 HTH_8 224,836 120,125 24,633
PF02978 SRP_SPB 49,745 17,260 1,449
PF02980 FokI_dom_2 112 79 35
PF02981 FokI_D1 107 74 32
PF03221 HTH_Tnp_Tc5 24,537 15,509 8,892
PF03288 Pox_D5 5,908 2,742 1,528
PF03297 Ribosomal_S25 5,801 2,386 659
PF03333 PapB 785 288 150
PF03399 SAC3_GANP 9,966 5,429 2,311
PF03428 RP-C 4,701 2,334 552
PF03444 HrcA_DNA-bdg 9,560 4,362 884
PF03484 B5 54,078 27,508 4,958
PF03501 S10_plectin 5,671 2,226 596
PF03551 PadR 101,784 53,813 9,628
PF03634 TCP 11,609 5,329 1,619
PF03683 UPF0175 9,455 6,320 2,014
PF03882 KicB 2,056 236 38
PF03962 Mnd1 3,247 1,671 555
PF03965 Penicillinase_R 36,018 19,575 3,745
PF04079 SMC_ScpB 38,293 22,057 4,333
PF04157 EAP30 8,032 3,477 1,049
PF04182 B-block_TFIIIC 4,302 2,417 1,010
PF04218 CENP-B_N 8,504 5,042 2,968
PF04255 DUF433 26,468 18,084 4,077
PF04256 DUF434 1,502 1,092 368
PF04288 MukE 2,055 299 66
PF04297 UPF0122 7,415 3,828 999
PF04337 DUF480 7,494 3,441 504
PF04358 DsrC 11,022 5,382 654
PF04383 KilA-N 13,108 6,581 2,200
PF04408 HA2_N 54,936 23,217 4,735
PF04433 SWIRM 19,182 8,312 1,970
PF04492 Phage_rep_O 3,077 1,237 682
PF04504 DUF573 3,294 1,852 912
PF04512 Baculo_PEP_N 246 107 21
PF04539 Sigma70_r3 115,434 45,339 6,840
PF04542 Sigma70_r2 606,239 329,629 82,132
PF04545 Sigma70_r4 194,242 85,183 20,611
PF04546 Sigma70_ner 23,329 5,192 601
PF04552 Sigma54_DBD 30,999 15,230 2,818
PF04703 FaeA 1,398 704 412
PF04760 IF2_N 47,264 23,119 3,839
PF04796 RepA_C 1,869 1,011 415
PF04814 HNF-1_N 4,749 1,201 229
PF04963 Sigma54_CBD 30,658 15,053 2,801
PF04967 HTH_10 13,705 8,004 2,629
PF05043 Mga 18,033 6,781 3,431
PF05044 HPD 2,927 1,160 354
PF05066 HARE-HTH 10,120 4,882 1,416
PF05158 RNA_pol_Rpc34 4,041 1,850 716
PF05181 XPA_C 3,202 1,671 477
PF05225 HTH_psq 11,204 6,931 4,287
PF05263 DUF722 282 83 35
PF05269 Phage_CII 1,923 342 127
PF05331 DUF742 16,222 5,785 742
PF05339 DUF739 738 407 208
PF05383 La 20,235 9,127 3,218
PF05402 PqqD 20,887 13,586 6,166
PF05491 RuvB_C 43,341 16,662 701
PF05584 Sulfolobus_pRN 112 79 50
PF05645 RNA_pol_Rpc82 3,528 1,623 498
PF05732 RepL 1,682 797 423
PF05793 TFIIF_alpha 3,166 1,564 554
PF05848 CtsR 4,649 1,927 247
PF05871 ESCRT-II 3,791 1,938 604
PF05920 Homeobox_KN 41,648 15,579 5,110
PF05930 Phage_AlpA 19,277 10,986 4,464
PF06056 Terminase_5 5,823 2,024 818
PF06078 DUF937 6,622 4,157 1,175
PF06163 DUF977 1,673 327 89
PF06224 AlkZ-like 28,796 17,765 3,514
PF06322 Phage_NinH 663 65 30
PF06413 Neugrin 2,147 1,397 639
PF06504 RepC 605 171 95
PF06530 Phage_antitermQ 2,755 944 199
PF06576 DUF1133 817 139 43
PF06627 DUF1153 4,259 1,433 213
PF06806 DUF1233 1,051 270 86
PF06969 HemN_C 46,322 22,947 3,818
PF06970 RepA_N 5,304 1,647 720
PF06971 Put_DNA-bind_N 15,136 7,439 976
PF07022 Phage_CI_repr 4,977 2,808 1,441
PF07037 YfeC-like 1,821 259 54
PF07042 TrfA 942 523 223
PF07106 TBPIP 2,633 1,572 648
PF07120 DUF1376 2,014 1,271 846
PF07160 SKA1 1,651 933 361
PF07180 CaiF_GrlA 1,966 253 88
PF07278 DUF1441 1,050 285 130
PF07374 DUF1492 2,045 875 469
PF07381 DUF1495 326 196 68
PF07453 NUMOD1 2,123 1,392 843
PF07471 Phage_Nu1 1,622 635 272
PF07506 RepB 5,825 2,865 522
PF07508 Recombinase 54,398 32,213 13,423
PF07515 TraI_2_C 2,704 1,078 322
PF07574 SMC_Nse1 3,457 1,775 670
PF07638 Sigma70_ECF 10,913 9,175 3,983
PF07750 GcrA 6,246 3,410 736
PF07825 Exc 1,127 374 142
PF07848 PaaX 9,298 4,919 903
PF07900 DUF1670 973 761 477
PF08100 Dimerisation 9,672 4,990 1,326
PF08220 HTH_DeoR 91,780 34,578 7,042
PF08221 HTH_9 3,383 1,615 539
PF08222 HTH_CodY 4,371 1,369 101
PF08279 HTH_11 91,595 46,944 12,049
PF08280 HTH_Mga 1,959 671 388
PF08281 Sigma70_r4_2 424,790 247,618 66,939
PF08299 Bac_DnaA_C 48,342 22,077 4,314
PF08461 HTH_12 6,468 2,441 625
PF08535 KorB 1,554 693 314
PF08667 BetR 1,607 738 429
PF08671 SinI 2,160 1,155 492
PF08672 ANAPC2 3,236 1,458 503
PF08679 DsrD 662 405 44
PF08721 Tn7_Tnp_TnsA_C 1,660 941 363
PF08765 Mor 4,705 2,548 1,132
PF08784 RPA_C 4,420 2,273 837
PF08822 DUF1804 802 403 135
PF08839 CDT1 3,287 1,925 711
PF08849 BrxA 2,754 1,674 591
PF08876 DUF1836 5,338 2,299 606
PF08914 Myb_DNA-bind_2 2,435 1,528 819
PF08965 DUF1870 806 176 89
PF09012 FeoC 3,420 1,657 722
PF09035 Tn916-Xis 2,712 719 202
PF09039 HTH_Tnp_Mu_2 1,463 867 374
PF09048 Cro 606 278 76
PF09079 Cdc6_C 10,195 4,804 1,208
PF09105 SelB-wing_1 16 8 2
PF09106 SelB-wing_2 8,680 4,698 1,064
PF09107 SelB-wing_3 13,204 7,737 2,007
PF09111 SLIDE 6,122 2,023 376
PF09114 MotA_activ 354 28 9
PF09170 STN1_2 1,112 378 77
PF09182 PuR_N 4,130 1,366 116
PF09197 Rap1-DNA-bind 181 124 68
PF09202 Rio2_N 5,219 2,639 517
PF09278 MerR-DNA-bind 28,052 13,134 2,013
PF09339 HTH_IclR 143,449 67,724 16,755
PF09382 RQC 36,024 16,939 2,768
PF09397 FtsK_gamma 50,794 27,735 4,186
PF09402 MSC 4,161 2,181 736
PF09468 RNase_H2-Ydr279 3,624 1,802 571
PF09494 Slx4 2,598 1,570 774
PF09507 CDC27 3,477 1,945 780
PF09607 BrkDBD 1,337 894 551
PF09639 YjcQ 500 352 210
PF09645 F-112 12 9 6
PF09681 Phage_rep_org_N 3,013 1,205 613
PF09734 Tau95 4,093 2,069 827
PF09756 DDRGK 2,160 1,122 371
PF09824 ArsR 536 253 39
PF09862 DUF2089 4,120 2,597 483
PF09904 HTH_43 2,013 491 61
PF10007 DUF2250 390 241 68
PF10075 CSN8_PSD8_EIF3K 9,978 4,320 1,254
PF10078 DUF2316 589 262 89
PF10134 RPA 5,616 2,593 679
PF10264 Stork_head 2,832 918 222
PF10357 Kin17_mid 4,134 1,925 463
PF10390 ELL 3,599 1,616 575
PF10400 Vir_act_alpha_C 14,645 7,884 1,682
PF10405 BHD_3 5,095 2,717 957
PF10416 IBD 251 250 212
PF10523 BEN 9,466 3,175 1,125
PF10545 MADF_DNA_bdg 15,354 11,267 7,521
PF10557 Cullin_Nedd8 20,652 7,322 1,897
PF10668 Phage_terminase 1,223 795 299
PF10711 DUF2513 1,634 1,233 746
PF10771 DUF2582 2,721 1,352 403
PF10826 DUF2551 476 200 38
PF10975 DUF2802 3,078 1,422 516
PF11313 DUF3116 158 57 25
PF11357 Spy1 1,839 874 317
PF11362 DUF3161 217 113 60
PF11427 HTH_Tnp_Tc3_1 1,027 813 521
PF11569 Homez 1,698 481 93
PF11625 DUF3253 3,398 2,379 570
PF11972 HTH_13 1,831 1,176 231
PF11994 DUF3489 2,046 1,664 633
PF12116 SpoIIID 4,034 1,660 175
PF12181 MogR_DNAbind 360 32 8
PF12298 Bot1p 1,838 1,089 405
PF12323 HTH_OrfB_IS605 29,642 13,971 3,966
PF12324 HTH_15 657 241 104
PF12645 HTH_16 4,649 1,293 578
PF12659 Stn1_C 53 40 24
PF12728 HTH_17 120,613 69,901 29,884
PF12759 HTH_Tnp_IS1 2,580 968 301
PF12776 Myb_DNA-bind_3 14,239 9,255 5,174
PF12793 SgrR_N 6,870 1,626 435
PF12802 MarR_2 200,341 111,300 29,593
PF12824 MRP-L20 1,572 879 293
PF12833 HTH_18 621,700 324,937 99,713
PF12840 HTH_20 110,015 62,845 11,857
PF12844 HTH_19 15,548 9,502 5,519
PF12872 OST-HTH 18,677 9,872 2,440
PF12964 DUF3853 1,034 330 121
PF12976 DUF3860 587 175 32
PF13011 LZ_Tnp_IS481 5,492 2,964 973
PF13022 HTH_Tnp_1_2 877 662 406
PF13034 DUF3895 397 113 50
PF13048 DUF3908 295 50 37
PF13276 HTH_21 57,193 29,519 9,292
PF13309 HTH_22 10,485 3,633 841
PF13325 MCRS_N 2,326 935 354
PF13338 AbiEi_4 10,614 7,364 2,859
PF13384 HTH_23 26,582 16,492 10,180
PF13404 HTH_AsnC-type 61,804 26,289 5,081
PF13411 MerR_1 197,241 103,121 21,899
PF13412 HTH_24 140,635 60,602 15,766
PF13413 HTH_25 28,686 17,445 7,266
PF13443 HTH_26 47,841 26,716 8,973
PF13463 HTH_27 10,241 5,522 2,044
PF13518 HTH_28 22,013 11,374 5,910
PF13542 HTH_Tnp_ISL3 9,110 4,019 1,699
PF13545 HTH_Crp_2 121,907 65,184 17,618
PF13551 HTH_29 10,998 6,682 3,320
PF13556 HTH_30 66,091 33,589 10,040
PF13560 HTH_31 153,096 93,774 27,997
PF13565 HTH_32 19,149 11,855 4,494
PF13591 MerR_2 7,373 3,941 988
PF13592 HTH_33 10,361 6,375 2,782
PF13601 HTH_34 11,415 7,068 1,222
PF13613 HTH_Tnp_4 10,853 6,225 2,929
PF13693 HTH_35 5,713 2,245 677
PF13725 tRNA_bind_2 4,237 1,775 417
PF13730 HTH_36 15,788 9,205 5,404
PF13744 HTH_37 9,484 5,285 1,576
PF13814 Replic_Relax 4,701 3,097 1,444
PF13835 DUF4194 5,158 2,925 698
PF13837 Myb_DNA-bind_4 25,120 12,950 5,586
PF13873 Myb_DNA-bind_5 10,207 5,242 3,294
PF13921 Myb_DNA-bind_6 29,604 16,120 7,375
PF13936 HTH_38 25,405 12,494 5,135
PF14090 HTH_39 1,880 1,352 731
PF14122 YokU 664 274 45
PF14277 DUF4364 2,507 1,470 505
PF14297 Lin1244_N 2,410 1,126 789
PF14337 Abi_alpha 1,714 1,266 709
PF14338 Mrr_N 5,479 3,803 1,107
PF14394 DUF4423 2,434 1,808 1,154
PF14465 NFRKB_winged 1,481 602 156
PF14493 HTH_40 12,103 6,909 1,789
PF14502 HTH_41 1,083 441 148
PF14549 P22_Cro 1,513 736 274
PF14557 AphA_like 354 241 68
PF14590 DUF4447 94 35 5
PF14630 ORC5_C 3,783 1,800 641
PF14705 Costars 3,490 1,467 433
PF14947 HTH_45 5,316 3,428 1,479
PF15731 MqsA_antitoxin 3,284 2,064 822
PF15943 YdaS_toxin 4,002 2,224 1,020
PF15963 Myb_DNA-bind_7 4,359 2,370 1,194
PF15977 HTH_46 3,052 691 235
PF15978 TnsD 2,022 1,324 801
PF16007 DUF4777 170 135 76
PF16064 DUF4806 3,109 2,226 1,773
PF16087 DUF4817 3,807 2,809 1,543
PF16221 HTH_47 2,123 1,272 172
PF16264 SatD 2,912 1,813 626
PF16282 SANT_DAMP1_like 3,982 1,662 487
PF16365 EutK_C 743 81 13
PF16509 KORA 1,012 336 168
PF16553 PUFD 2,307 805 138
PF16557 CUTL 2,546 668 82
PF16677 GP3_package 1,404 731 435
PF16679 CDT1_C 3,588 2,066 742
PF16858 CNDH2_C 2,059 1,061 434
PF16864 Dimerisation2 13,652 8,556 2,409
PF16902 FokI_D3 112 70 31
PF17007 HTH_micro 35 28 23
PF17176 tRNA_bind_3 2,432 611 146
PF17194 AbiEi_3_N 2,558 1,268 283
PF17443 pXO2-72 116 42 16
PF17538 C_LFY_FLO 4,246 530 119
PF17726 DpnI_C 915 654 239
PF17728 BsuBI_PstI_RE_N 1,504 1,004 207
PF17761 DUF1016_N 15,754 9,558 2,570
PF17762 HTH_ParB 45,329 23,692 3,145
PF17778 BLACT_WH 13,016 7,128 1,030
PF17779 NOD2_WH 25,840 12,845 2,992
PF17782 DprA_WH 30,904 19,235 4,241
PF17783 CvfB_WH 11,931 5,205 684
PF17906 HTH_48 10,791 8,242 4,440
PF17987 PMT2_N 95 65 29
PF18010 HTH_49 243 154 29
PF18024 HTH_50 10,892 3,877 1,121
PF18090 SoPB_HTH 1,312 572 121
PF18107 HTH_ABP1_N 831 508 304
PF18114 Suv3_N 1,749 532 119
PF18118 PRC2_HTH_1 3,383 1,156 119
PF18121 TFA2_Winged_2 4,186 1,423 418
PF18137 ORC_WH_C 3,644 1,712 608
PF18196 Cdh1_DBD_1 686 377 70
PF18262 PhetRS_B1 4,509 1,747 350
PF18263 MCM6_C 3,959 1,438 315
PF18284 DNA_meth_N 2,072 262 30
PF18375 CDH1_2_SANT_HL1 3,302 1,324 201
PF18386 ROQ_II 2,665 959 232
PF18420 CSN4_RPN5_eIF3a 1,316 241 50
PF18430 DBD_HTH 1,709 205 43
PF18486 PUB_1 298 67 13
PF18503 RPN6_C_helix 3,808 977 177
PF18530 Swi6_N 51 33 6
PF18552 PheRS_DBD1 1,889 804 201
PF18553 PheRS_DBD3 3,554 1,461 249
PF18554 PheRS_DBD2 1,238 437 91
PF18558 HTH_51 2,164 1,371 518
PF18576 HTH_52 965 488 61
PF18579 Raf1_HTH 1,036 526 111
PF18580 HTH_SUN2 1,901 463 99
PF18606 HTH_53 692 305 57
PF18607 HTH_54 699 103 26
PF18622 HTH_55 360 58 5
PF18662 HTH_56 729 468 269
PF18679 HTH_57 130 91 40
PF18685 DUF5635 84 50 14
PF19121 DUF5805 415 248 37
PF19187 HTH_PafC 5,857 2,714 603
PF19368 AraR_C 16,074 7,819 788
PF19570 DUF6088 5,476 2,935 736
PF19575 HTH_58 2,957 783 251
PF19687 MARF1_LOTUS 2,024 774 157
PF19776 DUF6262 2,056 1,152 412
PF19889 DUF6362 1,015 568 200
PF20024 DUF6432 401 201 14
PF20038 HTH_59 837 441 187
PF20063 DUF6462 1,015 353 146
PF20075 DUF6471 994 758 296
PF20159 YidB 5,484 2,623 698
PF20292 MC7 319 204 87
PF20293 MC6 990 721 242
PF20295 MC8 245 148 48
PF20310 HTH_Tnp_2 1,011 597 216
PF20317 HTH_60 381 167 104
PF20432 Xre-like-HTH 9,760 5,097 1,371
PF20470 HTH_61 5,475 2,839 852
PF20514 ROXA-like_wH 9,043 3,178 426
PF20552 HTH_62 1,420 507 114
PF20575 HTH_63 680 374 160
PF20714 HTH_64 5,542 1,810 292
PF20901 Sf6_terminase 1,396 994 690
PF20987 I-TevI_DNA-bd 290 124 82
PF21084 DUF4423_like 668 417 130
PF21095 CarD_C 16,460 5,608 1,024
PF21100 MCM_C 849 531 217
PF21117 MRB1590_C 3,626 2,052 369
PF21120 MCM_WH_arc 1,095 671 223
PF21128 MCM4_WHD 2,771 886 129
PF21136 MUS81-like_WH 2,566 1,221 393
PF21179 BldD-like_C 2,652 504 110
PF21185 RecD_N 5,388 2,009 407
PF21198 ASH2L-like_WH 2,498 957 246
PF21205 Rep3_C 11,131 5,086 2,149
PF21206 Roquin_1_2-like_ROQ 2,594 921 207
PF21212 Dimerisation2-like_dom 1,636 773 94
PF21213 PriA-like_WH 2,373 399 75
PF21214 bact_SelB_WH_2nd 3,558 979 93
PF21220 RecQ-1-like_HTH 4,046 1,824 79
PF21221 B_lactamase-like_C 5,392 3,249 465
PF21224 Hen1_LCD 495 212 62
PF21227 Myb_DNA-binding_7 1,714 774 240
PF21229 TdIF1_2nd 1,298 546 205
PF21233 RIOX1_C_WH 1,523 753 300
PF21247 Fic-like_C 4,444 2,896 1,042
PF21248 SoFic-like_C 3,227 1,999 264
PF21291 CYNS_N 5,688 2,030 159
PF21296 APAF-1-like_WHD 1,731 588 159
PF21312 ORC1_wHTH 690 320 61
PF21315 FAN1_HTH 5,710 2,663 666
PF21320 HTH_65 5,864 3,505 562
PF21321 HTH_66 845 552 180
PF21392 COQ9_N 1,723 735 236
PF21434 TerS_N 2 1 1
PF21438 Sap1_N 3 3 1
PF21441 DUF3860-like 22 18 6
PF21458 SelB-wing_1_3 1,645 183 19
PF21459 INI1_DNA-bd 2,064 453 113
PF21476 PF0610-like_N 88 43 10
PF21517 HTH_Tnp_Tc3_2_like 533 436 284
PF21518 Sas-5-like_implico 16 9 5
PF21524 SAMD1_WH 4,851 2,023 461
PF21531 Rv2175c_wHTH 4,266 1,699 187
PF21552 TFC3_eWH 94 73 41
PF21559 Reb1_MybAD 109 66 39
PF21580 SelB_WHD3 8 9 3
PF21632 MOV-10_N 1,126 460 52
PF21690 MJ1010-like_2nd 345 286 54
PF21715 CggR_N 3,937 1,852 372
PF21716 dnstrm_HI1420 8,934 4,905 1,075
PF21782 PKMT_2nd 981 711 404
PF21796 Cac1_C 1,609 868 295
CL0124 Peptidase_PA 488,058 244,406 88,191 PF00089 Trypsin 196,021 112,715 47,756
PF00548 Peptidase_C3 13,763 1,397 515
PF00863 Peptidase_C4 4,657 482 132
PF00944 Peptidase_S3 2,260 156 35
PF00947 Pico_P2A 8,841 843 120
PF00949 Peptidase_S7 11,875 1,717 138
PF01577 Peptidase_S30 4,860 479 130
PF01732 Mycop_pep_DUF31 764 453 291
PF02122 Peptidase_S39 1,469 258 132
PF02395 Peptidase_S6 1,442 628 336
PF02907 Peptidase_S29 36,084 3,497 295
PF03510 Peptidase_C24 955 108 47
PF03761 DUF316 476 385 278
PF05409 Peptidase_C30 7,966 470 58
PF05416 Peptidase_C37 2,769 137 55
PF05578 Peptidase_S31 935 151 54
PF05579 Peptidase_S32 1,626 487 43
PF05580 Peptidase_S55 5,937 3,598 1,203
PF08192 Peptidase_S64 325 250 151
PF09342 DUF1986 331 219 113
PF10459 Peptidase_S46 11,187 6,612 1,494
PF12380 Peptidase_C62 22 15 11
PF12381 Peptidase_C3G 272 163 121
PF13365 Trypsin_2 184,092 110,618 35,642
PF13611 Peptidase_S76 333 36 22
PF17222 Peptidase_C107 70 20 7
CL0125 Peptidase_CA 838,886 425,790 157,266 PF00112 Peptidase_C1 67,810 37,179 15,769
PF00443 UCH 132,315 58,576 20,934
PF00648 Peptidase_C2 33,976 15,866 5,824
PF00770 Peptidase_C5 418 127 38
PF00797 Acetyltransf_2 16,525 8,362 2,268
PF00851 Peptidase_C6 5,297 510 155
PF00877 NLPC_P60 103,190 54,315 15,217
PF01088 Peptidase_C12 14,399 6,384 1,730
PF01640 Peptidase_C10 3,438 2,439 1,798
PF01707 Peptidase_C9 1,805 106 16
PF01830 Peptidase_C7 184 25 9
PF01831 Peptidase_C16 557 36 7
PF01841 Transglut_core 119,087 70,268 24,618
PF02099 Josephin 6,736 2,917 1,006
PF02338 OTU 29,024 12,792 5,015
PF02902 Peptidase_C48 42,627 25,793 14,536
PF03051 Peptidase_C1_2 12,858 5,477 989
PF03412 Peptidase_C39 28,896 15,729 4,908
PF03416 Peptidase_C54 9,429 3,618 1,282
PF03543 Peptidase_C58 965 557 339
PF03569 Peptidase_C8 28 9 2
PF03835 Rad4 4,850 2,743 950
PF04473 DUF553 953 735 557
PF04843 Herpes_teg_N 1,605 345 218
PF04970 LRAT 12,567 6,737 2,675
PF05023 Phytochelatin 3,199 1,922 860
PF05053 Menin 1,220 481 180
PF05257 CHAP 23,334 11,069 4,711
PF05379 Peptidase_C23 1,304 221 65
PF05381 Peptidase_C21 197 103 44
PF05382 Amidase_5 1,368 587 312
PF05407 Peptidase_C27 119 7 4
PF05408 Peptidase_C28 1,352 77 13
PF05410 Peptidase_C31 1,351 423 17
PF05411 Peptidase_C32 1,491 465 30
PF05412 Peptidase_C33 2,616 592 55
PF05413 Peptidase_C34 113 31 3
PF05415 Peptidase_C36 21 5 3
PF05533 Peptidase_C42 384 55 23
PF05543 Peptidase_C47 216 68 46
PF05708 Peptidase_C92 9,148 5,178 2,066
PF05903 Peptidase_C97 12,638 6,121 2,388
PF06035 Peptidase_C93 10,019 4,942 1,321
PF06672 DUF1175 1,145 407 128
PF06940 DUF1287 3,574 2,128 461
PF07313 AmiA-like 4,172 2,321 791
PF07910 Peptidase_C78 6,159 3,051 1,159
PF08715 CoV_peptidase 8,008 469 59
PF08795 DUF1796 1,994 1,134 663
PF09017 Transglut_prok 113 56 21
PF09028 Mac-1 317 194 129
PF09641 DUF2026 242 131 56
PF09764 Nt_Gln_amidase 2,450 1,380 631
PF09778 Guanylate_cyc_2 2,261 989 431
PF09916 DUF2145 1,871 908 180
PF10030 DUF2272 1,376 805 291
PF10275 Peptidase_C65 5,720 2,658 1,074
PF11814 DUF3335 2,537 1,124 240
PF12385 Peptidase_C70 2,897 1,869 1,048
PF12386 Peptidase_C71 37 27 17
PF12671 Amidase_6 5,116 3,183 1,296
PF13369 Transglut_core2 16,202 8,005 2,457
PF13423 UCH_1 3,806 1,932 575
PF13471 Transglut_core3 5,535 3,866 1,996
PF13529 Peptidase_C39_2 22,351 13,940 6,369
PF14113 Tae4 2,067 1,075 448
PF14381 EDR1 6,310 2,548 697
PF14399 BtrH_N 3,893 2,344 660
PF14822 Vasohibin 2,276 655 247
PF15499 Peptidase_C98 1,103 526 138
PF15643 Tox-PL-2 339 249 121
PF15644 Gln_amidase 1,678 1,241 747
PF15645 Tox-PLDMTX 504 98 80
PF16218 Peptidase_C101 1,841 616 221
PF16374 CIF 84 37 17
PF16683 TGase_elicitor 1,229 864 477
PF18626 Gln_deamidase_2 561 450 322
PF19049 SidE_DUB 86 44 6
PF20085 TGL 1,509 836 226
PF20900 PMT_C3 18 6 6
PF21327 GspA_C39-like 1,632 971 246
PF21435 Gln_amidase_like 30 8 7
PF21646 ACTMAP-like_C 1,136 666 307
PF21819 DUF6885 166 119 56
CL0126 Peptidase_MA 1,209,061 668,963 196,788 PF00413 Peptidase_M10 40,221 20,681 9,533
PF01400 Astacin 30,395 19,112 9,359
PF01401 Peptidase_M2 9,819 5,325 1,641
PF01421 Reprolysin 43,426 19,378 4,149
PF01431 Peptidase_M13 41,206 21,331 6,747
PF01432 Peptidase_M3 77,210 36,713 6,309
PF01433 Peptidase_M1 111,505 61,633 14,538
PF01434 Peptidase_M41 83,648 37,115 5,189
PF01435 Peptidase_M48 137,660 76,557 20,180
PF01447 Peptidase_M4 18,825 9,186 2,480
PF01457 Peptidase_M8 6,759 4,093 1,994
PF01742 Peptidase_M27 319 47 22
PF01752 Peptidase_M9 3,492 1,347 425
PF01863 YgjP-like 36,117 20,098 6,002
PF02031 Peptidase_M7 2,119 968 84
PF02074 Peptidase_M32 13,572 7,744 1,505
PF02102 Peptidase_M35 1,769 934 290
PF02128 Peptidase_M36 6,752 4,740 1,864
PF02130 YbeY 46,368 25,271 6,117
PF02163 Peptidase_M50 99,202 58,921 15,740
PF02868 Peptidase_M4_C 19,124 9,377 2,585
PF03571 Peptidase_M49 9,631 5,125 864
PF04228 Zn_peptidase 19,524 10,067 1,296
PF04298 Zn_peptidase_2 12,254 6,788 674
PF04450 BSP 4,256 2,632 930
PF05299 Peptidase_M61 12,789 8,093 1,867
PF05547 Peptidase_M6 8,469 4,804 2,029
PF05548 Peptidase_M11 1,911 1,532 1,063
PF05569 Peptidase_M56 24,082 17,787 10,407
PF05572 Peptidase_M43 13,072 8,882 3,595
PF05960 DUF885 29,647 18,542 4,062
PF06114 Peptidase_M78 44,620 27,113 10,083
PF06167 Peptidase_M90 9,841 5,395 1,210
PF06262 Zincin_1 15,975 8,205 1,233
PF07607 DUF1570 2,262 1,915 1,193
PF07737 ATLF 908 580 320
PF07998 Peptidase_M54 5,134 3,485 1,419
PF08014 MATCAP 5,860 2,586 691
PF08325 WLM 5,512 3,343 1,056
PF09471 Peptidase_M64 5,056 3,302 1,161
PF09768 Peptidase_M76 3,968 1,969 542
PF10023 Aminopep 4,885 2,887 881
PF10026 DUF2268 4,256 2,565 1,012
PF10103 Zincin_2 11,044 4,804 703
PF10263 SprT-like 21,257 10,991 3,481
PF10460 Peptidase_M30 348 231 135
PF10462 Peptidase_M66 1,424 873 512
PF10463 Peptidase_U49 213 166 105
PF11350 DUF3152 4,802 3,048 669
PF11667 DUF3267 4,505 2,692 1,215
PF12044 Metallopep 2,975 1,265 452
PF12315 DA1-like 2,786 1,371 547
PF12388 Peptidase_M57 1,670 1,296 423
PF12725 DUF3810 4,307 3,009 1,010
PF13058 DUF3920 284 28 10
PF13203 DUF2201_N 6,289 3,902 1,246
PF13398 Peptidase_M50B 8,364 4,620 1,370
PF13402 Peptidase_M60 7,039 3,076 1,401
PF13485 Peptidase_MA_2 2,299 1,799 995
PF13574 Reprolysin_2 5,629 2,452 853
PF13582 Reprolysin_3 2,533 1,834 1,313
PF13583 Reprolysin_4 6,016 4,436 2,175
PF13678 Peptidase_M85 148 30 16
PF13688 Reprolysin_5 8,828 6,076 3,610
PF13699 DUF4157 9,732 8,040 5,934
PF13933 HRXXH 884 472 129
PF14247 DUF4344 1,753 1,257 558
PF14521 Aspzincin_M35 3,075 2,027 1,015
PF14891 Peptidase_M91 1,642 1,081 712
PF15887 Peptidase_Mx 6,483 3,334 492
PF15890 Peptidase_Mx1 1,773 1,035 377
PF16313 DUF4953 10,712 6,992 1,652
PF18818 MPTase-PolyVal 10,709 5,054 1,664
PF18894 PhageMetallopep 2,568 1,473 394
PF18958 DUF5700 589 496 322
PF20565 DUF6775 601 421 134
PF20573 DUF6782 863 666 499
CL0127 ClpP_crotonase 843,324 392,818 69,152 PF00378 ECH_1 364,899 179,270 27,107
PF00574 CLP_protease 104,516 37,034 5,994
PF01039 Carboxyl_trans 145,082 54,504 5,545
PF01343 Peptidase_S49 50,804 26,283 6,889
PF01972 SDH_sah 7,267 5,138 1,455
PF03255 ACCA 31,378 12,942 769
PF03572 Peptidase_S41 111,381 64,394 18,775
PF06833 MdcE 3,570 1,194 171
PF08496 Peptidase_S49_N 6,244 2,143 310
PF16113 ECH_2 25,678 13,042 3,181
CL0128 vWA-like 454,126 241,880 73,240 PF00092 VWA 138,804 76,875 27,385
PF00362 Integrin_beta 13,333 3,996 995
PF01882 DUF58 74,130 44,233 11,104
PF03731 Ku_N 7,736 3,349 1,043
PF03850 Tfb4 3,914 1,847 661
PF04056 Ssl1 4,146 1,885 536
PF04285 DUF444 11,156 3,785 406
PF04811 Sec23_trunk 22,121 8,678 1,980
PF05762 VWA_CoxE 30,349 13,931 2,131
PF06707 DUF1194 5,141 3,343 841
PF07002 Copine 19,910 7,757 2,206
PF09967 DUF2201 5,919 3,596 1,191
PF10138 vWA-TerF-like 4,164 2,108 469
PF11265 Med25_VWA 2,611 1,203 516
PF11775 CobT_C 7,302 3,401 558
PF12194 Ste5_C 63 48 27
PF13519 VWA_2 81,619 50,087 19,261
PF13768 VWA_3 25,118 15,372 6,221
PF19997 ivWA 99 83 53
PF20782 TssR_VWA 623 234 113
CL0129 Peptidase_AA 562,711 283,131 111,826 PF00026 Asp 52,857 30,818 12,541
PF00077 RVP 373,376 159,569 53,302
PF02160 Peptidase_A3 298 168 91
PF03539 Spuma_A9PTase 442 207 138
PF05585 DUF1758 9,416 7,223 5,266
PF05618 Zn_protease 13,004 6,429 1,316
PF08284 RVP_2 26,749 22,614 13,832
PF09668 Asp_protease 6,499 2,973 1,292
PF12382 Peptidase_A2_2 11 2 1
PF12384 Peptidase_A2B 127 102 94
PF13650 Asp_protease_2 28,542 22,562 12,838
PF13975 gag-asp_proteas 23,703 16,080 8,004
PF14541 TAXi_C 25,481 13,362 4,161
PF14543 TAXi_N 26,052 13,781 4,449
PF20729 PE-PGRS_C 642 354 129
CL0130 Peptidase_AD 70,465 40,355 13,365 PF01080 Presenilin 4,842 1,953 741
PF01478 Peptidase_A24 50,628 31,834 10,544
PF04258 Peptidase_A22B 12,892 5,184 1,663
PF06550 SPP 2,106 1,392 422
CL0131 DoxD-like 141,049 82,349 18,407 PF02077 SURF4 4,154 1,511 421
PF04173 DoxD 2,189 1,310 343
PF04224 DUF417 4,898 1,937 346
PF05477 SURF2 1,729 885 366
PF05514 HR_lesion 1,410 732 243
PF06762 LMF1 7,201 3,931 1,174
PF07291 MauE 20,188 14,212 4,949
PF07681 DoxX 73,698 41,119 7,559
PF13564 DoxX_2 20,918 14,341 2,894
PF13781 DoxX_3 3,944 2,350 523
PF15111 TMEM101 717 178 74
CL0132 AbrB 91,540 49,875 12,928 PF02381 MraZ 34,606 16,317 3,217
PF04014 MazE_antitoxin 51,176 30,760 8,959
PF09612 HtrL_YibB 1,153 679 439
PF14250 AbrB-like 2,013 732 62
PF15937 PrlF_antitoxin 2,589 1,418 402
CL0133 AT14A-like 11,872 5,950 2,018 PF03087 BPS1 6,713 3,584 1,250
PF05055 DUF677 2,666 1,352 462
PF05633 ROH1-like 2,491 1,030 332
CL0135 Arrestin_N-like 53,107 23,606 8,561 PF00339 Arrestin_N 27,332 12,782 4,897
PF02752 Arrestin_C 26,216 11,904 4,375
PF03643 Vps26 8,663 2,441 664
PF04425 Bul1_N 518 381 188
PF07070 Spo0M 6,335 2,743 625
PF08737 Rgp1 3,569 1,611 547
PF13002 LDB19 1,263 631 200
CL0136 Plasmid-antitox 237,418 149,120 37,035 PF02604 PhdYeFM_antitox 58,992 35,948 8,729
PF04365 BrnT_toxin 15,849 11,187 2,135
PF05015 HigB-like_toxin 14,714 9,572 1,233
PF05016 ParE_toxin 72,607 48,191 14,666
PF05973 Gp49 23,164 14,174 3,092
PF06296 RelE 6,551 3,745 937
PF06769 YoeB_toxin 12,409 7,200 889
PF10047 DUF2281 3,948 2,832 1,097
PF10715 REGB_T4 408 30 7
PF11663 Toxin_YhaV 1,756 867 157
PF12910 PHD_like 532 384 138
PF14076 DUF4258 6,372 5,124 2,135
PF15723 MqsR_toxin 1,537 921 270
PF15738 YafQ_toxin 9,571 4,902 1,117
PF15781 ParE-like_toxin 2,115 1,474 345
PF18389 TrmO_C 7,056 2,739 312
CL0137 HAD 1,260,076 633,726 144,864 PF00702 Hydrolase 485,934 242,818 47,193
PF01368 DHH 96,022 52,327 11,888
PF02358 Trehalose_PPase 30,666 16,003 4,094
PF03031 NIF 34,886 17,037 6,316
PF03332 PMM 7,332 3,375 659
PF03690 UPF0160 6,771 3,666 951
PF03767 Acid_phosphat_B 12,825 5,920 1,758
PF05116 S6PP 8,910 4,917 1,200
PF05152 DUF705 276 156 49
PF05761 5_nucleotid 12,502 4,892 1,369
PF05822 UMPH-1 4,402 1,861 719
PF06888 Put_Phosphatase 5,084 2,555 854
PF06941 NT5C 8,912 5,190 1,665
PF08235 LNS2 9,588 4,286 1,060
PF08282 Hydrolase_3 125,179 58,486 16,612
PF08645 PNK3P 7,465 4,096 1,584
PF09419 PGP_phosphatase 3,047 1,947 707
PF09949 APP1_cat 9,845 5,833 1,589
PF11019 DUF2608 834 579 401
PF12689 Acid_PPase 3,652 2,272 836
PF12710 HAD 73,750 35,893 7,317
PF13242 Hydrolase_like 79,918 42,432 10,195
PF13246 Cation_ATPase 127,861 52,199 9,109
PF13344 Hydrolase_6 46,804 23,356 4,497
PF13419 HAD_2 165,755 94,300 29,008
PF16212 PhoLip_ATPase_C 42,318 17,134 3,353
PF21141 T6PP_C 575 367 141
CL0139 GADPH_aa-bio_dh 705,135 333,442 43,387 PF00742 Homoserine_dh 54,079 22,836 3,254
PF01658 Inos-1-P_synth 19,209 7,803 601
PF01958 Asp_DH_C 6,645 3,617 704
PF02774 Semialdhyde_dhC 84,659 35,953 2,755
PF02781 G6PD_C 48,202 18,726 2,388
PF02800 Gp_dh_C 105,794 34,175 2,922
PF02894 GFO_IDH_MocA_C 218,142 122,964 21,052
PF05173 DapB_C 44,765 21,909 2,420
PF08436 DXP_redisom_C 38,535 19,461 1,556
PF08635 ox_reductase_C 832 520 146
PF09166 Biliv-reduc_cat 947 257 50
PF09290 AcetDehyd-dimer 7,419 2,973 137
PF16490 Oxidoreduct_C 879 626 108
PF16653 Sacchrp_dh_C 30,920 14,357 2,094
PF16654 DAPDH_C 4,014 1,928 76
PF19051 GFO_IDH_MocA_C2 24,719 17,763 2,297
PF19858 OxRdtase_C 1,698 850 60
PF20171 OpcA_G6PD_C 7,349 3,399 575
PF21252 Glyco_hydro_109_C 6,329 3,415 361
CL0140 Viral_NABP 2,085 344 113 PF01623 Carla_C4 572 166 62
PF04808 CTV_P23 618 20 2
PF05515 Viral_NABP 892 162 54
CL0141 MtN3-like 67,819 35,381 10,167 PF00810 ER_lumen_recept 9,285 3,619 904
PF03083 MtN3_slv 15,971 8,384 3,018
PF03650 MPC 8,459 4,047 881
PF04193 PQ-loop 29,652 16,786 5,165
PF07578 LAB_N 4,499 2,622 386
CL0142 Membrane_trans 754,435 339,760 54,476 PF00950 ABC-3 60,096 28,189 4,250
PF01032 FecCD 123,270 54,140 7,982
PF01098 FTSW_RODA_SPOVE 101,139 50,829 9,865
PF02653 BPD_transp_2 434,294 188,795 27,586
PF05145 AbrB 11,982 5,953 1,756
PF06912 DUF1275 22,124 10,988 2,779
PF08566 Pam17 1,524 867 259
CL0143 B_Fructosidase 145,086 81,050 17,047 PF00251 Glyco_hydro_32N 33,966 17,693 4,740
PF02435 Glyco_hydro_68 2,348 892 184
PF03664 Glyco_hydro_62 3,234 1,941 307
PF04041 Glyco_hydro_130 16,708 10,480 1,612
PF04616 Glyco_hydro_43 77,356 43,764 8,156
PF06079 Apyrase 2,535 1,183 430
PF08950 DUF1861 1,012 556 124
PF13810 DUF4185 5,339 3,153 1,002
PF14517 Tachylectin 838 574 300
PF16396 DUF5005 257 184 95
PF17312 Helveticin_J 442 212 89
PF21311 Phage_RBD_prop 1,103 495 159
CL0144 Periplas_BP 763,939 354,054 85,328 PF00532 Peripla_BP_1 39,323 16,016 5,501
PF01094 ANF_receptor 97,032 42,470 14,064
PF02608 Bmp 40,331 20,348 3,492
PF04348 LppC 8,171 3,549 1,323
PF04392 ABC_sub_bind 23,886 14,602 5,345
PF12683 DUF3798 986 586 134
PF13377 Peripla_BP_3 235,496 111,647 26,160
PF13407 Peripla_BP_4 141,266 59,058 11,960
PF13433 Peripla_BP_5 14,942 4,867 605
PF13458 Peripla_BP_6 163,232 83,237 19,692
PF18610 Peripla_BP_7 451 159 13
CL0145 Golgi-transport 149,570 54,619 11,102 PF00611 FCH 38,210 14,561 2,719
PF03114 BAR 32,024 12,272 2,493
PF06456 Arfaptin 8,649 2,587 654
PF06730 FAM92 2,280 1,038 337
PF08397 IMD 10,830 3,812 733
PF09325 Vps5 12,509 4,519 1,082
PF10455 BAR_2 1,713 737 159
PF10456 BAR_3_WASP_bdg 8,519 1,561 374
PF12240 Angiomotin_C 3,338 938 185
PF13805 Pil1 3,064 1,501 427
PF16746 BAR_3 25,418 9,529 1,530
PF20400 BAR_4 3,007 1,585 449
CL0146 Herpes_glyco 559 108 52 PF03554 Herpes_UL73 480 78 37
PF05702 Herpes_UL49_5 77 30 15
CL0147 Traffic 20,503 8,953 2,732 PF03908 Sec20 4,584 2,138 751
PF05008 V-SNARE 6,274 2,636 707
PF12352 V-SNARE_C 15,106 6,331 1,756
CL0148 Viral_Gag 106,394 27,525 8,027 PF00607 Gag_p24 57,869 12,185 2,558
PF02023 SCAN 18,356 8,804 3,889
PF02093 Gag_p30 3,096 1,919 963
PF03276 Gag_spuma_N 1,493 33 12
PF19317 Gag_p24_C 74,792 14,643 2,366
PF20672 Gag_FV_central 1,577 31 13
PF20673 Gag_spuma_C 163 25 10
PF21395 Arc_capsid_dom 542 32 11
CL0149 CoA-acyltrans 327,430 184,782 62,626 PF00198 2-oxoacid_dh 117,196 60,848 8,256
PF00302 CAT 6,124 3,133 735
PF00668 Condensation 114,056 72,824 37,616
PF00755 Carn_acyltransf 22,462 9,490 3,034
PF02458 Transferase 39,849 22,823 8,360
PF03007 WS_DGAT_cat 21,775 12,097 3,155
PF07247 AATase 3,565 2,107 915
PF07428 Tri3 509 309 147
PF16911 PapA_C 2,360 1,479 594
CL0153 dUTPase 76,478 34,436 5,011 PF00692 dUTPase 68,428 31,341 4,546
PF04797 Herpes_ORF11 308 61 39
PF05784 Herpes_UL82_83 244 50 34
PF06088 TLP-20 156 78 46
PF06284 Cytomega_UL84 106 10 6
PF06501 Herpes_U55 50 13 9
PF06559 DCD 7,201 3,106 407
CL0154 C2 385,762 167,158 43,603 PF00168 C2 263,836 116,100 29,986
PF00792 PI3K_C2 13,433 4,655 984
PF03366 YEATS 10,292 4,307 1,294
PF06468 Spond_N 6,058 3,068 1,193
PF06744 IcmF_C 10,578 3,958 923
PF07162 B9-C2 5,067 2,485 983
PF07657 MNNL 6,937 2,471 594
PF08174 Anillin 6,116 2,548 698
PF10358 NT-C2 12,953 5,952 1,888
PF10409 PTEN_C2 16,534 6,837 1,653
PF11618 C2-C2_1 1,959 956 370
PF14186 Aida_C2 1,407 445 179
PF14429 DOCK-C2 24,169 10,893 1,490
PF14909 SPATA6 2,209 903 344
PF14924 DUF4497 1,073 685 317
PF15625 CC2D2AN-C2 1,730 903 326
PF15627 CEP76-C2 1,329 353 132
PF15729 CTSRT 394 169 76
PF18111 RPGR1_C 2,063 920 316
PF18695 cPLA2_C2 3,005 1,045 136
PF20305 pYEATS 345 315 243
PF21494 PKC_C2 2,934 803 129
CL0155 CBM_14_19 30,402 19,052 10,658 PF01607 CBM_14 29,960 18,721 10,476
PF03427 CBM_19 441 332 183
CL0156 Nucleocapsid 36,856 1,054 446 PF00945 Rhabdo_ncap 13,597 520 249
PF00973 Paramyxo_ncap 19,488 275 97
PF03246 Pneumo_ncap 2,604 79 27
PF05505 Ebola_NP 632 83 11
PF06407 BDV_P40 530 97 62
CL0157 Kleisin 43,234 23,182 4,637 PF02616 SMC_ScpA 36,077 19,765 3,268
PF04824 Rad21_Rec8 7,180 3,433 1,388
CL0158 GH_CE 270,430 155,687 46,308 PF01074 Glyco_hydro_38N 33,496 18,860 5,565
PF01522 Polysacc_deac_1 158,749 92,261 28,475
PF03065 Glyco_hydro_57 20,582 13,914 3,515
PF03746 LamB_YcsF 23,034 10,726 1,248
PF04748 Polysacc_deac_2 11,795 6,729 2,757
PF04794 YdjC 13,936 7,946 2,563
PF09960 DUF2194 1,000 542 289
PF10096 DUF2334 5,768 3,287 1,302
PF12979 DUF3863 159 110 19
PF14323 GxGYxYP_C 1,710 1,213 566
PF15421 Polysacc_deac_3 194 111 47
CL0159 E-set 3,002,725 1,648,051 689,057 PF00028 Cadherin 115,767 51,090 15,656
PF00041 fn3 270,367 124,274 42,681
PF00047 ig 59,101 24,701 9,974
PF00100 Zona_pellucida 29,794 14,951 5,178
PF00207 A2M 37,762 20,607 6,939
PF00287 Na_K-ATPase 7,431 3,122 994
PF00345 PapD_N 28,879 9,125 2,812
PF00630 Filamin 20,585 8,822 3,399
PF00635 Motile_Sperm 18,790 9,498 3,806
PF00703 Glyco_hydro_2 73,737 41,279 9,256
PF00801 PKD 19,081 12,710 7,954
PF00868 Transglut_N 9,672 3,563 911
PF00927 Transglut_C 9,627 3,162 750
PF00932 LTD 41,704 29,150 16,177
PF00943 Alpha_E2_glycop 3,963 212 52
PF00960 Neocarzinostat 661 450 250
PF01108 Tissue_fac 10,077 4,866 1,464
PF01345 DUF11 32,756 26,422 18,317
PF01357 Expansin_C 14,503 6,030 1,153
PF01537 Herpes_glycop_D 665 143 71
PF01567 Hanta_Gn-H 1,011 96 31
PF01688 Herpes_gI 396 58 35
PF01833 TIG 53,822 31,036 14,555
PF01835 MG2 34,390 18,704 6,581
PF01880 Desulfoferrodox 7,716 4,962 651
PF02010 REJ 7,091 4,510 2,652
PF02014 Reeler 8,768 4,518 2,151
PF02019 WIF 3,196 1,355 391
PF02115 Rho_GDI 6,627 2,749 642
PF02124 Marek_A 715 75 34
PF02368 Big_2 35,474 23,129 15,818
PF02369 Big_1 6,054 3,860 2,761
PF02440 Adeno_E3_CR1 355 66 25
PF02480 Herpes_gE 712 106 42
PF02494 HYR 11,498 7,617 5,223
PF02753 PapD_C 21,434 5,695 1,458
PF02832 Flavi_glycop_C 34,820 2,069 121
PF02883 Alpha_adaptinC2 21,283 8,182 1,089
PF02903 Alpha-amylase_N 6,930 2,552 508
PF02927 CelD_N 8,098 5,320 1,423
PF02960 K1 1,280 110 11
PF03067 LPMO_10 15,622 7,390 1,791
PF03160 Calx-beta 30,087 18,143 10,736
PF03168 LEA_2 20,614 10,925 3,818
PF03174 CHB_HEX_C 2,522 1,298 346
PF03404 Mo-co_dimer 21,421 11,086 1,823
PF03442 CBM_X2 2,355 1,512 607
PF03443 AA9 15,031 9,027 2,373
PF03504 Chlam_OMP6 72 22 9
PF03524 CagX 13,260 4,815 1,254
PF03723 Hemocyanin_C 3,215 1,945 682
PF03785 Peptidase_C25_C 1,260 1,072 659
PF03921 ICAM_N 2,489 1,361 472
PF04234 CopC 20,068 11,407 4,067
PF04379 DUF525 18,562 8,027 1,066
PF04729 ASF1_hist_chap 5,382 1,887 498
PF04775 Bile_Hydr_Trans 6,030 2,633 719
PF04881 Adeno_GP19K 217 15 6
PF05031 NEAT 3,311 1,278 633
PF05109 Herpes_gp350_A 240 9 4
PF05326 SVA 245 132 48
PF05345 He_PIG 27,428 21,768 14,905
PF05351 GMP_PDE_delta 4,643 1,640 392
PF05566 Pox_vIL-18BP 96 22 12
PF05587 Anth_Ig 3,786 1,381 224
PF05688 BIg21 2,228 416 160
PF05753 TRAP_beta 3,919 1,569 609
PF05790 C2-set 1,245 408 82
PF05963 Cytomega_US3 104 12 7
PF06016 Reovirus_L2_8th 86 15 5
PF06030 DUF916 5,099 2,680 1,163
PF06214 SLAM 341 93 18
PF06280 fn3_5 7,099 3,655 1,455
PF06312 Neurexophilin 6,326 2,285 529
PF06328 Lep_receptor_Ig 3,958 1,302 241
PF06776 IalB 11,721 6,186 1,813
PF06832 BiPBP_C 12,366 6,096 1,279
PF07092 TMEM106 2,696 906 206
PF07140 IFNGR1_D2 414 111 26
PF07198 DUF1410 138 59 46
PF07233 DUF1425 3,293 1,212 445
PF07354 Sp38 1,289 561 111
PF07495 Y_Y_Y 38,759 25,161 12,567
PF07523 Big_3 3,928 2,058 1,506
PF07532 Big_4 5,775 3,395 1,498
PF07610 DUF1573 18,415 13,130 5,928
PF07654 C1-set 81,237 29,006 7,618
PF07677 A2M_recep 16,471 8,415 2,336
PF07679 I-set 245,563 102,666 32,837
PF07686 V-set 211,650 122,618 35,283
PF07703 A2M_BRD 34,166 18,133 5,949
PF07705 CARDB 21,298 16,119 11,183
PF07711 RabGGT_insert 635 200 56
PF07718 Coatamer_beta_C 4,321 1,217 268
PF08191 LRR_adjacent 1,755 458 260
PF08204 V-set_CD47 1,556 566 173
PF08205 C2-set_2 42,218 19,106 7,155
PF08266 Cadherin_2 33,227 14,106 2,552
PF08329 ChitinaseA_N 1,610 595 203
PF08428 Rib 2,202 1,470 1,002
PF08441 Integrin_A_Ig_1 18,173 6,549 1,242
PF08481 GBS_Bsp-like 1,545 781 483
PF08522 DUF1735 5,221 2,461 1,083
PF08752 COP-gamma_platf 5,553 1,772 392
PF08758 Cadherin_pro 6,303 1,699 291
PF08770 SoxZ 7,598 4,386 656
PF08779 bCoV_NS7A 544 44 10
PF09067 EpoR_lig-bind 5,384 1,838 378
PF09085 Adhes-Ig_like 374 211 52
PF09087 Cyc-maltodext_N 3,780 2,399 329
PF09099 Qn_am_d_aIII 1,032 578 231
PF09100 Qn_am_d_aIV 921 455 99
PF09118 GO-like_E_set 11,118 6,467 1,689
PF09134 Invasin_D3 2,795 1,814 1,330
PF09136 Glucodextran_B 7,134 5,455 3,489
PF09191 CD4-extracel 501 197 80
PF09238 IL4Ra_N 867 327 93
PF09240 IL6Ra-bind 5,786 2,614 656
PF09291 DUF1968 298 195 72
PF09294 Interfer-bind 9,103 4,557 1,350
PF09394 Inhibitor_I42 5,216 3,258 1,827
PF09459 EB_dh 4,571 3,222 1,067
PF09619 YscW 6,559 2,821 1,167
PF10029 DUF2271 4,580 2,455 488
PF10179 NDNF 1,713 407 138
PF10342 Kre9_KNH 8,675 6,032 3,182
PF10365 DUF2436 145 84 62
PF10420 IL12p40_C 1,250 544 142
PF10430 Ig_Tie2_1 885 207 35
PF10610 Tafi-CsgC 798 166 56
PF10633 NPCBM_assoc 8,213 5,495 2,076
PF10634 Iron_transport 3,197 1,285 216
PF10648 Gmad2 3,262 2,613 1,330
PF11412 DsbD_N 29,835 17,053 4,978
PF11465 Receptor_2B4 781 470 221
PF11545 HemeBinding_Shp 259 136 68
PF11551 Omp28 3,300 2,616 1,666
PF11589 DUF3244 1,325 574 349
PF11606 AlcCBM31 61 53 34
PF11614 FixG_C 15,644 7,751 765
PF11754 Velvet 6,450 3,991 1,871
PF11766 Candida_ALS_N 449 307 222
PF11806 Enterochelin_N 4,301 1,334 439
PF11838 ERAP1_C 39,555 19,195 5,508
PF11896 GlgE_dom_N_S 10,160 4,939 494
PF11940 DUF3458 15,101 6,878 758
PF11974 bMG3 12,725 6,402 2,084
PF12007 DUF3501 3,274 2,201 330
PF12093 bCoV_NS8 334 26 8
PF12245 Big_3_2 4,032 1,462 1,151
PF12262 Lipase_bact_N 1,404 845 257
PF12371 TMEM131_like_N 3,288 1,341 413
PF12505 DUF3712 3,407 2,041 691
PF12567 CD45 580 134 25
PF12580 TPPII 3,225 1,305 462
PF12628 Inhibitor_I71 66 27 14
PF12690 BsuPI 2,144 1,661 938
PF12733 Cadherin-like 6,594 4,660 3,068
PF12744 ATG19 81 56 31
PF12751 Vac7 1,243 665 237
PF12975 DUF3859 1,230 725 286
PF12988 TraQ_transposon 2,440 565 125
PF13004 BACON 7,365 4,204 2,928
PF13205 Big_5 27,300 21,557 13,094
PF13287 Fn3_assoc 8,242 5,218 2,512
PF13290 CHB_HEX_C_1 16,822 12,230 6,852
PF13501 SoxY 7,765 4,680 785
PF13573 SprB 12,755 11,445 8,463
PF13584 BatD 13,121 8,696 4,070
PF13585 CHU_C 44,847 38,663 21,972
PF13629 T2SS-T3SS_pil_N 14,695 8,033 2,068
PF13750 Big_3_3 2,165 1,000 786
PF13752 DUF4165 1,063 152 91
PF13753 SWM_repeat 1,163 998 753
PF13754 Big_3_4 86 53 39
PF13786 DUF4179 5,376 3,168 1,462
PF13860 FlgD_ig 40,269 30,524 19,885
PF13895 Ig_2 44,229 23,388 10,390
PF13927 Ig_3 204,048 91,503 31,333
PF14292 SusE 4,488 2,829 940
PF14310 Fn3-like 71,065 37,108 6,343
PF14467 DUF4426 3,105 1,615 437
PF14524 Wzt_C 11,160 7,979 2,187
PF14545 DBB 2,247 840 258
PF14610 Psg1 1,033 608 242
PF14646 MYCBPAP 1,651 910 430
PF14734 DUF4469 1,336 672 323
PF14874 PapD-like 2,143 1,236 700
PF14888 PBP-Tp47_c 213 74 37
PF14930 Qn_am_d_aII 913 452 98
PF15028 PTCRA 190 125 52
PF15096 G6B 462 187 38
PF15418 DUF4625 1,319 917 315
PF15780 ASH 7,784 5,995 4,024
PF15886 CBM39 1,062 716 326
PF15910 V-set_2 958 319 54
PF16132 DUF4843 1,980 1,226 563
PF16158 N_BRCA1_IG 8,919 5,423 2,543
PF16179 RHD_dimer 13,556 4,445 1,050
PF16184 Cadherin_3 8,955 4,866 2,154
PF16215 DUF4876 1,766 950 324
PF16219 DUF4879 1,126 378 128
PF16258 DUF4912 3,865 2,700 1,267
PF16323 DUF4959 1,415 923 321
PF16343 DUF4973 452 175 33
PF16353 LacZ_4 18,859 9,504 2,040
PF16355 DUF4982 13,985 8,595 1,675
PF16370 MetallophosC 3,402 2,040 577
PF16379 DUF4989 85 26 16
PF16389 DUF4998 1,257 901 433
PF16390 DUF4999 114 29 16
PF16392 DUF5001 729 526 138
PF16400 DUF5008 263 177 55
PF16403 Bact_surface_Ig-like 8,215 5,530 3,895
PF16407 PKD_2 1,900 1,145 554
PF16556 IL17R_fnIII_D1 1,497 585 151
PF16562 HECW_N 2,612 1,391 210
PF16578 IL17R_fnIII_D2 1,243 436 76
PF16583 ZirS_C 1,047 28 13
PF16586 DUF5060 4,398 3,603 1,385
PF16640 Big_3_5 8,140 6,730 4,534
PF16655 PhoD_N 18,439 9,557 1,604
PF16656 Pur_ac_phosph_N 25,484 14,999 6,005
PF16680 Ig_4 1,018 534 122
PF16681 Ig_5 925 555 157
PF16706 Izumo-Ig 476 226 80
PF16709 SCAB-Ig 1,277 491 156
PF16723 DUF5065 361 64 26
PF16758 UL141 135 13 6
PF16794 fn3_4 1,985 976 441
PF16820 PKD_3 867 341 140
PF16893 fn3_2 1,517 850 221
PF16967 TcfC 2,540 862 319
PF16974 NAR2 688 382 121
PF17048 Ceramidse_alk_C 5,747 2,637 531
PF17116 T9SS_plug_1st 3,698 2,649 713
PF17142 DUF5115 258 118 61
PF17425 Arylsulfotran_N 4,964 1,131 431
PF17622 UL16 48 3 2
PF17655 IRK_C 20,028 6,293 1,717
PF17725 YBD 7,779 1,940 362
PF17735 BslA 213 71 36
PF17736 Ig_C17orf99 1,643 621 203
PF17737 Ig_C19orf38 292 166 78
PF17744 DUF5581 391 187 82
PF17751 SKICH 6,901 2,531 595
PF17753 Ig_mannosidase 8,908 4,992 1,469
PF17756 RET_CLD1 1,039 282 33
PF17766 fn3_6 21,437 11,435 2,989
PF17786 Mannosidase_ig 9,474 5,244 1,272
PF17789 MG4 10,784 5,285 1,087
PF17790 MG1 4,511 2,245 430
PF17791 MG3 14,823 7,464 1,984
PF17803 Cadherin_4 9,119 7,598 5,873
PF17808 fn3_PAP 2,081 997 257
PF17812 RET_CLD3 1,034 285 34
PF17813 RET_CLD4 914 280 30
PF17892 Cadherin_5 5,134 4,394 3,443
PF17936 Big_6 10,280 5,828 3,713
PF17957 Big_7 20,686 16,014 10,012
PF17960 TIG_plexin 10,310 4,681 576
PF17961 Big_8 5,929 2,951 1,695
PF17962 bMG6 9,925 4,723 1,451
PF17963 Big_9 32,376 26,900 19,465
PF17964 Big_10 13,415 6,278 588
PF17967 Pullulanase_N2 4,041 2,336 385
PF17970 bMG1 3,226 653 155
PF17971 LIFR_D2 1,503 565 147
PF17972 bMG5 10,433 4,974 1,512
PF17973 bMG10 19,691 11,321 4,199
PF17990 LodA_N 1,436 957 304
PF18000 Top6b_C 772 350 49
PF18001 Il13Ra_Ig 333 142 35
PF18003 DUF3823_C 1,213 717 202
PF18020 TIG_2 8,503 3,862 498
PF18200 Big_11 473 414 315
PF18202 TQ 2,189 970 649
PF18207 LIFR_N 572 135 24
PF18316 S-l_SbsC_C 408 344 222
PF18368 Ig_GlcNase 4,200 2,320 480
PF18370 RGI_lyase 4,650 2,793 679
PF18421 Peptidase_M23_N 2,610 1,030 166
PF18432 ECD 2,498 1,712 82
PF18435 EstA_Ig_like 1,337 784 267
PF18447 FN3_7 662 207 26
PF18452 Ig_6 3,967 1,108 255
PF18518 TcA_RBD 156 102 30
PF18565 Glyco_hydro2_C5 13,284 7,872 1,567
PF18589 ObR_Ig 1,498 522 95
PF18611 IL3Ra_N 760 366 145
PF18630 Peptidase_M60_C 281 111 57
PF18649 EcpB_C 483 119 26
PF18673 IrmA 352 101 38
PF18674 TarS_C1 393 198 78
PF18683 ChiW_Ig_like 35 34 28
PF18703 MALT1_Ig 1,901 718 92
PF18705 DUF5643 2,436 1,439 653
PF18707 IL2RB_N1 857 398 97
PF18861 PTP_tm 4,173 1,803 522
PF18911 PKD_4 67,542 51,617 32,381
PF18938 aRib 1,028 823 561
PF18957 RibLong 1,283 921 629
PF18962 Por_Secre_tail 182,800 159,387 102,282
PF18981 InlK_D3 870 223 110
PF19010 DUF5739 36 31 20
PF19019 Phlebo_G2_C 1,132 247 160
PF19076 CshA_repeat 1,614 1,237 774
PF19077 Big_13 15,186 8,727 6,176
PF19078 Big_12 3,402 2,816 2,129
PF19081 Ig_7 8,305 7,474 4,939
PF19092 DUF5780 146 101 78
PF19190 BACON_2 5,703 4,317 3,116
PF19406 PKD_5 1,283 1,199 869
PF19408 PKD_6 3,916 3,531 2,682
PF19433 NDNF_C 1,758 441 154
PF19543 GH123_N 2,613 1,920 1,054
PF19743 ASTN1_2_fn3 2,502 599 83
PF19910 DUF6383 1,461 740 486
PF20144 TIG_SUH 3,877 1,280 336
PF20164 GspA_SrpA_N 142 115 70
PF20238 BIM1-like_dom 4,157 2,387 745
PF20251 Big_14 1,694 1,077 742
PF20264 DUF4784_N 130 30 18
PF20578 aBig_2 4,109 2,691 1,433
PF20579 LapA 1,858 1,363 815
PF20622 Big_15 1,972 820 440
PF20676 Herpes_gp350_B 241 9 4
PF20677 Herpes_gp350_C 239 7 2
PF20679 Hanta_Gn-B 946 110 28
PF20682 Hanta_Gc_C 2,154 211 59
PF20775 Tag1 636 292 88
PF20805 Integrin_A_Ig_2 19,582 7,113 1,468
PF20806 Integrin_A_Ig_3 14,684 5,169 1,108
PF20942 DUF4785_2nd 85 62 31
PF20943 DUF4785_3rd 523 331 179
PF20989 Sarcoglycan_2_C 3,371 907 185
PF21027 Sde0182_C 3,207 2,067 480
PF21060 Reovirus_L2_6th 81 8 4
PF21061 Reovirus_L2_7th 134 30 14
PF21112 CsgH 453 321 175
PF21142 A2M_bMG2 6,365 2,309 521
PF21145 C4_MG1 419 168 23
PF21146 ICAM1_3_5_D2 1,059 461 148
PF21160 PrkC-like_PASTA-like 1,030 424 51
PF21171 PDE12-like_N 1,043 459 151
PF21172 CueP 1,800 774 197
PF21177 LIF-R_Ig-like 1,325 449 119
PF21200 Glyco_hydro_39_C 1,079 342 89
PF21223 TPPII_Ig-like-1 3,154 1,261 415
PF21226 MalQ_N 4,491 1,502 226
PF21310 OCRL-like_ASH 5,298 2,286 565
PF21339 VEGFR-1-like_Ig-like 5,402 1,717 278
PF21426 GBS104-like_Ig 568 215 128
PF21460 IL3Rb_N 789 399 107
PF21461 HL_N-beta 435 160 103
PF21520 ITGAX-like_Ig_3 1,914 822 209
PF21577 PG_0320-like_C 23 10 7
PF21601 GldM_2nd 3,790 2,503 544
PF21602 GldM_3rd 3,967 2,614 627
PF21604 CRLF2_D1 1,425 601 157
PF21605 CRLF2-like_D2 1,534 672 156
PF21633 MOV-10_Ig-like 1,647 642 102
PF21764 Invasin_D4 456 246 144
CL0161 GAF 649,463 357,335 117,280 PF00360 PHY 19,687 7,360 1,605
PF01590 GAF 224,877 130,067 50,380
PF01614 IclR 122,763 56,523 12,788
PF01628 HrcA 29,797 13,946 2,465
PF03472 Autoind_bind 16,898 7,894 2,599
PF03928 HbpS-like 32,684 16,608 2,940
PF04340 DUF484 11,127 5,219 1,186
PF06018 CodY 4,462 1,397 120
PF07701 HNOBA 12,451 5,867 2,238
PF09884 DUF2111 502 279 39
PF11152 CCB2_CCB4 1,897 995 298
PF11849 DUF3369 4,019 2,238 599
PF12282 PdtaS_GAF 6,666 2,280 348
PF13185 GAF_2 164,927 111,099 48,325
PF13492 GAF_3 19,501 11,626 5,603
PF14215 bHLH-MYC_N 9,170 4,004 1,131
PF15714 SpoVT_C 4,428 2,012 243
PF18007 Rv3651-like_N 898 443 119
PF18092 DraK_HK_N 1,686 564 48
CL0163 Calcineurin 613,094 332,384 90,290 PF00149 Metallophos 460,060 244,412 68,793
PF04042 DNA_pol_E_B 14,595 7,356 2,233
PF06874 FBPase_2 4,903 1,920 260
PF09423 PhoD 30,795 17,629 4,043
PF09587 PGA_cap 26,553 17,291 6,538
PF12850 Metallophos_2 55,703 32,727 7,551
PF13258 DUF4049 489 58 30
PF13277 YmdB 14,931 8,581 1,011
PF14582 Metallophos_3 447 317 206
PF19050 PhoD_2 4,517 2,342 479
PF21663 WipA_Phos 175 130 96
CL0164 CUB 82,792 36,404 14,107 PF00431 CUB 75,789 33,814 13,386
PF02408 CUB_2 587 432 241
PF21308 C3_CUB2 2,202 1,161 190
PF21309 C5_CUB 962 385 66
PF21406 C3_CUB1 761 449 107
PF21412 TEP1_CUB2 501 182 92
PF21765 A2MG_CUB 2,608 316 58
CL0165 Cache 249,181 126,246 47,100 PF02743 dCache_1 78,571 42,828 17,804
PF03924 CHASE 17,620 11,049 5,159
PF05228 CHASE4 6,948 4,514 2,351
PF05651 Diacid_rec 6,591 2,302 859
PF08269 dCache_2 6,875 4,798 2,332
PF08473 VGCC_alpha2 7,621 3,385 608
PF08521 2CSK_N 18,730 8,211 1,554
PF08918 PhoQ_Sensor 1,460 210 37
PF09308 LuxQ-periplasm 425 202 76
PF09984 sCache_4 5,641 1,603 482
PF10114 PocR 7,470 4,821 2,611
PF10144 SMP_2 3,078 750 170
PF10388 YkuI_C 1,879 632 128
PF13756 Stimulus_sens_1 3,154 1,464 207
PF14827 dCache_3 7,221 5,115 2,492
PF16524 RisS_PPD 1,869 810 82
PF16736 sCache_like 4,657 2,775 1,070
PF16750 HK_sensor 1,492 512 59
PF17149 CHASE5 2,000 1,170 535
PF17151 CHASE7 1,354 236 73
PF17152 CHASE8 6,587 3,583 1,761
PF17154 GAPES3 1,698 238 35
PF17155 GAPES1 1,477 125 46
PF17157 GAPES4 1,948 325 39
PF17200 sCache_2 18,591 8,889 2,699
PF17201 Cache_3-Cache_2 5,851 3,086 1,316
PF17202 sCache_3_3 4,900 3,319 1,247
PF17203 sCache_3_2 19,936 8,288 1,863
PF18698 HisK_sensor 1,501 565 37
PF18719 ArlS_N 2,572 1,030 218
CL0166 PRD 36,141 13,465 4,921 PF00874 PRD 35,402 13,300 4,821
PF08270 PRD_Mga 737 165 100
CL0167 Zn_Beta_Ribbon 1,435,659 665,039 177,512 PF00105 zf-C4 83,300 27,706 9,737
PF00320 GATA 41,525 19,973 7,810
PF00412 LIM 116,960 46,392 12,083
PF00471 Ribosomal_L33 57,062 11,622 734
PF00641 zf-RanBP 28,370 11,685 4,185
PF00645 zf-PARP 6,505 3,370 1,231
PF00935 Ribosomal_L44 8,084 3,129 597
PF01020 Ribosomal_L40e 5,288 2,032 608
PF01096 TFIIS_C 20,464 8,799 2,214
PF01258 zf-dskA_traR 56,028 28,330 5,869
PF01396 zf-C4_Topoisom 43,053 20,006 3,683
PF01599 Ribosomal_S27 7,275 2,906 643
PF01667 Ribosomal_S27e 9,918 3,705 784
PF01741 MscL 32,418 17,114 1,721
PF01780 Ribosomal_L37ae 8,144 3,429 856
PF01783 Ribosomal_L32p 54,690 16,550 1,737
PF01807 zf-CHC2 57,861 30,094 8,620
PF01907 Ribosomal_L37e 7,196 2,687 497
PF02150 RNA_POL_M_15KD 8,909 3,698 912
PF02565 RecO_C 41,267 21,814 5,725
PF02591 zf-RING_7 14,579 8,449 2,240
PF03367 zf-ZPR1 6,082 3,263 882
PF03604 DNA_RNApol_7kD 4,316 1,783 562
PF03811 Zn_Tnp_IS1 3,845 1,574 671
PF03966 Trm112p 27,392 14,022 2,277
PF04606 Ogr_Delta 4,921 1,568 491
PF05129 Elf1 4,473 2,167 648
PF05207 zf-CSL 6,379 3,260 985
PF05265 DUF723 154 102 92
PF05810 NinF 811 113 39
PF06093 Spt4 6,658 2,952 592
PF06677 Auto_anti-p27 3,441 2,169 902
PF06689 zf-C4_ClpX 40,972 12,863 1,058
PF06827 zf-FPG_IleRS 61,500 29,481 3,369
PF06839 zf-GRF 16,088 8,677 3,604
PF07191 zinc-ribbons_6 1,737 566 109
PF07282 OrfB_Zn_ribbon 55,604 28,579 8,697
PF07295 DUF1451 3,594 1,472 366
PF07754 HVO_2753_ZBP 2,529 1,281 128
PF08063 PADR1_Zn_ribbon 2,726 1,163 387
PF08271 TF_Zn_Ribbon 15,904 6,344 1,657
PF08272 Topo_Zn_Ribbon 5,430 1,045 60
PF08273 Prim_Zn_Ribbon 4,276 1,515 592
PF08274 YjdM_Zn_Ribbon 11,139 3,921 115
PF08772 NOB1_Zn_bind 3,816 2,035 496
PF08792 A2L_zn_ribbon 392 191 125
PF09151 DUF1936 12 10 6
PF09297 zf-NADH-PPase 19,968 9,155 1,517
PF09526 DUF2387 4,216 1,157 195
PF09723 Zn-ribbon_8 32,400 22,148 4,829
PF09845 DUF2072 1,438 980 223
PF09855 zinc_ribbon_13 2,261 1,245 260
PF09889 DUF2116 1,399 918 405
PF09947 DUF2180 719 404 132
PF10005 zinc-ribbon_6 5,056 2,421 265
PF10058 zinc_ribbon_10 4,214 2,081 700
PF10122 Mu-like_Com 1,145 671 307
PF10571 UPF0547 1,649 862 445
PF11023 DUF2614 1,507 632 79
PF11331 zinc_ribbon_12 1,971 847 339
PF11682 zinc_ribbon_11 1,008 274 93
PF11781 zf-RRN7 2,017 1,076 400
PF11792 Baculo_LEF5_C 177 84 20
PF12172 DUF35_N 27,766 17,063 3,557
PF12677 DUF3797 362 92 41
PF12760 Zn_Tnp_IS1595 7,959 5,459 1,880
PF12773 DZR 21,105 15,070 7,374
PF12898 Stc1 1,069 675 363
PF13101 DUF3945 3,197 794 250
PF13240 zinc_ribbon_2 33,020 23,192 15,060
PF13248 zf-ribbon_3 4,150 2,983 2,101
PF13342 Toprim_Crpt 10,196 3,824 796
PF13408 Zn_ribbon_recom 38,064 21,174 9,003
PF13451 zf-trcl 5,795 3,547 801
PF13453 zf-TFIIB 10,977 7,348 2,496
PF13717 zinc_ribbon_4 7,230 5,797 3,008
PF13719 zinc_ribbon_5 3,680 2,335 922
PF13842 Tnp_zf-ribbon_2 1,207 732 543
PF14311 DUF4379 2,442 1,774 1,124
PF14353 CpXC 1,923 1,393 745
PF14354 Lar_restr_allev 1,937 1,343 985
PF14369 zinc_ribbon_9 5,202 2,495 782
PF14690 zf-ISL3 13,208 6,819 3,114
PF14803 Nudix_N_2 8,898 4,404 604
PF17032 zinc_ribbon_15 3,289 1,975 680
PF17283 Zn_ribbon_SprT 6,153 2,358 473
PF17848 zf-ACC 21,920 9,215 518
PF17915 zf_Rg 816 565 241
PF18073 Rubredoxin_2 45,707 18,008 1,890
PF18319 PriA_CRR 34,111 17,388 3,199
PF18445 zf_PR_Knuckle 721 136 26
PF18912 DZR_2 14,461 9,986 3,327
PF20214 DUF6574 789 239 155
PF20864 TEX13_ZnF 314 178 90
PF21302 RlmA_N 9,757 4,158 840
PF21319 zf-FCS_1 6,662 1,578 315
PF21326 KDM6_GATAL 4,648 1,589 291
PF21344 LysW-like_globular 3,141 1,808 372
PF21352 Thio2_N 7,435 3,438 307
PF21372 TOP1_ZnF 5,428 1,059 57
PF21817 CapR 568 303 236
CL0168 PAN 61,898 34,535 16,662 PF00024 PAN_1 24,834 14,954 8,569
PF02430 AMA-1 4,045 392 89
PF07502 MANEC 3,564 1,685 469
PF08276 PAN_2 21,841 12,730 4,690
PF08277 PAN_3 1,092 793 540
PF14295 PAN_4 8,857 5,418 3,387
CL0169 Rep 90,213 34,518 13,906 PF00799 Gemini_AL1 11,458 2,181 524
PF01076 Mob_Pre 6,997 2,784 1,425
PF01446 Rep_1 2,473 1,341 728
PF01719 Rep_2 1,440 723 310
PF02217 T_Ag_DNA_bind 856 186 46
PF02407 Viral_Rep 7,131 2,210 1,241
PF03389 MobA_MobL 11,787 4,807 1,910
PF03432 Relaxase 26,016 10,803 4,039
PF05840 Phage_GPA 5,068 1,691 655
PF07232 DUF1424 116 84 43
PF08724 Rep_N 937 103 48
PF08751 TrwC 8,922 5,605 2,224
PF12433 PV_NSP1 1,371 175 22
PF18555 MobL 1,913 957 497
PF20450 PPV_E1_DBD 3,714 869 196
CL0170 Peptidase_MD 77,628 44,010 13,524 PF01085 HH_signal 4,047 1,360 414
PF01427 Peptidase_M15 15,697 8,788 1,768
PF02557 VanY 21,875 13,533 4,999
PF03411 Peptidase_M74 6,542 3,442 914
PF05951 Peptidase_M15_2 8,091 4,267 1,004
PF08291 Peptidase_M15_3 9,102 5,367 1,981
PF13539 Peptidase_M15_4 12,284 7,284 2,521
CL0171 Phospoesterase 163,890 79,598 14,187 PF00316 FBPase 26,103 10,129 1,295
PF00459 Inositol_P 118,047 62,636 12,278
PF03320 FBPase_glpX 19,737 6,833 614
CL0172 Thioredoxin 1,671,729 882,430 203,774 PF00085 Thioredoxin 233,351 115,353 30,286
PF00255 GSHPx 47,083 22,851 3,081
PF00462 Glutaredoxin 108,550 52,528 10,802
PF00578 AhpC-TSA 237,222 136,937 36,305
PF00837 T4_deiodinase 4,348 1,928 663
PF01216 Calsequestrin 2,881 1,201 146
PF01257 2Fe-2S_thioredx 63,782 36,517 5,307
PF01323 DSBA 73,833 39,679 8,757
PF02114 Phosducin 10,339 3,308 809
PF02630 SCO1-SenC 47,750 29,568 8,180
PF02798 GST_N 106,535 52,436 10,289
PF02966 DIM1 5,556 1,586 458
PF03190 Thioredox_DsbH 26,386 17,541 4,087
PF03227 GILT 7,099 4,465 1,910
PF03960 ArsC 52,132 25,539 2,420
PF04592 SelP_N 1,683 951 400
PF04756 OST3_OST6 7,419 2,844 862
PF04908 SH3BGR 6,078 2,699 921
PF05047 L51_S25_CI-B8 8,802 3,931 891
PF05176 ATP-synt_10 2,485 1,500 544
PF05768 Glrx-like 16,811 9,465 2,216
PF05988 DUF899 11,789 6,232 694
PF06053 DUF929 578 383 211
PF06110 TXD17-like_Trx 3,371 1,723 638
PF06764 DUF1223 6,992 4,582 1,522
PF06953 ArsD 3,547 1,718 405
PF07315 DUF1462 1,365 588 59
PF07449 HyaE 1,988 601 178
PF07511 DUF1525 1,898 728 254
PF07689 KaiB 4,848 2,832 579
PF07912 ERp29_N 1,138 442 167
PF07955 DUF1687 1,364 771 198
PF07976 Phe_hydrox_dim 7,501 3,846 559
PF08534 Redoxin 94,434 50,860 13,893
PF08806 Sep15_SelM 2,412 1,242 426
PF09695 YtfJ_HI0045 2,720 845 217
PF10262 Rdx 13,883 7,351 1,806
PF10484 MRP-S23 1,400 698 276
PF10568 Tom37 5,541 2,490 825
PF10865 DUF2703 896 710 276
PF11009 BrxC 4,564 3,006 620
PF13098 Thioredoxin_2 30,997 16,178 5,323
PF13192 Thioredoxin_3 26,244 13,827 2,458
PF13409 GST_N_2 112,105 55,256 9,481
PF13417 GST_N_3 65,543 35,611 8,597
PF13462 Thioredoxin_4 52,822 32,758 11,639
PF13728 TraF 5,144 1,836 758
PF13741 MRP-S25 1,502 865 205
PF13743 Thioredoxin_5 4,721 2,540 661
PF13778 DUF4174 6,605 3,127 965
PF13848 Thioredoxin_6 19,301 8,151 2,270
PF13899 Thioredoxin_7 39,334 23,326 7,198
PF13905 Thioredoxin_8 26,767 16,273 7,839
PF13911 AhpC-TSA_2 9,457 5,520 1,849
PF14595 Thioredoxin_9 6,456 4,293 1,134
PF17172 GST_N_4 6,584 3,511 1,131
PF18078 Thioredoxin_11 2,823 1,468 531
PF18108 QSOX_Trx1 2,102 806 184
PF18400 Thioredoxin_12 5,385 2,606 572
PF18401 Thioredoxin_13 5,373 2,610 572
PF18402 Thioredoxin_14 5,523 2,708 637
PF18403 Thioredoxin_15 5,423 2,456 454
PF18485 GST_N_5 1,120 376 72
PF18569 Thioredoxin_16 1,492 493 180
PF20029 DUF6436 1,408 542 149
PF20207 DUF6568 303 145 97
PF21021 FAF1 4,994 1,769 674
PF21274 Rng_hyd_C 21,561 13,584 1,986
CL0173 STIR 107,669 66,168 32,273 PF01582 TIR 44,447 23,648 9,514
PF08357 SEFIR 7,311 3,334 1,278
PF08937 ThsB_TIR 5,309 3,915 1,014
PF10137 CAP12-PCTIR_TIR 3,565 2,725 1,379
PF13676 TIR_2 45,539 32,190 19,404
PF18567 TIR_3 1,554 550 124
CL0174 TetR_C 438,531 229,803 51,927 PF02909 TetR_C_1 34,296 20,131 3,390
PF08359 TetR_C_4 5,383 3,374 1,078
PF08360 TetR_C_5 1,158 531 212
PF08361 TetR_C_2 6,980 2,196 544
PF08362 TetR_C_3 9,583 2,896 348
PF08511 COQ9 6,749 4,000 989
PF09209 CecR_C 5,212 2,648 971
PF13305 TetR_C_33 39,037 22,676 4,746
PF13972 TetR 6,675 2,371 592
PF13977 TetR_C_6 38,495 20,765 5,411
PF14246 TetR_C_7 25,428 13,038 3,645
PF14278 TetR_C_8 18,720 9,102 3,475
PF14514 TetR_C_9 596 298 113
PF16295 TetR_C_10 2,264 1,310 394
PF16859 TetR_C_11 30,710 17,173 3,512
PF16914 TetR_C_12 449 189 31
PF16925 TetR_C_13 18,527 9,971 2,330
PF17754 TetR_C_14 15,909 9,518 1,873
PF17918 TetR_C_15 5,469 3,268 1,052
PF17920 TetR_C_16 9,674 5,812 1,149
PF17922 TetR_C_17 756 514 214
PF17923 TetR_C_18 1,053 497 30
PF17924 TetR_C_19 977 491 191
PF17925 TetR_C_20 3,660 1,392 249
PF17926 TetR_C_21 3,581 2,177 429
PF17928 TetR_C_22 4,740 1,863 371
PF17929 TetR_C_34 2,874 1,779 497
PF17931 TetR_C_23 3,578 2,011 345
PF17932 TetR_C_24 39,834 20,595 4,982
PF17933 TetR_C_25 1,560 1,004 217
PF17934 TetR_C_26 666 220 63
PF17935 TetR_C_27 5,509 2,423 428
PF17937 TetR_C_28 7,134 3,461 966
PF17938 TetR_C_29 10,352 4,608 1,244
PF17939 TetR_C_30 8,626 4,008 1,076
PF17940 TetR_C_31 13,079 6,645 1,390
PF18285 LuxT_C 563 217 52
PF18556 TetR_C_35 2,791 1,383 289
PF18598 TetR_C_36 927 551 147
PF18665 TetR_C_37 312 221 52
PF19344 TetR_C_32 7,426 2,332 313
PF19352 TetR_C_38 1,385 337 87
PF21256 TetR_C_5-like 606 405 175
PF21303 TetR_C_39 1,893 994 305
PF21306 TetR_C_40 2,349 1,339 336
PF21313 EthR_C 3,036 1,564 349
PF21351 TetR_C_41 6,569 3,167 540
PF21542 TetR_C_42 14 14 9
PF21597 TetR_C_43 21,007 12,482 1,787
PF21626 TetR-C_39 127 46 21
PF21776 TetR_C_44 216 120 41
CL0175 TRASH 154,913 85,451 30,066 PF01246 Ribosomal_L24e 11,621 4,759 994
PF01753 zf-MYND 56,999 33,053 17,217
PF03884 YacG 12,805 7,139 1,249
PF04438 zf-HIT 12,745 6,572 2,362
PF04570 zf-FLZ 6,793 3,420 1,216
PF04945 YHS 18,505 11,166 2,922
PF05573 NosL 7,299 5,053 1,408
PF06467 zf-FCS 6,263 2,017 567
PF08394 Arc_trans_TRASH 701 480 255
PF10013 DUF2256 6,574 4,529 566
PF12156 ATPase-cat_bd 9,232 4,997 988
PF13824 zf-Mss51 1,494 757 110
PF15801 zf-C6H2 3,875 1,517 273
CL0176 Chemosens_recp 36,776 27,201 15,572 PF02949 7tm_6 25,012 17,990 9,609
PF03268 DUF267 236 175 109
PF06151 Trehalose_recp 1,857 1,366 881
PF08395 7tm_7 9,679 7,691 5,020
CL0177 PBP 2,622,684 1,206,971 258,494 PF00405 Transferrin 6,040 2,616 915
PF00496 SBP_bac_5 276,589 135,086 33,566
PF00497 SBP_bac_3 277,133 120,199 32,233
PF00800 PDT 45,192 22,108 3,628
PF01379 Porphobil_deam 42,948 21,015 3,163
PF01547 SBP_bac_1 174,137 90,204 23,141
PF01634 HisG 40,414 16,864 1,484
PF02030 Lipoprotein_8 179 129 73
PF02621 VitK2_biosynth 16,922 9,728 2,010
PF03180 Lipoprotein_9 35,856 11,250 1,358
PF03401 TctC 128,183 74,858 18,745
PF03466 LysR_substrate 812,876 319,310 59,776
PF03480 DctP 95,289 53,360 10,640
PF04069 OpuAC 60,956 24,654 3,543
PF06646 CypI 176 104 61
PF09084 NMT1 100,942 52,261 12,389
PF10613 Lig_chan-Glu_bd 43,880 17,300 5,504
PF12727 PBP_like 10,162 6,221 1,078
PF12849 PBP_like_2 73,588 40,670 7,782
PF12916 DUF3834 114 80 40
PF12974 Phosphonate-bd 39,177 22,702 6,599
PF13343 SBP_bac_6 46,088 21,797 4,207
PF13379 NMT1_2 37,679 18,362 3,802
PF13416 SBP_bac_8 177,816 83,197 20,364
PF13531 SBP_bac_11 69,627 36,027 7,890
PF14503 YhfZ_C 1,111 459 159
PF16868 NMT1_3 31,844 18,979 4,452
CL0178 PUA 308,920 149,758 29,047 PF01472 PUA 49,689 22,313 3,166
PF01878 EVE 21,887 12,216 1,849
PF02182 SAD_SRA 9,702 5,169 2,001
PF02190 LON_substr_bdg 79,382 36,749 6,475
PF03657 UPF0113 4,197 1,602 420
PF04033 DUF365 130 95 29
PF04146 YTH 15,480 5,937 1,971
PF04266 ASCH 19,058 10,114 3,031
PF08819 DUF1802 2,514 1,690 395
PF09142 TruB_C 5,221 2,581 243
PF09157 TruB-C_2 11,126 4,804 754
PF09627 PrgU 46 9 6
PF10763 DUF2584 841 307 41
PF12961 DUF3850 2,059 1,209 530
PF13636 Methyltranf_PUA 9,562 4,348 987
PF14306 PUA_2 16,989 7,945 884
PF17785 PUA_3 21,910 10,759 1,510
PF18062 RE_AspBHI_N 482 367 123
PF18491 SRA 308 217 127
PF20260 PUA_4 38,326 21,343 4,559
CL0179 ATP-grasp 854,962 413,798 75,646 PF01068 DNA_ligase_A_M 63,399 35,154 7,087
PF01071 GARS_A 51,630 25,155 2,692
PF01326 PPDK_N 67,596 37,729 7,490
PF01331 mRNA_cap_enzyme 5,608 2,739 972
PF01653 DNA_ligase_aden 53,863 27,814 3,885
PF02222 ATP-grasp 46,352 19,883 2,000
PF02655 ATP-grasp_3 10,678 7,629 3,486
PF02750 Synapsin_C 4,332 1,615 452
PF02786 CPSase_L_D2 202,607 83,568 8,599
PF02955 GSH-S_ATP 19,195 8,338 1,097
PF03133 TTL 27,121 13,862 5,766
PF03738 GSP_synth 12,939 3,946 711
PF04174 CP_ATPgrasp_1 1,030 495 198
PF05770 Ins134_P3_kin 4,603 2,049 679
PF06973 DUF1297 3,547 1,760 166
PF07065 D123 4,620 2,349 909
PF07478 Dala_Dala_lig_C 67,828 35,804 6,165
PF08442 ATP-grasp_2 49,570 17,433 1,967
PF08443 RimK 37,718 19,319 4,028
PF09414 RNA_ligase 7,790 4,386 1,359
PF09511 RNA_lig_T4_1 3,930 1,959 706
PF13535 ATP-grasp_4 17,824 10,611 3,491
PF13549 ATP-grasp_5 36,430 21,254 4,641
PF14243 R2K_3 1,630 1,145 435
PF14305 ATPgrasp_TupA 4,303 3,025 1,470
PF14397 ATPgrasp_ST 6,680 3,926 1,569
PF14398 ATPgrasp_YheCD 8,575 5,029 1,832
PF14403 CP_ATPgrasp_2 21,095 8,991 1,031
PF15632 ATPgrasp_Ter 7,181 4,861 1,810
PF16542 PNKP_ligase 3,259 1,864 185
PF18299 R2K_2 1,286 865 329
PF18419 ATP-grasp_6 1,726 590 88
PF19043 CBP66 39 22 8
PF21004 MCEL_GT_NTPase 184 37 3
PF21798 DUF6878 735 296 131
CL0181 ABC-2 520,623 276,204 69,604 PF01061 ABC2_membrane 197,946 103,186 21,960
PF02588 YitT_membrane 37,948 16,897 2,891
PF03379 CcmB 19,230 8,605 1,517
PF06182 ABC2_membrane_6 20,768 11,506 3,017
PF06422 PDR_CDR 13,625 6,329 983
PF09847 12TM_1 355 247 165
PF10920 DUF2705 158 66 52
PF12040 DUF3526 3,340 2,207 618
PF12051 DUF3533 4,513 2,461 887
PF12679 ABC2_membrane_2 58,974 37,410 11,598
PF12698 ABC2_membrane_3 136,624 73,049 20,450
PF12730 ABC2_membrane_4 22,636 11,907 4,054
PF13346 ABC2_membrane_5 8,268 4,314 2,366
PF16949 ABC_tran_2 3,349 2,373 1,146
PF16962 ABC_export 1,056 734 417
PF19055 ABC2_membrane_7 47,044 22,358 5,434
PF19700 DUF6198 3,162 1,747 583
CL0182 IT 417,983 193,924 35,484 PF00939 Na_sulph_symp 36,747 16,888 4,629
PF02040 ArsB 8,254 2,790 484
PF02447 GntP_permease 31,762 10,508 1,538
PF02652 Lactate_perm 19,183 6,861 1,285
PF02667 SCFA_trans 7,914 3,070 540
PF03124 EXS 10,588 5,082 1,741
PF03553 Na_H_antiporter 36,493 15,657 2,513
PF03600 CitMHS 74,564 37,587 7,605
PF03605 DcuA_DcuB 8,315 1,714 271
PF03606 DcuC 17,152 6,361 1,332
PF03773 ArsP_1 29,104 17,389 2,936
PF03806 ABG_transport 9,021 4,200 674
PF04165 DUF401 1,884 1,454 704
PF04346 EutH 2,736 950 209
PF06450 NhaB 3,969 1,122 99
PF06808 DctM 107,165 55,510 8,346
PF07158 MatC_N 3,331 1,407 242
PF07399 Na_H_antiport_3 1,810 1,178 159
PF07854 DUF1646 812 477 96
PF11449 ArsP_2 2,853 1,731 439
PF13726 Na_H_antiport_2 5,661 1,399 85
PF16980 CitMHS_2 5,310 2,895 379
CL0183 PAS_Fold 866,474 522,382 219,990 PF00989 PAS 228,577 134,855 66,255
PF07310 PAS_5 4,948 3,563 1,901
PF08348 PAS_6 9,242 3,172 786
PF08446 PAS_2 12,124 6,214 1,453
PF08447 PAS_3 208,585 130,005 64,005
PF08448 PAS_4 225,748 150,209 77,454
PF08670 MEKHLA 4,815 2,185 427
PF12860 PAS_7 31,079 16,405 5,847
PF13188 PAS_8 72,655 47,895 27,194
PF13426 PAS_9 260,116 175,720 92,885
PF13596 PAS_10 14,939 9,520 3,078
PF14598 PAS_11 21,804 8,077 1,824
PF16527 CpxA_peri 1,698 266 31
PF17765 MLTR_LBD 38,864 22,612 3,108
PF18095 PAS_12 63 46 29
PF18225 AbfS_sensor 116 95 33
PF18621 Rv3651-like_middle 489 190 14
PF21043 Rv3651-like_C 689 313 56
PF21085 CusS 4,377 1,313 254
PF21353 Per3-like_PAS-A 3,637 1,735 174
PF21370 GdpP_PAS 3,788 1,257 179
PF21563 Mcp40H-20_sensor 537 403 205
PF21815 PdeA_PAS 197 65 18
CL0184 DMT 757,050 380,101 89,945 PF00892 EamA 429,197 222,934 53,702
PF00893 Multi_Drug_Res 48,753 20,278 2,087
PF02535 Zip 69,550 35,277 8,286
PF02537 CRCB 47,009 26,590 6,440
PF02694 UPF0060 11,940 5,108 370
PF03151 TPT 36,879 16,255 4,564
PF04142 Nuc_sug_transp 16,510 7,601 2,668
PF04342 DMT_6 7,511 3,876 223
PF04657 DMT_YdcZ 19,027 8,675 1,967
PF05653 Mg_trans_NIPA 20,976 9,367 2,668
PF06027 SLC35F 7,378 3,547 1,219
PF06379 RhaT 3,898 1,742 295
PF06800 Sugar_transport 3,331 1,068 281
PF07168 Ureide_permease 2,363 1,274 246
PF07857 TMEM144 2,693 1,447 699
PF08449 UAA 14,660 6,938 2,317
PF08627 CRT-like 2,402 1,309 648
PF10639 TMEM234 3,076 1,621 511
PF13536 EmrE 2,230 945 125
PF16913 PUNUT 5,329 2,744 873
PF16965 CSG2 352 165 42
PF19451 DUF5989 2,301 1,812 375
CL0186 Beta_propeller 2,654,685 1,364,501 510,309 PF00058 Ldl_recept_b 27,642 11,336 3,351
PF00064 Neur 101,453 727 133
PF00400 WD40 726,943 342,622 123,556
PF00415 RCC1 65,306 36,443 16,481
PF00423 HN 7,779 367 152
PF00780 CNH 36,321 17,350 2,973
PF00930 DPPIV_N 42,569 22,599 5,111
PF01011 PQQ 24,348 12,823 5,028
PF01344 Kelch_1 121,300 48,029 19,490
PF01394 Clathrin_propel 6,543 1,766 275
PF01403 Sema 44,755 16,250 2,414
PF01436 NHL 74,430 41,661 18,581
PF01453 B_lectin 30,485 17,724 6,137
PF01731 Arylesterase 2,854 1,538 579
PF01839 FG-GAP 39,769 22,342 11,278
PF02012 BNR 7,008 5,099 2,788
PF02191 OLF 19,402 7,157 1,016
PF02239 Cytochrom_D1 34,155 10,520 1,300
PF02333 Phytase 5,324 3,104 759
PF02897 Peptidase_S9_N 43,420 23,172 4,580
PF03022 MRJP 8,949 5,172 1,546
PF03055 RPE65 27,507 14,286 4,072
PF03088 Str_synth 10,487 5,128 1,463
PF03089 RAG2 14,296 1,189 82
PF03178 CPSF_A 14,506 5,850 1,881
PF03451 HELP 10,635 3,591 825
PF03478 DUF295 23,446 14,972 7,828
PF03984 DUF346 856 591 284
PF04053 Coatomer_WDAD 11,484 4,657 990
PF04762 IKI3 4,730 2,453 845
PF04841 Vps16_N 4,445 1,948 732
PF05096 Glu_cyclase_2 8,086 5,589 1,593
PF05131 Pep3_Vps18 4,247 1,678 607
PF05220 MgpC 241 38 7
PF05567 Neisseria_PilC 6,966 5,229 2,318
PF05694 SBP56 6,591 2,899 571
PF05787 PhoX 23,082 11,097 1,631
PF05935 Arylsulfotrans 10,473 5,054 2,275
PF06433 Me-amine-dh_H 1,300 678 214
PF06462 Hyd_WA 2,842 1,242 349
PF06739 SBBP 8,444 7,146 5,625
PF06977 SdiA-regulated 6,512 2,645 1,116
PF07250 Glyoxal_oxid_N 6,502 3,850 809
PF07433 DUF1513 4,263 1,964 479
PF07494 Reg_prop 46,014 31,339 17,016
PF07569 Hira 4,342 1,937 530
PF07646 Kelch_2 8,578 3,398 1,394
PF07676 PD40 139,529 98,049 40,086
PF07734 FBA_1 12,169 7,611 4,082
PF07893 DUF1668 3,317 2,121 1,281
PF07938 Fungal_lectin 965 669 441
PF07995 GSDH 68,659 42,711 9,658
PF08149 BING4CT 3,572 1,740 436
PF08168 NUC205 1,321 495 152
PF08268 FBA_3 9,869 6,349 3,557
PF08309 LVIVD 18,040 13,430 6,945
PF08310 LGFP 6,484 3,959 1,678
PF08450 SGL 62,154 36,078 8,865
PF08553 VID27 2,646 1,251 349
PF08596 Lgl_C 5,328 1,972 425
PF08662 eIF2A 12,440 4,841 1,679
PF08801 Nucleoporin_N 7,133 3,437 1,104
PF08953 DUF1899 11,950 4,298 806
PF09826 Beta_propel 5,738 4,420 2,307
PF10168 Nup88 2,733 1,259 547
PF10214 Rrn6_beta-prop 1,196 751 414
PF10282 Lactonase 38,740 22,280 7,831
PF10313 DUF2415 1,787 998 380
PF10433 MMS1_N 13,824 5,944 1,873
PF10647 Gmad1 5,211 3,017 1,022
PF11635 Med16_N 2,498 933 288
PF11715 Nup160 4,707 2,340 877
PF11768 Frtz 1,593 714 215
PF11949 DUF3466 1,382 957 428
PF12195 End_beta_barrel 66 16 6
PF12217 End_beta_propel 97 24 13
PF12256 TcdB_toxin_midN 3,522 2,822 1,685
PF12265 CAF1C_H4-bd 11,117 4,370 974
PF12275 DUF3616 2,217 1,508 530
PF12341 Mcl1_mid 3,998 2,102 691
PF12378 P1_N 309 68 24
PF12566 DUF3748 2,139 607 98
PF12657 TFIIIC_delta 2,890 1,424 664
PF12768 Rax2 2,093 1,330 609
PF12859 ANAPC1 3,505 1,733 429
PF12894 ANAPC4_WD40 39,843 18,479 7,664
PF13088 BNR_2 30,241 18,878 6,343
PF13360 PQQ_2 121,639 81,434 31,860
PF13415 Kelch_3 32,805 16,695 6,976
PF13418 Kelch_4 41,533 22,621 10,905
PF13449 Phytase-like 18,384 10,794 2,897
PF13517 FG-GAP_3 93,463 72,589 38,004
PF13540 RCC1_2 39,341 26,672 15,187
PF13570 PQQ_3 17,794 13,399 7,524
PF13854 Kelch_5 19,892 10,163 4,311
PF13859 BNR_3 5,251 2,731 671
PF13964 Kelch_6 17,046 8,405 4,251
PF13970 DUF4221 1,427 1,066 672
PF14157 YmzC 367 49 10
PF14269 Arylsulfotran_2 8,572 4,821 1,838
PF14298 DUF4374 1,149 641 171
PF14312 FG-GAP_2 7,317 6,449 5,130
PF14339 DUF4394 2,859 2,118 719
PF14583 Pectate_lyase22 1,848 1,089 243
PF14655 RAB3GAP2_N 2,828 1,502 539
PF14727 PHTB1_N 2,330 979 439
PF14761 HPS3_N 1,414 491 140
PF14779 BBS1 1,647 736 309
PF14781 BBS2_N 1,749 566 209
PF14783 BBS2_Mid 1,933 676 276
PF14870 PSII_BNR 14,529 10,267 5,857
PF15390 WDCP 1,352 299 77
PF15416 DUF4623 206 162 103
PF15492 Nbas_N 1,613 745 180
PF15525 DUF4652 192 126 88
PF15702 HPS6 747 199 47
PF15802 DCAF17 1,261 403 151
PF15869 TolB_like 2,022 953 669
PF15892 BNR_4 4,884 3,416 1,225
PF15899 BNR_6 1,010 814 464
PF15902 Sortilin-Vps10 24,855 15,504 4,284
PF15907 Itfg2 1,825 676 294
PF15911 WD40_3 1,778 745 221
PF16023 DUF4784 129 25 15
PF16261 DUF4915 2,100 1,592 528
PF16287 DUF4933 198 58 28
PF16288 DUF4934 321 82 51
PF16300 WD40_4 11,678 4,213 847
PF16465 DUF5046 62 17 9
PF16472 DUF5050 4,135 2,623 1,565
PF16529 Ge1_WD40 2,935 1,479 347
PF16687 ELYS-bb 1,453 824 265
PF16755 NUP214 473 302 162
PF16756 PALB2_WD40 978 456 113
PF16819 DUF5074 4,794 2,908 1,087
PF17005 WD40_like 104 68 52
PF17164 DUF5122 8,868 7,462 5,411
PF17170 DUF5128 13,561 8,576 5,539
PF18413 Neuraminidase 2,008 1,443 738
PF18638 CyRPA 172 48 22
PF18764 nos_propeller 18,762 5,420 216
PF18793 nos_propeller_2 3,423 1,161 51
PF18811 DPPIV_rep 875 296 36
PF18975 DUF5711 2,188 1,364 799
PF19007 DUF5736 42 26 13
PF19056 WD40_2 12,089 4,956 874
PF19193 Tectonin 3,857 2,002 845
PF19520 Dpp_8_9_N 2,860 591 69
PF20055 DUF6454 726 482 143
PF20067 SSL_N 9,410 4,745 1,388
PF20426 NBCH_WD40 9,273 4,938 864
PF20641 TAF1C_beta-prop 1,031 551 186
PF20770 PAN2_N 3,420 1,703 421
PF21029 RMC1_N 2,616 871 315
PF21030 WDR93 931 462 165
PF21031 WDR54 1,504 691 321
PF21032 PROPPIN 12,790 4,668 1,261
PF21034 BCAS3_WD40 4,658 1,803 596
PF21101 YqgU 502 297 145
PF21348 RGL11_C 5,099 3,134 819
PF21544 PorZ_N_b_propeller 3,075 2,344 888
PF21548 CATSPERB_2nd 301 158 68
PF21720 MIOS_WD40 2,548 1,059 474
PF21734 10_blade 166 142 79
PF21783 YNCE 11,459 6,112 1,906
CL0187 LysM 215,214 124,017 46,092 PF01476 LysM 199,643 118,605 44,719
PF04225 OapA 6,751 2,273 478
PF05489 Phage_tail_X 5,887 2,353 568
PF07880 T4_gp9_10 1,177 269 112
PF09215 Phage-Gp8 712 185 57
PF11246 Phage_gp53 1,056 380 203
CL0188 CH 162,770 64,517 16,530 PF00307 CH 124,592 48,507 11,638
PF03800 Nuf2 3,553 1,707 732
PF03801 Ndc80_HEC 3,748 1,757 770
PF06294 CH_2 4,250 2,499 975
PF06395 CDC24 1,799 938 278
PF10243 MIP-T3 2,097 1,062 429
PF11971 CAMSAP_CH 9,368 3,341 377
PF18383 IFT81_CH 1,783 651 264
PF19016 DUF5745 1,217 565 208
PF19047 HOOK_N 9,261 3,258 804
PF21670 HOOK_N_NuMA 1,101 340 104
CL0190 HSP20 159,736 85,171 25,070 PF00011 HSP20 114,798 63,404 18,643
PF04969 CS 31,255 14,718 4,535
PF05455 GvpH 152 122 71
PF17886 ArsA_HSP20 7,230 3,435 564
PF18201 PIH1_CS 4,130 2,300 926
PF18482 Pih1_fungal_CS 102 76 31
PF21413 SHQ1-like_CS 2,075 1,153 394
CL0191 POTRA 107,070 59,477 20,764 PF06898 YqfD 4,511 2,697 1,206
PF07244 POTRA 51,006 28,082 8,714
PF08478 POTRA_1 33,149 18,672 7,452
PF08479 POTRA_2 18,117 9,914 3,361
PF17243 POTRA_TamA_1 6,766 2,518 628
PF17287 POTRA_3 6,357 2,650 678
CL0192 GPCR_A 986,653 444,087 148,131 PF00001 7tm_1 381,107 144,169 48,393
PF00002 7tm_2 73,151 31,932 9,893
PF00003 7tm_3 47,278 21,290 6,685
PF01036 Bac_rhodopsin 13,944 5,500 1,224
PF01534 Frizzled 13,576 4,093 1,190
PF02076 STE3 3,912 2,667 1,147
PF02101 Ocular_alb 1,182 425 150
PF02117 7TM_GPCR_Sra 442 354 224
PF02118 Srg 1,833 1,544 1,063
PF02175 7TM_GPCR_Srb 192 157 88
PF03006 HlyIII 47,711 21,454 4,842
PF03125 Sre 2,061 1,729 1,302
PF03383 Serpentine_r_xa 198 151 101
PF03402 V1R 7,509 3,212 784
PF03619 Solute_trans_a 15,477 7,046 2,381
PF04080 Per1 4,609 2,299 686
PF04789 DUF621 139 122 95
PF05296 TAS2R 6,205 3,374 767
PF05462 Dicty_CAR 2,540 1,530 723
PF05875 Ceramidase 9,583 5,042 1,633
PF06454 THH1_TOM1-3_dom 3,129 1,586 569
PF06681 DUF1182 65 48 30
PF06814 Lung_7-TM_R 10,562 4,715 1,428
PF07695 7TMR-DISM_7TM 24,234 15,270 7,055
PF07698 7TM-7TMR_HD 11,878 7,531 2,285
PF10160 Tmemb_40 1,938 760 222
PF10192 GpcrRhopsn4 3,323 1,624 729
PF10292 7TM_GPCR_Srab 2,017 1,593 1,097
PF10316 7TM_GPCR_Srbc 830 699 453
PF10317 7TM_GPCR_Srd 2,366 1,984 1,366
PF10318 7TM_GPCR_Srh 4,128 3,511 2,555
PF10319 7TM_GPCR_Srj 545 428 269
PF10320 7TM_GPCR_Srsx 3,223 2,516 1,687
PF10321 7TM_GPCR_Srt 3,255 2,658 1,723
PF10322 7TM_GPCR_Sru 622 478 287
PF10323 7TM_GPCR_Srv 1,710 1,400 971
PF10324 7TM_GPCR_Srw 6,030 4,194 2,450
PF10325 7TM_GPCR_Srz 730 647 499
PF10326 7TM_GPCR_Str 4,798 3,921 2,615
PF10327 7TM_GPCR_Sri 1,003 886 676
PF10328 7TM_GPCR_Srx 3,835 3,082 2,127
PF11710 Git3 1,668 1,038 456
PF11970 GPR_Gpa2_C 2,024 1,178 506
PF12036 DUF3522 4,188 1,538 480
PF12271 Chs7 3,005 1,398 300
PF13853 7tm_4 156,443 65,287 8,625
PF13965 SID-1_RNA_chan 3,693 1,844 597
PF15100 TMEM187 327 184 82
PF16927 HisKA_7TM 12,737 9,119 5,106
PF17158 MASE4 2,251 876 340
PF17159 MASE3 3,193 2,492 1,511
PF18761 Heliorhodopsin 1,662 1,055 221
PF20684 Fung_rhodopsin 74,996 43,281 18,652
CL0193 MBB 1,303,466 698,881 231,616 PF00267 Porin_1 13,130 2,044 434
PF00577 Usher 31,028 8,580 3,024
PF00593 TonB_dep_Rec 413,465 230,214 63,199
PF01103 Omp85 75,175 42,231 13,175
PF01278 Omptin 2,038 694 361
PF01298 TbpB_B_D 2,649 1,543 864
PF01308 Chlam_OMP 2,760 290 68
PF01389 OmpA_membrane 5,259 2,208 1,008
PF01459 Porin_3 15,844 5,847 1,618
PF01617 Surface_Ag_2 7,518 1,826 458
PF01716 MSP 1,918 760 124
PF01856 HP_OMP 22,213 2,813 659
PF02253 PLA1 7,807 3,480 894
PF02264 LamB 7,540 2,200 615
PF02462 Opacity 1,113 502 185
PF02521 HP_OMP_2 4,802 322 123
PF02530 Porin_2 6,140 2,870 649
PF02722 MOSP_C 906 133 33
PF03249 TSA 1,361 223 42
PF03349 Toluene_X 24,553 13,651 4,153
PF03502 Channel_Tsx 6,427 1,334 217
PF03573 OprD 20,777 5,397 1,071
PF03687 UPF0164 1,542 1,189 712
PF03768 Attacin_N 301 143 39
PF03769 Attacin_C 646 389 158
PF03797 Autotransporter 42,720 21,621 11,071
PF03865 ShlB 18,693 10,519 3,824
PF03895 YadA_anchor 11,209 7,158 4,310
PF03922 OmpW 13,359 5,474 935
PF04338 DUF481 12,688 7,688 3,267
PF04453 LptD 18,682 9,974 2,947
PF04575 SlipAM 3,303 1,980 1,049
PF04966 OprB 17,322 9,421 3,078
PF05150 Legionella_OMP 2,258 1,592 953
PF05275 CopB 7,140 3,195 714
PF05420 BCSC_C 4,456 1,543 560
PF05538 Campylo_MOMP 1,058 361 88
PF05540 Serpulina_VSP 300 131 38
PF05736 OprF 1,338 202 65
PF06082 YjbH 6,143 2,748 951
PF06178 KdgM 4,255 680 160
PF06316 Ail_Lom 2,306 518 187
PF06629 MipA 13,486 7,078 2,466
PF06727 DUF1207 1,254 1,019 469
PF06788 UPF0257 1,201 216 63
PF06980 DUF1302 10,359 5,745 1,857
PF07017 PagP 2,164 677 166
PF07239 OpcA 91 28 20
PF07396 Porin_O_P 16,916 10,655 4,093
PF07437 YfaZ 2,503 840 321
PF07585 BBP7 1,377 1,195 807
PF07642 BBP2 7,590 5,370 1,710
PF08794 FHBP_C 1,095 288 177
PF08896 DUF1842 703 337 106
PF09381 Porin_OmpG 475 72 27
PF09411 PagL 11,253 6,909 2,616
PF09694 Gcw_chp 11,570 6,560 1,768
PF09982 LpxR 5,832 3,434 1,394
PF10082 BBP2_2 6,571 4,543 2,597
PF10626 TraO 2,559 525 136
PF10677 DUF2490 7,473 5,624 2,217
PF10895 DUF2715 168 90 60
PF11059 DUF2860 1,126 541 266
PF11231 DUF3034 1,936 1,091 179
PF11276 DUF3078 6,234 4,062 941
PF11336 DUF3138 608 211 43
PF11383 DUF3187 1,375 991 558
PF11389 Porin_OmpL1 319 90 28
PF11557 Omp_AT 413 198 88
PF11751 PorP_SprF 21,537 15,922 4,994
PF11853 DUF3373 930 676 187
PF11854 MtrB_PioB 1,482 1,168 672
PF11924 IAT_beta 7,257 2,489 1,362
PF12094 DUF3570 3,336 2,492 682
PF12097 DUF3573 160 62 17
PF12099 DUF3575 6,564 3,321 1,409
PF12519 MDM10 1,545 811 185
PF12600 DUF3769 1,008 603 223
PF13161 DUF3996 278 166 79
PF13283 NfrA_C 1,437 550 223
PF13372 Alginate_exp 12,291 7,747 2,908
PF13505 OMP_b-brl 61,077 38,404 18,092
PF13557 Phenol_MetA_deg 17,758 10,982 4,296
PF13568 OMP_b-brl_2 33,211 23,767 9,880
PF13609 Porin_4 41,672 20,189 5,626
PF13729 TraF_2 3,267 1,366 582
PF14052 Caps_assemb_Wzi 5,923 3,950 1,696
PF14121 Porin_10 4,498 3,119 1,089
PF14391 DUF4421 1,988 1,361 668
PF14905 OMP_b-brl_3 32,287 21,954 7,508
PF15283 DUF4595 677 259 181
PF16128 DUF4840 560 270 136
PF16412 DUF5020 949 543 123
PF16435 DUF5032 51 15 7
PF16518 GrlR 1,169 443 185
PF16930 Porin_5 3,562 2,093 894
PF16939 Porin_6 195 57 24
PF16941 CymA 87 28 11
PF16946 Porin_OmpG_1_2 170 52 16
PF16956 Porin_7 1,377 521 156
PF16960 HpuA 82 39 19
PF16961 OmpA_like 331 108 55
PF16966 Porin_8 1,408 339 98
PF17036 CBP_BcsS 615 455 209
PF17251 Pom 459 413 256
PF17271 Usher_TcfC 733 161 53
PF18939 DUF5686 9,129 5,829 1,718
PF18990 DUF5723 4,256 3,222 1,592
PF19089 DUF5777 3,335 2,552 634
PF19143 Omp85_2 2,625 1,574 398
PF19313 DUF5916 12,908 10,029 3,093
PF19413 YaiO 2,072 1,385 582
PF19494 DUF6029 1,933 1,486 560
PF19515 DUF6048 2,320 1,507 350
PF19572 PorV 7,569 5,259 1,208
PF19573 DUF6089 5,290 4,016 1,170
PF19577 DcaP 4,695 2,214 604
PF19783 DUF6268 2,606 1,885 794
PF19838 LptD_2 8,823 5,895 2,104
PF20230 DUF6588 1,772 1,463 642
PF20351 DUF6646 716 422 33
PF20367 DUF6662 400 274 82
PF20371 DUF6666 245 218 135
PF20507 DUF6733 160 127 36
PF20937 FHBP_N 759 44 11
PF21012 DUF6850 1,657 914 557
PF21197 PgaA_barrel 2,251 761 309
PF21620 SlpA_C 99 81 22
CL0194 DNA_pol_B-like 49,198 23,817 8,306 PF00136 DNA_pol_B 39,539 18,102 5,010
PF03175 DNA_pol_B_2 8,621 5,108 2,939
PF03337 Pox_F12L 216 39 20
PF08490 DUF1744 4,095 2,018 501
PF20286 divDNApol 175 80 48
CL0195 DBL 16,131 9,914 2,158 PF03011 PFEMP 2,777 2,322 1,308
PF05424 Duffy_binding 15,957 9,781 2,060
CL0196 DSRM 160,554 67,409 14,972 PF00035 dsrm 83,773 39,499 9,635
PF00333 Ribosomal_S5 57,236 18,674 2,176
PF03368 Dicer_dimer 7,895 3,985 1,251
PF04098 Rad52_Rad22 5,988 3,301 1,332
PF14709 DND1_DSRM 5,016 1,871 494
PF14954 LIX1 1,793 527 103
PF16482 Staufen_C 3,784 1,035 231
PF17842 dsRBD2 529 228 77
PF17895 Dicer_N 6 3 1
PF20932 Dicer_dsRBD 2,202 1,002 326
CL0197 GME 72,844 34,406 6,722 PF01912 eIF-6 7,102 2,851 729
PF02274 ADI 17,096 7,033 1,276
PF03068 PAD 4,188 1,920 559
PF04371 PAD_porph 22,599 11,630 2,342
PF04996 AstB 6,413 2,017 218
PF19420 DDAH_eukar 14,439 8,387 1,467
PF21778 DUF6873 1,046 726 336
CL0198 HHH 823,812 405,808 77,909 PF00633 HHH 75,412 38,147 5,021
PF00730 HhH-GPD 140,600 76,909 12,046
PF02371 Transposase_20 57,116 31,618 10,514
PF03118 RNA_pol_A_CTD 60,353 15,961 2,393
PF03934 T2SSK 7,523 3,957 1,224
PF04919 DUF655 3,300 1,847 273
PF04994 TfoX_C 5,930 2,727 634
PF06514 PsbU 1,018 543 109
PF10391 DNA_pol_lambd_f 7,383 3,576 1,115
PF11372 DUF3173 1,122 340 107
PF11731 Cdd1 2,201 1,514 319
PF11798 IMS_HHH 36,000 16,564 2,428
PF12482 DUF3701 1,464 822 218
PF12826 HHH_2 53,111 27,300 3,561
PF12836 HHH_3 74,949 40,898 13,271
PF14229 DUF4332 4,236 2,874 892
PF14490 HHH_4 15,222 7,861 1,749
PF14520 HHH_5 164,794 82,026 14,456
PF14579 HHH_6 77,983 38,529 5,652
PF14635 HHH_7 4,392 1,932 493
PF14716 HHH_8 23,279 13,398 2,655
PF17674 HHH_9 32,274 12,807 1,173
PF18094 DNA_pol_B_N 1,601 768 74
PF20582 UPF0758_N 28,585 15,009 2,116
PF21016 RlmN_N 37,254 15,995 1,629
PF21102 DprA_N 4,497 2,809 283
PF21176 RecR_HhH 41,307 17,100 1,002
PF21292 EME1-MUS81_C 3,908 2,042 818
PF21616 Topo-V_HhH_2_2nd 2 2 1
PF21687 T2SSK_1st 11,777 7,224 2,712
PF21698 Spo16_C 38 24 14
PF21704 POLH-Rev1_HhH 5,510 2,700 763
PF21790 OGG 914 679 355
PF21794 RAD51D_N 1,064 459 123
CL0199 DPBB 480,631 253,125 56,315 PF00967 Barwin 1,522 863 341
PF01568 Molydop_binding 142,326 63,074 7,873
PF02015 Glyco_hydro_45 2,178 1,328 414
PF02261 Asp_decarbox 22,983 9,210 591
PF02359 CDC48_N 16,249 6,163 922
PF03330 DPBB_1 49,812 26,525 7,336
PF06725 3D 26,111 13,770 3,730
PF07249 Cerato-platanin 2,217 1,264 335
PF09263 PEX-2N 1,163 453 54
PF12704 MacB_PCD 216,060 130,478 34,762
CL0200 Prefoldin 33,395 16,889 5,242 PF01920 Prefoldin_2 17,718 8,735 2,462
PF02996 Prefoldin 14,761 7,681 2,686
PF13758 Prefoldin_3 913 473 94
CL0201 Peptidase_SH 21,075 11,414 4,478 PF00716 Peptidase_S21 850 113 56
PF03420 Peptidase_S77 1,371 591 204
PF04586 Peptidase_S78 13,880 8,272 3,069
PF09979 DUF2213 3,335 1,473 606
PF14550 Peptidase_S78_2 1,459 884 504
PF20034 Peptidase_S80 174 84 47
CL0202 GBD 608,669 326,829 106,132 PF00052 Laminin_B 11,554 6,334 1,671
PF00055 Laminin_N 21,230 10,284 1,822
PF00754 F5_F8_type_C 93,734 50,543 19,226
PF01067 Calpain_III 21,038 8,370 2,073
PF01404 Ephrin_lbd 18,966 5,135 690
PF01483 P_proprotein 27,438 15,250 5,726
PF01834 XRCC1_N 2,249 1,162 447
PF02018 CBM_4_9 18,624 11,578 5,635
PF02837 Glyco_hydro_2_N 69,037 39,409 9,349
PF03170 BcsB 7,000 3,121 1,252
PF03256 ANAPC10 10,025 4,812 1,067
PF03422 CBM_6 19,387 12,405 4,113
PF03424 CBM_17_28 109 75 23
PF03425 CBM_11 2,111 1,478 803
PF03426 CBM_15 26 21 11
PF03505 Clenterotox 89 13 9
PF03561 Allantoicase 8,443 3,666 614
PF03944 Endotoxin_C 1,210 533 249
PF04151 PPC 17,126 10,634 5,617
PF04300 FBA 4,035 1,877 675
PF04620 FlaA 1,347 631 202
PF04721 PAW 1,590 701 285
PF04862 DUF642 4,453 2,391 1,047
PF06201 PITH 8,019 3,759 1,045
PF06366 FlhE 1,581 531 160
PF06588 Muskelin_N 2,081 715 258
PF07696 7TMR-DISMED2 15,198 9,158 4,206
PF07738 Sad1_UNC 15,935 7,922 3,154
PF07828 PA-IL 249 165 77
PF08305 NPCBM 8,948 6,349 2,884
PF08530 PepX_C 39,492 22,789 4,670
PF08531 Bac_rhamnosid_N 17,228 11,558 3,101
PF08547 CIA30 10,197 6,218 2,117
PF08980 DUF1883 2,046 668 149
PF09092 Lyase_N 1,179 498 196
PF09144 YpM 4 2 1
PF09212 CBM27 213 140 80
PF11721 Malectin 14,261 8,540 3,501
PF12103 Lipl32 579 102 21
PF12819 Malectin_like 17,946 9,410 3,097
PF13201 PCMD 3,059 1,511 604
PF13364 BetaGal_ABD2 5,329 3,064 864
PF14324 PINIT 7,275 2,431 773
PF14607 GxDLY 2,573 1,763 578
PF14683 CBM-like 6,772 3,431 779
PF14717 DUF4465 1,465 974 541
PF14896 Arabino_trans_C 3,432 1,440 200
PF15425 DUF4627 144 35 27
PF16391 DUF5000 1,450 1,023 337
PF16824 CBM_26 1,065 148 31
PF16841 CBM60 1,907 1,401 809
PF16871 DUF5077 1,295 969 234
PF16990 CBM_35 5,007 3,146 1,045
PF17829 GH115_C 5,641 3,521 879
PF17991 Thioredoxin_10 4,359 2,584 529
PF17992 Agarase_CBM 909 371 70
PF17993 HA70_C 49 4 1
PF17994 Glft2_N 3,894 1,497 290
PF17996 CE2_N 3,690 2,600 965
PF17997 Cry1Ac_D5 714 311 108
PF17999 PulA_N1 1,020 315 72
PF18040 BPA_C 425 348 172
PF18099 CBM_35_2 911 704 418
PF18259 CBM65_1 135 90 53
PF18276 TcA_TcB_BD 2,491 1,823 982
PF18329 SGBP_B_XBD 1,083 668 227
PF18344 CBM32 325 92 29
PF18448 CBM46 741 486 93
PF18539 DUF5625 241 154 76
PF18559 Exop_C 2,764 1,708 299
PF18560 Lectin_like 2,234 1,496 968
PF21038 CEP104_N 2,367 1,164 463
PF21104 Glyco_hydro_78_N 982 503 100
PF21114 DDR1-2_DS-like 4,808 2,277 638
PF21174 Glce_b_sandwich 1,290 388 103
PF21181 SsfX3_N 1,586 959 124
PF21199 LAMININ_IV_B 4,939 2,228 320
PF21253 Mann_GBD_bact 367 282 148
PF21254 AGA-YXIM_GBD 1,069 737 238
PF21316 TPPII_GBD 3,065 1,181 365
PF21317 BetaGal_ABD_1 12,393 5,559 1,019
PF21463 Cry1Ac_dom-VII 601 249 62
PF21466 GH101_dom-5 1,460 591 175
PF21467 BetaGal_gal-bd 19,688 8,774 1,848
PF21471 Reelin_subrepeat-B 2,143 1,089 634
PF21557 RhaB_D2 157 132 30
PF21582 CBM30 409 290 183
PF21606 BgaA-like_CBM 617 131 71
PF21615 CBM-like_2 16 5 4
CL0203 CBD 40,828 25,677 9,715 PF00553 CBM_2 24,101 14,418 3,001
PF00942 CBM_3 3,679 2,030 686
PF00963 Cohesin 9,542 7,611 5,559
PF03173 CHB_HEX 2,642 1,249 314
PF09478 CBM49 1,365 671 254
CL0204 Adhesin 72,049 24,955 9,704 PF00419 Fimbrial 45,090 13,004 4,739
PF03627 PapG_N 97 18 11
PF04619 Adhesin_Dr 69 10 8
PF05229 SCPU 10,070 4,727 1,831
PF05737 Collagen_bind 3,724 1,765 1,027
PF05775 AfaD 652 59 45
PF06551 DUF1120 3,211 1,589 415
PF09160 FimH_man-bind 1,080 190 72
PF09222 Fim-adh_lectin 34 9 6
PF09255 Antig_Caf1 25 6 6
PF09460 Saf-Nte_pilin 1,041 57 14
PF10425 SdrG_C_C 1,342 535 284
PF16364 Antigen_C 1,137 394 166
PF16569 GramPos_pilinBB 2,415 1,408 721
PF16970 FimA 1,952 908 265
PF17998 AgI_II_C2 1,449 566 249
PF20595 pAdhesive_6 17 18 14
PF20623 Sgo0707_N2 346 184 87
PF21462 PsaS 26 8 5
CL0205 Di-copper 32,468 16,300 6,065 PF00264 Tyrosinase 29,126 14,269 5,377
PF00372 Hemocyanin_M 3,344 2,035 692
CL0207 Rhomboid-like 120,563 67,661 19,687 PF01694 Rhomboid 104,282 60,341 17,625
PF04511 DER1 10,191 4,254 1,346
PF08551 DUF1751 3,680 1,718 492
PF20401 Rhomboid_2 2,406 1,360 264
CL0208 UBC 161,543 66,264 20,118 PF00179 UQ_con 118,188 45,694 13,011
PF05743 UEV 5,987 2,604 883
PF05773 RWD 23,891 11,100 3,519
PF08694 UFC1 1,772 643 181
PF09765 FANCL_d1 1,278 527 174
PF14457 Prok-E2_A 805 559 295
PF14459 Prok-E2_C 231 55 31
PF14460 Prok-E2_D 2,097 1,088 417
PF14461 Prok-E2_B 774 561 325
PF14462 Prok-E2_E 850 605 236
PF18210 Knl1_RWD_C 2,676 1,376 460
PF18890 FANCL_d2 1,991 855 275
PF18891 FANCL_d3 2,242 1,003 356
PF20298 E2-ntca 112 91 47
PF21539 Med15_C 2,066 857 320
CL0209 Bet_v_1_like 422,699 223,851 52,521 PF00407 Bet_v_1 10,437 5,197 1,632
PF00848 Ring_hydroxyl_A 47,125 21,384 4,064
PF01852 START 41,544 16,962 5,118
PF02121 IP_trans 10,841 4,677 977
PF02713 DUF220 872 400 127
PF03364 Polyketide_cyc 39,577 21,145 4,980
PF04707 PRELI 11,710 4,589 1,333
PF06240 COXG 14,682 9,318 2,056
PF06804 Lipoprotein_18 8,360 3,460 863
PF08327 AHSA1 79,397 50,066 10,012
PF08417 PaO 3,393 1,838 515
PF08982 AtaL 2,483 1,354 332
PF10604 Polyketide_cyc2 80,741 47,998 12,913
PF10698 DUF2505 4,819 2,707 780
PF11066 DUF2867 13,193 7,231 1,114
PF11274 DUF3074 2,228 1,350 456
PF11485 STK_08120-like 166 94 52
PF11687 DUF3284 1,072 393 199
PF11723 Aromatic_hydrox 571 325 82
PF12723 DUF3809 108 74 24
PF16016 VASt 12,753 5,465 1,957
PF16797 Fungal_KA1 1,182 637 148
PF18089 DAPG_hydrolase 1,589 921 305
PF19112 VanA_C 16,967 8,173 1,611
PF19298 KshA_C 7,186 3,216 756
PF19299 DUF5914 1,296 692 36
PF19301 LigXa_C 4,495 2,637 455
PF19569 START_2 3,386 1,615 191
PF20670 DUF6816 1,004 682 305
CL0210 HNOX-like 38,327 19,920 6,233 PF02830 V4R 7,969 5,119 1,699
PF03500 Cellsynth_D 734 347 118
PF04051 TRAPP 12,550 4,658 1,210
PF06505 XylR_N 2,839 1,590 397
PF07700 HNOB 9,573 5,271 1,582
PF14196 ATC_hydrolase 5,643 3,463 1,327
PF18546 MetOD1 1,740 984 267
CL0212 SNARE 6,367 2,723 824 PF07919 Gryzun 1,455 760 249
PF12584 TRAPPC10 3,519 1,553 466
PF12742 Gryzun-like 1,415 436 135
CL0213 ShK-like 14,593 9,999 5,900 PF01549 ShK 12,774 9,052 5,651
PF08562 Crisp 1,817 947 249
CL0214 UBA 218,760 94,450 23,527 PF00627 UBA 51,122 20,688 5,649
PF02845 CUE 19,536 8,651 2,824
PF03474 DMA 2,275 1,007 340
PF03765 CRAL_TRIO_N 26,443 11,314 2,778
PF03943 TAP_C 3,799 1,937 658
PF06972 GIP1_N 2,731 1,101 359
PF07223 DUF1421 1,348 603 181
PF07499 RuvA_C 40,065 19,176 2,644
PF08587 UBA_2 1,423 614 79
PF08938 HBS1_N 3,247 1,434 393
PF09145 Ubiq-assoc 56 43 22
PF09288 UBA_3 1,256 531 79
PF10440 WIYLD 1,865 930 448
PF11547 E3_UbLigase_EDD 2,227 1,044 196
PF14555 UBA_4 22,242 9,237 3,118
PF16577 UBA_5 1,150 449 150
PF16678 HOIP-UBA 1,453 685 256
PF18039 UBA_6 3,615 1,149 251
PF18091 E3_UbLigase_RBR 1,570 785 289
PF18561 Regnase_1_C 2,644 707 133
PF19026 HYPK_UBA 10,804 4,906 1,210
PF20741 GKRP-like_C 4,318 2,093 356
PF21115 UBA_BRSK 3,567 1,904 267
PF21147 AMPK_alpha_AID 2,750 599 116
PF21235 ARI1_UBAl 6,061 2,616 749
PF21267 UBAP-1_UBA2 1,874 565 118
PF21290 BIRC2-3-like_UBA 2,014 508 113
PF21594 MELK_UBA 1,351 462 117
CL0217 Rotavirus_VP7 19,301 902 99 PF00434 VP7 18,860 816 80
PF05868 Rotavirus_VP7 439 86 19
CL0219 RNase_H 1,836,830 1,050,740 412,248 PF00075 RNase_H 102,975 45,664 14,765
PF00665 rve 245,513 123,041 53,278
PF00872 Transposase_mut 37,978 20,431 8,990
PF00929 RNase_T 159,237 77,084 17,131
PF01351 RNase_HII 56,950 31,548 5,069
PF01359 Transposase_1 5,618 4,287 2,569
PF01385 OrfB_IS605 45,376 21,812 5,104
PF01526 DDE_Tnp_Tn3 15,505 6,811 3,320
PF01609 DDE_Tnp_1 101,932 55,443 22,267
PF01610 DDE_Tnp_ISL3 34,207 18,109 8,230
PF01612 DNA_pol_A_exo1 85,975 44,433 11,453
PF01949 DUF99 2,689 1,878 408
PF02075 RuvC 39,866 19,666 2,678
PF02171 Piwi 30,864 14,786 5,552
PF02281 Dimer_Tnp_Tn5 1,633 1,027 524
PF02482 Ribosomal_S30AE 49,295 24,121 4,726
PF02870 Methyltransf_1N 25,049 12,815 2,159
PF02914 DDE_2 903 628 262
PF02992 Transposase_21 9,220 7,210 4,517
PF03050 DDE_Tnp_IS66 34,452 19,834 9,308
PF03104 DNA_pol_B_exo1 31,257 15,116 3,953
PF03184 DDE_1 31,828 22,003 13,059
PF03400 DDE_Tnp_IS1 8,001 3,491 1,265
PF04250 DUF429 7,479 4,991 1,612
PF04308 RNaseH_like 3,377 1,845 263
PF04493 Endonuclease_5 12,982 7,678 1,927
PF04693 DDE_Tnp_2 609 399 240
PF04827 Plant_tran 4,441 3,662 2,158
PF04848 Pox_A22 339 180 90
PF04857 CAF1 14,707 6,154 2,211
PF06782 UPF0236 3,364 1,973 1,254
PF06869 DUF1258 806 452 355
PF07066 DUF3882 370 26 15
PF07592 DDE_Tnp_ISAZ013 4,343 3,234 1,423
PF08459 UvrC_RNaseH_dom 47,873 22,599 3,238
PF09153 MGMT_N 78 45 3
PF09159 Ydc2-catalyt 1,042 745 383
PF09281 Taq-exonuc 130 70 11
PF09376 NurA 5,736 3,807 1,491
PF10108 DNA_pol_B_exo2 8,900 4,821 775
PF10551 MULE 36,838 24,280 13,949
PF11074 DUF2779 3,252 2,523 1,082
PF12762 DDE_Tnp_IS1595 16,293 10,763 4,465
PF13017 Maelstrom 1,353 741 429
PF13031 DUF3892 3,057 1,915 572
PF13333 rve_2 49,456 24,281 7,835
PF13358 DDE_3 68,584 39,750 15,993
PF13359 DDE_Tnp_4 46,445 31,766 17,272
PF13456 RVT_3 64,770 52,018 30,478
PF13482 RNase_H_2 16,515 11,025 3,555
PF13546 DDE_5 13,743 9,085 3,895
PF13586 DDE_Tnp_1_2 9,702 6,006 2,468
PF13610 DDE_Tnp_IS240 19,652 9,427 2,821
PF13612 DDE_Tnp_1_3 7,186 3,948 1,648
PF13680 DUF4152 167 106 26
PF13683 rve_3 47,843 29,470 12,178
PF13701 DDE_Tnp_1_4 12,526 7,813 3,362
PF13737 DDE_Tnp_1_5 7,164 2,760 1,142
PF13751 DDE_Tnp_1_6 18,543 11,068 4,756
PF13843 DDE_Tnp_1_7 23,852 17,788 12,076
PF16473 Rv2179c-like 5,720 2,328 784
PF17288 Terminase_3C 4,194 2,184 552
PF17289 Terminase_6C 18,534 9,199 2,865
PF17290 Arena_ncap_C 1,678 164 19
PF17738 DUF5575 325 155 41
PF17917 RT_RNaseH 63,818 51,455 30,022
PF17919 RT_RNaseH_2 65,300 53,357 32,581
PF18049 DNA_pol_P_Exo 780 353 108
PF18516 RuvC_1 280 209 124
PF18758 KDZ 10,549 9,138 5,185
PF18759 Plavaka 10,300 8,903 4,736
PF20441 TerL_nuclease 13,329 5,979 1,484
PF20700 Mutator 8,637 6,620 4,162
PF21056 ZSWIM1-3_RNaseH-like 4,358 2,979 2,106
PF21762 DEDDh_C 3,101 2,172 1,214
PF21787 TNP-like_RNaseH_N 5,364 4,435 3,433
PF21789 TNP-like_RNaseH_C 2,745 2,138 1,612
PF21804 Transposase_29 726 590 349
CL0220 EF_hand 598,101 268,263 96,494 PF00036 EF-hand_1 26,948 11,512 5,148
PF00404 Dockerin_1 26,533 22,550 16,691
PF00612 IQ 87,258 41,122 12,986
PF01023 S_100 11,731 4,663 1,465
PF02761 Cbl_N2 3,890 1,416 269
PF03556 Cullin_binding 10,988 4,033 1,285
PF05042 Caleosin 3,534 1,947 604
PF05517 p25-alpha 4,250 2,009 838
PF08356 EF_assoc_2 7,155 2,265 417
PF08414 NADPH_Ox 3,345 1,362 260
PF08726 EFhand_Ca_insen 11,490 3,568 346
PF08763 Ca_chan_IQ 16,393 10,032 1,007
PF08976 EF-hand_11 1,055 384 178
PF09068 EF-hand_2 12,717 4,845 819
PF09069 EF-hand_3 13,324 4,919 815
PF09279 EF-hand_like 20,424 8,138 1,249
PF10591 SPARC_Ca_bdg 9,667 3,193 863
PF12354 Internalin_N 1,090 163 68
PF12763 EF-hand_4 25,342 9,962 2,554
PF13202 EF-hand_5 70,549 40,342 19,779
PF13405 EF-hand_6 22,910 10,231 5,021
PF13499 EF-hand_7 241,823 99,398 35,811
PF13833 EF-hand_8 37,950 15,643 5,874
PF14513 DAG_kinase_N 4,510 1,552 238
PF14658 EF-hand_9 1,463 605 173
PF14788 EF-hand_10 1,435 512 101
PF15157 IQCJ-SCHIP1 729 351 102
PF17743 DUF5580 296 130 57
PF17901 EF-hand_12 48 47 36
PF17958 EF-hand_13 5,769 2,068 612
PF17959 EF-hand_14 4,378 1,695 321
PF17974 GalBD_like 1,495 617 191
PF19914 WEF-hand 1,308 421 85
PF20742 DUF5580_M 474 190 81
PF21008 AIF-1 2,082 687 138
PF21116 EF-hand_Zip 1,589 556 177
PF21161 P2R3B_EF-hand 2,896 1,005 216
PF21354 STAT_linker 9,609 2,744 476
PF21521 MYO6_lever 3,026 858 139
PF21550 MTIP_N 114 33 14
CL0221 RRM 677,894 291,103 90,878 PF00076 RRM_1 548,172 233,088 75,542
PF02994 Transposase_22 4,433 1,901 581
PF03467 Smg4_UPF3 5,487 2,607 971
PF03468 XS 3,860 1,956 711
PF03880 DbpA 33,820 14,396 1,865
PF04059 RRM_2 6,966 3,932 2,102
PF04847 Calcipressin 5,236 2,015 521
PF05172 Nup35_RRM 2,896 1,459 625
PF07576 BRAP2 4,223 1,990 615
PF08152 GUCT 3,207 1,329 386
PF08489 DUF1743 2,626 1,661 339
PF08675 RNA_bind 1,739 605 178
PF08777 RRM_3 3,845 1,595 632
PF08952 DUF1866 3,663 1,744 176
PF09162 Tap-RNA_bind 2,365 1,129 365
PF11608 MARF1_RRM1 1,643 640 125
PF11767 SET_assoc 1,300 659 195
PF11835 RRM_8 11,456 3,142 737
PF12220 U1snRNP70_N 3,549 1,776 464
PF13893 RRM_5 13,633 3,792 1,002
PF14605 Nup35_RRM_2 949 416 169
PF14703 PHM7_cyt 19,593 8,940 2,332
PF15023 DUF4523 243 152 68
PF15407 Spo7_2_N 608 344 96
PF16367 RRM_7 8,296 2,858 690
PF16842 RRM_occluded 1,114 545 155
PF17774 YlmH_RBD 7,626 3,571 940
PF17797 RL 980 324 93
PF17799 RRM_Rrp7 1,920 1,060 239
PF18440 GlcNAc-1_reg 1,284 364 50
PF18444 RRM_9 298 211 79
PF18528 Ret2_MD 49 20 4
PF19977 xRRM 279 228 140
PF20846 PNMA_N 1,682 817 289
PF20991 CBP66_1st 38 21 7
PF21569 SET1_RBD 140 69 33
CL0222 MviN_MATE 342,176 190,477 65,647 PF01554 MatE 175,598 87,236 21,358
PF01943 Polysacc_synt 69,831 43,490 20,923
PF03023 MurJ 44,193 25,083 6,529
PF04506 Rft-1 4,499 2,269 852
PF07260 ANKH 1,492 467 177
PF13440 Polysacc_synt_3 37,007 25,886 13,791
PF14667 Polysacc_synt_C 67,199 43,564 20,175
PF16933 PelG 2,141 1,076 392
CL0223 MACRO 115,246 56,733 13,291 PF01661 Macro 57,919 27,159 6,596
PF02789 Peptidase_M17_N 35,145 17,338 3,000
PF05028 PARG_cat_C 4,713 2,590 1,196
PF10021 PARG_cat_microb 6,911 3,963 1,345
PF10154 DUF2362 1,947 730 342
PF11633 bCoV_SUD_M 5,046 252 16
PF14519 Macro_2 223 167 95
PF18295 Pdase_M17_N2 1,475 669 171
PF20016 ThsA_Macro 957 657 279
PF21337 Peptidase_M17_N_1 5,896 3,444 287
CL0224 DHQS 219,700 104,430 15,964 PF00465 Fe-ADH 103,713 45,708 8,149
PF00731 AIRC 57,694 27,927 1,866
PF01761 DHQ_synthase 50,543 26,758 4,934
PF13685 Fe-ADH_2 7,752 4,044 1,023
CL0225 FtsL 58,111 31,464 10,713 PF04977 DivIC 40,010 22,524 8,089
PF04999 FtsL 10,311 4,875 1,434
PF06005 ZapB 3,716 1,617 646
PF19579 FtsL_2 4,070 2,465 648
CL0226 M6PR 18,646 9,440 3,499 PF00878 CIMR 1,980 1,104 363
PF02157 Man-6-P_recep 2,700 1,243 465
PF07915 PRKCSH 6,548 2,948 1,077
PF09451 ATG27 2,776 1,767 793
PF13015 PRKCSH_1 4,694 2,492 958
CL0227 Enolase_N 183,899 77,999 9,218 PF02746 MR_MLE_N 110,642 50,959 6,675
PF03952 Enolase_N 63,137 22,077 1,775
PF05034 MAAL_N 1,587 748 91
PF18374 Enolase_like_N 3,969 2,268 130
PF21508 MenC_N 4,559 1,951 569
CL0228 Acyltransferase 293,459 151,568 38,433 PF01553 Acyltransferase 210,338 106,853 25,493
PF03279 Lip_A_acyltrans 52,585 27,728 7,872
PF03982 DAGAT 13,384 6,882 2,515
PF04028 DUF374 8,503 5,516 1,848
PF19576 Acyltransf_2 8,655 4,651 814
CL0229 RING 1,207,300 546,366 183,616 PF00097 zf-C3HC4 81,707 35,420 15,567
PF00130 C1_1 91,721 36,638 6,719
PF00569 ZZ 42,426 19,291 5,874
PF00628 PHD 120,296 55,352 18,233
PF01363 FYVE 68,248 28,581 8,733
PF01428 zf-AN1 19,823 9,059 2,959
PF01485 IBR 40,393 20,768 9,150
PF02132 RecR_ZnF 36,712 14,379 794
PF02148 zf-UBP 36,236 15,591 3,212
PF02318 FYVE_2 13,808 6,347 1,420
PF02891 zf-MIZ 14,663 5,549 2,062
PF03107 C1_2 10,800 6,685 2,930
PF03854 zf-P11 618 130 23
PF04564 U-box 42,741 19,125 6,899
PF04641 Rtf2 5,223 2,684 811
PF05290 Baculo_IE-1 121 61 31
PF05715 zf-piccolo 1,894 1,075 313
PF05883 Baculo_RING 145 72 19
PF06416 T3SS_NleG 748 133 57
PF07227 PHD_Oberon 3,687 1,586 415
PF07496 zf-CW 11,332 4,964 1,808
PF07800 DUF1644 3,070 1,393 420
PF07975 C1_4 3,057 1,246 237
PF08746 zf-RING-like 2,873 1,345 399
PF09416 UPF1_Zn_bind 3,925 1,409 345
PF11789 zf-Nse 3,696 2,046 968
PF11793 FANCL_C 2,103 915 320
PF12678 zf-rbx1 8,471 3,953 1,770
PF12861 zf-ANAPC11 3,575 1,878 829
PF12906 RINGv 30,929 14,007 5,140
PF13341 RAG2_PHD 2,512 267 33
PF13445 zf-RING_UBOX 65,168 31,510 12,568
PF13639 zf-RING_2 176,509 90,231 39,549
PF13771 zf-HC5HC2H 14,496 7,180 2,515
PF13831 PHD_2 23,842 9,571 2,332
PF13832 zf-HC5HC2H_2 30,322 13,230 3,399
PF13901 RH_dom 7,758 3,332 1,010
PF13920 zf-C3HC4_3 80,076 36,206 14,480
PF13923 zf-C3HC4_2 45,184 19,912 7,933
PF14445 Prok-RING_2 98 80 40
PF14446 Prok-RING_1 907 714 521
PF14447 Prok-RING_4 565 309 104
PF14569 zf-UDP 4,699 2,043 265
PF14570 zf-RING_4 7,701 3,357 920
PF14634 zf-RING_5 9,237 4,554 2,351
PF14835 zf-RING_6 1,044 404 108
PF15227 zf-C3HC4_4 23,087 12,478 4,122
PF15446 zf-PHD-like 1,035 579 133
PF15906 zf-NOSIP 3,236 1,203 322
PF16685 zf-RING_10 1,244 341 117
PF16744 zf-RING_15 969 271 66
PF16866 PHD_4 5,515 2,112 290
PF17034 zinc_ribbon_16 2,803 1,226 457
PF17120 zf-RING_16 3,247 1,675 623
PF17121 zf-C3HC4_5 2,641 1,219 278
PF17122 zf-C3H2C3 1,192 608 161
PF17123 zf-RING_11 6,134 3,718 2,024
PF17807 zf-UBP_var 4,996 2,110 398
PF17976 zf-RING_12 1,350 575 177
PF17977 zf-RING_13 62 3 2
PF17978 zf-RING_14 1,512 662 216
PF17980 ADD_DNMT3 4,585 2,071 305
PF17981 ADD_ATRX 2,437 1,279 354
PF17982 C5HCH 4,017 1,915 332
PF18716 VATC 1,481 808 292
PF20723 Pellino_RING 3,031 809 159
PF20826 PHD_5 9,475 4,604 1,583
PF21202 SLX1_C 2,424 1,464 510
PF21255 ADDz_Dnmt3b 4,679 2,125 322
PF21257 PHD_ash2p_like 269 48 10
PF21272 FYVE_CARP1-2 2,108 565 66
PF21362 Sina_RING 9,120 3,452 1,518
PF21363 TRAF3_RING 2,083 401 123
PF21369 STL11_N 3,928 1,469 416
CL0230 HO 59,664 29,232 6,183 PF01126 Heme_oxygenase 14,995 7,621 2,086
PF03070 TENA_THI-4 25,044 11,538 2,037
PF11251 DUF3050 3,318 1,929 371
PF12981 DUF3865 84 44 29
PF14518 Haem_oxygenas_2 16,227 8,138 1,715
CL0231 MazG 113,647 58,390 8,425 PF01503 PRA-PH 44,054 20,313 2,361
PF03819 MazG 50,856 28,003 4,266
PF04447 dATP-dGTP_PPHyd 936 499 262
PF08761 dUTPase_2 4,908 2,579 554
PF12643 MazG-like 12,366 7,062 1,111
PF18595 Nuf2_DHR10-like 1,541 717 276
CL0232 NifU 112,164 52,746 6,509 PF01106 NifU 40,020 18,534 2,686
PF01883 FeS_assembly_P 72,143 34,213 3,824
CL0233 SufE_NifU 139,984 71,063 11,211 PF01592 NifU_N 48,988 23,239 3,338
PF02657 SufE 21,835 10,409 1,295
PF03450 CO_deh_flav_C 58,925 33,082 5,503
PF10437 Lip_prot_lig_C 10,232 4,333 1,075
CL0234 CTPT 61,139 32,133 8,702 PF01148 CTP_transf_1 57,338 29,660 8,004
PF01864 CarS-like 3,799 2,473 699
CL0235 PspA 66,890 27,629 6,598 PF03357 Snf7 33,291 13,170 3,510
PF03398 Ist1 8,416 4,161 1,399
PF04012 PspA_IM30 25,180 10,298 1,689
CL0236 PDDEXK 927,586 502,737 161,608 PF00603 Flu_PA 99,640 563 118
PF01646 Herpes_UL24 533 115 66
PF01771 Viral_alk_exo 1,100 565 407
PF01870 Hjc 3,108 1,938 644
PF01930 Cas_Cas4 11,696 8,151 2,028
PF01939 NucS_C 8,939 3,865 993
PF01974 tRNA_int_endo 10,786 6,349 1,922
PF02021 UPF0102 38,359 23,712 5,987
PF02646 RmuC 32,094 17,513 4,085
PF02732 ERCC4 16,082 9,149 3,127
PF02923 BamHI 214 161 50
PF02963 EcoRI 396 202 50
PF02976 MutH 4,144 1,727 366
PF03008 DUF234 7,353 4,364 1,353
PF03749 SfsA 13,485 7,499 1,306
PF03834 Rad10 3,637 2,075 619
PF03838 RecU 5,378 2,431 407
PF03852 Vsr 11,379 8,163 1,586
PF03871 RNA_pol_Rpb5_N 4,892 1,801 450
PF04313 HSDR_N 35,532 19,752 3,393
PF04411 PDDEXK_7 1,900 1,406 699
PF04471 Mrr_cat 31,857 21,981 9,564
PF04480 DUF559 26,592 19,987 7,462
PF04555 XhoI 868 658 169
PF04556 DpnII 1,725 1,027 325
PF04754 Transposase_31 13,301 5,398 2,477
PF05091 eIF-3_zeta 4,511 1,595 517
PF05367 Phage_endo_I 847 448 158
PF05685 Uma2 80,843 52,551 12,435
PF06023 Csa1 470 360 151
PF06044 DpnI 786 547 162
PF06054 CoiA 5,560 3,172 1,825
PF06250 YhcG_C 14,276 8,331 1,514
PF06300 Tsp45I 486 275 97
PF06319 MmcB-like 4,296 2,375 327
PF06356 DUF1064 2,437 1,405 574
PF06616 BsuBI_PstI_RE 1,660 1,140 274
PF07147 PDCD9 2,524 1,178 371
PF07152 YaeQ 8,295 3,122 376
PF07788 PDDEXK_10 1,102 775 361
PF07832 Bse634I 103 87 40
PF08011 PDDEXK_9 13,468 7,285 2,016
PF08373 RAP 8,045 3,588 1,540
PF08378 NERD 21,609 14,852 6,583
PF08634 Pet127 1,597 1,068 527
PF08652 RAI1 3,452 1,971 763
PF08682 DUF1780 907 87 34
PF08696 Dna2 4,228 2,199 816
PF08722 Tn7_TnsA-like_N 6,018 3,475 1,626
PF08769 Spo0A_C 6,580 3,247 972
PF08774 VRR_NUC 11,527 5,662 2,125
PF08814 XisH 3,621 2,046 575
PF08862 DUF1829 805 512 217
PF08877 MepB-like 2,429 1,412 361
PF09002 DUF1887 1,623 1,037 619
PF09015 NgoMIV_restric 522 411 110
PF09019 EcoRII-C 1,459 818 273
PF09126 NaeI 590 497 133
PF09194 Endonuc-BsobI 360 240 75
PF09195 Endonuc-BglII 1,560 1,279 277
PF09208 Endonuc-MspI 47 36 25
PF09225 Endonuc-PvuII 163 119 39
PF09226 Endonuc-HincII 63 49 16
PF09233 Endonuc-EcoRV 567 422 122
PF09254 FokI_cleav_dom 236 182 82
PF09455 Cas_DxTHG 1,845 1,524 1,031
PF09491 RE_AlwI 1,224 713 320
PF09499 RE_ApaLI 198 139 36
PF09504 RE_Bsp6I 73 52 20
PF09516 RE_CfrBI 518 238 69
PF09518 RE_HindIII 207 141 60
PF09519 RE_HindVP 293 184 71
PF09520 RE_TdeIII 1,114 830 210
PF09521 RE_NgoPII 346 252 76
PF09549 RE_Bpu10I 333 229 80
PF09553 RE_Eco47II 646 454 138
PF09554 RE_HaeII 167 128 49
PF09561 RE_HpaII 866 468 213
PF09562 RE_LlaMI 62 49 19
PF09563 RE_LlaJI 749 450 258
PF09564 RE_NgoBV 244 148 61
PF09566 RE_SacI 319 266 138
PF09568 RE_MjaI 717 547 134
PF09569 RE_ScaI 150 101 39
PF09570 RE_SinI 198 127 60
PF09571 RE_XcyI 257 209 93
PF09572 RE_XamI 455 363 102
PF09573 RE_TaqI 116 83 35
PF09588 YqaJ 14,935 8,785 4,367
PF09623 Cas_NE0113 1,365 1,141 573
PF09631 Sen15 2,622 1,361 428
PF09651 Cas_APE2256 1,017 855 488
PF09659 Cas_Csm6 816 410 234
PF09670 Cas_Cas02710 1,914 1,600 1,078
PF09810 Exo5 2,556 1,494 644
PF09823 DUF2357 2,142 1,597 820
PF09929 DUF2161 2,715 1,573 217
PF10107 Endonuc_Holl 1,394 859 340
PF10117 McrBC 7,660 5,345 2,123
PF10356 RRG7 1,430 928 411
PF10881 DUF2726 6,764 3,700 1,704
PF10926 DUF2800 3,317 1,611 635
PF11103 DUF2887 3,233 1,658 578
PF11407 RestrictionMunI 46 42 13
PF11463 R-HINP1I 319 242 68
PF11487 RestrictionSfiI 86 76 21
PF11564 BpuJI_N 177 136 46
PF11645 PDDEXK_5 1,351 1,054 493
PF12183 NotI 636 488 140
PF12187 VirArc_Nuclease 47 30 14
PF12684 DUF3799 5,421 2,786 1,061
PF12705 PDDEXK_1 97,478 58,600 21,856
PF12784 PDDEXK_2 16,708 8,690 3,204
PF13020 NOV_C 8,841 6,100 2,775
PF13156 Mrr_cat_2 2,422 1,973 626
PF13366 PDDEXK_3 15,748 12,613 2,749
PF13588 HSDR_N_2 11,880 8,016 2,075
PF13635 DUF4143 44,037 29,765 6,373
PF14082 SduA_C 2,427 1,934 1,049
PF14281 PDDEXK_4 3,630 2,870 1,942
PF14390 DUF4420 2,378 1,888 973
PF14511 RE_EcoO109I 1,088 852 221
PF14562 Endonuc_BglI 47 35 20
PF15514 ThaI 318 219 54
PF15515 MvaI_BcnI 1,390 1,072 361
PF15516 BpuSI_N 28 28 15
PF15517 TBPIP_N 70 35 2
PF15518 L_protein_N 2,053 314 86
PF15646 Tox-REase-2 161 133 64
PF15647 Tox-REase-3 119 90 76
PF15648 Tox-REase-5 1,200 779 288
PF15649 Tox-REase-7 571 392 284
PF15650 Tox-REase-9 139 132 119
PF17296 ArenaCapSnatch 971 174 20
PF17946 RecC_C 10,737 4,747 1,522
PF17949 PND 933 389 103
PF18451 CdiA_C 964 758 552
PF18474 DUF5614 1,326 450 191
PF18643 RE_BsaWI 865 346 117
PF18664 CdiA_C_tRNase 153 125 97
PF18740 EC042_2821 359 224 91
PF18741 MTES_1575 9,217 6,294 2,710
PF18742 DpnII-MboI 962 748 421
PF18743 AHJR-like 338 272 146
PF19225 Spo16_N 40 24 13
PF19500 DUF6035 424 278 159
PF19778 RE_endonuc 5,394 2,901 654
PF19810 DUF6293 1,571 917 341
PF20376 DUF6671 1,486 1,053 281
PF20472 PDDEXK_11 672 451 124
PF20516 PDDEXK_12 3,411 2,325 1,442
PF20796 PDDEXK_13 695 595 340
PF21111 CDI_toxin_EC869_like 497 419 311
PF21598 PvuRts1I-like_N 254 172 97
CL0237 HD_PDEase 560,911 304,732 79,720 PF00233 PDEase_I 48,240 18,587 5,351
PF01966 HD 226,944 123,184 23,734
PF05153 MIOX 5,519 2,677 534
PF07514 TraI_2 4,271 1,780 696
PF08668 HDOD 45,590 27,896 10,809
PF12252 SidE_PDE 262 162 99
PF12917 YfbR-like 7,265 2,860 448
PF13023 HD_3 17,480 9,900 2,386
PF13328 HD_4 69,791 30,827 5,524
PF13487 HD_5 92,716 64,843 24,869
PF13735 tRNA_NucTran2_2 10,583 6,112 1,944
PF13875 DUF4202 3,243 2,082 366
PF18019 Cas3_HD 9,246 6,478 2,599
PF21447 Ppx-GppA_III 19,757 8,292 1,709
PF21697 Ppx_C 4,375 2,293 322
CL0238 PP2C 265,370 146,424 48,521 PF00481 PP2C 84,265 38,020 13,762
PF07228 SpoIIE 122,751 73,824 24,801
PF13672 PP2C_2 58,437 34,891 10,687
PF21511 SidD_cat 12 9 9
CL0239 Insulin 7,792 3,474 1,417 PF00049 Insulin 7,446 3,208 1,212
PF03488 Ins_beta 344 267 208
CL0240 PFK 223,120 109,416 21,728 PF00365 PFK 68,620 30,830 3,428
PF00781 DAGK_cat 95,076 49,639 13,061
PF01513 NAD_kinase 59,421 28,950 5,245
PF18468 Pfk_N 177 108 9
CL0241 ABC_membrane 507,653 249,609 52,799 PF00664 ABC_membrane 480,011 238,533 50,206
PF05992 SbmA_BacA 3,972 1,239 204
PF06472 ABC_membrane_2 22,711 9,433 2,277
PF13748 ABC_membrane_3 956 414 137
CL0242 DNA_primase_lrg 7,698 4,141 1,488 PF03041 Baculo_LEF-2 193 90 32
PF04104 DNA_primase_lrg 7,503 4,051 1,456
CL0243 AEP 35,217 19,827 3,599 PF01896 DNA_primase_S 7,973 4,408 1,211
PF03090 Replicase 2,026 903 358
PF18188 PPL4 85 78 62
PF21686 LigD_Prim-Pol 25,129 14,439 1,973
CL0244 PGBD 129,852 74,996 25,727 PF01471 PG_binding_1 122,365 70,820 24,673
PF08823 PG_binding_2 1,429 945 127
PF09374 PG_binding_3 6,036 3,222 933
PF21398 PG_binding_5 81 43 23
CL0245 EDD 112,473 51,521 10,563 PF02645 DegV 39,357 20,904 5,125
PF02733 Dak1 24,494 10,014 1,327
PF03610 EIIA-man 35,674 13,986 3,080
PF13684 FakA-like_C 13,076 6,659 1,043
CL0247 2H 63,770 39,487 14,436 PF02834 LigT_PEase 9,059 6,455 3,390
PF05213 Corona_NS2A 293 55 28
PF05881 CNPase 1,115 353 141
PF06299 DUF1045 3,680 2,164 491
PF07823 CPDase 1,525 1,093 525
PF08975 2H-phosphodiest 1,457 782 256
PF09749 HVSL 3,662 2,089 866
PF10469 AKAP7_NLS 6,839 3,644 1,586
PF13563 2_5_RNA_ligase2 36,139 23,229 8,174
CL0248 ParBc 141,783 80,856 24,792 PF02195 ParBc 103,993 55,356 15,616
PF03235 DUF262 33,009 22,991 8,305
PF08857 ParBc_2 2,568 1,148 292
PF18763 ddrB-ParB 1,436 933 386
PF20188 DUF6551 773 431 203
CL0249 Phage_tail_L 6,200 1,863 645 PF05100 Phage_tail_L 4,744 1,196 363
PF08875 DUF1833 1,454 667 283
CL0250 GAD 50,102 20,672 1,945 PF02938 GAD 46,785 18,825 1,281
PF08887 GAD-like 2,261 1,083 363
PF14544 DUF4443 1,053 764 301
CL0251 MORN 63,774 38,013 19,609 PF02493 MORN 45,544 25,193 12,202
PF07661 MORN_2 18,345 12,919 7,496
CL0254 THDP-binding 693,940 325,761 38,060 PF00456 Transketolase_N 105,501 45,922 3,849
PF00676 E1_dh 118,578 54,917 6,263
PF01855 POR_N 67,535 37,956 3,547
PF02775 TPP_enzyme_C 253,002 119,122 13,582
PF02776 TPP_enzyme_N 183,901 80,845 9,873
PF02779 Transket_pyr 236,936 103,334 8,391
PF03894 XFP 14,080 6,160 306
PF09364 XFP_N 14,293 6,409 437
PF13292 DXP_synthase_N 44,534 19,603 1,781
PF17831 PDH_E1_M 23,657 8,101 415
CL0255 ATP_synthase 188,975 89,431 24,588 PF00213 OSCP 48,143 25,466 6,962
PF00430 ATP-synt_B 66,892 28,291 6,588
PF00895 ATP-synt_8 22,400 9,556 736
PF01991 vATP-synt_E 11,813 6,307 2,433
PF02108 FliH 18,834 10,492 4,557
PF02326 YMF19 2,342 810 364
PF03179 V-ATPase_G 5,558 2,459 786
PF05405 Mt_ATP-synt_B 5,270 2,097 622
PF05933 Fun_ATP-synt_8 931 374 68
PF06188 HrpE 771 386 158
PF06635 T3SS_SCTL 804 295 115
PF09811 Yae1_N 6,019 3,419 1,298
PF16999 V-ATPase_G_2 864 576 318
CL0257 Acetyltrans 1,420,406 801,137 215,874 PF00583 Acetyltransf_1 705,225 406,409 114,811
PF00765 Autoind_synth 6,837 3,404 844
PF01233 NMT 6,157 2,434 599
PF01853 MOZ_SAS 15,563 6,910 2,050
PF02100 ODC_AZ 3,414 1,786 545
PF02388 FemAB 12,124 6,351 2,114
PF02474 NodA 4,171 476 102
PF02794 HlyC 1,651 944 455
PF02799 NMT_C 6,121 2,378 562
PF03588 Leu_Phe_trans 22,213 12,791 1,476
PF04339 FemAB_like 14,541 7,935 1,327
PF04376 ATE_N 16,732 7,945 1,268
PF04377 ATE_C 18,085 8,741 1,597
PF04768 NAT 4,590 2,205 429
PF04958 AstA 9,729 2,995 477
PF05292 MCD 6,236 3,414 743
PF05301 Acetyltransf_16 2,413 1,273 562
PF06557 DUF1122 275 207 119
PF06852 DUF1248 166 123 56
PF07395 Mig-14 1,982 357 91
PF08214 HAT_KAT11 9,071 4,889 1,297
PF08444 Gly_acyl_tr_C 1,473 766 172
PF08445 FR47 11,787 7,783 2,778
PF09390 DUF1999 99 68 10
PF09924 LPG_synthase_C 22,935 10,926 3,278
PF11090 Phage_T7_Gp13 519 165 90
PF11124 Pho86 149 102 46
PF12261 T_hemolysin 2,341 1,243 468
PF12568 PanZ 2,180 630 99
PF12746 GNAT_acetyltran 5,009 3,031 1,298
PF13302 Acetyltransf_3 220,789 130,452 33,439
PF13420 Acetyltransf_4 12,822 7,394 1,943
PF13444 Acetyltransf_5 20,082 10,455 2,035
PF13480 Acetyltransf_6 34,400 23,992 10,565
PF13508 Acetyltransf_7 79,555 47,455 18,444
PF13523 Acetyltransf_8 15,716 7,422 1,410
PF13527 Acetyltransf_9 29,482 18,561 6,780
PF13673 Acetyltransf_10 76,705 42,863 13,762
PF13718 GNAT_acetyltr_2 9,378 4,007 1,070
PF13880 Acetyltransf_13 3,956 2,162 844
PF14542 Acetyltransf_CG 24,754 13,496 3,081
PF16092 CFAP61_N 1,639 882 374
PF17013 Acetyltransf_15 33 27 22
PF17668 Acetyltransf_17 11,224 6,629 1,605
PF18014 Acetyltransf_18 10,640 5,714 1,428
PF18015 Acetyltransf_19 383 286 128
PF18164 GNAT_C 1,879 1,361 580
PF18407 GNAT_like 2,500 1,189 84
PF18467 DUF5613 450 239 71
PF18713 DUF5645 233 157 81
CL0258 DALR 350,328 170,110 20,281 PF05746 DALR_1 82,643 40,332 5,795
PF08264 Anticodon_1 178,796 88,131 10,586
PF09190 DALR_2 42,807 20,849 1,919
PF19303 Anticodon_3 46,081 21,008 2,333
CL0259 OstA 56,228 31,860 11,298 PF03968 LptD_N 29,460 15,837 5,559
PF06835 LptC 22,841 13,509 5,184
PF13100 OstA_2 5,122 3,482 1,172
CL0260 NTP_transf 591,492 324,686 90,875 PF01743 PolyA_pol 68,057 36,889 8,178
PF01909 NTP_transf_2 80,621 50,210 17,603
PF02410 RsfS 43,141 22,216 4,322
PF03281 Mab-21 7,253 2,954 1,346
PF03296 Pox_polyA_pol 166 43 13
PF03445 DUF294 14,238 8,394 2,089
PF03710 GlnE 24,460 12,646 2,789
PF03813 Nrap 3,696 1,847 540
PF04229 GrpB 14,193 9,029 2,617
PF04439 Adenyl_transf 4,018 2,256 797
PF04607 RelA_SpoT 73,696 31,415 5,730
PF04991 LicD 13,700 7,658 4,016
PF06042 NTP_transf_6 6,114 3,290 649
PF07528 DZF_N 7,630 2,569 559
PF07733 DNA_pol3_alpha 81,159 40,633 6,209
PF07984 NTP_transf_7 4,428 1,137 297
PF08843 AbiEii 35,049 24,269 8,867
PF09139 Tam41_Mmp37 4,234 2,031 679
PF09970 DUF2204 1,642 1,278 621
PF10127 RlaP 10,180 5,595 1,381
PF10620 MdcG 3,473 1,713 418
PF10706 Aminoglyc_resit 2,072 1,048 364
PF12281 NTP_transf_8 2,510 1,708 631
PF12633 Adenyl_cycl_N 4,384 1,259 394
PF14091 DUF4269 1,552 1,012 317
PF14540 NTF-like 1,095 557 75
PF14792 DNA_pol_B_palm 9,032 4,782 1,493
PF14907 NTP_transf_5 12,450 9,024 5,434
PF17405 Nrap_D4 3,956 2,033 653
PF18144 SMODS 4,138 2,690 897
PF18765 Polbeta 31,270 23,237 10,373
PF19088 TUTase 4,425 1,921 616
PF19502 DUF6036 5,237 4,023 1,569
PF20697 NTase-conflict 29 29 21
PF20750 PAP_NTPase 9,218 4,181 1,238
PF21297 MID51-like_C 1,647 340 64
PF21418 LinB-like_C 456 203 46
PF21649 APMV_polyA_pol_cat_2nd 61 36 26
PF21654 DncV-like_NTFase 1,863 1,314 429
PF21655 L544_NTransf 33 11 5
CL0261 NUDIX 508,011 274,699 61,311 PF00293 NUDIX 453,745 247,298 56,609
PF03559 Hexose_dehydrat 1,654 1,113 237
PF09296 NUDIX-like 15,484 7,705 1,208
PF11788 MRP-L46 2,875 1,527 416
PF13869 NUDIX_2 4,219 1,460 413
PF14815 NUDIX_4 40,992 21,968 3,584
PF15916 DUF4743 4,308 2,388 621
PF16262 DUF4916 2,560 772 52
PF16705 NUDIX_5 1,212 203 50
PF18290 Nudix_hydro 4,230 2,133 712
CL0262 Trigger_C 103,006 56,388 18,590 PF05698 Trigger_C 44,308 21,545 5,726
PF09312 SurA_N 15,605 7,881 2,226
PF13623 SurA_N_2 6,598 4,441 1,718
PF13624 SurA_N_3 36,501 22,637 9,447
CL0263 His-Me_finger 258,042 146,536 58,432 PF01223 Endonuclease_NS 26,063 13,611 4,327
PF01844 HNH 74,561 45,966 18,660
PF02945 Endonuclease_7 5,058 2,809 1,664
PF03165 MH1 20,936 5,793 1,127
PF04231 Endonuclease_1 13,318 7,291 2,356
PF05315 ICEA 430 211 68
PF05551 zf-His_Me_endon 448 371 314
PF05766 NinG 3,605 1,204 422
PF06147 DUF968 2,800 431 124
PF07510 DUF1524 24,991 15,259 4,511
PF09230 DFF40 1,236 583 158
PF12639 Colicin-DNase 1,111 792 542
PF13391 HNH_2 20,446 14,864 7,028
PF13392 HNH_3 18,182 11,235 7,763
PF13395 HNH_4 6,134 4,382 1,641
PF13930 Endonuclea_NS_2 6,399 3,789 1,848
PF14279 HNH_5 19,061 10,798 3,102
PF14410 GH-E 783 612 468
PF14411 LHH 956 749 535
PF14412 AHH 3,179 2,410 1,391
PF14414 WHH 2,655 1,308 732
PF16784 HNHc_6 1,144 546 186
PF16786 RecA_dep_nuc 786 392 153
PF18275 His_Me_b4a2 97 51 11
PF21368 AI2M-like_HNH 2,384 938 289
PF21431 Col-Pyo_DNase 1,347 721 334
PF21586 DraIII 23 19 5
CL0264 SGNH_hydrolase 314,772 189,547 66,125 PF00657 Lipase_GDSL 63,437 34,710 12,278
PF03629 SASA 24,152 16,035 5,913
PF03996 Hema_esterase 1,117 59 26
PF04311 DUF459 1,305 706 323
PF04914 DltD 3,593 1,007 341
PF07611 DUF1574 1,068 458 228
PF08885 GSCFA 5,367 3,924 1,256
PF13472 Lipase_GDSL_2 158,741 99,497 32,652
PF13839 PC-Esterase 20,851 10,710 3,155
PF14286 DHHW 3,048 1,968 960
PF14606 Lipase_GDSL_3 3,804 2,607 798
PF16227 DUF4886 2,389 1,806 865
PF16255 Lipase_GDSL_lke 327 157 78
PF16822 ALGX 8,146 4,743 2,780
PF17182 OSK 241 149 91
PF19040 SGNH 17,504 11,416 5,430
PF21211 FkbH_N 1,131 878 310
CL0265 HIT 153,568 80,411 14,150 PF01087 GalP_UDP_transf 24,697 12,135 1,570
PF01230 HIT 93,744 51,472 7,703
PF02509 Rota_NS35_C 2,812 73 19
PF02611 CDH 3,340 934 256
PF02744 GalP_UDP_tr_C 22,331 10,612 1,136
PF04677 CwfJ_C_1 7,646 3,845 1,198
PF09830 ATP_transf 3,503 2,225 609
PF11969 DcpS_C 12,593 7,249 2,336
PF16268 DUF4921 1,601 1,043 263
PF16269 DUF4922 1,464 827 316
PF16285 DUF4931_N 1,460 587 174
PF19327 Ap4A_phos_N 3,542 2,264 638
PF20956 DUF4931_C 1,207 385 68
PF21063 Reovirus_L2_GTase 289 43 22
CL0266 PH 867,385 356,302 85,223 PF00169 PH 307,473 119,907 25,384
PF00568 WH1 17,063 6,010 1,653
PF00638 Ran_BP1 15,576 7,836 2,660
PF00640 PID 43,929 15,637 3,339
PF02174 IRS 13,334 5,502 1,443
PF02392 Ycf4 14,756 1,526 230
PF02893 GRAM 40,181 16,031 3,816
PF03517 Voldacs 4,147 2,094 738
PF03525 Meiotic_rec114 722 537 306
PF03531 SSrecog 4,371 1,736 400
PF03703 bPH_2 40,167 25,103 8,241
PF04683 Rpn13_ADRM1_Pru 5,300 1,999 589
PF06017 Myosin_TH1 15,137 5,469 852
PF06058 DCP1 5,396 2,477 912
PF06115 DUF956 1,955 596 81
PF06173 DUF986 1,698 289 45
PF06565 DM10_dom 4,460 2,110 858
PF06713 bPH_4 3,357 1,836 974
PF06979 TMEM70 3,911 2,237 843
PF07289 BBL5 1,917 733 259
PF07933 DUF1681 5,234 2,348 604
PF08000 bPH_1 6,983 2,817 402
PF08416 PTB 11,428 4,646 867
PF08458 PH_2 2,663 1,084 264
PF08512 Rttp106-like_middle 10,033 4,236 1,091
PF08567 PH_TFIIH 3,362 1,382 382
PF08644 SPT16 4,190 1,659 398
PF09380 FERM_C 50,017 18,876 3,305
PF10003 DUF2244 5,937 3,429 935
PF10480 ICAP-1_inte_bdg 1,130 294 91
PF10739 DUF2550 3,844 1,522 293
PF10756 bPH_6 9,314 5,674 1,415
PF10882 bPH_5 2,751 1,930 1,136
PF11292 DUF3093 4,676 2,491 432
PF11462 DUF3203 647 209 22
PF11531 CARM1 1,707 661 86
PF11605 Vps36_ESCRT-II 3,725 1,438 349
PF11869 DUF3389 429 167 27
PF12068 PH_RBD 7,533 2,847 517
PF12456 hSac2 4,822 1,923 520
PF12634 Inp1 1,017 573 227
PF12814 Mcp5_PH 2,783 1,538 543
PF14317 YcxB 7,289 4,786 2,786
PF14470 bPH_3 3,892 2,027 890
PF14593 PH_3 3,275 1,065 328
PF14719 PID_2 3,375 1,041 343
PF14844 PH_BEACH 15,565 8,291 1,737
PF15165 REC114-like 902 452 135
PF15169 Cybc1_Eros 1,062 357 94
PF15277 Sec3-PIP2_bind 6,222 2,534 513
PF15404 PH_4 1,033 663 251
PF15405 PH_5 3,669 1,916 479
PF15406 PH_6 993 491 109
PF15409 PH_8 7,259 2,307 431
PF15410 PH_9 15,803 6,501 1,562
PF15411 PH_10 3,184 1,541 381
PF15413 PH_11 2,662 969 218
PF16453 IQ_SEC7_PH 6,214 2,350 473
PF16457 PH_12 16,258 5,571 1,044
PF16652 PH_13 4,736 2,523 485
PF16674 UCH_N 1,284 317 48
PF16696 ZFYVE21_C 1,220 367 94
PF16726 OCRL_clath_bd 1,156 308 30
PF16764 Sharpin_PH 662 318 62
PF16776 INPP5B_PH 1,122 489 106
PF16979 SIN1_PH 3,260 1,169 375
PF17255 EbsA 1,072 404 152
PF17292 POB3_N 4,287 1,725 406
PF17339 PH_15 72 53 36
PF17353 DUF5381 236 126 52
PF17416 Glycoprot_B_PH1 1,899 190 68
PF17417 Glycoprot_B_PH2 1,775 177 58
PF17684 SCAB-PH 1,056 357 67
PF17747 VID27_PH 1,526 723 158
PF17748 VID27_N 1,519 713 152
PF17787 PH_14 6,885 2,998 423
PF17838 PH_16 12,506 5,060 912
PF17887 Jak1_Phl 5,350 1,892 149
PF17888 Carm_PH 3,323 1,509 267
PF18012 PH_17 2,693 938 239
PF18045 ISP3_C 90 36 18
PF18116 SNX17_FERM_C 2,177 638 187
PF18161 ISP1_C 196 64 39
PF18469 PH_18 200 137 45
PF18584 SYCP2_SLD 972 560 210
PF18629 DUF5629 1,027 333 25
PF18923 DUF5673 279 160 120
PF19039 ASK_PH 3,928 1,668 185
PF19057 PH_19 9,221 4,117 615
PF20399 PH_20 2,937 1,543 424
PF20794 bPH_7 151 105 53
PF21003 NucS_N 7,270 2,412 261
PF21098 PH-GRAM_MTMR6-like 5,904 1,919 357
PF21103 PH1_SSRP1-like 4,523 1,850 467
PF21242 ECT2_PH 2,376 787 216
PF21477 FERM_C_FAK1 7,707 3,432 358
PF21679 VPS13_C 7,736 3,985 1,025
PF21792 DAB2_SBM 3,270 811 118
CL0267 S11_L18p 157,927 57,977 9,669 PF00411 Ribosomal_S11 66,380 15,195 1,910
PF00861 Ribosomal_L18p 45,561 19,089 1,307
PF03463 eRF1_1 15,089 6,008 1,310
PF03464 eRF1_2 13,545 5,169 1,074
PF10116 Host_attach 3,319 2,280 981
PF17144 Ribosomal_L5e 9,474 4,021 825
PF18826 bVLRF1 3,630 2,103 699
PF18844 baeRF_family2 2,269 1,338 281
PF18845 baeRF_family3 2,591 1,610 583
PF18846 baeRF_family5 443 288 63
PF18848 baeRF_family6 574 248 90
PF18849 baeRF_family7 818 669 330
PF18851 baeRF_family8 143 91 30
PF18854 baeRF_family10 1,780 1,386 579
PF18855 baeRF_family11 469 331 71
PF18856 baeRF_family12 2,683 1,512 277
PF18859 acVLRF1 1,954 1,352 210
CL0268 Pec_lyase-like 407,528 251,916 113,995 PF00295 Glyco_hydro_28 48,257 25,028 6,881
PF00544 Pectate_lyase_4 20,900 9,720 2,026
PF01095 Pectinesterase 34,055 18,348 5,372
PF01696 Adeno_E1B_55K 518 118 58
PF02415 Chlam_PMP 6,165 5,000 4,160
PF02691 VacA 2,323 607 93
PF03211 Pectate_lyase 6,553 2,830 704
PF03212 Pertactin 4,066 1,707 714
PF03718 Glyco_hydro_49 378 192 53
PF03775 MinC_C 16,147 7,077 1,434
PF03961 FapA 7,218 4,742 2,349
PF04519 Bactofilin 28,087 18,423 6,230
PF05048 NosD 19,537 14,289 8,577
PF05594 Fil_haemagg 3,645 2,834 1,601
PF05860 TPS 19,747 15,288 8,294
PF07602 DUF1565 5,617 4,006 2,247
PF08480 Disaggr_assoc 811 525 338
PF09251 PhageP22-tail 750 69 35
PF09922 LiaF-like_C 10,463 6,263 2,334
PF10988 DUF2807 19,072 13,952 5,836
PF12218 End_N_terminal 87 35 25
PF12541 DUF3737 2,082 1,048 154
PF12708 Pectate_lyase_3 24,240 15,643 6,596
PF12951 PATR 19,573 11,395 7,383
PF13229 Beta_helix 74,217 53,618 32,518
PF13332 Fil_haemagg_2 7,466 5,798 3,321
PF13349 DUF4097 28,430 18,339 8,357
PF14262 Cthe_2159 4,033 2,721 1,303
PF14592 Chondroitinas_B 3,216 2,207 816
PF16168 AIDA 1,891 524 305
PF16315 DUF4955 465 274 121
PF16318 DUF4957 1,014 685 264
PF17115 Toast_rack_N 830 677 375
PF17161 DUF5123 1,099 647 286
PF18781 Phage_spike_2 6 4 3
PF18783 IPU_b_solenoid 383 195 53
PF18835 Beta_helix_2 128 85 16
PF18836 B_solenoid_ydck 1,874 578 262
PF18841 B_solenoid_dext 340 172 44
PF18883 AC_1 10,386 4,433 1,822
PF18886 DUF5649 754 662 568
PF18889 Beta_helix_3 506 430 352
PF20585 Pectate_lyase_5 1,651 900 667
PF21562 Gp63_3rd_G7C 18 10 7
CL0269 Maf 120,469 65,754 10,870 PF01725 Ham1p_like 53,449 29,083 4,331
PF01931 NTPase_I-T 7,374 3,618 955
PF02545 Maf 59,521 32,986 5,576
PF11576 HcgB 121 67 8
CL0270 Iso_DH 268,225 113,568 11,743 PF00180 Iso_dh 129,382 49,783 4,352
PF01515 PTA_PTB 56,257 23,049 2,526
PF02504 FA_synthesis 33,812 16,642 2,212
PF03971 IDH 14,455 5,810 433
PF04166 PdxA 34,316 18,286 2,221
CL0271 F-box 297,411 166,891 82,480 PF00646 F-box 124,428 78,221 42,595
PF06881 Elongin_A 3,831 2,118 844
PF09372 PRANC 1,452 435 261
PF12937 F-box-like 161,375 84,888 41,836
PF13013 F-box-like_2 301 258 228
PF15966 F-box_4 2,390 796 219
PF18511 F-box_5 3,931 1,671 386
CL0272 RGS 62,394 23,438 6,319 PF00615 RGS 56,701 21,168 5,894
PF09128 RGS-like 5,691 2,271 425
CL0273 CYTH 57,929 32,825 9,777 PF01928 CYTH 36,538 20,749 5,441
PF02940 mRNA_triPase 2,101 1,232 504
PF08612 Med20 2,801 1,315 495
PF09359 VTC 12,151 7,612 2,629
PF09637 Med18 2,671 1,189 430
PF09817 Zwilch 1,471 687 273
PF10640 MCEL_TPase 189 41 5
CL0274 WRKY-GCM1 78,279 44,779 20,915 PF03101 FAR1 17,053 10,265 5,084
PF03106 WRKY 32,130 15,404 5,118
PF03108 DBD_Tnp_Mut 9,946 6,978 3,964
PF03615 GCM 1,834 819 233
PF04500 FLYWCH 10,127 6,701 4,292
PF08731 AFT 844 646 423
PF09729 Gti1_Pac2 4,706 3,017 1,251
PF20783 DUF5575_N 347 172 53
PF21599 ZSWIM3_N 1,290 788 521
CL0276 Nucleot_cyclase 773,836 449,735 183,367 PF00211 Guanylate_cyc 154,947 94,076 35,926
PF00563 EAL 266,416 143,534 55,629
PF00990 GGDEF 490,335 288,780 120,559
PF05165 GCH_III 1,129 489 109
PF06327 Adcy_cons_dom 8,365 3,496 515
PF10851 DUF2652 1,463 1,025 374
PF12469 Cmr2_N 2,045 1,632 887
PF17853 GGDEF_2 47,334 24,723 7,815
PF18182 mCpol 529 450 295
CL0277 FAD-oxidase_C 185,312 96,075 17,243 PF02913 FAD-oxidase_C 112,410 57,060 8,265
PF04030 ALO 19,318 9,898 1,974
PF08031 BBE 41,594 24,104 5,927
PF09129 Chol_subst-bind 745 352 83
PF09265 Cytokin-bind 4,289 2,232 490
PF09330 Lact-deh-memb 4,284 1,281 154
PF18371 FAD_SOX 2,572 1,090 347
PF18690 DUF5639 92 59 6
CL0278 AIG2 47,926 26,404 8,034 PF04752 ChaC 15,179 7,477 1,588
PF06094 GGACT 24,748 15,192 5,359
PF13772 AIG2_2 8,348 4,006 1,329
CL0279 GatB_YqeY 82,792 40,253 5,286 PF02637 GatB_Yqey 46,983 21,506 2,694
PF04558 tRNA_synt_1c_R1 3,115 1,354 252
PF09424 YqeY 32,691 17,394 2,341
CL0280 PIN 437,900 261,801 71,533 PF00752 XPG_N 21,688 11,799 3,634
PF01850 PIN 142,276 99,981 27,429
PF01927 Mut7-C 9,322 5,956 1,872
PF01936 NYN 48,245 26,356 6,840
PF02639 DUF188 16,028 7,244 655
PF02739 5_3_exonuc_N 63,410 31,008 4,872
PF03159 XRN_N 11,208 5,935 1,868
PF04900 Fcf1 7,645 3,401 924
PF05991 NYN_YacP 12,932 7,028 2,032
PF07000 DUF1308 2,545 1,091 425
PF08745 PIN_5 905 420 73
PF10130 PIN_2 2,051 1,679 864
PF11977 RNase_Zc3h12a 8,134 3,471 1,300
PF13470 PIN_3 23,044 16,763 5,495
PF13638 PIN_4 28,759 12,372 2,991
PF14367 DUF4411 2,796 2,101 858
PF14626 RNase_Zc3h12a_2 72 49 38
PF16289 PIN_12 2,307 1,801 1,151
PF16953 PRORP 3,087 1,600 633
PF17146 PIN_6 6,199 3,440 978
PF18475 PIN7 1,437 884 431
PF18476 PIN_8 1,361 1,125 841
PF18477 PIN_9 2,941 1,870 631
PF18478 PIN_10 1,448 1,101 506
PF18479 PIN_11 933 292 68
PF18480 DUF5615 14,937 11,419 3,581
PF18481 DUF5616 1,552 1,123 387
PF20698 PIN-TPR-GreABC 596 516 378
PF21484 Chp1-like_PIN 13 8 7
CL0281 CCT 21,660 9,467 3,168 PF06203 CCT 16,427 6,956 2,223
PF09425 Jas_motif 5,231 2,512 949
CL0282 Serum_albumin 2,787 1,000 216 PF00273 Serum_albumin 2,778 995 211
PF09164 VitD-bind_III 618 221 28
CL0283 LigB 53,522 29,981 6,311 PF01875 Memo 16,645 11,554 3,677
PF02900 LigB 36,875 18,427 2,634
CL0284 Allatostatin 212 119 65 PF05953 Allatostatin 211 119 65
PF08261 Carcinustatin 5 6 5
CL0285 YycI_YycH 5,864 2,877 1,133 PF07435 YycH 2,814 1,378 598
PF09648 YycI 3,050 1,501 537
CL0286 GCS 268,565 106,902 15,808 PF00120 Gln-synt_C 121,411 42,474 4,604
PF00217 ATP-gua_Ptrans 24,536 7,611 1,722
PF02934 GatB_N 50,064 23,063 2,844
PF03074 GCS 4,729 2,067 577
PF03136 Pup_ligase 12,353 3,786 688
PF04107 GCS2 31,615 16,442 2,333
PF04262 Glu_cys_ligase 10,356 3,895 647
PF09899 DUF2126 6,962 3,474 403
PF11765 Hyphal_reg_CWP 688 542 385
PF12224 Amidoligase_2 5,841 3,549 1,606
CL0287 Transthyretin 577,563 351,509 129,489 PF00576 Transthyretin 19,723 9,219 1,148
PF00775 Dioxygenase_C 40,738 19,250 2,597
PF01060 TTR-52 4,676 3,427 1,547
PF01190 Pollen_Ole_e_1 8,407 4,271 1,419
PF01847 VHL 2,551 1,688 843
PF03714 PUD 5,140 2,409 673
PF05738 Cna_B 4,904 3,339 2,448
PF06321 P_gingi_FimA 2,003 812 494
PF07210 DUF1416 2,988 707 88
PF08308 PEGA 22,219 17,551 11,428
PF08400 phage_tail_N 3,210 908 432
PF08842 Mfa2 3,562 1,337 712
PF09430 EMC7_beta-sandw 4,608 1,955 674
PF10670 DUF4198 9,689 5,682 1,558
PF10794 DUF2606 152 33 15
PF11008 DUF2846 2,508 1,470 610
PF11182 AlgF 1,569 428 143
PF12790 T6SS-SciN 7,916 3,171 946
PF12866 DUF3823 1,304 764 222
PF12892 FctA 2,780 1,711 1,146
PF12985 DUF3869 186 43 25
PF13149 Mfa_like_1 8,816 3,821 2,169
PF13598 DUF4139 11,096 8,003 3,142
PF13620 CarboxypepD_reg 117,636 87,398 42,033
PF13715 CarbopepD_reg_2 201,614 129,197 33,093
PF13953 PapC_C 26,332 6,223 1,677
PF14344 DUF4397 8,000 5,648 2,579
PF14660 DUF4458 242 84 24
PF14686 fn3_3 7,125 3,759 1,022
PF15415 Mfa_like_2 74 24 18
PF15495 Fimbrillin_C 1,511 681 413
PF15976 CooC_C 2,091 675 265
PF16249 DUF4906 567 287 191
PF16371 MetallophosN 3,490 2,019 553
PF16555 GramPos_pilinD1 3,014 1,561 840
PF16570 GramPos_pilinD3 181 123 44
PF17145 DUF5119 1,222 408 209
PF17210 SdrD_B 13,177 10,538 7,789
PF17224 DUF5300 22 5 5
PF17802 SpaA 23,766 12,454 7,673
PF18002 T6_Ig_like 58 38 20
PF18067 Lipase_C 752 491 107
PF19403 SpaA_2 1,073 893 686
PF19407 DUF5979 2,581 1,881 1,270
PF20200 DUF6562 636 359 236
PF20598 DUF6795 598 431 235
PF20608 Phage_tube_C 339 60 27
PF20674 SpaA_3 887 720 467
PF21489 Fim1C-like_C 75 23 10
PF21514 FimA-like_C 81 33 14
PF21768 AF_1763-like_C 249 199 66
CL0288 DAP_epimerase 116,671 60,482 9,100 PF01678 DAP_epimerase 43,072 23,240 3,306
PF02567 PhzC-PhzF 40,819 22,561 3,957
PF04303 PrpF 14,129 6,651 852
PF05544 Pro_racemase 18,647 8,030 985
CL0289 FBD 155,568 79,595 13,192 PF01571 GCV_T 109,126 55,384 8,793
PF04268 SoxG 7,415 4,042 1,038
PF10396 TrmE_N 39,097 20,242 3,433
CL0290 EPT_RTPC 120,147 56,006 8,720 PF00275 EPSP_synthase 107,490 49,248 6,802
PF01137 RTC 12,655 6,758 1,918
CL0291 KNTase_C 152,144 97,417 34,958 PF01934 HepT-like 25,570 19,032 6,726
PF05168 HEPN 24,509 18,133 7,550
PF05942 PaREP1 2,302 1,645 636
PF07827 KNTase_C 340 178 79
PF08335 GlnD_UR_UTase 45,081 21,825 4,165
PF08780 NTase_sub_bind 5,594 3,989 1,207
PF10335 DUF294_C 12,339 6,864 1,454
PF12358 DUF3644 1,377 1,049 358
PF13643 DUF4145 7,895 5,804 2,494
PF17419 MauJ 325 288 201
PF18280 Ant-IIb_sub-bd 80 48 14
PF18498 DUF5618 351 293 74
PF18725 HEPN_SAV2148 1,027 113 8
PF18726 HEPN_SAV_6107 2,800 1,477 320
PF18728 HEPN_AbiV 806 675 456
PF18729 HEPN_STY4199 952 119 38
PF18730 HEPN_Cthe2314 664 459 235
PF18731 HEPN_Swt1 2,273 1,757 608
PF18732 HEPN_AbiA_CTD 50 35 22
PF18733 HEPN_LA2681 641 480 275
PF18734 HEPN_AbiU2 1,164 955 734
PF18735 HEPN_RiboL-PSP 2,487 1,971 1,199
PF18736 pEK499_p136 235 182 130
PF18737 HEPN_MAE_28990 1,082 832 453
PF18738 HEPN_DZIP3 2,890 2,245 1,410
PF18739 HEPN_Apea 1,588 1,252 902
PF18867 HEPN-like_int 6 7 7
PF18869 HEPN_RnaseLS 25 17 13
PF18915 DUF5667 5,550 4,056 2,433
PF19034 RnlA-toxin_DBD 301 204 131
PF20797 HepT-like_2 1,675 1,341 615
PF21693 SWT1_3rd 137 101 60
CL0292 LysE 644,435 321,443 62,205 PF01169 UPF0016 19,710 9,879 1,908
PF01810 LysE 131,528 57,367 9,473
PF01914 MarC 31,389 13,682 2,294
PF01925 TauE 148,994 79,950 15,871
PF02659 Mntp 15,854 8,162 1,740
PF02673 BacA 48,968 24,661 3,878
PF02674 Colicin_V 35,619 19,086 6,499
PF02683 DsbD 61,382 33,641 6,688
PF03239 FTR1 18,793 8,745 1,639
PF03596 Cad 4,799 1,819 384
PF03741 TerC 57,024 25,142 2,417
PF03824 NicO 18,401 8,189 1,855
PF04332 DUF475 5,714 2,357 173
PF04955 HupE_UreJ 7,420 4,081 1,085
PF11139 SfLAP 6,046 3,688 975
PF13386 DsbD_2 18,673 11,613 3,075
PF13795 HupE_UreJ_2 12,545 8,586 2,154
PF16955 OFeT_1 531 283 65
PF19510 DUF6044 1,084 607 246
CL0293 CDC 43,055 20,320 6,879 PF00314 Thaumatin 14,325 7,861 2,271
PF01289 Thiol_cytolysin 2,163 833 444
PF01823 MACPF 19,918 8,407 2,879
PF03347 TDH 152 24 11
PF04598 Gasdermin 3,206 1,202 402
PF06355 Aegerolysin 796 470 232
PF06369 Anemone_cytotox 1,228 785 281
PF07367 FB_lectin 470 302 139
PF21230 Nakanori 804 445 222
CL0296 GroES 601,509 278,436 38,280 PF00166 Cpn10 61,261 22,001 2,543
PF08240 ADH_N 506,954 240,760 33,614
PF16884 ADH_N_2 33,291 15,683 2,149
CL0297 PhoU 81,619 39,339 8,159 PF01865 PhoU_div 21,432 10,320 2,327
PF01895 PhoU 60,231 29,055 5,847
CL0298 tRNA_bind_arm 138,584 61,748 5,616 PF02403 Seryl_tRNA_N 54,010 24,832 1,982
PF02912 Phe_tRNA-synt_N 42,840 17,276 1,181
PF10458 Val_tRNA-synt_C 41,731 19,640 2,453
CL0299 Peptidase_SF 192,743 101,523 27,484 PF00717 Peptidase_S24 94,613 46,732 12,548
PF10502 Peptidase_S26 95,387 53,759 14,873
PF16452 Phage_CI_C 1,727 561 133
PF18087 RuBisCo_chap_C 1,040 537 123
CL0300 TAT 31,175 15,713 5,476 PF02921 UCR_TM 3,915 1,752 319
PF10399 UCR_Fe-S_N 11,293 5,042 325
PF10518 TAT_signal 15,964 8,920 4,858
CL0301 PA14 32,837 21,316 9,435 PF07691 PA14 30,724 19,983 8,571
PF10528 GLEYA 2,132 1,352 892
CL0302 Arginase 158,812 79,388 15,320 PF00491 Arginase 75,215 36,867 6,783
PF00850 Hist_deacetyl 81,444 41,371 7,934
PF12640 UPF0489 2,150 1,150 603
CL0303 H2TH 133,163 59,702 8,891 PF00416 Ribosomal_S13 52,927 16,750 1,399
PF05833 NFACT_N 19,962 10,891 3,507
PF06831 H2TH 57,883 30,585 3,602
PF21763 DHH_CID 2,387 1,476 383
CL0304 CheY 2,077,856 1,080,012 292,720 PF00072 Response_reg 1,847,959 985,233 280,181
PF00919 UPF0004 100,616 48,647 6,217
PF01058 Oxidored_q6 81,087 28,293 2,675
PF03709 OKR_DC_1_N 11,958 1,951 186
PF06490 FleQ 3,250 1,089 127
PF09456 RcsC 1,670 203 32
PF16359 RcsD_ABL 1,671 213 40
PF16968 TadZ_N 1,028 248 68
PF19192 Response_reg_2 439 335 222
PF19864 Radical_SAM_N2 14,039 8,228 1,768
PF20161 VpsR 3,343 945 171
PF20274 cREC_REC 2,443 1,384 427
PF20299 NARF 36 33 23
PF21155 VpsT-like_REC 2,044 543 158
PF21194 TadZ-like_ARD 295 191 142
PF21332 AmiR_N 1,938 756 162
PF21695 GlnR_1st 5,167 1,648 114
PF21714 KaiA_N 507 264 46
CL0305 PTH2 17,980 9,443 2,103 PF01981 PTH2 12,947 6,958 1,720
PF09391 DUF2000 5,031 2,485 383
CL0306 HeH 121,750 53,214 15,224 PF02037 SAP 33,017 16,147 6,895
PF03020 LEM 6,589 3,062 1,009
PF07498 Rho_N 41,054 15,789 2,450
PF07766 LETM1_RBD 9,950 4,782 1,498
PF08198 Thymopoietin 1,753 638 145
PF08799 PRP4 7,320 2,934 699
PF09124 Endonuc-dimeris 535 85 37
PF10208 ARMET_C 2,021 960 292
PF11774 Lsr2 9,686 4,289 994
PF12949 HeH 2,148 1,208 485
PF18081 FANC_SAP 2,037 796 65
PF18410 BTHB 1,934 713 122
PF18953 SAP_new25 1,832 922 277
PF21169 Fan1_SAP 1,058 385 63
PF21488 YqbF_HeH 67 47 20
PF21728 PADR1_N 2,461 1,085 342
CL0307 FUSC 88,553 40,210 11,037 PF04632 FUSC 17,842 5,721 1,810
PF04982 HPP 14,062 7,782 1,939
PF06081 ArAE_1 9,664 4,368 1,048
PF10334 ArAE_2 3,189 1,853 614
PF10337 ArAE_2_N 3,517 1,918 630
PF11168 DUF2955 2,240 861 179
PF11744 ALMT 5,426 2,886 1,030
PF12805 FUSC-like 11,066 3,613 740
PF13515 FUSC_2 38,810 18,301 5,003
CL0308 DMSO_reductase 36,698 18,701 3,168 PF03916 NrfD 26,714 14,860 2,353
PF04976 DmsC 9,864 3,758 804
PF14589 NrfD_2 117 96 48
CL0310 DinB 174,363 114,215 24,365 PF04978 DUF664 20,578 12,672 1,523
PF05163 DinB 22,318 14,368 3,567
PF07606 DUF1569 3,609 2,680 804
PF07609 DUF1572 4,591 3,427 560
PF08020 DUF1706 4,389 2,331 685
PF09351 DUF1993 9,083 4,685 841
PF11716 MDMPI_N 42,377 27,635 5,157
PF12867 DinB_2 67,449 46,688 12,050
CL0311 SCP2 75,590 40,224 9,340 PF02036 SCP2 40,898 20,626 5,624
PF07398 MDMPI_C 9,097 5,254 895
PF13530 SCP2_2 11,783 7,062 1,872
PF14864 Alkyl_sulf_C 8,464 4,359 811
PF17843 MycE_N 163 129 48
PF17844 SCP_3 5,190 2,840 184
CL0312 HemS_ChuX 7,355 3,179 662 PF05171 HemS 5,001 2,178 451
PF06228 ChuX_HutX 2,706 1,196 283
CL0314 PP-binding 325,973 185,180 73,089 PF00550 PP-binding 317,360 181,505 71,893
PF07377 DUF1493 3,636 1,200 409
PF10501 Ribosomal_L50 2,131 1,172 457
PF14573 PP-binding_2 114 34 22
PF18325 Fas_alpha_ACP 2,727 1,270 316
CL0315 Gx_transp 154,580 80,447 19,716 PF01891 CbiM 16,638 8,840 1,307
PF02592 Vut_1 21,864 11,336 1,423
PF02632 BioY 22,908 12,225 2,736
PF04093 MreD 21,460 10,953 3,532
PF06177 QueT 6,056 3,147 648
PF07155 ECF-ribofla_trS 12,168 6,135 1,877
PF07456 Hpre_diP_synt_I 5,462 3,322 993
PF07694 5TM-5TMR_LYT 12,263 5,347 1,982
PF09512 ThiW 2,844 1,378 184
PF09515 Thia_YuaJ 4,661 2,519 732
PF12822 ECF_trnsprt 21,658 11,062 3,115
PF17099 TrpP 1,589 808 138
PF20221 DUF6580 4,074 2,997 1,128
PF20973 VUPS 921 450 185
CL0316 Acyl_transf_3 201,999 120,739 49,506 PF01757 Acyl_transf_3 141,216 86,522 39,719
PF04235 DUF418 16,814 9,702 2,777
PF05857 TraX 8,286 3,860 1,605
PF07779 Cas1_AcylT 4,334 1,926 645
PF07786 HGSNAT_cat 19,486 12,079 3,575
PF10129 OpgC_C 6,436 3,095 800
PF11318 DUF3120 781 404 44
PF12291 DUF3623 1,145 819 216
PF16401 DUF5009 5,516 3,634 853
CL0317 Multiheme_cytos 96,373 63,111 21,301 PF02085 Cytochrom_CIII 5,667 4,413 1,664
PF02276 CytoC_RC 2,247 1,688 549
PF02335 Cytochrom_C552 6,445 3,268 758
PF03264 Cytochrom_NNT 13,646 7,140 1,533
PF03892 NapB 4,117 1,898 399
PF09698 GSu_C4xC__C2xCH 731 651 416
PF09699 Paired_CXXCH_1 12,504 10,238 4,849
PF09719 C_GCAxxG_C_C 9,158 6,257 2,064
PF11783 Cytochrome_cB 2,082 1,645 328
PF13435 Cytochrome_C554 19,696 14,817 5,760
PF13447 Multi-haem_cyto 6,537 2,480 378
PF13695 zf-3CxxC 4,259 2,188 781
PF14522 Cytochrome_C7 10,389 8,082 2,882
PF14537 Cytochrom_c3_2 4,977 3,730 1,714
PF17180 zf-3CxxC_2 1,456 609 274
PF18978 DUF5714 1,188 835 285
CL0318 Cytochrome-c 377,957 235,641 59,196 PF00034 Cytochrom_C 157,222 96,882 25,099
PF02167 Cytochrom_C1 16,380 7,696 937
PF02433 FixO 16,564 7,398 595
PF03150 CCP_MauG 29,255 18,908 4,229
PF06537 DHOR 9,880 5,870 1,354
PF07635 PSCyt1 33,770 27,556 9,340
PF09086 DUF1924 1,366 992 158
PF09098 Dehyd-heme_bind 1,231 712 294
PF09626 DHC 2,709 1,911 685
PF10643 Cytochrome-c551 67 49 21
PF13442 Cytochrome_CBB3 118,682 72,973 20,613
PF14376 Haem_bd 5,839 3,493 867
PF14495 Cytochrom_C550 1,596 756 86
PF21342 SoxA-TsdA_cyt-c 8,614 5,191 734
PF21419 RoxA-like_Cyt-c 4,311 2,605 855
CL0319 SHS2 134,162 67,576 16,746 PF01951 Archease 10,257 6,506 2,258
PF02169 LPP20 4,379 2,478 1,135
PF02491 SHS2_FTSA 32,431 12,963 2,186
PF03876 SHS2_Rpb7-N 10,886 4,542 1,080
PF04832 SOUL 11,267 6,499 2,199
PF06445 GyrI-like 40,938 22,030 5,901
PF07311 Dodecin 12,890 6,823 597
PF14526 Cass2 10,688 5,909 1,766
PF16753 Tipalpha 427 20 8
CL0320 PepSY 106,185 55,355 20,125 PF00031 Cystatin 13,025 6,963 2,609
PF00666 Cathelicidins 1,539 918 323
PF03413 PepSY 27,758 14,221 5,767
PF04355 SmpA_OmlA 20,189 9,698 2,738
PF06907 Latexin_N 1,296 562 104
PF07430 PP1 30 18 11
PF07448 Spp-24 747 375 81
PF07467 BLIP 114 86 49
PF07504 FTP 16,913 9,042 3,117
PF09200 Monellin 1 1 1
PF11396 PepSY_like 5,670 2,996 1,370
PF11399 DUF3192 1,138 642 194
PF12978 DUF3862 759 413 254
PF13028 DUF3889 1,154 607 192
PF13670 PepSY_2 6,555 3,408 1,089
PF13995 YebF 977 161 41
PF14172 DUF4309 1,228 667 284
PF14620 YPEB_PepSY1-2 2,677 1,583 456
PF14731 Staphopain_pro 148 30 19
PF16244 DUF4901 2,259 1,447 731
PF16845 SQAPI 4,511 2,543 1,099
PF17881 DUF5590 2,718 1,078 382
PF20630 Latexin_C 1,348 587 112
CL0321 PLAT 31,468 14,771 4,991 PF01477 PLAT 29,824 13,823 4,594
PF06232 ATS3 1,369 757 246
PF10182 Flo11 273 212 179
CL0322 RND_permease 441,080 220,926 47,299 PF00873 ACR_tran 242,734 116,740 22,916
PF02355 SecD_SecF 79,849 40,672 5,683
PF02460 Patched 25,250 11,284 4,405
PF03176 MMPL 84,914 48,036 12,901
PF12349 Sterol-sensing 12,721 5,816 1,749
PF21760 SecD_1st 42,441 20,924 2,651
CL0323 Patatin 272,762 154,893 45,571 PF00698 Acyl_transf_1 127,645 75,553 21,878
PF01734 Patatin 132,314 73,230 21,915
PF01735 PLA2_B 11,737 5,459 1,338
PF16073 SAT 8,374 4,302 1,002
PF19890 DUF6363 9,956 3,806 617
CL0324 Homing_endonuc 40,076 23,879 10,421 PF00961 LAGLIDADG_1 6,725 4,654 2,397
PF03161 LAGLIDADG_2 3,082 2,330 1,176
PF05204 Hom_end 940 512 263
PF09062 Endonuc_subdom 22 14 6
PF10298 WhiA_N 11,642 3,460 454
PF14527 LAGLIDADG_WhiA 13,551 4,689 967
PF14528 LAGLIDADG_3 15,875 11,824 5,764
CL0326 Reo_sigma 2,762 393 122 PF00541 Adeno_knob 1,202 137 47
PF01664 Reo_sigma1 178 35 7
PF04582 Reo_sigmaC 869 140 22
PF08931 Caudo_bapla_RBP 202 46 22
PF16812 AdHead_fibreRBD 294 28 18
PF21583 Fiber_head_BAdV-4 11 7 6
CL0327 Pilus 86,139 53,382 18,604 PF00114 Pilin 10,707 7,292 1,744
PF01917 Arch_flagellin 5,055 3,451 953
PF02501 T2SSI 7,035 3,608 972
PF05307 Bundlin 204 117 80
PF05946 TcpA 226 73 14
PF07419 PilM 1,187 320 142
PF08334 T2SSG 19,729 11,814 3,238
PF08805 PilS 2,397 864 409
PF11530 Pilin_PilX 99 36 13
PF11612 T2SSJ 6,883 3,957 1,611
PF12019 GspH 20,735 13,676 6,741
PF16732 ComP_DUS 9,898 6,713 2,070
PF16734 Pilin_GH 1,696 1,314 580
PF18223 PilJ_C 107 60 44
PF18682 PilA4 70 58 25
PF21444 CofB_pilin_dom 115 51 20
CL0328 2heme_cytochrom 591,002 190,347 38,103 PF00033 Cytochrome_B 265,429 35,826 4,771
PF01292 Ni_hydr_CYTB 64,431 33,450 6,620
PF01578 Cytochrom_C_asm 94,996 39,705 6,456
PF01794 Ferric_reduct 56,638 28,690 7,148
PF02628 COX15-CtaA 32,975 18,953 3,762
PF03188 Cytochrom_B561 17,623 9,149 3,470
PF09990 DUF2231 15,774 10,309 2,961
PF10348 DUF2427 3,312 1,771 378
PF13631 Cytochrom_B_N_2 35,331 10,679 1,739
PF14358 DUF4405 3,774 2,903 1,452
PF20139 DUF6529 860 569 131
CL0329 S5 921,520 401,569 61,905 PF00204 DNA_gyraseB 107,222 34,446 2,923
PF00288 GHMP_kinases_N 140,013 73,182 14,655
PF00380 Ribosomal_S9 55,021 20,498 2,084
PF00475 IGPD 39,591 16,245 1,085
PF00825 Ribonuclease_P 41,358 24,258 7,719
PF01119 DNA_mis_repair 48,873 25,718 5,331
PF01138 RNase_PH 104,316 43,575 5,861
PF01205 UPF0029 31,976 16,094 3,284
PF03331 LpxC 27,311 12,137 1,906
PF03719 Ribosomal_S5_C 55,058 18,623 2,211
PF03764 EFG_IV 96,736 36,333 3,459
PF05362 Lon_C 87,644 40,369 6,391
PF08714 Fae 4,330 1,674 167
PF09108 Xol-1_N 34 27 21
PF09239 Topo-VIb_trans 4,590 2,692 503
PF10509 GalKase_gal_bdg 29,762 15,464 3,067
PF13541 ChlI 70,263 32,425 3,258
PF17942 Morc6_S5 5,939 2,614 726
CL0330 AVL9 46,708 19,908 4,426 PF02141 DENN 36,170 15,452 3,060
PF07792 Afi1 1,680 804 209
PF08616 SPA 2,895 1,198 346
PF09794 Avl9 4,944 2,202 723
PF09804 DENND11 2,708 1,169 339
CL0331 EpsM 61,775 36,340 15,011 PF03245 Phage_lysis 5,988 2,338 455
PF04350 PilO 13,914 9,133 3,851
PF04612 T2SSM 8,260 4,687 1,936
PF05137 PilN 20,678 13,166 6,039
PF10721 DUF2514 2,209 923 236
PF10741 T2SSM_b 3,876 2,559 1,315
PF12693 GspL_C 6,873 3,584 1,316
PF18222 PilN_bio_d 103 69 20
CL0333 gCrystallin 27,704 12,669 3,981 PF00030 Crystall 20,588 7,833 1,874
PF03995 Inhibitor_I36 5,427 3,856 1,785
PF08964 Crystall_3 296 193 108
PF09076 Crystall_2 405 215 84
PF09117 MiAMP1 273 175 67
PF09207 Yeast-kill-tox 6 7 6
PF15138 Syncollin 485 302 43
PF17945 Crystall_4 148 61 20
PF18258 IL4_i_Ig 92 52 35
CL0334 THBO-biosyn 169,359 79,758 10,572 PF01014 Uricase 7,282 3,312 459
PF01227 GTP_cyclohydroI 44,793 19,002 1,856
PF01242 PTPS 41,629 21,811 3,098
PF02152 FolB 40,097 19,346 3,763
PF02649 GCHY-1 11,411 5,966 704
PF14489 QueF 24,017 10,253 643
PF14819 QueF_N 8,124 2,789 249
CL0335 FumRed-TM 56,929 24,995 4,513 PF01127 Sdh_cyt 46,577 20,613 3,410
PF02300 Fumarate_red_C 2,805 991 236
PF02313 Fumarate_red_D 2,784 954 167
PF05328 CybS 3,545 1,779 516
PF07950 MCP1_TM 1,215 661 191
CL0336 FMN-binding 319,875 182,299 33,451 PF01243 Putative_PNPOx 122,744 70,137 11,314
PF01613 Flavin_Reduct 96,412 51,778 9,477
PF04075 F420H2_quin_red 26,554 16,543 3,118
PF04289 DUF447_N 2,815 1,863 437
PF04299 FMN_bind_2 15,088 9,082 1,643
PF10012 DUF2255 2,238 1,696 441
PF12766 Pyridox_oxase_2 4,670 3,035 1,006
PF12900 Pyridox_ox_2 27,504 16,617 3,611
PF13883 Pyrid_oxidase_2 10,203 5,166 1,385
PF16242 Pyrid_ox_like 11,933 6,772 1,536
CL0337 RF 129,766 58,064 6,051 PF00472 RF-1 126,209 56,246 5,484
PF10213 MRP-S28 3,555 1,818 567
CL0339 PFL-like 140,178 58,812 9,624 PF01228 Gly_radical 25,964 9,117 1,437
PF02867 Ribonuc_red_lgC 74,154 32,364 4,687
PF02901 PFL-like 26,591 10,392 2,190
PF05167 DUF711 8,329 3,424 487
PF11230 YjjI-like 2,416 544 91
PF13597 NRDD 24,835 11,151 1,871
CL0340 PTase-anion_tr 98,768 40,718 9,665 PF00359 PTS_EIIA_2 79,170 32,918 8,658
PF07565 Band_3_cyto 19,596 7,800 1,009
CL0341 LDH_C 99,854 35,117 4,449 PF02866 Ldh_1_C 77,155 25,606 3,162
PF11975 Glyco_hydro_4C 22,697 9,511 1,287
CL0342 TolB_N 106,758 56,338 17,371 PF03783 CsgG 13,493 8,293 3,570
PF03886 ABC_trans_aux 17,453 9,416 3,268
PF03923 Lipoprotein_16 4,110 1,191 434
PF04052 TolB_N 16,649 7,537 1,201
PF04390 LptE 22,534 13,230 3,569
PF05211 NLBH 1,718 94 39
PF05643 GNA1162-like 2,859 1,475 450
PF11684 DUF3280 1,673 1,057 344
PF13036 LpoB 6,978 3,366 1,035
PF13590 DUF4136 13,183 7,663 2,293
PF16539 FlgT_M 1,385 705 233
PF17680 FlgO 3,675 2,247 1,044
PF18500 CadC_C1 1,054 91 20
CL0343 MHC 139,624 31,870 4,996 PF00129 MHC_I 75,574 16,461 3,317
PF00969 MHC_II_beta 52,059 11,517 1,035
PF00993 MHC_II_alpha 8,734 2,258 354
PF11624 M157 167 48 29
PF14586 MHC_I_2 132 84 53
PF16497 MHC_I_3 2,979 1,542 254
PF21584 2L_N_poxvirus 10 7 3
CL0344 4Fe-4S 1,079,861 540,721 91,353 PF00037 Fer4 110,918 59,428 15,362
PF04060 FeS 26,586 15,614 2,661
PF04068 RLI 12,163 5,070 971
PF04879 Molybdop_Fe4S4 105,693 49,648 6,476
PF05187 ETF_QO 20,513 8,035 651
PF06902 Fer4_19 5,440 3,386 719
PF12797 Fer4_2 8,883 4,333 1,496
PF12798 Fer4_3 1,052 564 326
PF12800 Fer4_4 18,323 9,323 2,572
PF12801 Fer4_5 41,231 24,346 4,883
PF12837 Fer4_6 8,184 5,623 2,196
PF12838 Fer4_7 191,109 97,549 19,165
PF13183 Fer4_8 109,242 55,358 8,023
PF13187 Fer4_9 57,710 36,692 10,499
PF13237 Fer4_10 47,448 24,687 7,228
PF13247 Fer4_11 73,631 32,646 4,313
PF13353 Fer4_12 135,720 74,139 18,034
PF13370 Fer4_13 24,304 13,741 2,659
PF13459 Fer4_15 17,132 8,806 1,784
PF13484 Fer4_16 30,811 17,424 2,679
PF13534 Fer4_17 25,028 12,134 2,603
PF13746 Fer4_18 16,089 8,021 723
PF14691 Fer4_20 72,026 33,992 3,645
PF14697 Fer4_21 45,866 18,984 4,195
PF14710 Nitr_red_alph_N 7,306 1,666 149
PF17179 Fer4_22 7,812 5,086 1,102
PF18009 Fer4_23 716 494 86
PF18109 Fer4_24 1,360 375 38
CL0345 Aerolisin_ETX 3,033 1,719 923 PF01117 Aerolysin 1,173 504 241
PF03318 ETX_MTX2 1,748 1,130 656
PF18063 BB_PF 110 98 71
CL0346 Ribo_L29 52,278 22,236 4,217 PF00831 Ribosomal_L29 48,582 20,285 3,546
PF06984 MRP-L47 3,694 1,951 671
CL0347 Tetraspannin 74,601 33,679 12,008 PF00335 Tetraspanin 55,661 24,914 8,605
PF03821 Mtp 2,661 844 205
PF04103 CD20 10,104 4,807 1,651
PF10754 DUF2569 2,862 1,327 721
PF13273 DUF4064 2,028 894 323
PF15860 DUF4728 1,279 894 503
CL0348 Phage_tail 29,937 14,065 6,129 PF02413 Caudo_TAP 10,422 3,295 1,194
PF04883 HK97-gp10_like 10,361 5,499 2,611
PF05069 Phage_tail_S 7,495 3,918 1,505
PF16778 Phage_tail_APC 1,655 1,354 831
CL0349 SLOG 149,942 81,154 17,621 PF02481 DNA_processg_A 49,460 30,250 7,877
PF03641 Lysine_decarbox 60,244 29,882 3,665
PF06908 YpsA 5,249 2,199 614
PF10686 YAcAr 5,764 2,214 739
PF11892 PpnN_C 5,266 1,339 82
PF12694 cpYpsA 1,881 1,542 600
PF18139 LSDAT_euk 15,812 7,066 1,983
PF18163 LD_cluster2 444 359 204
PF18171 LSDAT_prok 550 405 217
PF18178 TPALS 171 104 25
PF18180 LD_cluster3 329 235 82
PF18185 STALD 738 526 172
PF18306 LDcluster4 9,532 6,599 1,601
CL0350 PRC-barrel 130,943 67,047 13,914 PF03967 PRCH 1,070 687 76
PF05239 PRC 73,568 40,678 10,541
PF08683 CAMSAP_CKK 6,276 2,200 481
PF09939 DUF2171 3,122 1,571 346
PF20259 tRNA_Me_trans_M 47,942 22,580 2,543
CL0351 CHCH 34,918 17,292 5,231 PF02297 COX6B 7,924 3,908 1,218
PF05051 COX17 3,056 1,546 430
PF05676 NDUF_B7 2,865 1,382 370
PF06747 CHCH 10,056 4,731 1,455
PF08583 Cmc1 6,331 3,166 954
PF08991 MTCP1 1,774 1,035 347
PF10200 Ndufs5 1,845 923 284
PF16860 CX9C 1,303 693 222
CL0352 EsxAB 64,909 34,483 11,882 PF00823 PPE 13,836 7,520 1,709
PF00934 PE 13,777 6,635 2,430
PF04740 LXG 3,537 1,971 981
PF06013 WXG100 22,812 11,179 3,983
PF10774 DUF4226 858 531 154
PF10817 DUF2563 361 227 69
PF10824 T7SS_ESX_EspC 5,350 3,555 1,498
PF11328 DUF3130 269 61 27
PF17279 DUF5344 689 329 175
PF18625 EspB_PE 320 211 69
PF18879 EspA_EspE 892 567 254
PF21725 T7SS_signal 2,266 1,764 640
CL0353 TIMP-like 22,952 9,042 2,454 PF00965 TIMP 4,669 2,168 1,033
PF01759 NTR 16,842 6,130 1,255
PF03146 NtA 1,368 692 128
PF21556 AceES-2 74 57 43
CL0354 bBprotInhib 3,201 1,407 386 PF02974 Inh 3,108 1,392 376
PF09022 Staphostatin_A 55 9 7
PF09023 Staphostatin_B 35 6 3
CL0355 CheC-like 37,319 18,806 4,871 PF02154 FliM 17,267 7,166 1,514
PF04509 CheC 9,575 5,274 1,075
PF11813 DUF3334 1,063 403 39
PF13690 CheX 9,972 6,296 2,384
CL0356 AMP_N-like 117,885 58,180 10,859 PF01321 Creatinase_N 78,437 39,736 7,660
PF05195 AMP_N 34,423 16,252 2,454
PF14826 FACT-Spt16_Nlob 3,995 1,574 408
PF16189 Creatinase_N_2 21,088 9,604 1,794
CL0357 SMAD-FHA 213,280 116,945 43,233 PF00498 FHA 174,836 102,316 38,882
PF03166 MH2 13,985 4,048 1,152
PF04710 Pellino_FHA 3,559 975 247
PF09480 PrgH 1,068 254 119
PF10401 IRF-3 7,239 2,223 482
PF12538 FtsK_SpoIIIE_N 706 192 17
PF16697 Yop-YscD_cpl 9,881 6,663 3,195
PF17913 FHA_2 2,738 1,061 287
PF18221 MU2_FHA 57 34 19
CL0359 Intron-mat_II 151,171 21,896 4,731 PF01348 Intron_maturas2 131,544 10,909 1,575
PF08388 GIIM 19,625 10,987 3,157
CL0360 MTH1187-YkoF 17,053 8,712 1,279 PF01910 Thiamine_BP 15,369 7,730 1,098
PF07615 Ykof 1,682 994 244
CL0361 C2H2-zf 898,924 450,861 202,059 PF00096 zf-C2H2 538,566 258,040 115,841
PF02176 zf-TRAF 10,935 4,336 1,964
PF02892 zf-BED 16,872 10,680 6,929
PF04959 ARS2 4,420 1,850 502
PF05253 zf-U11-48K 5,504 2,884 1,265
PF05443 ROS_MUCR 10,708 5,546 1,002
PF05605 zf-Di19 11,147 3,972 1,380
PF06220 zf-U1 8,186 4,070 1,334
PF07535 zf-DBF 3,933 2,004 682
PF07776 zf-AD 17,161 11,109 5,595
PF08209 Sgf11 3,118 1,508 536
PF08790 zf-LYAR 3,263 1,845 691
PF09237 GAGA 325 174 94
PF09337 zf-H2C2 1,418 679 241
PF10394 Hat1_N 4,095 1,748 540
PF10426 zf-RAG1 13,105 1,073 106
PF11931 SF3a60_Prp9_C 4,027 1,622 402
PF12171 zf-C2H2_jaz 23,725 11,274 3,912
PF12756 zf-C2H2_2 7,923 4,031 1,357
PF12874 zf-met 63,298 28,757 13,675
PF12907 zf-met2 1,899 780 178
PF13465 zf-H2C2_2 26,394 16,150 10,620
PF13878 zf-C2H2_3 4,143 2,317 897
PF13894 zf-C2H2_4 31,533 16,729 11,023
PF13909 zf-H2C2_5 10,014 4,639 2,616
PF13912 zf-C2H2_6 81,978 40,576 21,017
PF13913 zf-C2HC_2 6,679 3,780 1,993
PF15269 zf-C2H2_7 1,347 504 76
PF15750 UBZ_FAAP20 315 219 104
PF15909 zf-C2H2_8 734 347 113
PF15965 zf-TRAF_2 2,483 877 277
PF16278 zf-C2HE 3,188 1,574 442
PF16293 zf-C2H2_9 86 46 12
PF16588 zf-C2H2_10 165 128 85
PF16622 zf-C2H2_11 5,142 2,006 930
PF16721 zf-H3C2 229 89 52
PF17017 zf-C2H2_aberr 69 33 26
PF17772 zf-MYST 13,949 5,951 1,621
PF17921 Integrase_H2C2 103,725 78,335 43,387
PF17979 zf-CRD 1,975 911 293
PF18048 TRAF6_Z2 657 87 15
PF18112 Zn-C2H2_12 2,358 705 182
PF18131 KN17_SH3 2,335 935 252
PF18217 Zap1_zf2 74 56 29
PF18279 zf-WRNIP1_ubi 203 59 14
PF18366 zf_ZIC 7,890 1,623 330
PF18387 zf_C2H2_ZHX 2,444 711 89
PF18408 zf_Hakai 1,610 448 147
PF18414 zf_C2H2_10 1,521 474 103
PF18439 zf_UBZ 2,899 1,412 347
PF18450 zf_C2H2_6 779 211 20
PF18508 zf_C2H2_13 70 50 22
PF18574 zf_C2HC_14 2,629 729 141
PF18608 XAF1_C 531 267 114
PF18868 zf-C2H2_3rep 596 237 77
PF20726 Nairovirus_Gn 369 111 42
PF21039 CEP104_ZnF 2,111 966 345
PF21137 ANM3_C2H2_Zf 2,730 1,111 274
PF21225 zf-C2H2_5 674 282 116
PF21276 ZNF512_C2H2 2,269 729 119
PF21336 ANM3_zf-C2H2 396 112 24
PF21341 TRAF2_zf 1,346 369 44
PF21361 Sina_ZnF 9,861 3,469 1,411
PF21366 TRAFD1-XIAF1_ZnF 2,451 1,141 420
PF21367 ZNF512_zf-C2H2 1,083 290 62
PF21816 Zap1_zf1 916 453 274
CL0362 RAMPS-Cas5-like 54,113 39,506 15,240 PF01881 Cas_Cas6_C 3,973 2,788 1,066
PF01905 DevR 2,194 1,538 322
PF03787 RAMPs 16,749 13,746 7,010
PF08798 CRISPR_assoc 4,526 2,857 896
PF09344 Cas_CT1975 4,356 2,590 446
PF09559 Cas6 993 739 239
PF09618 Cas_Csy4 1,598 1,025 260
PF09700 Cas_Cmr3 2,166 1,735 991
PF09704 Cas_Cas5d 10,334 6,984 1,356
PF10040 CRISPR_Cas6 4,706 3,647 1,898
PF17262 Cas6b_C 883 681 266
PF17952 Cas6_N 151 95 56
PF17953 Csm4_C 1,084 843 449
PF17955 Cas6b_N 849 654 250
PF18320 Csc2 812 532 120
PF19308 CRISPR_Cas6_N 891 600 198
PF21350 Cas6_I-A 1,504 1,121 451
PF21452 Cmr1_like_C 11 7 7
CL0363 H-int 44,432 29,811 14,455 PF01079 Hint 6,376 3,292 1,791
PF05203 Hom_end_hint 1,221 806 470
PF07591 PT-HINT 6,121 5,311 3,241
PF08517 AXH 3,654 1,130 380
PF10596 U6-snRNA_bdg 4,189 1,459 268
PF13403 Hint_2 10,487 8,703 4,156
PF14623 Vint 1,015 599 330
PF14890 Intein_splicing 11,498 8,646 3,962
CL0364 Leu-IlvD 483,898 232,491 36,493 PF00391 PEP-utilizers 111,104 53,364 9,708
PF00694 Aconitase_C 106,801 46,202 3,007
PF00988 CPSase_sm_chain 56,087 23,650 1,737
PF01989 AcnX_swivel_put 6,143 3,631 597
PF02225 PA 69,550 35,842 10,201
PF03737 RraA-like 45,219 22,961 3,055
PF04199 Cyclase 46,715 27,185 5,025
PF06434 Aconitase_2_N 12,538 2,999 154
PF09940 DUF2172 2,399 1,499 262
PF17676 Peptidase_S66C 27,332 15,158 2,747
CL0365 MurF-HprK_N 35,207 15,373 2,152 PF02603 Hpr_kinase_N 12,837 5,572 668
PF07085 DRTGG 22,368 9,802 1,503
CL0366 JAB 116,970 54,752 15,015 PF01398 JAB 39,801 13,948 3,920
PF03665 UPF0172 3,192 1,475 580
PF04002 RadC 46,684 24,844 5,740
PF05021 NPL4 4,690 1,950 471
PF14464 Prok-JAB 22,223 12,300 4,148
PF15659 Toxin-JAB1 324 256 202
PF20011 fvmJAB_N 50 35 16
CL0367 CI-2 10,063 5,390 1,871 PF00280 potato_inhibit 3,848 2,179 844
PF11720 Inhibitor_I78 6,213 3,211 1,027
CL0368 PhosC-NucP1 52,958 31,612 10,650 PF00882 Zn_dep_PLPC 8,195 4,755 1,956
PF02265 S1-P1_nuclease 11,324 7,116 2,227
PF04307 YdjM 28,517 16,804 5,567
PF09988 DUF2227 1,509 818 232
PF13803 DUF4184 3,408 2,125 712
CL0369 GHD 406,355 209,483 42,705 PF00686 CBM_20 15,415 8,218 2,970
PF02806 Alpha-amylase_C 46,353 22,353 2,729
PF02922 CBM_48 82,394 40,259 5,382
PF06964 Alpha-L-AF_C 20,614 11,166 1,777
PF07821 Alpha-amyl_C2 2,801 1,282 331
PF08533 Glyco_hydro_42C 8,940 4,632 722
PF09071 Alpha-amyl_C 42 17 4
PF09081 AMT4_dom_C 99 43 8
PF09083 DUF1923 14 3 1
PF09154 Alpha-amy_C_pro 3,502 1,487 233
PF09178 MGTA_C 17 6 2
PF09196 DUF1953 11 7 2
PF09244 Suc_Porlyase_C 289 51 11
PF09260 A_amylase_dom_C 2,330 1,211 270
PF09508 Lact_bio_phlase 1,560 633 80
PF10435 BetaGal_dom2 4,090 2,192 401
PF10438 Cyc-maltodext_C 3,752 2,338 340
PF11852 Pullul_strch_C 4,151 2,403 426
PF11941 DUF3459 28,726 14,584 1,893
PF12904 Collagen_bind_2 3,773 2,913 1,025
PF12980 DUF3864 144 97 13
PF14509 GH97_C 12,793 6,932 1,142
PF14702 hGDE_central 3,833 1,628 370
PF16561 AMPK1_CBM 18,361 10,503 4,352
PF16657 Malt_amylase_C 27,073 12,357 1,913
PF16757 Fucosidase_C 7,999 4,734 933
PF16874 Glyco_hydro_36C 12,700 6,374 1,019
PF17189 Glyco_hydro_30C 13,328 7,715 1,818
PF17386 LBP_C 1,471 576 68
PF17387 Glyco_hydro_59M 1,645 532 114
PF17450 Melibiase_2_C 2,459 910 178
PF17451 Glyco_hyd_101C 1,521 635 202
PF17677 Glyco_hydro38C2 17,244 10,058 2,975
PF17801 Melibiase_C 16,790 9,951 2,105
PF17834 GHD 6,783 2,861 544
PF18033 SpuA_C 975 340 97
PF18120 DUF5597 2,690 1,590 335
PF18206 Porphyrn_cat_1 439 358 171
PF18230 Glyc_hyd_38C_2 74 28 4
PF18310 DUF5605 1,334 862 153
PF18390 GlgX_C 1,992 336 61
PF18564 Glyco_hydro_5_C 4,726 2,772 901
PF18612 Bac_A_amyl_C 450 283 66
PF18675 HepII_C 309 219 108
PF21156 ISOA1-3_C 3,464 2,033 328
PF21260 Laman-like_dom 3,247 1,462 335
PF21331 Isoamylase_C 981 603 155
PF21365 Glyco_hydro_31_3rd 55,695 27,630 6,168
PF21653 pulA_all-beta 3,496 1,482 328
PF21702 GLGE_C 9,786 4,709 330
CL0370 Uteroglobin 1,776 1,013 351 PF01099 Uteroglobin 1,208 689 253
PF09252 Feld-I_B 260 167 57
PF20490 SCGB3A 305 158 41
CL0371 Inovirus-Coat 881 623 361 PF05356 Phage_Coat_B 699 511 300
PF19199 Phage_coatGP8 180 112 61
CL0373 Phage-coat 67,273 31,551 9,738 PF03864 Phage_cap_E 7,575 3,277 1,132
PF04454 Linocin_M18 3,289 1,630 341
PF05065 Phage_capsid 23,940 13,021 4,440
PF05125 Phage_cap_P2 4,371 1,240 261
PF06673 L_lactis_ph-MCP 83 17 16
PF07068 Gp23 6,713 1,935 228
PF08967 ENCP4 145 70 8
PF09950 DUF2184 2,495 938 328
PF10124 Mu-like_gpT 3,850 2,299 857
PF11651 P22_CoatProtein 2,196 1,021 363
PF17236 DUF5309 1,953 1,420 594
PF19307 SrpI-like 5,033 1,735 115
PF19774 DUF6260 689 238 86
PF19821 Phage_capsid_2 1,539 1,091 447
PF20036 Gp13-like 1,360 540 177
PF20911 GP7 1,137 705 255
PF21703 Gp10A-like 891 384 132
CL0374 PEP-carboxyk 66,497 29,248 3,605 PF00821 PEPCK_GTP 20,455 8,166 713
PF01293 PEPCK_ATP 28,357 12,137 1,293
PF07475 Hpr_kinase_C 17,682 8,945 1,599
CL0375 Transporter 104,789 38,966 11,448 PF00029 Connexin 18,548 5,367 815
PF00822 PMP22_Claudin 31,621 11,090 2,557
PF00876 Innexin 12,453 6,120 2,747
PF06653 Claudin_3 449 357 217
PF06687 SUR7 8,530 4,972 1,737
PF07062 Clc-like 954 612 287
PF07344 Amastin 1,097 543 242
PF07803 GSG-1 2,991 851 149
PF10242 L_HMGIC_fpl 7,156 2,374 727
PF12351 Fig1 1,528 695 315
PF12534 Pannexin_like 4,218 726 176
PF13903 Claudin_2 12,120 4,306 1,317
PF14985 TM140 589 348 47
PF15108 TMEM37 428 163 35
PF18800 Atthog 1,356 354 102
PF20517 TMEM127 908 297 130
CL0376 Oxa1 127,959 55,927 10,677 PF00344 SecY 59,286 20,763 2,391
PF01956 EMC3_TMCO1 9,403 3,921 1,172
PF02096 60KD_IMP 59,268 31,244 7,115
CL0377 FAH 144,201 73,042 8,694 PF01557 FAA_hydrolase 141,630 71,748 8,440
PF11010 DUF2848 2,569 1,294 254
CL0378 ANL 776,904 420,154 105,125 PF00501 AMP-binding 750,536 404,366 101,286
PF03321 GH3 19,624 11,266 2,571
PF04443 LuxE 5,464 3,571 649
PF16177 ACAS_N 72,687 32,479 2,953
CL0379 PgaPase 13,868 7,108 1,959 PF01470 Peptidase_C15 13,782 7,044 1,927
PF06162 PgaPase_1 84 65 38
CL0380 IDO-like 24,339 12,063 2,137 PF01231 IDO 7,433 3,959 1,097
PF03301 Trp_dioxygenase 15,681 7,505 899
PF07014 Hs1pro-1_C 603 290 72
PF08933 PrnB 620 311 71
CL0381 Metallo-HOrase 617,234 347,279 71,733 PF00753 Lactamase_B 388,887 221,600 48,916
PF02112 PDEase_II 2,430 1,451 387
PF12706 Lactamase_B_2 158,601 88,765 17,795
PF13483 Lactamase_B_3 33,150 20,432 4,462
PF13691 Lactamase_B_4 4,585 2,491 848
PF14597 Lactamase_B_5 983 637 171
PF16123 HAGH_C 23,167 11,180 1,397
PF16661 Lactamase_B_6 15,682 7,039 1,711
PF17030 Beta_lactamase3 33 29 22
PF19583 ODP 20,569 10,674 1,218
CL0382 DNA-mend 425,897 236,491 79,839 PF00589 Phage_integrase 386,709 217,214 73,494
PF01028 Topoisom_I 20,522 8,998 1,376
PF05202 Flp_C 41 19 15
PF11917 DUF3435 3,971 3,094 1,922
PF12012 DUF3504 7,647 3,036 1,174
PF12835 Integrase_1 3,482 1,436 363
PF13009 Integrase_2 601 457 221
PF16684 Telomere_res 667 406 227
PF16787 NDC10_II 1,788 1,465 874
PF16795 Phage_integr_3 514 429 267
CL0383 PheT-TilS 84,780 45,865 11,372 PF03483 B3_4 60,762 31,270 5,814
PF11734 TilS_C 24,016 14,595 5,559
CL0385 Hydrophilin 8,734 3,719 977 PF00477 LEA_5 925 461 137
PF10685 KGG 7,817 3,266 852
CL0387 DHFred 146,905 85,594 13,573 PF00186 DHFR_1 42,741 22,483 4,264
PF01872 RibD_C 104,162 63,119 9,349
CL0388 FadR-C 244,291 111,909 24,847 PF07729 FCD 241,628 111,242 24,732
PF07840 FadR_C 2,661 670 129
CL0389 TRAF 39,825 16,312 6,026 PF00917 MATH 19,768 9,047 3,590
PF03145 Sina_TRAF 5,987 1,803 494
PF11529 AvrL567-A 12 3 2
PF11584 Toxin_ToxA 53 4 4
PF21355 TRAF-mep_MATH 14,000 5,459 1,942
CL0391 CAP_C-like 13,303 6,115 2,170 PF07986 TBCC 7,304 3,618 1,500
PF08603 CAP_C 5,997 2,497 670
CL0392 Chaperone-J 296,390 145,560 43,647 PF00226 DnaJ 292,136 143,483 43,099
PF03656 Pam16 4,252 2,078 566
CL0394 DsrEFH-like 51,773 27,492 5,207 PF02635 DsrE 35,962 19,335 3,939
PF04077 DsrH 6,024 2,929 689
PF13686 DrsE_2 9,784 5,256 654
CL0395 Tubby_C 38,897 19,510 6,564 PF01167 Tub 12,348 5,268 1,512
PF03803 Scramblase 9,486 5,222 1,926
PF04525 LOR 11,960 6,050 1,901
PF12043 DUF3527 2,158 1,070 428
PF12396 DUF3659 1,479 769 286
PF21784 Bflower 820 648 315
PF21785 Bflower_2 652 501 220
CL0396 Marvel-like 42,733 19,920 5,553 PF01284 MARVEL 29,979 13,423 3,416
PF04535 CASP_dom 12,532 6,305 2,024
PF21786 Bflower_3 219 192 113
CL0397 TusA-like 50,495 27,226 4,821 PF01206 TusA 41,960 21,810 3,578
PF10006 DUF2249 7,935 5,219 1,220
PF16514 NADH-UOR_E 597 197 27
CL0398 RMMBL_DRMBL 78,144 37,867 6,422 PF07521 RMMBL 69,979 33,546 4,928
PF07522 DRMBL 8,163 4,321 1,495
CL0399 Asp-glut_race 93,809 48,761 8,445 PF01177 Asp_Glu_race 77,454 40,306 6,711
PF07302 AroM 2,418 1,092 370
PF14669 Asp_Glu_race_2 728 435 99
PF17645 Amdase 13,205 6,928 1,269
CL0400 GG-leader 3,091 1,452 751 PF03047 ComC 615 247 150
PF04369 Lactococcin 117 48 35
PF04604 L_biotic_typeA 236 108 46
PF08129 Antimicrobial17 13 8 5
PF10439 Bacteriocin_IIc 1,129 456 295
PF11632 LcnG-beta 10 5 4
PF14406 Bacteroid_pep 98 67 29
PF16934 Mersacidin 291 158 83
PF19155 DUF5837 175 121 32
PF19392 DUF5967 26 14 5
PF19409 Thiopep_pre 370 223 77
CL0401 AsmA-like 88,260 50,551 23,072 PF01203 T2SSN 5,050 2,800 1,078
PF04357 TamB 26,946 16,376 7,318
PF05170 AsmA 25,508 13,281 6,089
PF05359 DUF748 9,108 5,595 2,680
PF13109 AsmA_1 1,628 596 381
PF13116 DUF3971 13,659 6,904 2,969
PF13502 AsmA_2 26,536 16,305 7,580
CL0402 Cdc48_2-like 27,577 11,143 2,365 PF02933 CDC48_2 16,572 6,059 833
PF03152 UFD1 7,170 3,250 982
PF09262 PEX-1N 3,833 1,835 551
CL0403 ADC-like 18,746 11,181 2,561 PF06314 ADC 10,825 5,652 1,392
PF09844 DUF2071 7,919 5,529 1,169
CL0404 BPD_transp_1 1,971,999 884,702 136,448 PF00528 BPD_transp_1 1,568,535 654,923 73,179
PF02687 FtsX 345,469 198,799 54,698
PF03739 LptF_LptG 56,564 30,616 8,326
PF07242 DUF1430 1,441 368 249
CL0405 DNA_b-psBarrel 37,158 18,564 7,789 PF02362 B3 33,476 16,363 6,729
PF03754 At2g31720-like 2,069 1,235 741
PF09217 EcoRII-N 862 407 119
PF18243 BfiI_DBD 40 30 6
PF20731 RE_NgoFVII_C 706 533 202
CL0406 YjbJ-CsbD-like 36,126 15,496 2,595 PF05532 CsbD 27,429 13,448 2,229
PF05957 DUF883 8,695 2,048 366
CL0407 TBP-like 65,869 30,559 7,533 PF00352 TBP 15,272 5,667 1,730
PF02486 Rep_trans 4,832 1,645 791
PF02675 AdoMet_dc 18,249 9,079 1,967
PF05144 Phage_CRI 1,322 841 443
PF06029 AlkA_N 11,477 5,567 775
PF07934 OGG_N 9,192 5,477 1,453
PF11858 DUF3378 3,235 1,337 222
PF17950 SpmSyn_N 925 310 51
PF18106 Rol_Rep_N 2,831 553 244
PF18446 DUF5611 1,249 592 79
CL0408 PUP 222,599 112,645 22,929 PF01048 PNP_UDP_1 141,990 71,489 14,731
PF01195 Pept_tRNA_hydro 49,830 25,683 4,517
PF04414 tRNA_deacylase 3,458 2,153 631
PF06516 NUP 3,562 1,611 312
PF09754 PAC2 23,416 11,461 2,611
PF10423 AMNp_N 7,663 2,177 115
PF10450 POC1 108 88 52
CL0409 GAP 160,195 65,238 16,149 PF00616 RasGAP 30,130 11,320 2,497
PF00620 RhoGAP 128,355 52,923 13,300
PF08101 Msb1-Mug8_dom 1,712 1,001 357
CL0410 LEF-8-like 101,332 27,834 4,226 PF00562 RNA_pol_Rpb2_6 100,723 27,659 4,191
PF04941 LEF-8 607 175 35
CL0411 Vir 18,903 12,358 4,189 PF05795 Plasmodium_Vir 13,022 8,714 3,477
PF06022 Cir_Bir_Yir 5,886 3,652 720
CL0412 Frag1-like 25,318 14,996 5,382 PF06197 DUF998 12,198 8,597 3,183
PF10277 Frag1 13,118 6,400 2,204
CL0413 Toprim-like 346,926 152,592 29,163 PF01751 Toprim 185,580 71,423 8,037
PF07057 TraI_C 1,473 302 123
PF09664 DUF2399 2,208 1,609 623
PF09983 JetD_C 4,653 3,188 1,309
PF11536 DUF3226 2,059 1,365 658
PF12965 DUF3854 2,248 1,570 911
PF13155 Toprim_2 56,474 28,504 9,117
PF13362 Toprim_3 11,643 5,763 2,101
PF13662 Toprim_4 57,131 25,672 2,850
PF20469 OLD-like_TOPRIM 14,068 8,650 2,609
PF21180 TOP6A-Spo11_Toprim 9,381 4,809 1,554
CL0414 TerB 39,212 20,100 5,153 PF04391 DUF533 7,122 2,941 671
PF05099 TerB 32,089 17,179 4,529
CL0416 Anoctamin-like 53,567 24,189 7,090 PF02714 RSN1_7TM 20,534 9,630 2,747
PF04547 Anoctamin 24,962 10,661 3,392
PF07810 TMC 8,070 3,902 957
CL0417 BIR-like 19,008 9,638 4,214 PF00653 BIR 14,962 7,652 3,453
PF07967 zf-C3HC 3,964 1,927 723
PF08600 Rsm1 2,274 1,106 342
CL0418 GIY-YIG 128,571 77,694 21,178 PF01541 GIY-YIG 107,000 62,993 14,208
PF01986 DUF123 3,709 2,816 1,271
PF09517 RE_Eco29kI 715 581 216
PF10544 T5orf172 8,163 5,411 2,976
PF13455 MUG113 6,776 4,612 2,153
PF19239 GIY_YIG_domain 575 327 158
PF19835 SegE_GIY-YIG 630 283 130
PF20815 GIY_YIG_2 1,006 741 324
CL0419 T3SS-Chaperone 16,691 8,432 3,422 PF02050 FliJ 14,774 7,620 3,076
PF02090 SPAM 651 132 62
PF07321 YscO 619 342 151
PF09486 HrpB7 373 152 58
PF16789 YscO-like 269 186 75
CL0420 GlpM-like 3,474 1,111 287 PF06942 GlpM 2,253 413 67
PF11345 DUF3147 1,219 698 224
CL0421 LppaM 14,512 7,062 4,254 PF06474 MLTD_N 1,060 122 11
PF08139 LPAM_1 5,258 2,778 2,173
PF13627 LPAM_2 8,191 4,162 2,071
CL0422 Fibrinogen_C 56,862 26,631 9,598 PF00147 Fibrinogen_C 42,684 21,465 8,351
PF01410 COLFI 14,188 5,178 1,275
CL0423 AhpD-like 128,433 64,763 9,410 PF02627 CMD 123,599 63,318 9,016
PF04636 PA26 4,832 1,446 405
CL0424 T3SS-hook 54,843 33,667 15,807 PF02120 Flg_hook 25,743 16,454 9,860
PF05258 DciA 28,651 16,988 5,827
PF09483 HpaP 446 225 122
CL0425 ComplexI-N 572,247 182,787 24,421 PF00146 NADHdh 114,859 35,360 4,058
PF00361 Proton_antipo_M 457,304 147,382 20,375
PF10125 NADHdeh_related 206 83 11
CL0426 HRDC-like 80,073 38,064 7,918 PF00570 HRDC 68,687 32,809 6,185
PF03874 RNA_pol_Rpb4 10,399 4,867 1,545
PF08203 RNA_polI_A14 156 116 63
PF11408 Helicase_Sgs1 90 71 33
PF11637 UvsW-1 458 49 8
PF18305 DNA_pol_A_exoN 5,445 2,426 218
PF21293 RNAseD_HRDC_C 3,675 997 199
CL0428 TolA-TonB-Cterm 105,528 66,041 31,617 PF03544 TonB_C 82,330 53,300 26,511
PF06519 TolA 4,024 1,296 291
PF13103 TonB_2 19,269 11,565 5,100
CL0429 UcrQ-like 3,351 1,700 500 PF02939 UcrQ 2,867 1,453 399
PF10890 Cyt_b-c1_8 482 247 101
CL0430 CopD_like 79,149 42,121 9,462 PF03653 UPF0093 16,818 8,409 734
PF04247 SirB 5,223 2,447 516
PF05425 CopD 23,691 12,331 3,216
PF07457 DUF1516 1,760 783 168
PF08592 Anthrone_oxy 11,483 7,406 2,025
PF09980 DUF2214 2,922 1,346 284
PF10027 DUF2269 6,761 3,635 899
PF13664 DUF4149 9,044 5,057 1,526
PF14007 YtpI 1,438 707 125
CL0431 PF 171,818 64,779 16,405 PF00235 Profilin 8,595 3,786 1,251
PF01217 Clat_adaptor_s 38,273 11,534 2,699
PF03259 Robl_LC7 34,051 12,731 3,196
PF03456 uDENN 30,472 12,700 1,988
PF04086 SRP-alpha_N 4,101 1,581 337
PF04099 Sybindin 7,153 3,068 914
PF04628 Sedlin_N 7,484 3,164 934
PF08923 MAPKK1_Int 1,757 740 320
PF09201 SRX 59 36 1
PF09426 Nyv1_longin 57 34 8
PF13774 Longin 18,119 6,602 1,732
PF14636 FNIP_N 3,639 1,176 252
PF15001 AP-5_subunit_s1 749 348 119
PF16672 LAMTOR5 1,560 692 302
PF16818 SLM4 109 76 39
PF18639 Longin_2 119 83 48
PF19031 Intu_longin_1 6,087 2,658 886
PF19032 Intu_longin_2 3,031 1,067 361
PF19033 Intu_longin_3 4,090 1,408 419
PF19036 Fuz_longin_1 7,218 3,036 939
PF19037 Fuz_longin_2 7,677 2,844 827
PF19038 Fuz_longin_3 6,561 2,573 699
CL0433 SPFH 182,183 83,511 13,480 PF01145 Band_7 170,088 77,080 12,544
PF11978 MVP_shoulder 1,759 751 173
PF13421 Band_7_1 10,333 5,685 772
CL0435 NPR 6,923 3,075 1,066 PF03666 NPR3 3,539 1,525 537
PF06218 NPR2 3,382 1,550 530
CL0436 FliG 66,099 31,457 6,562 PF01706 FliG_C 21,875 9,037 1,952
PF03448 MgtE_N 43,286 21,721 4,123
PF14841 FliG_M 20,925 8,309 1,537
PF14842 FliG_N 20,383 7,917 1,346
CL0437 EF-G_C 251,556 89,862 9,251 PF00679 EFG_C 191,299 66,556 5,611
PF09186 DUF1949 17,468 7,681 1,278
PF09377 SBDS_domain_II 7,603 3,119 594
PF14492 EFG_III 105,032 39,980 3,880
PF16658 RF3_C 26,989 7,784 357
PF18093 Trm5_N 1,968 1,292 352
PF20268 SBDS_C 6,267 2,739 430
CL0439 NusG-like 64,293 26,794 5,326 PF02357 NusG 55,900 22,873 4,216
PF03439 Spt5-NGN 8,415 3,941 1,124
CL0441 AlbA 49,774 29,732 10,024 PF01918 Alba 10,351 5,134 1,448
PF04232 SpoVS 4,910 1,533 324
PF04326 SLFN_AlbA_2 32,295 21,774 7,748
PF12328 Rpp20 2,214 1,292 510
CL0442 Tubulin_C 110,309 38,156 6,024 PF03953 Tubulin_C 54,120 14,298 3,209
PF12327 FtsZ_C 54,038 23,003 2,659
PF21011 CetZ_C 2,064 832 147
PF21493 TubZ_C 83 23 9
CL0445 SNARE-fusion 51,998 21,822 6,524 PF00804 Syntaxin 18,049 7,786 2,153
PF00957 Synaptobrevin 26,857 11,223 3,634
PF14523 Syntaxin_2 7,172 2,893 783
CL0446 Bacteriocin_TLN 2,741 1,515 529 PF03515 Cloacin 377 123 78
PF06958 Pyocin_S 2,469 1,421 462
CL0447 Hypoth_1 12,428 6,052 1,217 PF06993 DUF1304 9,378 4,377 433
PF12650 DUF3784 3,048 1,675 784
CL0448 Cargo_bd_muHD 34,433 11,504 2,750 PF00928 Adap_comp_sub 27,567 8,373 2,144
PF10291 muHD 6,864 3,133 609
CL0449 G-PATCH 47,497 23,252 8,228 PF01585 G-patch 44,144 21,259 7,384
PF12656 G-patch_2 3,354 1,997 854
CL0451 FnI-like 41,714 16,903 4,819 PF00039 fn1 3,962 1,409 152
PF00093 VWC 29,574 10,223 2,461
PF05375 Pacifastin_I 1,410 1,033 761
PF05825 PSP94 2,239 1,336 370
PF12714 TILa 4,599 2,958 1,121
CL0452 Tropomyosin-lke 21,766 8,059 1,750 PF00261 Tropomyosin 17,144 6,577 1,487
PF16526 CLZ 4,635 1,493 271
CL0453 Apoptosis-Inhib 52,627 22,240 4,257 PF01027 Bax1-I 42,950 17,592 3,567
PF12811 BaxI_1 9,675 4,648 690
CL0456 Golgi_traff 7,982 3,354 1,239 PF09742 Dymeclin 4,127 1,687 759
PF12722 Hid1 3,909 1,763 555
CL0457 4HB_MCP 90,959 44,914 14,569 PF02203 TarH 15,541 4,855 1,335
PF05227 CHASE3 20,166 12,328 4,265
PF12729 4HB_MCP_1 49,257 26,477 9,041
PF16591 HBM 4,299 1,086 280
PF21689 TorS_sensor_domain 1,737 265 77
CL0458 IIaaRS-ABD 226,063 102,122 11,718 PF03129 HGTP_anticodon 203,215 92,310 9,442
PF04427 Brix 19,581 8,389 1,924
PF12745 HGTP_anticodon2 3,264 1,429 362
CL0459 BRCT-like 113,142 57,753 15,573 PF00533 BRCT 88,321 44,745 10,878
PF08630 Dfp1_Him1_M 1,524 831 272
PF12738 PTCB-BRCT 14,366 7,321 2,831
PF16508 NIBRIN_BRCT_II 2,453 1,226 413
PF16589 BRCT_2 15,677 8,239 3,286
PF16759 LIG3_BRCT 1,466 612 161
PF16770 RTT107_BRCT_5 6,771 3,270 1,320
PF16771 RTT107_BRCT_6 145 113 62
PF18428 BRCT_3 1,684 862 320
PF21243 ECT2_BRCT0 2,009 618 130
PF21298 TopBP1_BRCT0 1,113 539 123
CL0461 Metallothionein 5,795 2,439 672 PF00131 Metallothio 2,339 805 248
PF01439 Metallothio_2 1,660 806 242
PF02067 Metallothio_5 135 70 31
PF02068 Metallothio_PEC 278 163 54
PF02069 Metallothio_Pro 1,248 530 71
PF05522 Metallothio_6 38 21 7
PF07846 Metallothio_Cad 35 24 11
PF11403 Yeast_MT 21 4 2
PF12749 Metallothio_Euk 21 12 6
PF12809 Metallothi_Euk2 11 5 1
CL0462 TPA-repeat 5,561 2,051 521 PF08920 SF3b1 3,984 1,270 215
PF12815 CTD 1,576 782 307
CL0464 5_3_exonuc_C 85,391 43,175 8,785 PF00867 XPG_I 22,805 12,561 4,180
PF01367 5_3_exonuc 60,376 29,492 4,133
PF09293 RNaseH_C 681 196 71
PF12813 XPG_I_2 1,525 926 402
CL0465 Ank 629,745 341,941 161,555 PF00023 Ank 207,449 116,552 60,720
PF11900 DUF3420 1,832 644 113
PF11929 DUF3447 1,324 1,311 737
PF12796 Ank_2 567,847 305,459 141,774
PF13606 Ank_3 8,039 4,929 3,580
PF13637 Ank_4 122,959 70,172 37,594
PF13857 Ank_5 24,177 14,019 8,662
PF18418 AnkUBD 1,479 362 82
CL0466 PDZ-like 526,048 265,694 66,532 PF00595 PDZ 243,495 102,445 25,445
PF04495 GRASP55_65 5,068 2,309 625
PF09007 EBP50_C 2,220 824 125
PF12812 PDZ_1 3,383 1,673 461
PF13180 PDZ_2 162,938 95,376 25,876
PF14685 Tricorn_PDZ 7,611 5,078 872
PF17815 PDZ_3 4,805 2,623 939
PF17816 PDZ_4 187 164 113
PF17817 PDZ_5 4,696 1,920 505
PF17820 PDZ_6 129,890 74,683 22,991
PF19805 DUF6288 807 665 289
CL0469 l-integrase_N 204,280 110,706 32,071 PF02899 Phage_int_SAM_1 101,016 56,093 11,572
PF03930 Flp_N 27 16 11
PF12834 Phage_int_SAM_2 2,679 1,041 303
PF13102 Phage_int_SAM_5 36,053 16,673 7,194
PF13495 Phage_int_SAM_4 24,410 15,535 5,598
PF14659 Phage_int_SAM_3 39,060 21,426 8,630
PF18644 Phage_int_SAM_6 1,003 157 30
PF21400 Ndc10_N 54 39 19
CL0470 ThrE 30,270 12,904 3,404 PF06738 ThrE 21,759 9,510 2,493
PF12821 ThrE_2 18,601 7,834 1,909
CL0471 DUF362 37,814 27,273 7,239 PF04015 DUF362 23,767 17,473 4,930
PF09861 Lar_N 14,045 9,807 2,369
CL0472 Peptidase_U 141,069 87,352 37,962 PF02517 Rce1-like 118,589 74,274 33,228
PF06105 Aph-1 3,085 1,257 429
PF10086 YhfC 2,811 1,295 665
PF13367 PrsW-protease 16,580 10,526 3,642
CL0474 SICA_like 975 632 470 PF12878 SICA_beta 613 325 207
PF12887 SICA_alpha 704 478 368
CL0475 Cyclophil-like 219,280 111,389 23,166 PF00160 Pro_isomerase 155,066 77,641 16,147
PF02626 CT_A_B 28,736 14,817 2,623
PF02682 CT_C_D 27,972 14,389 2,423
PF04126 Cyclophil_like 3,103 2,167 464
PF05913 MupG_C 4,826 1,708 381
PF12903 DUF3830 3,491 1,433 209
PF18050 Cyclophil_like2 4,731 3,327 1,352
CL0476 tRNA-IECD_N 8,438 4,752 1,335 PF02778 tRNA_int_endo_N 4,864 2,872 646
PF12928 tRNA_int_end_N2 3,573 1,881 690
CL0477 TRD 70,021 57,315 30,118 PF01420 Methylase_S 54,152 45,011 25,616
PF12950 TaqI_C 7,963 6,167 2,783
PF18135 Type_ISP_C 7,903 6,137 1,719
CL0478 ATPase_I_AtpR 15,670 7,927 3,108 PF03899 ATP-synt_I 14,164 6,739 2,518
PF12966 AtpR 1,504 1,189 593
CL0479 PLD 231,212 120,637 29,984 PF00614 PLDc 18,731 8,768 2,155
PF03265 DNase_II 5,789 3,392 1,421
PF06087 Tyr-DNA_phospho 6,197 3,435 1,381
PF07894 FAM83 6,800 2,630 592
PF09565 RE_NgoFVII 932 698 375
PF11495 Regulator_TrmB 5,938 3,057 913
PF13090 PP_kinase_C 33,989 14,722 1,504
PF13091 PLDc_2 112,242 59,243 16,630
PF13918 PLDc_3 5,021 1,638 481
PF16565 MIT_C 2,509 1,354 367
PF17941 PP_kinase_C_1 35,866 14,898 1,514
PF19054 DUF5753 38,540 23,742 4,659
PF21806 DUF6879 4,309 3,097 625
CL0481 HUH 73,575 48,124 16,582 PF01797 Y1_Tnp 61,762 41,065 13,119
PF04986 Y2_Tnp 11,811 7,059 3,463
CL0482 Prolamin 40,227 18,560 6,884 PF00234 Tryp_alpha_amyl 10,979 5,106 1,968
PF05617 Prolamin_like 5,299 2,220 909
PF13016 Gliadin 3,599 557 90
PF14368 LTP_2 14,114 7,931 3,304
PF14547 Hydrophob_seed 6,245 2,905 874
CL0484 Peroxisome 31,552 14,250 4,074 PF02453 Reticulon 15,922 6,958 2,035
PF04842 DUF639 2,076 842 188
PF06398 Pex24p 6,244 3,345 1,205
PF08372 PRT_C 7,310 3,114 661
CL0486 Fer2 398,603 196,815 25,578 PF00111 Fer2 225,468 113,670 14,746
PF01799 Fer2_2 95,245 50,720 4,552
PF10418 DHODB_Fe-S_bind 32,041 18,954 2,940
PF13085 Fer2_3 50,345 17,596 1,407
PF13510 Fer2_4 82,400 42,255 5,465
CL0487 FKBP 368,121 184,440 48,111 PF00254 FKBP_C 165,332 79,643 19,519
PF00639 Rotamase 44,042 25,661 9,071
PF01272 GreA_GreB 70,987 31,410 3,987
PF09122 DUF1930 43 23 7
PF12202 OSR1_C 11,519 5,161 946
PF13145 Rotamase_2 26,761 17,084 8,191
PF13616 Rotamase_3 54,021 30,135 10,383
PF14801 GCD14_N 7,071 2,825 296
PF16109 DUF4827 886 413 130
PF18023 FKBP_N_2 252 165 68
PF18046 FKBP26_C 1,047 620 160
CL0488 FixH-like 18,678 11,579 4,277 PF05751 FixH 11,515 7,240 2,293
PF13115 YtkA 7,166 4,342 2,006
CL0489 SAF 218,052 116,398 39,430 PF00856 SET 122,425 66,463 25,725
PF08666 SAF 54,747 30,251 6,516
PF13144 ChapFlgA 16,759 9,591 3,984
PF16976 RcpC 17,129 10,242 3,224
PF21182 FOG1-like_PR 1,613 554 118
PF21549 PRDM2_PR 18,242 6,750 2,126
CL0490 PepSY_TM-like 44,103 23,990 5,643 PF03929 PepSY_TM 39,420 21,473 5,165
PF16357 PepSY_TM_like_2 4,681 2,524 501
CL0491 LYR-like 30,301 15,531 4,809 PF05347 Complex1_LYR 19,845 10,073 3,211
PF13232 Complex1_LYR_1 55 31 13
PF13233 Complex1_LYR_2 6,666 3,439 919
PF20180 UQCC2_CBP6 2,532 1,256 403
PF20263 LYRM2-like 1,204 794 363
CL0492 S4 299,083 126,393 16,450 PF00163 Ribosomal_S4 76,349 17,570 1,191
PF01479 S4 281,010 118,188 15,326
PF13275 S4_2 15,065 7,233 838
PF16714 TyrRSs_C 910 419 90
CL0493 PTS_EIIC 101,304 31,057 4,544 PF02378 PTS_EIIC 94,973 28,520 4,245
PF13303 PTS_EIIC_2 6,329 2,537 300
CL0494 DnaA_N 83,708 39,470 7,364 PF02033 RBFA 43,272 21,697 4,405
PF11490 DNA_pol3_a_NII 4,845 1,519 184
PF11638 DnaA_N 35,588 16,254 2,775
CL0496 Tad-like 63,950 43,368 17,558 PF07811 TadE 36,836 24,839 9,898
PF09977 Tad_C 2,594 1,565 699
PF13400 Tad 25,159 17,543 7,361
PF16964 TadF 644 348 138
CL0497 GST_C 264,291 127,350 22,941 PF00043 GST_C 117,675 56,809 10,700
PF04399 Glutaredoxin2_C 2,254 770 195
PF09635 MetRS-N 103 58 8
PF11801 Tom37_C 70 51 25
PF13410 GST_C_2 98,144 48,962 8,397
PF14497 GST_C_3 32,061 17,229 5,626
PF14834 GST_C_4 2,328 666 68
PF16865 GST_C_5 433 245 124
PF17171 GST_C_6 11,409 5,352 1,695
CL0498 Nribosyltransf 24,468 13,518 4,094 PF02267 Rib_hydrolayse 2,063 882 331
PF05014 Nuc_deoxyrib_tr 9,247 5,374 1,613
PF09152 DUF1937 450 303 169
PF11071 Nuc_deoxyri_tr3 2,695 1,512 80
PF14359 DUF4406 4,155 2,328 1,083
PF15891 Nuc_deoxyri_tr2 2,630 1,688 656
PF20309 DRHyd-ASK 3,221 1,436 182
CL0499 O-anti_assembly 92,323 63,732 36,601 PF01901 O_anti_polymase 665 434 201
PF04932 Wzy_C 87,139 61,442 35,170
PF06899 WzyE 1,594 260 59
PF13425 O-antigen_lig 1,462 582 340
PF14296 O-ag_pol_Wzy 1,460 1,017 836
CL0500 Glycine-zipper 88,222 41,653 10,529 PF04306 DUF456 10,756 6,422 1,327
PF05433 Rick_17kDa_Anti 25,467 11,500 2,918
PF06897 DUF1269 4,692 2,696 683
PF10247 Romo1 3,053 1,162 310
PF11981 DUF3482 3,062 1,401 326
PF13436 Gly-zipper_OmpA 1,221 791 293
PF13441 Gly-zipper_YMGG 8,556 4,113 1,312
PF13488 Gly-zipper_Omp 15,160 7,563 1,970
PF16587 DUF5061 226 185 111
PF16998 17kDa_Anti_2 4,216 2,193 739
PF19029 DUF883_C 10,926 3,450 1,022
PF20721 C19orf12 1,713 932 353
PF21724 DUF6861 793 355 169
CL0502 STAS 202,403 112,555 32,985 PF01740 STAS 159,201 85,839 23,370
PF11964 SpoIIAA-like 8,435 5,576 2,089
PF13466 STAS_2 31,144 18,724 7,621
PF14213 DUF4325 3,677 2,881 1,204
CL0504 Phage_barrel 136,303 57,172 19,797 PF04630 Phage_TTP_1 1,540 633 253
PF04985 Phage_tube 6,149 2,121 553
PF05354 Phage_attach 845 135 60
PF05521 Phage_H_T_join 10,656 6,043 2,386
PF05709 Sipho_tail 5,027 2,317 1,110
PF05954 Phage_GPD 36,928 17,955 5,570
PF06199 Phage_tail_2 5,045 2,738 662
PF06488 L_lac_phage_MSP 489 97 42
PF06605 Prophage_tail 5,883 3,255 1,849
PF06763 Minor_tail_Z 2,273 834 409
PF06841 Phage_T4_gp19 12,261 6,459 1,497
PF08710 CoV_NSP9 8,046 465 58
PF08813 Phage_tail_3 1,537 583 187
PF09096 Phage-tail_2 410 42 9
PF09097 Phage-tail_1 459 47 10
PF09393 DUF2001 1,853 991 227
PF11091 T4_tail_cap 663 102 45
PF11514 DUF3219 363 237 47
PF12206 DUF3599 205 87 33
PF13550 Phage-tail_3 10,956 6,461 2,424
PF13856 Gifsy-2 470 95 23
PF14594 Sipho_Gp37 1,866 1,074 596
PF16460 Phage_TTP_11 637 280 62
PF16461 Phage_TTP_12 2,380 873 348
PF16463 Phage_TTP_13 198 72 17
PF16792 Caud_bapl16_1st 238 14 8
PF16838 Caud_tail_N 204 120 95
PF18994 Prophage_tailD1 1,484 752 401
PF20195 DUF6558 226 165 106
PF20751 SP2_M 11,947 314 62
PF20752 SP2_C 1,832 105 14
PF20955 Caud_bapl16_4th 246 15 10
PF21424 DTP-pb9_A-dom_C 180 10 1
PF21425 DTP-pb9_A-dom_N 223 23 8
PF21683 GpP-like_1st 2,591 1,055 361
PF21821 Dit_like 3,408 1,404 653
CL0505 Pentapeptide 96,315 60,132 28,628 PF00805 Pentapeptide 73,149 46,679 22,785
PF01469 Pentapeptide_2 2,734 1,659 817
PF13576 Pentapeptide_3 4,386 3,390 1,938
PF13599 Pentapeptide_4 30,408 17,938 8,707
CL0506 Succ_CoA_synth 138,808 55,846 7,806 PF00549 Ligase_CoA 95,391 31,093 2,540
PF13607 Succ_CoA_lig 38,956 23,012 4,788
PF16114 Citrate_bind 7,106 2,487 458
PF19045 Ligase_CoA_2 15,838 9,897 2,030
CL0507 Fungal_trans 247,734 138,537 54,874 PF04082 Fungal_trans 179,061 98,856 37,969
PF11951 Fungal_trans_2 68,593 39,640 16,905
PF16846 Cep3 124 86 48
CL0508 YkuD 138,660 75,556 18,412 PF03734 YkuD 128,516 69,726 17,042
PF10908 Tlde1_dom 3,306 1,759 521
PF13645 YkuD_2 6,836 4,072 851
CL0509 RBP11-like 82,722 25,233 4,196 PF01193 RNA_pol_L 72,234 20,044 2,762
PF13656 RNA_pol_L_2 10,623 5,308 1,495
CL0511 Retroviral_zf 185,150 93,762 48,061 PF00098 zf-CCHC 155,039 75,759 39,602
PF12353 eIF3g 4,126 1,741 553
PF13696 zf-CCHC_2 6,299 2,907 1,012
PF13917 zf-CCHC_3 4,642 2,496 948
PF14392 zf-CCHC_4 8,650 7,578 5,362
PF14787 zf-CCHC_5 902 575 267
PF15288 zf-CCHC_6 3,452 1,896 516
PF16641 CLIP1_ZNF 3,775 1,807 401
PF21759 AIR2-like_ZnK4 118 74 28
CL0512 CRAL_TRIO 80,602 38,129 12,356 PF00650 CRAL_TRIO 54,665 27,735 10,268
PF13716 CRAL_TRIO_2 25,935 10,400 2,104
CL0513 LCCL-domain 11,793 4,743 1,532 PF03815 LCCL 9,872 3,715 1,121
PF08642 Rxt3 1,919 1,028 412
CL0515 LTXXQ-like 24,457 14,638 7,501 PF07813 LTXXQ 13,672 7,648 3,890
PF12875 DUF3826 819 485 125
PF13801 Metal_resist 9,590 6,338 3,592
PF16231 DUF4890 377 238 148
CL0516 ISP-domain 209,895 106,208 19,838 PF00355 Rieske 192,777 99,084 19,080
PF13806 Rieske_2 12,931 6,061 835
PF18465 Rieske_3 4,217 1,193 95
CL0517 MBOAT-like 63,159 33,824 9,611 PF03062 MBOAT 54,611 28,225 7,082
PF13813 MBOAT_2 8,546 5,599 2,532
CL0520 Keratin_assoc 6,089 3,794 1,569 PF01500 Keratin_B2 914 378 161
PF05287 PMG 1,408 705 184
PF13885 Keratin_B2_2 4,002 2,894 1,371
CL0521 GOLD-like 28,257 12,205 3,446 PF01105 EMP24_GP25L 25,221 11,147 3,110
PF13897 GOLD_2 3,034 1,058 338
CL0522 YbjQ-like 23,209 11,133 1,789 PF01906 YbjQ_1 21,692 10,748 1,692
PF11524 SeleniumBinding 20 12 6
PF16358 RcsF 1,494 373 91
CL0523 GAG-polyprotein 164,827 130,315 74,938 PF01021 TYA 308 65 47
PF03564 DUF1759 15,551 12,089 8,797
PF03732 Retrotrans_gag 69,084 54,883 30,037
PF13961 DUF4219 4,757 3,684 2,399
PF14223 Retrotran_gag_2 62,018 50,110 28,934
PF14244 Retrotran_gag_3 8,111 7,097 4,664
PF14893 PNMA 3,443 2,039 1,111
PF16297 DUF4939 2,645 1,786 1,006
PF17241 Retrotran_gag_4 136 111 93
PF19259 Ty3_capsid 4,986 3,707 2,489
CL0524 MPT63-MPB63 10,945 6,391 3,420 PF09167 DUF1942 1,014 489 111
PF11611 DUF4352 7,884 4,799 2,679
PF14263 DUF4354 194 86 50
PF16729 DUF5067 1,495 880 544
PF16781 DUF5068 356 142 50
CL0525 pap2 189,136 103,184 33,768 PF01569 PAP2 148,464 80,899 27,175
PF02681 DUF212 8,420 4,661 1,011
PF10261 FIT 3,014 1,705 574
PF14360 PAP2_C 8,087 3,645 1,273
PF14378 PAP2_3 20,936 12,187 3,873
PF17897 VCPO_N 278 212 79
CL0526 SUKH 42,139 22,867 9,310 PF02393 US22 1,926 664 302
PF07348 Syd 2,660 903 188
PF09346 SMI1_KNR4 25,299 14,604 6,597
PF14433 SUKH-3 2,477 1,336 469
PF14435 SUKH-4 3,431 2,277 658
PF14567 SUKH_5 2,675 1,098 461
PF14568 SUKH_6 3,674 2,113 986
CL0528 DUF1214 18,860 11,760 2,867 PF06742 DUF1214 16,918 10,543 2,221
PF06863 DUF1254 13,255 8,452 1,763
CL0529 FMN-dep-NRtase 173,646 95,653 18,862 PF00881 Nitroreductase 162,066 88,867 16,454
PF10229 MMADHC 2,230 1,093 415
PF13486 Dehalogenase 4,319 2,575 843
PF14512 TM1586_NiRdase 4,772 3,421 1,203
PF16690 MMACHC 1,226 508 212
CL0530 DNase_I-like 264,210 151,300 55,214 PF03372 Exo_endo_phos 234,530 129,781 43,043
PF14529 Exo_endo_phos_2 20,870 16,317 11,451
PF19580 Exo_endo_phos_3 8,842 5,607 1,789
CL0531 AMP-binding_C 499,286 266,514 56,778 PF13193 AMP-binding_C 476,701 254,755 55,605
PF14535 AMP-binding_C_2 22,584 11,760 1,179
CL0532 LIG 19,296 11,512 4,752 PF02221 E1_DerP2_DerF2 10,743 6,284 2,775
PF06477 DUF1091 3,986 3,073 1,589
PF14558 TRP_N 4,572 2,164 398
CL0533 PRTase-like 383,120 167,240 24,758 PF00156 Pribosyltran 270,218 126,954 19,776
PF11202 StiP 3,565 1,666 159
PF13793 Pribosyltran_N 68,026 24,026 2,664
PF14572 Pribosyl_synth 56,646 18,476 1,797
PF14681 UPRTase 46,399 17,527 2,223
PF15609 PRTase_2 3,535 1,725 318
PF15610 PRTase_3 585 299 99
CL0534 YjgF-like 162,803 80,298 11,065 PF01042 Ribonuc_L-PSP 131,396 64,194 9,515
PF07736 CM_1 6,687 3,625 375
PF09663 Amido_AtzD_TrzD 1,587 862 130
PF14588 YjgF_endoribonc 23,129 11,628 1,068
CL0535 CBM 16,045 7,498 2,242 PF02839 CBM_5_12 15,389 7,185 2,140
PF14600 CBM_5_12_2 835 382 127
CL0536 HEXAPEP 315,588 159,253 28,001 PF00132 Hexapep 260,096 135,508 24,384
PF07959 Fucokinase 3,802 1,653 540
PF12464 Mac 21,566 9,683 1,286
PF14602 Hexapep_2 74,850 37,153 7,512
PF16314 DUF4954 2,138 1,269 311
PF18776 Hexapep_loop 197 157 14
PF21711 DCTN5 5,559 2,418 642
CL0537 CCCH_zf 99,541 44,353 16,333 PF00642 zf-CCCH 72,081 31,367 12,140
PF14608 zf-CCCH_2 24,099 9,432 3,136
PF15663 zf-CCCH_3 3,418 1,477 505
PF16131 Torus 3,312 1,650 491
PF18044 zf-CCCH_4 17,475 8,252 3,281
PF18260 Nab2p_Zf1 58 34 4
PF18345 zf_CCCH_4 2,322 1,214 593
PF18384 zf_CCCH_5 2,660 878 154
PF18585 zf-CCCH_6 514 302 59
PF18586 zf-CCCH_7 3 4 3
PF18633 zf-CCCH_8 268 83 14
PF21457 zf-CCCH_2-like_3 142 94 25
PF21803 Nab2-zf4 346 244 62
CL0539 RNase_III 72,062 37,660 8,510 PF00636 Ribonuclease_3 24,201 12,574 4,053
PF11469 Ribonucleas_3_2 466 323 117
PF14622 Ribonucleas_3_3 49,378 25,647 4,743
PF20614 Mycovirus_RNAse 23 21 16
CL0540 GCP 21,391 9,907 3,843 PF04130 GCP_C_terminal 19,953 8,897 3,135
PF14609 GCP5-Mod21_N 934 479 123
PF17681 GCP_N_terminal 18,459 8,375 2,790
PF20685 GCP5-Mod21_C 47 40 32
CL0541 SH2-like 139,864 48,867 11,451 PF00017 SH2 130,034 44,722 10,525
PF02762 Cbl_N3 3,842 1,373 229
PF06236 MelC1 1,239 692 113
PF14633 SH2_2 4,745 2,081 584
CL0542 RAS_GEF_N 41,986 16,503 4,156 PF00618 RasGEF_N 38,214 14,953 3,686
PF14663 RasGEF_N_2 3,770 1,550 470
CL0543 Viral_gly_cn_dm 52,934 4,578 1,521 PF00869 Flavi_glycoprot 37,568 2,312 200
PF01561 Hanta_Gc_N 2,817 314 109
PF01589 Alpha_E1_glycop 5,091 238 59
PF03563 Bunya_G2 1,227 255 80
PF05748 Rubella_E1 2,963 61 20
PF06656 Tenui_PVC2 87 7 4
PF07245 Phlebovirus_G2 2,798 1,141 912
PF14884 EFF-AFF 375 250 137
CL0544 AcylCoA_ox_dh_N 441,481 184,925 20,111 PF02771 Acyl-CoA_dh_N 416,664 174,633 18,582
PF14749 Acyl-CoA_ox_N 7,688 3,249 775
PF18158 AidB_N 17,127 7,046 756
CL0545 APCOP-app_sub 38,002 17,832 4,641 PF02296 Alpha_adaptin_C 5,204 2,332 291
PF07386 DUF1499 9,913 6,578 2,385
PF09066 B2-adapt-app_C 7,104 2,875 503
PF09650 PHA_gran_rgn 4,661 2,436 626
PF12305 DUF3630 921 440 137
PF14806 Coatomer_b_Cpla 4,331 1,215 266
PF14807 AP4E_app_platf 943 424 137
PF16381 Coatomer_g_Cpla 4,917 1,533 296
CL0546 Hexosaminidase 50,924 28,737 8,063 PF02838 Glyco_hydro_20b 31,237 17,800 4,752
PF03648 Glyco_hydro_67N 4,642 3,068 845
PF05124 S_layer_C 1,457 1,163 656
PF12971 NAGLU_N 4,946 2,590 687
PF14845 Glycohydro_20b2 8,240 4,110 1,180
PF18229 GcnA_N 399 20 7
CL0547 GF_recep_C-rich 36,372 13,892 2,783 PF00219 IGFBP 15,672 5,323 1,051
PF00757 Furin-like 12,957 5,354 940
PF12190 amfpi-1 97 77 40
PF14843 GF_recep_IV 10,581 4,556 682
PF15913 Furin-like_2 3,921 1,477 424
CL0548 IHF-likeDNA-bdg 120,336 45,160 8,814 PF00216 Bac_DNA_binding 103,127 37,723 6,157
PF05261 Tra_M 843 142 50
PF14848 HU-DNA_bdg 1,136 546 242
PF14908 HU-CCDC81_euk_1 1,340 681 283
PF18174 HU-CCDC81_bac_1 3,547 2,431 933
PF18175 HU-CCDC81_bac_2 3,130 2,121 789
PF18289 HU-CCDC81_euk_2 1,992 1,120 371
PF18291 HU-HIG 9,418 3,023 959
CL0550 SRCR 39,328 22,344 8,949 PF00530 SRCR 32,923 19,793 8,410
PF09272 Hepsin-SRCR 621 215 41
PF15494 SRCR_2 5,782 2,347 508
CL0551 BCLiA 17,591 7,172 2,511 PF00452 Bcl-2 9,354 3,713 1,285
PF02180 BH4 1,955 524 97
PF06227 Poxv_Bcl-2-like 919 181 74
PF06393 BID 865 428 116
PF06489 Orthopox_A49R 73 13 6
PF10186 ATG14 5,720 2,627 931
PF11099 M11L 240 43 23
PF15286 Bcl-2_3 4 3 2
PF17649 VPS38 324 175 78
CL0552 Hect 76,701 34,713 10,078 PF00632 HECT 73,117 32,570 9,209
PF09814 HECT_2 3,582 2,143 869
CL0559 CBD9-like 39,447 26,574 11,421 PF03351 DOMON 12,236 6,620 3,043
PF06452 CBM9_1 17,266 13,738 6,177
PF09985 Glucodextran_C 1,895 1,365 571
PF16010 CDH-cyt 5,639 3,247 1,000
PF16011 CBM9_2 2,426 1,627 686
CL0560 Chalcone-like 12,272 7,279 2,434 PF02431 Chalcone 2,248 1,009 255
PF16035 Chalcone_2 2,359 1,324 414
PF16036 Chalcone_3 7,662 4,955 1,783
CL0561 LisH 29,050 10,660 3,145 PF08513 LisH 16,960 6,328 1,954
PF09398 FOP_dimer 3,079 1,233 412
PF16045 LisH_2 2,053 849 304
PF17814 LisH_TPL 5,512 1,783 415
PF21051 ARMC9_LisH 1,441 470 72
CL0562 Holin-V 2,074 1,232 326 PF06946 Phage_holin_5_1 482 288 94
PF16079 Phage_holin_5_2 1,590 944 236
CL0563 Holin-II 3,947 1,042 418 PF04971 Phage_holin_2_1 1,366 247 77
PF10746 Phage_holin_2_2 539 133 63
PF16080 Phage_holin_2_3 1,635 455 185
PF16082 Phage_holin_2_4 403 208 100
CL0564 Holin-III 5,738 1,518 546 PF05106 Phage_holin_3_1 3,093 732 220
PF16083 Phage_holin_3_3 1,745 615 306
PF16085 Phage_holin_3_5 897 171 20
CL0567 Phage_TACs 21,643 10,438 3,355 PF06222 Phage_TAC_1 631 166 41
PF06894 Phage_TAC_2 1,170 177 70
PF06896 Phage_TAC_3 456 152 89
PF08748 Phage_TAC_4 1,290 469 208
PF08890 Phage_TAC_5 1,792 1,007 339
PF09550 Phage_TAC_6 2,208 1,795 477
PF10109 Phage_TAC_7 6,486 2,691 1,050
PF10666 Phage_TAC_8 39 6 2
PF10876 Phage_TAC_9 142 57 23
PF10963 Phage_TAC_10 934 322 67
PF11836 Phage_TAC_11 2,956 2,215 395
PF12363 Phage_TAC_12 1,103 442 205
PF16459 Phage_TAC_13 604 264 73
PF16462 Phage_TAC_14 170 72 28
PF21822 Phage_TAC_15 1,651 607 291
CL0568 Man_lectin 12,601 6,957 3,121 PF00555 Endotoxin_M 872 371 137
PF01419 Jacalin 9,046 5,076 2,377
PF03762 VOMI 2,327 1,426 575
PF09131 Endotoxin_mid 164 30 12
PF16458 Beta-prism_lec 187 55 21
CL0570 PPP-I 75,761 39,899 11,272 PF02244 Propep_M14 10,490 4,987 1,549
PF05922 Inhibitor_I9 39,548 21,540 6,084
PF09286 Pro-kuma_activ 14,759 8,634 2,548
PF16470 S8_pro-domain 10,390 4,467 968
PF18237 Tk-SP_N-pro 107 65 20
PF18492 ORF_2_N 349 175 93
PF18513 Pro_sub2 71 21 5
PF21496 MIC5 40 11 10
CL0571 30K_movement 7,703 1,890 902 PF00803 3A 1,920 144 51
PF00845 Gemini_BL1 1,788 198 39
PF01107 MP 3,116 1,432 764
PF01573 Bromo_MP 545 63 23
PF03300 Tenui_NS4 85 11 7
PF03558 TBSV_P22 59 15 5
PF16505 Emaravirus_P4 183 27 13
CL0572 TIKI 44,900 27,741 9,395 PF01963 TraB_PrgY_gumN 24,521 14,112 5,170
PF04187 Cofac_haem_bdg 9,980 6,804 2,322
PF05139 Erythro_esteras 10,397 6,826 1,904
CL0573 KA1-like 36,736 14,761 3,915 PF02149 KA1 14,198 4,911 1,028
PF03822 NAF 10,680 3,804 690
PF14303 NAM-associated 4,055 2,871 1,710
PF16579 AdenylateSensor 4,305 1,307 229
PF21122 KA1_BRSK 3,537 1,902 281
CL0576 STARBD 14,258 7,333 2,765 PF03370 CBM_21 9,873 4,720 1,708
PF03423 CBM_25 1,134 662 218
PF16738 CBM26 1,845 1,165 604
PF16760 CBM53 1,519 871 286
CL0577 Paramyxovirin_C 638 60 31 PF01692 Paramyxo_C 258 12 5
PF02725 Paramyxo_NS_C 329 25 9
PF16821 C_Hendra 48 23 17
CL0578 AbiEI 8,213 5,382 2,025 PF09407 AbiEi_1 3,308 2,419 915
PF09952 AbiEi_2 2,278 1,639 783
PF11459 AbiEi_3 2,624 1,324 327
CL0580 YqgF 76,977 36,414 5,539 PF03652 RuvX 43,523 22,904 4,110
PF14639 YqgF 4,134 1,757 406
PF16921 Tex_YqgF 29,317 11,755 1,033
CL0582 TrkA_C 137,677 65,075 12,021 PF02080 TrkA_C 119,539 56,265 10,085
PF03493 BK_channel_a 13,590 6,345 1,112
PF06241 Castor_Poll_mid 4,041 2,189 706
PF21014 Slowpoke_C 7,173 3,527 353
CL0584 FF 13,718 5,506 1,594 PF01846 FF 11,930 4,987 1,491
PF16512 RhoGAP-FF1 2,620 599 120
CL0586 CTC1 1,683 735 327 PF15489 CTC1 1,255 522 230
PF15491 CTC1_2 426 213 97
CL0587 STAND_N 7,003 5,449 3,200 PF17107 SesA 1,892 1,535 932
PF17111 Helo_like_N 4,933 3,788 2,215
PF20701 HetE-N 175 126 59
CL0588 Ribos_L15p_L18e 63,803 27,585 3,462 PF00828 Ribosomal_L27A 56,144 24,252 2,759
PF17135 Ribosomal_L18 7,657 3,365 766
CL0589 KIX_like 9,647 5,335 1,873 PF02172 KIX 4,769 2,735 587
PF09606 Med15 1,661 771 300
PF16987 KIX_2 3,215 1,830 988
CL0590 OML_zippers 5,771 1,499 714 PF04728 LPP 2,512 264 87
PF09403 FadA 350 88 29
PF11839 Alanine_zipper 2,906 1,147 600
CL0591 TKC_like 290,271 130,631 11,079 PF02780 Transketolase_C 193,161 85,092 6,912
PF09363 XFP_C 12,744 5,693 356
PF16870 OxoGdeHyase_C 37,955 15,003 1,488
PF17147 PFOR_II 46,407 24,856 2,383
CL0592 beta_Roll 70,413 55,682 37,982 PF00353 HemolysinCabind 69,050 54,751 37,454
PF06594 HCBP_related 3,165 2,708 2,158
PF08548 Peptidase_M10_C 7,687 5,054 3,190
PF21735 RtxA_C 276 151 34
CL0593 G5 19,802 11,562 4,493 PF07501 G5 19,796 11,559 4,491
PF17041 SasG_E 125 91 56
CL0595 Fusion_gly 26,576 2,800 1,214 PF00523 Fusion_gly 17,247 782 183
PF01601 CoV_S2 7,634 824 111
PF12259 Baculo_F 1,519 1,145 885
PF17072 Spike_torovirin 172 49 35
CL0596 VPS23_C 15,459 6,514 2,006 PF03997 VPS28 3,682 1,487 406
PF07200 Mod_r 6,771 3,019 950
PF09454 Vps23_core 5,003 2,008 650
CL0597 Post-HMGL 41,691 15,354 1,167 PF02436 PYC_OADA 34,190 12,698 1,016
PF07836 DmpG_comm 7,499 2,656 151
CL0598 B_GA 10,339 5,692 3,812 PF01468 GA 1,434 849 603
PF02216 B 343 125 36
PF07554 FIVAR 6,277 3,619 2,471
PF07564 DUF1542 1,301 818 594
PF17573 GA-like 237 96 60
PF18449 Endotoxin_C2 1,337 593 336
CL0599 GH57_38_middle 35,992 20,000 5,021 PF09094 AmyA-A_glucT_m 2,098 1,604 523
PF09210 BE_C 5,260 3,077 512
PF09261 Alpha-mann_mid 28,631 15,319 3,986
CL0600 S15_NS1 141,034 23,465 2,254 PF00312 Ribosomal_S15 65,243 20,045 1,578
PF00458 WHEP-TRS 8,701 3,190 632
PF00600 Flu_NS1 58,123 177 17
PF02942 Flu_B_NS1 8,907 11 6
PF21643 T6SS_Tsi2-like 55 42 21
CL0601 Cob_adeno_trans 34,622 17,178 2,419 PF01923 Cob_adeno_trans 34,595 17,159 2,412
PF09155 DUF1940 25 19 7
CL0602 Kringle 33,337 13,352 3,843 PF00040 fn2 15,868 6,234 1,376
PF00051 Kringle 18,251 7,414 2,509
CL0603 AA_dh_N 265,247 118,153 13,745 PF00390 malic 66,605 25,319 2,178
PF00763 THF_DHG_CYH 61,958 27,770 3,069
PF02812 ELFV_dehydrog_N 69,946 29,971 2,466
PF08501 Shikimate_dh_N 64,573 33,894 5,904
PF09176 Mpt_N 2,161 1,200 129
CL0604 post-AAA 145,695 72,185 13,162 PF08542 Rep_fac_C 16,052 6,477 1,092
PF09115 DNApol3-delta_C 10,550 4,797 1,389
PF12002 MgsA_C 47,048 21,429 1,644
PF12169 DNA_pol3_gamma3 41,529 24,264 4,229
PF14840 DNA_pol3_delt_C 6,650 2,224 398
PF21694 DNA_pol3_delta_C 23,860 13,014 4,474
CL0605 ssDNA_NP_VP 16,760 3,899 1,142 PF00740 Parvo_coat 12,314 770 263
PF02305 Phage_F 3,846 2,921 719
PF02306 Phage_G 291 25 15
PF02336 Denso_VP4 313 188 148
CL0606 Phage_fibre 6,684 2,480 990 PF06715 Gp5_C 2,354 911 381
PF07212 Hyaluronidase_1 162 74 25
PF09089 gp12-short_mid 281 18 5
PF12219 End_tail_spike 91 25 17
PF18338 BppL_N 103 77 64
PF18715 Phage_spike 2,114 532 153
PF20744 gp37_trimer 442 267 125
PF21446 Gp34_C 1,180 613 240
CL0607 TNF_receptor 47,829 21,107 5,829 PF00020 TNFR_c6 17,809 8,523 2,976
PF07562 NCD3G 28,043 11,736 2,565
PF09256 BaffR-Tall_bind 263 133 23
PF09257 BCMA-Tall_bind 595 193 68
PF09305 TACI-CRD2 740 341 137
PF12191 stn_TNFRSF12A 343 157 69
PF18278 RANK_CRD_2 790 233 33
CL0608 Reductase_C 237,580 104,335 12,773 PF02852 Pyr_redox_dim 171,796 74,567 8,372
PF09242 FCSD-flav_bind 3,665 2,355 234
PF14721 AIF_C 2,958 1,190 286
PF14759 Reductase_C 27,121 14,034 2,178
PF18113 Rbx_binding 4,703 1,389 205
PF18267 Rubredoxin_C 25,510 10,150 1,365
PF21791 MDHAR3-like_C 1,820 650 137
CL0609 sPC4_like 29,434 12,507 3,368 PF02229 PC4 9,391 4,625 1,586
PF04686 SsgA 7,712 2,628 540
PF04845 PurA 4,255 1,355 369
PF08536 Whirly 1,190 633 251
PF08848 DUF1818 831 441 71
PF09387 MRP 1,735 423 74
PF11680 DUF3276 4,102 2,248 400
PF18228 CdiI_N 210 154 77
CL0611 Hexon 12,977 1,789 480 PF01065 Adeno_hexon 8,731 557 85
PF04451 Capsid_NCLDV 4,235 1,228 391
PF09018 Phage_Capsid_P3 8 4 4
CL0612 PHM_PNGase_F 13,753 7,964 3,423 PF01082 Cu2_monooxygen 8,168 3,884 1,625
PF03712 Cu2_monoox_C 10,162 5,477 2,363
PF09112 N-glycanase_N 1,623 988 252
PF09113 N-glycanase_C 2,900 1,984 704
CL0613 Terp_synthase 339,960 183,732 40,196 PF00348 polyprenyl_synt 122,904 62,567 12,314
PF00494 SQS_PSY 48,435 27,018 5,466
PF01040 UbiA 135,812 74,873 15,292
PF03936 Terpene_synth_C 15,127 8,563 3,241
PF06330 TRI5 1,694 1,084 453
PF07307 HEPPP_synt_1 1,728 850 311
PF19086 Terpene_syn_C_2 15,363 9,476 3,506
CL0614 L27 28,719 10,289 1,708 PF02828 L27 15,176 4,326 653
PF09045 L27_2 3,062 1,673 151
PF09058 L27_1 4,874 2,147 459
PF09060 L27_N 1,201 194 35
PF18031 UCH_C 5,433 2,108 431
CL0615 ALDC 30,101 15,416 4,477 PF03306 AAL_decarboxy 6,360 2,887 960
PF03479 PCC 21,536 11,557 3,190
PF08925 DUF1907 2,202 972 327
CL0616 SPOC 41,221 19,293 4,633 PF02735 Ku 27,151 13,487 2,706
PF07744 SPOC 12,191 5,017 1,647
PF11232 Med25 1,780 724 242
PF18636 Sld7_N 95 65 38
CL0617 Peroxidase 97,303 50,185 12,389 PF00141 peroxidase 67,382 34,131 6,511
PF03098 An_peroxidase 29,869 16,011 5,841
PF11895 Peroxidase_ext 1,191 795 145
CL0618 MCR 5,590 970 148 PF02240 MCR_gamma 663 223 27
PF02745 MCR_alpha_N 4,254 506 85
PF02783 MCR_beta_N 670 241 36
CL0619 Mog1p_PsbP 23,337 11,712 4,144 PF01789 PsbP 5,218 2,731 813
PF04603 Mog1 2,912 1,560 545
PF08786 DcrB 4,134 1,248 487
PF09449 DUF2020 435 276 71
PF10738 Lpp-LpqN 1,970 1,025 228
PF12712 DUF3805 361 105 36
PF14032 PknH_C 4,549 2,396 706
PF18702 DUF5642 1,079 563 106
PF18933 PsbP_2 1,588 1,186 876
PF20928 PsbP_C 5,271 2,672 739
CL0620 Antihemostatic 3,211 1,522 827 PF00713 Hirudin 35 15 6
PF02822 Antistasin 3,172 1,506 820
PF09065 Haemadin 1 1 1
CL0621 Colipase 4,592 1,904 501 PF01114 Colipase 597 288 38
PF02740 Colipase_C 665 317 43
PF06607 Prokineticin 2,045 935 289
PF21479 DIKK1-2-4_C-subdom2 1,778 565 111
PF21481 DIKK1-2-4_C-subdom1 1,856 636 157
CL0622 Acylphosphatase 86,770 48,014 11,029 PF00708 Acylphosphatase 45,529 27,501 6,276
PF04940 BLUF 10,344 6,689 2,686
PF06544 Prp3_C 7,038 2,984 878
PF17773 UPF0176_N 23,855 10,840 1,189
CL0623 SRP9_14 6,794 3,162 887 PF02290 SRP14 3,605 1,761 482
PF05486 SRP9-21 3,187 1,402 406
CL0625 eIF4e 18,133 8,389 2,802 PF01652 IF4E 15,691 6,995 2,245
PF03536 VRP3 357 89 46
PF08939 Bles03 2,082 1,305 511
CL0626 Levi_coat 398 95 39 PF01819 Levi_coat 394 92 36
PF09063 Phage_coat 2 3 3
CL0627 Antibiotic_NAT 11,907 6,628 1,674 PF02522 Antibiotic_NAT 7,596 4,822 1,543
PF04260 DUF436 4,309 1,806 131
CL0628 EspA_CesA 953 190 74 PF03433 EspA 894 180 68
PF11439 T3SchapCesA 57 10 6
CL0629 PLA2 22,136 10,619 4,027 PF00068 Phospholip_A2_1 8,979 4,743 1,443
PF05826 Phospholip_A2_2 3,719 2,157 1,062
PF06951 PLA2G12 2,654 1,105 426
PF08398 Phospholip_A2_4 4,376 1,170 598
PF09056 Phospholip_A2_3 2,403 1,445 504
CL0630 PSI 57,160 22,921 4,895 PF00088 Trefoil 9,645 5,292 1,780
PF01437 PSI 38,752 15,171 2,641
PF17205 PSI_integrin 8,761 2,460 476
CL0631 YgaC_TfoX-N 86,398 55,219 9,584 PF04237 YjbR 28,963 15,998 2,444
PF04993 TfoX_N 14,438 8,690 2,003
PF08818 DUF1801 32,477 23,997 3,675
PF09400 DUF2002 1,002 128 27
PF17648 Luciferase 2,126 1,289 385
PF18899 DUF5655 6,068 4,204 951
PF19694 DUF6194 1,328 926 142
CL0632 FERM_M 110,728 45,469 9,170 PF00373 FERM_M 81,741 32,465 5,884
PF00887 ACBP 21,585 10,511 2,929
PF18377 FERM_F2 5,220 1,829 160
PF18379 FERM_F1 5,012 1,787 175
PF21271 SNX17-31_F2_FERM 2,008 551 145
CL0633 NusB 76,517 39,541 7,806 PF01029 NusB 76,511 39,538 7,804
PF09185 DUF1948 4 3 2
CL0634 CheY-binding 8,535 4,120 802 PF07194 P2 5,822 3,448 732
PF09078 CheY-binding 2,711 672 70
CL0635 DmpA_ArgJ 186,503 101,893 18,127 PF01960 ArgJ 33,070 16,876 1,988
PF02738 MoCoBD_1 111,450 59,046 8,841
PF03576 Peptidase_S58 21,555 12,470 1,550
PF04734 Ceramidase_alk 12,209 7,666 2,717
PF20256 MoCoBD_2 113,198 60,205 9,427
CL0636 Leukocidin 4,493 1,735 415 PF07968 Leukocidin 1,327 234 125
PF09203 MspA 3,154 1,498 287
PF12563 Hemolysin_N 206 50 26
CL0637 KaiA_RbsU 2,595 1,397 331 PF07688 KaiA 796 423 87
PF08673 RsbU_N 1,797 974 244
CL0639 Rof 8,994 4,458 1,344 PF01868 RNase_P-MRP_p29 6,677 3,677 1,128
PF07073 ROF 2,315 781 216
CL0640 Colicin_D_E5 572 462 383 PF11429 Colicin_D 378 302 239
PF12106 Colicin_E5 192 160 145
CL0642 SOCS_box 32,813 10,134 2,716 PF07525 SOCS_box 31,973 9,761 2,623
PF17211 VHL_C 838 373 94
CL0643 YqbG 12,198 6,161 2,533 PF05135 Phage_connect_1 10,057 5,380 2,190
PF11436 DUF3199 221 93 24
PF11650 P22_Tail-4 680 162 77
PF17212 Tube 1,236 526 242
CL0644 Fz 43,925 16,410 4,741 PF01153 Glypican 8,140 3,333 1,092
PF01392 Fz 23,515 7,726 2,258
PF03024 Folate_rec 5,760 2,512 698
PF16414 NPC1_N 6,506 2,841 693
CL0645 Anti-sigma_N 57,083 37,591 17,265 PF03872 RseA_N 7,869 3,650 1,229
PF13490 zf-HC2 49,212 33,941 16,039
CL0646 T3SS 4,676 1,524 461 PF01893 UPF0058 1,663 658 133
PF07201 HrpJ 2,632 725 259
PF09025 T3SS_needle_reg 160 50 16
PF09059 TyeA 670 294 146
PF21439 MxiC_C 28 1 1
CL0647 FG_rpt 8,846 4,537 1,790 PF13634 Nucleoporin_FG 6,786 3,882 1,558
PF15967 Nucleoporin_FG2 2,108 695 256
CL0648 Aha1_BPI 40,068 19,721 7,181 PF01273 LBP_BPI_CETP 8,342 3,692 1,101
PF02886 LBP_BPI_CETP_C 8,514 3,963 1,322
PF06585 JHBP 7,884 5,584 2,794
PF07273 DUF1439 3,433 1,150 321
PF09229 Aha1_N 5,724 2,666 811
PF16984 Grp7_allergen 1,390 1,037 614
PF17047 SMP_LBD 9,313 3,862 840
PF18696 SMP_C2CD2L 1,885 577 114
CL0649 PseudoU_synth 375,645 195,477 37,803 PF00849 PseudoU_synth_2 223,017 113,398 19,888
PF01142 TruD 19,106 9,457 3,089
PF01416 PseudoU_synth_1 61,254 32,825 6,100
PF01509 TruB_N 55,777 29,716 5,256
PF08068 DKCLD 6,552 2,900 370
PF10105 DUF2344 10,218 6,519 2,064
PF16198 TruB_C_2 46,295 24,010 3,588
PF21238 Pus10_C 5,443 2,964 1,027
CL0650 AOC_barrel 24,672 14,064 4,220 PF03018 Dirigent 11,464 6,098 1,983
PF06351 Allene_ox_cyc 973 503 120
PF11528 DUF3224 3,609 2,339 614
PF11578 DUF3237 8,445 5,013 1,446
PF18678 AOC_like 176 111 61
CL0651 Mad2 20,093 8,935 3,086 PF02301 HORMA 10,450 4,981 1,703
PF06581 p31comet 1,043 469 170
PF07855 ATG101 3,472 1,470 532
PF10033 ATG13 4,901 1,911 657
PF18173 bacHORMA_2 222 106 24
CL0652 S24e_L23_L15e 66,059 23,742 2,570 PF00281 Ribosomal_L5 51,740 18,441 1,229
PF00827 Ribosomal_L15e 8,211 3,108 583
PF01251 Ribosomal_S7e 5,400 1,875 495
PF05162 Ribosomal_L41 704 318 263
CL0653 VCCI 767 123 60 PF02250 Orthopox_35kD 261 50 23
PF04490 Pox_T4_C 93 17 7
PF04491 Pox_T4_N 107 19 8
PF07190 CrmD_SECRET 393 53 28
CL0654 WYL 88,287 48,682 12,168 PF08863 YolD 4,599 2,486 924
PF10902 WYL_2 1,483 503 220
PF13280 WYL 82,037 45,609 10,978
PF18488 WYL_3 164 84 46
CL0655 PilP 18,507 11,318 4,506 PF04351 PilP 7,793 4,651 1,388
PF11356 T2SSC 7,570 4,478 1,997
PF16537 T2SSB 3,141 2,189 1,122
CL0656 VSA 5,029 3,731 578 PF02009 RIFIN 4,090 3,152 478
PF17410 Stevor 944 586 105
CL0658 OB_enterotoxin 2,864 859 320 PF01123 Stap_Strp_toxin 783 123 63
PF01376 Enterotoxin_b 138 9 5
PF02258 SLT_beta 292 17 8
PF02918 Pertussis_S2S3 211 14 10
PF06453 LT-IIB 13 6 3
PF09199 SSL_OB 470 126 29
PF09275 Pertus-S4-tox 9 2 2
PF09276 Pertus-S5-tox 10 2 2
PF18047 PatG_D 765 429 149
PF18065 PatG_C 881 525 182
CL0659 CAP 81,955 52,197 24,097 PF00188 CAP 81,551 51,895 23,864
PF17641 ASPRs 402 302 235
CL0660 SHOCT 56,529 32,741 10,416 PF05120 GvpG 2,714 1,501 287
PF06464 DMAP_binding 8,590 2,864 410
PF08044 DUF1707 14,093 8,601 2,178
PF09851 SHOCT 26,025 17,342 6,531
PF10832 YhfG 1,471 361 103
PF18495 VbhA 1,741 1,056 517
PF18822 CdvA 767 447 132
PF20612 SHOCT_2 1,122 572 264
CL0661 Gain 81,902 36,931 10,658 PF00791 ZU5 26,222 10,989 2,321
PF01825 GPS 40,595 18,661 5,612
PF04096 Nucleoporin2 6,258 3,076 1,117
PF06697 DUF1191 1,704 919 300
PF10577 FAM171A1-2-B_N 2,579 744 197
PF13553 FIIND 3,199 1,725 807
PF16489 GAIN 19,758 8,385 1,453
CL0662 Triple_barrel 33,855 17,687 6,400 PF04658 TAFII55_N 4,332 2,012 699
PF04801 RPC5 4,533 2,147 909
PF05132 RNA_pol_Rpc4 4,095 2,231 884
PF06870 RNA_pol_I_A49 3,691 2,087 797
PF08208 RNA_polI_A34 1,975 1,204 552
PF08615 RNase_H2_suC 3,136 2,065 907
PF12157 DUF3591 5,202 2,745 722
PF17683 TFIIF_beta_N 3,444 1,521 427
PF17745 Ydr279_N 3,440 1,677 504
CL0663 CNF1_YfiH 49,378 28,888 6,864 PF02578 Cu-oxidase_4 35,783 20,795 4,956
PF03975 CheD 13,410 7,990 1,840
PF05785 CNF1 160 94 63
PF17752 BLF1 21 9 5
CL0664 UB2H 96,998 40,583 5,117 PF14814 UB2H 6,962 2,428 450
PF17757 UvrB_inter 90,034 38,155 4,674
CL0665 BET 15,705 6,743 1,984 PF17035 BET 13,630 6,109 1,817
PF17793 AHD 2,073 634 167
CL0666 Vault 1,935 839 265 PF01505 Vault 1,758 712 188
PF17794 Vault_2 1,706 672 170
PF17795 Vault_3 1,656 646 149
PF17796 Vault_4 1,666 647 145
CL0667 Fer2_BFD 111,006 50,614 7,060 PF04324 Fer2_BFD 58,928 26,961 4,195
PF16901 DAO_C 38,050 16,952 2,115
PF17806 SO_alpha_A3 14,025 6,765 901
CL0668 Pre-PUA 19,371 8,557 1,921 PF09183 DUF1947 858 573 207
PF14810 TGT_C2 3,247 1,814 386
PF17126 RsmF_methylt_CI 4,320 1,980 300
PF17832 Pre-PUA 7,076 2,886 781
PF17833 UPF0113_N 3,865 1,306 256
CL0669 NOG1_N 10,149 4,961 1,650 PF13767 DUF4168 2,944 1,908 919
PF17835 NOG1_N 7,203 3,053 731
CL0670 4PPT 73,594 41,815 13,763 PF01648 ACPS 73,262 41,571 13,609
PF17837 4PPT_N 9,242 4,737 1,635
CL0671 AAA_lid 822,149 352,870 51,798 PF02151 UVR 99,665 43,903 5,936
PF08369 PCP_red 7,144 3,521 532
PF08406 CbbQ_C 8,199 3,553 322
PF09336 Vps4_C 18,946 6,617 1,732
PF10431 ClpB_D2-small 171,386 62,833 7,312
PF12213 Dpoe2NT 1,555 595 176
PF13335 Mg_chelatase_C 38,670 20,683 2,503
PF14629 ORC4_C 3,513 1,782 616
PF16193 AAA_assoc_2 45,590 20,688 1,260
PF17855 MCM_lid 32,673 12,981 3,250
PF17856 TIP49_C 8,226 2,224 393
PF17857 AAA_lid_1 18,751 11,132 2,887
PF17862 AAA_lid_3 183,734 72,528 12,281
PF17863 AAA_lid_2 88,724 44,006 3,445
PF17864 AAA_lid_4 43,182 16,536 544
PF17865 AAA_lid_5 3,841 2,526 749
PF17866 AAA_lid_6 14,621 7,577 1,767
PF17867 AAA_lid_7 4,692 3,040 1,121
PF17868 AAA_lid_8 5,029 1,902 525
PF17871 AAA_lid_9 114,488 42,688 4,345
PF17872 AAA_lid_10 5,533 2,650 757
PF18198 AAA_lid_11 25,959 14,505 3,718
PF20436 LonB_AAA-LID 10,609 5,618 1,091
PF21108 MDN1_4th 2,624 1,657 441
PF21328 Gp44_lid 978 290 62
PF21376 TOR1A_C 4,520 1,720 392
PF21396 AAA_lid_12 11 3 1
PF21450 RIF2_lid 18 6 1
PF21499 DYN1_lid 16 8 3
PF21500 HolB_lid 1,644 316 38
PF21639 ORC5_lid 3,174 1,369 361
CL0672 p35 125,636 71,098 21,642 PF02331 P35 44 22 13
PF05268 GP38 407 155 90
PF09972 DUF2207 10,536 6,921 3,240
PF12810 Gly_rich 3,688 2,555 1,357
PF12969 DUF3857 11,451 8,500 3,920
PF14415 DUF4424 1,851 820 351
PF17899 Peptidase_M61_N 12,236 7,680 1,636
PF17900 Peptidase_M1_N 82,700 42,386 9,435
PF21722 Gly_rich_2 2,717 2,062 1,604
CL0673 GYF 26,356 15,190 6,452 PF02213 GYF 11,365 5,619 2,039
PF14237 GYF_2 14,993 9,572 4,414
CL0674 Triple_B_spiral 1,659 242 127 PF00608 Adeno_shaft 1,447 200 95
PF06536 Av_adeno_fibre 304 59 44
CL0676 SLATT 8,816 5,780 2,808 PF14015 DUF4231 2,188 1,612 891
PF18142 SLATT_fungal 1,774 1,162 531
PF18159 S_4TM 592 437 257
PF18160 SLATT_5 618 509 310
PF18169 SLATT_6 225 147 64
PF18181 SLATT_1 1,523 999 487
PF18183 SLATT_2 1,224 545 138
PF18184 SLATT_3 921 513 171
PF18186 SLATT_4 934 587 267
CL0677 GHMP_C 124,598 65,038 12,943 PF08544 GHMP_kinases_C 114,160 59,664 12,036
PF09109 Xol-1_GHMP-like 24 18 14
PF18376 MDD_C 10,383 5,338 884
PF21433 M3K_C 32 23 14
CL0678 CLIP 5,247 3,463 1,725 PF12032 CLIP 3,142 2,122 1,091
PF18322 CLIP_1 1,484 959 446
PF18398 CLIP_SPH_mas 366 228 96
PF18399 CLIP_SPH_Scar 311 193 116
CL0679 TACC 6,886 2,662 903 PF05010 TACC_C 5,832 2,128 754
PF12709 Fungal_TACC 1,052 534 149
CL0680 WW 89,125 41,611 12,093 PF00397 WW 88,178 41,241 12,069
PF18507 WW_1 56 35 4
PF20625 WW_USP8 888 336 20
CL0681 HAMP 517,788 272,032 90,062 PF00672 HAMP 513,656 269,334 88,838
PF18575 HAMP_N3 2,827 1,093 395
PF18947 HAMP_2 15,727 8,413 3,027
CL0682 MBG 7,469 6,430 5,039 PF17883 MBG 510 351 261
PF18657 YDG 2,693 2,384 1,840
PF18676 MBG_2 4,838 4,211 3,318
PF18887 MBG_3 879 784 716
CL0683 MICOS 2,433 1,241 422 PF15884 QIL1 1,343 655 236
PF17050 AIM5 1,088 586 186
CL0684 NFACT_RNA-bind 27,585 15,112 4,011 PF05670 NFACT-R_1 23,243 12,626 3,534
PF18297 NFACT-R_2 12,823 6,701 1,566
CL0685 AmpE_CobD-like 27,037 13,687 2,253 PF03186 CobD_Cbib 23,559 12,657 2,008
PF17113 AmpE 7,048 2,376 512
CL0686 aG_PT 1,701 1,148 458 PF18723 HMUDK_hel 1,220 862 325
PF18724 ADDT 228 78 47
PF18746 aGPT-Pplase3 250 209 87
CL0687 Zn_chelatase 9,185 7,266 4,200 PF18717 CxC4 1,545 703 349
PF18718 CxC5 1,038 909 578
PF18721 CxC6 879 799 456
PF18802 CxC1 1,570 1,197 744
PF18803 CxC2 4,291 3,831 2,093
PF18804 CxC3 439 346 263
CL0688 BECR 6,526 4,231 2,280 PF12033 DUF3519 1,404 939 258
PF18809 PBECR1 813 587 382
PF18810 PBECR2 1,306 972 510
PF18812 PBECR3 1,312 888 499
PF18813 PBECR4 1,249 672 423
PF18814 PBECR5 131 103 93
PF18819 MuF_C 784 490 408
CL0689 TSP3 42,198 27,979 16,522 PF02412 TSP_3 22,856 13,409 7,049
PF03495 Binary_toxB 545 297 187
PF14092 DUF4270 4,926 3,508 1,364
PF18884 TSP3_bac 14,280 11,133 8,267
CL0690 TrbC_VirB2 35,859 18,733 9,242 PF04956 TrbC 11,496 4,703 1,140
PF12750 Maff2 3,045 475 93
PF12963 DUF3852 412 195 35
PF13572 DUF4134 4,323 1,198 186
PF16943 T4SS_CagC 726 62 20
PF18895 T4SS_pilin 15,854 12,103 7,786
CL0691 Phage_tail_2 19,571 9,535 3,791 PF06141 Phage_tail_U 1,272 210 73
PF06891 P2_Phage_GpR 4,016 1,232 351
PF08873 Phage_Mu_Gp37 846 473 201
PF09646 Gp37 835 292 137
PF11367 DUF3168 6,268 4,014 1,452
PF12691 Minor_capsid_3 1,545 937 400
PF13554 DUF4128 2,082 947 431
PF16724 T4-gp15_tss 1,157 450 199
PF16807 DUF5072 121 59 19
PF20765 DUF6838 1,419 921 528
CL0692 TSP1 88,384 38,293 12,358 PF00090 TSP_1 70,494 30,238 9,468
PF19028 TSP1_spondin 10,857 4,818 1,691
PF19030 TSP1_ADAMTS 31,822 14,664 3,414
PF19035 TSP1_CCN 7,070 2,411 398
CL0693 Cas9_lobe 2,376 1,676 756 PF16592 Cas9_REC 1,122 706 334
PF18470 Cas9_a 1,252 971 430
CL0694 Choline_binding 19,997 9,058 5,080 PF01473 Choline_bind_1 14,189 6,233 3,519
PF19085 Choline_bind_2 3,568 1,635 1,024
PF19127 Choline_bind_3 15,501 6,852 3,694
PF21540 Choline_bind_4 473 319 265
CL0695 EndoU 13,185 4,298 2,067 PF09412 XendoU 4,187 2,272 876
PF14436 EndoU_bacteria 2,241 1,587 1,096
PF19215 CoV_NSP15_C 6,754 439 95
CL0696 Vmethyltransf 9,755 1,862 892 PF01660 Vmethyltransf 8,993 1,622 722
PF19222 Noda_Vmethyltr 557 175 124
PF19223 Chropara_Vmeth 202 65 46
CL0697 SDH_beta 88,340 38,988 6,216 PF03315 SDH_beta 32,200 10,859 884
PF19304 PGDH_inter 22,540 9,252 1,007
PF19305 MmgE_PrpD_C 33,597 18,877 4,325
CL0698 TrbL 18,893 6,920 2,417 PF04610 TrbL 14,508 5,715 2,010
PF19478 TrbL_2 2,784 409 94
PF19511 TrbL_5 417 184 46
PF19590 TrbL_3 294 154 43
PF19597 TrbL_4 885 462 235
CL0700 ArdcN 20,663 9,900 3,628 PF08401 ArdcN 15,177 7,013 2,614
PF10403 BHD_1 5,144 2,712 925
PF10404 BHD_2 4,383 2,218 676
PF20054 Tc-38 303 152 75
CL0701 NAD_kinase_C 134,505 67,566 15,072 PF00609 DAGK_acc 22,671 9,762 1,890
PF19279 YegS_C 49,872 28,022 7,858
PF19280 CERK_C 3,201 1,364 342
PF20143 NAD_kinase_C 58,758 28,422 4,986
CL0702 UIM 14,421 5,381 1,596 PF02809 UIM 13,594 5,083 1,528
PF18282 RAP80_UIM 825 298 69
CL0703 YtcA 9,208 2,798 611 PF07869 DUF1656 8,204 2,253 388
PF17090 Ytca 1,002 545 223
CL0704 HMA 180,569 95,987 20,883 PF00403 HMA 162,182 86,120 18,629
PF19991 HMA_2 3,095 1,897 954
PF21645 FakA-like_M 15,306 7,981 1,306
CL0705 VBS-like 33,873 11,866 2,992 PF01044 Vinculin 12,517 3,884 1,038
PF01608 I_LWEQ 9,907 3,897 660
PF05482 Serendipity_A 272 161 65
PF06840 PDC10_C 1,743 431 124
PF08913 VBS 4,604 1,798 183
PF09141 Talin_middle 4,173 1,632 223
PF12026 CAS_C 4,923 1,309 289
PF13324 GCIP_N 2,921 1,502 526
PF16515 HIP1_clath_bdg 2,594 970 94
PF20936 GCIP_C 1,653 780 243
PF21692 Talin_R4 4,642 1,846 246
CL0706 EMC6 8,301 3,838 1,204 PF07019 EMC6 5,073 2,283 751
PF08690 GET2 1,309 750 231
PF14963 Get2_like 939 266 89
PF19094 EMC6_arch 976 539 134
CL0707 Saposin_like 12,430 5,996 2,156 PF02199 SapA 3,982 1,678 553
PF03489 SapB_2 8,073 3,869 1,449
PF05184 SapB_1 7,248 3,336 1,222
PF20145 ARMET_N 1,885 829 203
PF20825 Saposin 951 400 105
CL0708 Polo-box 8,313 3,323 1,100 PF00659 POLO_box 5,600 2,136 622
PF15016 DUF4520 645 312 132
PF15025 DUF4524 727 366 155
PF18190 Plk4_PB1 1,721 644 216
PF18409 Plk4_PB2 1,692 620 202
PF18531 Polo_box_2 29 24 13
PF18544 Polo_box_3 75 49 24
CL0709 STING 1,959 1,015 409 PF15009 TMEM173 1,686 813 290
PF20300 prok_STING 271 202 119
CL0710 YeeE 43,610 26,214 3,529 PF04143 Sulf_transp 33,888 20,460 2,936
PF20398 DUF6691 10,090 6,078 755
CL0713 Acyl-CoA_desat 188,233 96,409 18,787 PF00487 FA_desaturase 111,566 55,427 10,087
PF04116 FA_hydroxylase 72,114 39,342 8,113
PF10520 Lipid_desat 4,553 1,643 590
CL0714 COX1-like 1,816,337 183,582 29,637 PF00115 COX1 1,805,086 176,739 27,793
PF05940 NnrS 9,458 6,021 1,657
PF11070 DUF2871 1,791 823 191
CL0715 Nckap1_CYFIP1-2 12,000 3,848 1,455 PF05994 FragX_IP 4,656 1,457 560
PF09735 Nckap1 5,288 1,630 547
PF14745 WASH-4_N 2,054 762 349
CL0716 Aquaporin-like 113,680 50,344 10,598 PF00230 MIP 86,155 38,889 8,385
PF01226 Form_Nir_trans 24,401 9,964 1,873
PF10136 SpecificRecomb 3,121 1,491 340
CL0717 YbaB 43,430 20,274 3,562 PF02575 YbaB_DNA_bd 43,168 20,190 3,551
PF10921 DUF2710 260 84 11
CL0718 Perilipin_sf 7,152 3,288 989 PF03036 Perilipin 6,453 2,908 818
PF17316 Perilipin_2 697 381 172
CL0719 Moesin_tail 9,361 2,025 388 PF00769 ERM_C 8,729 1,655 293
PF20491 Ermin 631 371 96
CL0720 Lag3_N 1,716 923 289 PF03310 Cauli_DNA-bind 117 39 22
PF09596 MamL-1 1,533 833 229
PF11498 Activator_LAG-3 63 51 38
CL0721 LAMP 7,771 3,464 1,003 PF01299 Lamp 5,285 2,341 709
PF05827 VAS1_LD 2,484 1,123 294
CL0722 SDH_alpha 74,630 33,724 6,104 PF03313 SDH_alpha 39,634 13,987 1,408
PF03972 MmgE_PrpD_N 34,994 19,737 4,696
CL0723 TRADD-N 4,230 1,657 547 PF09034 TRADD_N 811 213 35
PF13820 NCOA6_TRADD-N 1,832 670 206
PF20694 TRADD-like_N 1,586 776 314
CL0724 Kinetochore 12,815 6,464 2,372 PF05557 MAD 4,038 1,916 739
PF08234 Spindle_Spc25 3,282 1,552 598
PF08286 Spc24 2,058 1,056 391
PF09496 CENP-O 2,154 1,195 377
PF12539 Csm1 1,278 745 267
CL0725 Apolipoprotein 7,486 3,498 1,122 PF01442 Apolipoprotein 5,678 2,533 786
PF04691 ApoC-I 366 206 77
PF04711 ApoA-II 407 176 58
PF05355 Apo-CII 363 207 60
PF05778 Apo-CIII 398 191 45
PF07464 ApoLp-III 270 187 98
CL0726 Resistin 1,295 595 148 PF06954 Resistin 497 256 98
PF18459 PCSK9_C1 787 334 48
PF18463 PCSK9_C3 731 294 31
PF18464 PCSK9_C2 561 223 18
CL0727 Nucleosidase 49,812 25,456 6,112 PF01156 IU_nuc_hydro 46,021 22,885 5,495
PF07632 Sde182_NH-like 3,790 2,572 619
CL0728 Cas2 35,139 21,630 4,503 PF09707 Cas_Cas2CT1978 3,301 1,902 288
PF09827 CRISPR_Cas2 16,284 10,581 2,047
PF20229 ChrB_N 3,387 2,144 406
PF20803 PaaX_M 12,163 7,003 1,765
CL0729 Kre28-like_sf 1,834 915 307 PF15556 Zwint 410 174 39
PF17097 Kre28 55 41 22
PF20882 Sos7 1,353 693 239
PF20883 Kbp-5 12 7 7
CL0730 IL8 23,941 11,978 3,827 PF00048 IL8 23,473 11,818 3,761
PF05259 Herpes_UL1 218 48 28
PF20902 CXCL16 247 112 38
CL0731 SPOCS 6,357 3,615 1,437 PF10628 CotE 1,533 637 87
PF12673 SipL 3,095 1,951 918
PF18166 pP_pnuc_2 287 217 135
PF20918 SPOCS_spoVID-N 1,438 810 297
CL0732 RMP1-like 3,019 1,750 790 PF14780 NEPRO_N 2,040 1,115 493
PF20945 RMP1 977 635 299
CL0733 Ribosomal_L25 88,968 45,100 7,221 PF01386 Ribosomal_L25p 40,044 21,456 4,193
PF03562 MltA 13,221 6,634 1,248
PF03950 tRNA-synt_1c_C 34,852 16,420 1,474
PF20974 tRNA-synt_1c_C2 33,582 15,751 1,488
CL0734 Rpp14-Pop5-like 7,932 4,588 1,765 PF01900 RNase_P_Rpp14 6,733 3,838 1,462
PF20976 Pop8 1,197 752 318
CL0735 GatC-like 39,296 19,822 3,667 PF02686 GatC 38,226 19,181 3,438
PF20977 GatF 165 126 89
PF20978 Gta3 902 517 152
CL0736 Get5_C_sf 790 343 153 PF17840 Tugs 726 297 133
PF18514 Get5_C 62 46 20
CL0737 Mtd 4,375 2,310 1,052 PF18454 Mtd_N 1,299 883 633
PF20010 Collagen_trimer 3,074 1,427 419
CL0738 Arg_repressor_C 34,957 14,926 2,099 PF02863 Arg_repressor_C 19,216 7,104 1,096
PF08712 Nfu_N 15,739 7,822 1,003
CL0740 GCV_T_C 264,426 91,462 11,648 PF03143 GTP_EFTU_D3 121,630 24,494 3,447
PF08669 GCV_T_C 83,133 40,309 4,817
PF09173 eIF2_C 7,385 2,737 379
PF20258 tRNA_Me_trans_C 48,081 22,564 2,797
PF21110 GlxA 1,241 497 81
PF21130 YgfZ_barrel 2,950 862 127
CL0741 RGM 31,771 18,234 7,521 PF00094 VWD 28,746 17,249 7,252
PF06534 RGM_C 3,035 995 275
CL0742 PTS_IIA-like 5,517 2,546 678 PF03829 PTSIIA_gutA 3,551 1,236 298
PF04027 DUF371 1,964 1,310 380
CL0743 Spectrin 61,469 24,877 6,354 PF00435 Spectrin 51,878 21,095 5,457
PF02970 TBCA 3,712 1,942 614
PF18373 Spectrin_2 9,016 3,032 422
PF21019 Spectrin_3 7,207 2,418 399
PF21020 Spectrin_4 9,649 2,839 525
PF21097 SR_plectin_7 9,004 2,980 445
CL0745 MIT 29,936 11,536 2,967 PF04212 MIT 14,962 5,461 1,513
PF12063 ATG1-like_MIT1 4,116 1,704 281
PF12513 SUV3_C 5,690 2,599 694
PF17169 NRBF2_MIT 1,212 412 115
PF18572 T6PP_N 493 300 95
PF21126 KATNA1_MIT 2,897 800 191
PF21127 ATG1-like_MIT2 4,499 1,880 324
CL0746 AFF4_CHD 4,934 2,045 506 PF18876 AFF4_CHD 4,689 1,925 466
PF21204 Ebp1_C 243 120 40
CL0747 THUMP 54,085 23,567 5,004 PF02926 THUMP 47,336 21,610 4,587
PF21237 Pus10_N_euk 1,996 844 310
PF21239 RLMM_N 4,750 1,113 107
CL0748 DNA_prim_N 49,495 26,176 6,492 PF08275 DNAG_N 48,798 25,904 6,406
PF21268 Helic-prim_T7_N 695 272 86
CL0749 GH127_M 39,909 24,463 5,710 PF03633 Glyco_hydro_65C 17,569 9,686 1,749
PF17390 Bac_rhamnosid_C 21,541 14,357 3,875
PF21270 SOGP_4th 796 420 86
CL0750 ADAM_CR_sf 54,889 23,656 4,953 PF08516 ADAM_CR 20,855 8,566 1,614
PF16698 ADAM17_MPD 2,230 706 165
PF17771 ADAMTS_CR_2 21,166 9,805 2,041
PF19236 ADAMTS_CR_3 24,429 10,688 1,675
PF21299 ADAM10_Cys-rich 3,163 1,173 323
CL0751 Secretin_N0 95,485 53,360 21,643 PF07660 STN 39,304 19,159 6,685
PF10671 TcpQ 2,843 1,274 666
PF16344 FecR_C 36,522 24,011 11,802
PF16816 DotD 1,131 466 220
PF21304 T3S_SPI-1_N0 1,720 496 147
PF21305 type_II_gspD_N0 13,977 7,999 2,389
CL0752 PsbQ-like 4,679 2,408 673 PF05757 PsbQ 2,035 1,018 289
PF16785 SMBP 748 509 194
PF21329 CYP38_PsbQ-like 1,893 881 190
CL0753 ATPD-E_C 33,909 9,375 1,271 PF00401 ATP-synt_DE 31,760 8,598 1,120
PF21334 ATPD_C_fung 1,126 412 75
PF21335 ATPD_C_metazoa 1,020 365 77
CL0754 PGM_I-III 149,756 69,376 10,122 PF02878 PGM_PMM_I 142,866 64,983 7,914
PF02879 PGM_PMM_II 134,610 60,904 6,329
PF02880 PGM_PMM_III 134,897 61,271 6,659
PF21404 AMG1_III 4,301 1,727 416
PF21405 AMG1_II 3,764 1,391 255
CL0755 SASP 13,270 5,397 1,174 PF04259 SASP_gamma 1,208 503 160
PF08175 SspO 670 202 21
PF08176 SspK 695 228 26
PF08177 SspN 634 197 17
PF08179 SspP 1,020 395 79
PF09575 Spore_SspJ 77 21 10
PF13081 DUF3941 254 47 16
PF13213 DUF4021 290 57 21
PF13215 DUF4023 591 263 62
PF13217 DUF4025 709 343 132
PF14115 YuzL 913 251 44
PF14139 YpzG 589 224 45
PF14140 YpzI 594 194 14
PF14151 YfhD 1,087 526 137
PF14152 YfhE 710 333 79
PF17227 DUF5302 1,870 994 192
PF17444 YhdX 52 12 5
PF19756 DUF6243 912 444 56
PF19767 DUF6254 309 114 34
PF19907 DUF6380 66 49 24
CL0756 GMC 2,686 855 217 PF02063 MARCKS 1,201 503 111
PF05466 BASP1 771 216 83
PF06614 Neuromodulin 711 136 23
CL0757 TRAP 3,983 1,739 587 PF05083 LST1 278 147 56
PF11770 GAPT 197 100 48
PF15050 SCIMP 255 132 54
PF15234 LAT 345 127 42
PF15330 SIT 1,033 459 136
PF15332 LIME1 529 268 95
PF15347 PAG 723 234 53
PF15681 LAX 218 79 23
PF15703 LAT2 396 195 81
CL0758 L31 49,927 18,210 1,496 PF01197 Ribosomal_L31 47,583 16,907 1,132
PF09776 Mitoc_L55 1,185 675 216
PF21492 bL31_N 1,156 629 151
CL0759 Nop_N_sf 8,729 3,627 665 PF08156 NOP5NT 7,925 3,104 533
PF21572 Nop5_56-rel_N_Arc 762 506 129
PF21667 Nop5_N 39 17 3
CL0760 RBG 31,386 17,216 6,227 PF10293 DUF2405 1,663 959 324
PF10305 Fmp27_SW 1,596 902 282
PF10344 FMP27-BLTP2_N 1,787 758 173
PF10347 Fmp27_GFWDK 3,396 1,769 585
PF10351 FMP27-BLTP2_C 4,296 2,262 814
PF10359 Fmp27_WPPW 1,698 984 344
PF10479 BLTP1_C 2,357 1,185 334
PF12624 Chorein_N 18,290 9,677 2,944
PF13329 ATG2_CAD 3,076 1,662 417
PF16908 VPS13_ext_chorein 10,212 5,813 1,976
PF16910 VPS13_mid_rpt 8,942 4,812 1,271
PF20413 BLTP1_N 3,984 2,249 763
PF21675 BLTP2_RBG-6 1,536 724 251
PF21676 Atg2_N 1,011 510 158
PF21677 BLTP1_mid 1,709 848 178
PF21678 Csf1_mid_RBG 1,233 679 190
CL0761 ABC_sf 181 28 24 PF21707 ABC_AB 158 17 14
PF21709 ABC_C 21 11 10
CL0763 GpW_gp25-like 54,599 23,075 5,171 PF04965 GPW_gp25 23,246 10,266 2,416
PF10934 DUF2634 2,469 1,357 508
PF17482 Phage_sheath_1C 17,974 8,504 1,912
PF18945 VipB_2 10,909 2,953 347
CL0764 PHP14-like 38,127 15,940 2,093 PF02503 PP_kinase 35,788 14,848 1,620
PF05005 Ocnus 2,337 1,092 473
CL0765 PAC 6,312 3,443 1,287 PF10178 PAC3 2,049 945 360
PF16093 PAC4 2,775 1,572 546
PF21758 PAC_bac 1,485 926 381
CL0766 NCPF 9,297 5,217 1,273 PF07209 DUF1415 4,863 2,788 619
PF08892 YqcI_YcgG 3,626 1,897 462
PF21780 DUF6875 805 532 192
CL0767 MXAN_049 4,778 3,117 1,411 PF07791 DUF1629 4,165 2,726 1,286
PF09535 Gmx_para_CXXCG 447 317 90
PF15570 Imm43 163 74 41
CL0768 DUF960 2,336 1,104 406 PF06124 DUF960 1,496 529 176
PF21781 DUF6876 838 575 230
CL0769 SsdA_imm 3,292 2,289 504 PF14423 Imm5 348 207 110
PF21805 Imm5_like 2,942 2,082 394
CL0770 GH84_C 1,925 953 241 PF21774 NagJ_C 1,225 685 148
PF21809 Glyco_hydro_84_hel 699 278 101
CL0771 YaaA-like 24,545 11,895 2,125 PF03883 H2O2_YaaD 22,218 10,462 1,450
PF21818 DUF6884 2,325 1,433 675

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