EFI - Precomputed Enzyme Similarity Tool

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stage 1

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Option A: Generate data set of close relatives via InterProScan. Enter only protein sequence. Do not enter any fasta header information. (Max sequence length 65535)



Option B: Generate data set using Pfam IDs


Database Release Interpro 50

Pfam Identifier Description Number of Sequences
Beta/Gamma crystallin 219
Fructose-1 346
Cell-cycle control medial ring component 186
Uncharacterised protein family (UPF0093) 4568
DpnD/PcfM-like protein 638
Protein of unknown function (DUF2723) 1015
Replication initiator protein A (RepA) N-terminus 6109
TraH_2 77
NADH:ubiquinone oxidoreductase 195
Pilus biogenesis CpaD protein (pilus_cpaD) 600
nsp9 replicase 1236
YrhK-like protein 644
Secreted protein acidic and rich in cysteine Ca binding region 1191
C-terminal domain on CstA (DUF4161) 16003
NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) 193
Toxin in Odyssella and Amoebophilus 3
Cold shock protein DEAD box A 3665
Protein of unknown function (DUF1014) 772
Phosphotyrosine interaction domain (PTB/PID) 365
Human adenovirus early E3A glycoprotein 95
CB1 cannabinoid receptor-interacting protein 1 153
Domain of unknown function (DUF3821) 38
Protein of unknown function (DUF2605) 123
Prolamin-like 899
Translocon-associated protein (TRAP) 656
Repair protein Rad1/Rec1/Rad17 762
Prenyltransferase-like 2294
F-112 protein 4
FAD binding domain 70347
Herpesvirus pp38 phosphoprotein 37
F-box associated 2501
UPF0489 domain 602
Protein of unknown function (DUF3915) 221
Putative heavy-metal-binding 11675
Protein of unknown function 3035
SWIB/MDM2 domain 3393
Adenosine-deaminase (editase) domain 1465
Putative FMN-binding domain 4386
HlyD family secretion protein 84974
Filoviridae VP35 154
Domain of unknown function (DUF4358) 719
ST7 protein 563
Shal-type voltage-gated potassium channels 352
Enterobacterial protein of unknown function (DUF957) 3967
Peptidase C39 family 13434
Domain of unknown function (DUF4143) 12822
Protein of unknown function (DUF3637) 90
Complex 1 protein (LYR family) 3916
Rabaptin-like protein 908
Uncharacterized protein conserved in bacteria (DUF2328) 864
Domain of unknown function (DUF4420) 461
Domain of unknown function (DUF4082) 211
Glycine cleavage T-protein C-terminal barrel domain 27214
gpW 3422
Protein of unknown function (DUF2530) 1952
GCN5-related N-acetyl-transferase 13384
piRNA pathway germ-plasm component 251
DIX domain 1020
Protein of unknown function (DUF2567) 1940
Pyruvate ferredoxin/flavodoxin oxidoreductase 24363
Nucleoside transporter 2047
Myoactive tetradecapeptides family 2
LAGLIDADG DNA endonuclease family 591
Spermatogenesis-associated 139
CfrBI restriction endonuclease 224
Trypanosomal VSG domain 2217
YozD-like protein 349
XLF (XRCC4-like factor) 437
DVL family 421
Poxvirus protein I5 61
Protein of unknown function (DUF1064) 4130
YesK-like protein 424
Domain of unknown function (DUF4331) 419
C3HC zinc finger-like 707
Protein of unknown function DUF2625 684
Protein of unknown function (DUF4241) 549
VEGF heparin-binding domain 246
Methylamine dehydrogenase heavy chain (MADH) 207
Alanine dehydrogenase/PNT 27673
ArsC family 39271
Ribosomal protein S2 25492
Translocon-associated protein 233
Domain of unknown function (DUF4594) 210
AAA-ATPase Vps4-associated protein 1 350
NUMOD4 motif 1535
FIST C domain 6283
VanZ like family 12134
Pep3/Vps18/deep orange family 754
Predicted membrane protein (DUF2306) 1633
CST 68
Sugar-transfer associated ATP-grasp 1390
Protein of unknown function (DUF494) 4966
TniQ 2439
Acetyltransferase (GNAT) family 228200
WSC domain 3598
Uncharacterised protein family (UPF0261) 1667
Protein of unknown function (DUF1074) 81
Tudor domain 3386
Tryptophan-rich protein (DUF2389) 595
Protein of unknown function (DUF2968) 520
Domain of unknown function (DUF1885) 308
Protein of unknown function DUF72 13595
Rap1 Myb domain 339
CheD chemotactic sensory transduction 3384
Ubiquitin family 16274
Histone acetyltransferase subunit NuA4 792
Euplotes octocarinatus mating pheromone protein 8
NgoPII restriction endonuclease 139
Protein involved in formate dehydrogenase formation 5098
E1 N-terminal domain 7
Protein of unknown function (DUF2818) 746
MoaC family 20931
Vertebrate interleukin-3 regulated transcription factor 102
Citrus tristeza virus P13 protein 70
Astrovirus capsid protein precursor 2198
Prefoldin subunit 2791
Cytochrome c3 3540
ComK protein 9327
Thymidine kinase from Herpesvirus C-terminal 46
DNA mimic ocr 60
A repeated domain in UCH-protein 358
Outer mitochondrial membrane transport complex protein 644
Orbivirus outer capsid protein VP5 323
Ankyrin repeat 1686
Bacteriocin-protection 7449
Coiled-coil domain-containing protein 50 N-terminus 239
Peroxisomal membrane anchor protein (Pex14p) conserved region 1027
Bluetongue virus non-structural protein NS2 233
Lyme disease proteins of unknown function 411
Protein of unknown function (DUF3186) 2455
Domain of unknown function (DUF1874) 77
CLASP N terminal 2239
Transcription factor subunit Med10 of Mediator complex 698
Protein of unknown function (DUF3673) 51
Protein of unknown function (DUF3199) 147
Protein of unknown function (DUF3290) 1609
Coactivator-associated arginine methyltransferase 1 N terminal 137
Fibronectin-binding repeat 779
Protein of unknown function (DUF3657) 454
ADP-ribosyltransferase exoenzyme 2148
DNA gyrase C-terminal domain 37849
Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 2019
Uncharacterized protein conserved in bacteria (DUF2251) 463
Subunit 17 of Mediator complex 705
Phage T7 tail fibre protein 337
Protein of unknown function (DUF1102) 89
Diphtheria toxin 28
3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 10009
HIRAN domain 3766
Neugrin 475
Uncharacterized conserved protein (DUF2340) 280
Flagellar basal body-associated protein FliL 9782
Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 4449
Protein of unknown function (DUF3097) 2419
Hinge domain of cleavage stimulation factor subunit 2 990
Phage shock protein PspD (Phageshock_PspD) 3762
Exocyst complex component SEC3 N-terminal PIP2 binding PH 809
Armadillo-like 647
Domain of unknown function (DUF4175) 847
FlxA-like protein 1886
YodL-like 676
Protein phosphatase 2C 18211
Cysteine-rich D. radiodurans N terminus 6
Protein of unknown function (DUF2877) 6414
Hemocyanin 1103
Otx1 transcription factor 437
YvfG protein 92
Succinate dehydrogenase/Fumarate reductase transmembrane subunit 27180
Phage conserved hypothetical protein BR0599 1150
AhpC/TSA antioxidant enzyme 1442
Fels-1 Prophage Protein-like 2926
2-keto-3-deoxygluconate permease 5680
Na+/Pi-cotransporter 14677
L 58102
Transport protein Avl9 837
Aminotransferase class-III 125209
Mitochondrial carrier protein 32246
Glycosyl-hydrolase 97 N-terminal 2412
Protein of unknown function (DUF2400) 1098
Domain of unknown function DUF39 463
Bacterial protein of unknown function (YtfJ_HI0045) 6095
Protein of unknown function (DUF416) 4559
Methyl-coenzyme M reductase gamma subunit 122
L-A virus 26
Competence-damaged protein 20350
UPF0278 family 192
DDRGK domain 412
Protein of unknown function (DUF1524) 10220
TMEM117 protein family 147
Gonadotropin hormone receptor transmembrane region 208
Mini-chromosome maintenance replisome factor 375
Heterokaryon incompatibility protein (HET) 10074
Lacto-N-biose phosphorylase 599
Chaperonin 10 Kd subunit 24193
Polysaccharide biosynthesis 1023
Coronavirus 5a protein 109
DNA binding domain of tn916 integrase 2096
Phospholipase_D-nuclease N-terminal 23427
JNK_SAPK-associated protein-1 681
EURL protein 132
Domain of unknown function (DUF1882) 507
Cobalt transport protein component CbiN 2404
Glycosyl hydrolase family 66 406
Protein of unknown function (DUF1132) 294
Insect antifreeze protein repeat 69
Cupin domain 90986
Uncharacterized coiled-coil protein (DUF2353) 219
YycC-like protein 396
Cerato-platanin 544
Iron only hydrogenase large subunit 7224
MoeZ/MoeB domain 25197
Putative GTP-binding controlling metal-binding 9690
Predicted transmembrane protein 161AB 414
Rad4 transglutaminase-like domain 1321
Protein of unknown function (DUF556) 256
SNURF/RPN4 protein 40
Uncharacterized conserved protein (DUF2043) 201
Gas vesicle protein 1168
Nidogen-like 968
FeoA domain 28404
Na+/H+ antiporter subunit 13049
Domain of unknown function (DUF3898) 394
Cytochrome C biogenesis protein transmembrane region 23731
Domain of unknown function (DUF4416) 325
Nop53 (60S ribosomal biogenesis) 758
Elongation factor P (EF-P) OB domain 26371
Snake toxin 805
Domain of unknown function (DUF4180) 619
Sporozoite TA4 surface antigen 429
COMPASS (Complex proteins associated with Set1p) component N 603
CBF/Mak21 family 2229
Protein of unknown function (DUF2621) 528
EcoEI R protein C-terminal 4407
Male accessory gland secretory protein 34
CASC3/Barentsz eIF4AIII binding 651
Glycosyltransferase family 28 C-terminal domain 32149
Heat shock factor binding protein 1 671
CRISPR-associated protein Csx8 (Cas_Csx8) 61
LETM1-like protein 1670
Petal formation-expressed 219
ClpX C4-type zinc finger 20959
Mycoplasma hyorhinis VlpA repeat 12
Carcinustatin peptide 1
Protein of unknown function (DUF1651) 287
Protein of unknown function (DUF2393) 752
Coronavirus protein 7 108
Mitochondrial domain of unknown function (DUF1713) 2647
CRISPR-associated protein (Cas_Cas02710) 188
Nuclear condensing complex subunits 746
Protein of unknown function (DUF2577) 926
Protein of unknown function (DUF640) 566
Spb1 C-terminal domain 740
Citrus tristeza virus P18 protein 126
Protein of unknown function (DUF3343) 4075
NB-ARC domain 34310
WASP-binding domain of Sorting nexin protein 2880
Osteopetrosis-associated transmembrane protein 1 precursor 203
Doublecortin 1233
Degradation arginine-rich protein for mis-folding 360
Hexon 3926
Pectate lyase superfamily protein 9713
Domain of unknown function (DUF4247) 2116
Influenza A Proapoptotic protein 19172
Mediator complex subunit MED14 683
PRA1 family protein 1771
WTX protein 278
dsRNA-gated channel SID-1 389
Prepilin peptidase dependent protein C (DUF3728) 3832
Domain of unknown function (DUF4154) 5224
Domain of unknown function (DUF4338) 391
Uncharacterized ACR 13280
mRNA cap methylation 151
Protein of unknown function (DUF1236) 1053
Type II secretion system (T2SS) 6244
Cripto_Frl-1_Cryptic (CFC) 181
von Willebrand factor type A domain 34131
Casein kinase 1 gamma C terminal 433
CRISPR-associated protein Cse1 (CRISPR_cse1) 3133
Protein of unknown function (DUF3964) 281
Kidney androgen-regulated 3
YadA-like C-terminal region 9989
Cfr10I/Bse634I restriction endonuclease 25
VEGF co-regulated chemokine 1 35
Protein of unknown function (DUF1033) 6024
African swine fever virus multigene family 360 protein 142
N-terminal domain from the human glycogen debranching enzyme 551
Geminin 288
Rab geranylgeranyl transferase alpha-subunit 86
Protein N-terminal asparagine amidohydrolase 338
Delta Atracotoxin 7
Ciliary BBSome complex subunit 2 265
Cnl2/NKP2 family protein 226
Methyltransferase TYW3 743
Phenylalanine zipper 264
Protein of unknown function (DUF1474) 1846
PepSY-associated TM helix 766
Thiamine-precursor transporter protein (ThiW) 5718
Methane monooxygenase 18
Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 17214
DNL zinc finger 865
Geminivirus coat protein/nuclear export factor BR1 family 5962
Ubiquitin-2 like Rad60 SUMO-like 2257
Streptococcal 67 kDa myosin-cross-reactive antigen like family 7262
V-type ATPase 116kDa subunit family 5223
Reeler domain 966
GatB domain 16806
Protein of unknown function (DUF2012) 733
FUN14 family 966
Protein of unknown function (DUF3586) 169
Hydrogenase-1 expression protein HyaE 4067
DisA bacterial checkpoint controller nucleotide-binding 13478
Luteovirus RNA polymerase P1-P2/replicase 178
Ciliary neurotrophic factor 83
Annexin 3939
Perilipin family 894
YyzF-like protein 466
Domain of unknown function DUF59 25500
Predicted lipoprotein of unknown function (DUF2380) 78
Transcription factor Tfb2 860
Putative 2OG-Fe(II) oxygenase 650
MamI restriction endonuclease 14
Chibby family 296
PAP2 superfamily C-terminal 1166
NPCBM-associated 2716
Protein of unknown function (DUF1561) 1973
TOBE-like domain 6692
Mak16 protein C-terminal region 796
Protein of unknown function (DUF1780) 420
Root hair defective 3 GTP-binding protein (RHD3) 1047
Nitric oxide synthase 5441
Meleagrin/Cygnin family 61
Protein of unknown function (DUF1409) 268
Porcine arterivirus-type cysteine proteinase alpha 413
Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) 10
Helix-hairpin-helix motif 34577
Putative undecaprenyl diphosphate synthase 27753
Protein of unknown function (DUF1449) 4317
Wings apart-like protein regulation of heterochromatin 589
ImcF-related N-terminal domain 7040
Virus-capping methyltransferase 405
Coatomer epsilon subunit 932
GtrA-like protein 21259
Major transforming protein E5 family 33
Domain of unknown function (DUF4451) 392
Peptidyl-tRNA hydrolase 22124
Proline-rich nuclear receptor coactivator 498
2 1263
MNLL subunit 119
Transcriptional repressor TCF25 788
Protein of unknown function (DUF1528) 1587
STAT6 C-terminal 64
DNA polymerase type B 1615
Stage III sporulation protein AE (spore_III_AE) 1305
Immunity protein 37 1779
Influenza RNA-dependent RNA polymerase subunit PA 40992
Protein of unknown function (DUF1656) 10884
Protein of unknown function (DUF3260) 4082
Protein of unknown function (DUF789) 633
DUF939 C-terminal domain 6626
Quinolinate phosphoribosyl transferase 15770
FerB (NUC096) domain 766
Domain of unknown function (DUF4215) 566
Helix-turn-helix domain 7950
Mitochondrial 28S ribosomal protein S22 211
GB virus C genotype envelope 823
Protein of unknown function (DUF3491) 969
Uncharacterized conserved protein (DUF2276) 2370
RNA synthesis protein NSP10 1110
pre-mRNA processing factor 4 (PRP4) like 1336
Inorganic phosphate transporter Pho86 90
PTS system enzyme II sorbitol-specific factor 5673
Uncharacterized protein conserved in bacteria (DUF2272) 370
Cricket paralysis virus 97
Glucose-6-phosphate isomerase (GPI) 695
Disulfide bond formation protein DsbB 13096
CRISPR-associated protein (Cas_csx3) 70
ResB-like family 5993
Domain of Kin17 curved DNA-binding protein 784
Fibronectin-binding protein A N-terminus (FbpA) 10393
Transcriptional regulator Crl 4235
Uncharacterised conserved protein (DUF2315) 244
Uncharacterized protein conserved in archaea (DUF2124) 69
Domain of unknown function (DUF1788) 853
Retrotransposon gag protein 7517
Mitotic checkpoint protein 838
C-5 cytosine-specific DNA methylase 22759
TSCPD domain 3859
Brain specific membrane anchored protein 298
Vacuolar R-SNARE Nyv1 N terminal 42
Domain of unknown function (DUF366) 117
Methuselah N-terminus 208
Domain of unknown function (DUF4372) 770
Protein of unknown function (DUF3087) 355
BmTXKS1/BmP02 toxin family 30
Photosystem I reaction centre subunit III 352
Fibronectin-binding protein (FBP) 1465
Domain of unknown function (DUF4345) 873
Small 5225
Bacteriocin (Lactococcin_972) 1816
Sororin protein 84
Hepatitis delta virus delta antigen 1253
GRAS domain family 3723
NTF2 fold immunity protein 1129
Retroviral Vif (Viral infectivity) protein 11136
Voltage gated chloride channel 31592
Mitochondrial 18 KDa protein (MTP18) 527
Zinc-binding dehydrogenase 232052
HTH DNA binding domain 3444
DnaA N-terminal domain 15844
Domain of unknown function (DUF4352) 6952
Sec23/Sec24 trunk domain 3605
Repeat of unknown function (DUF1502) 5
Forkhead N-terminal region 356
Sorbitol phosphotransferase enzyme II C-terminus 5452
Hyccin 455
P21-Rho-binding domain 3887
Brinker DNA-binding domain 234
Archaeal protein of unknown function (DUF650) 406
PRELI-like family 1997
Domain of unknown function (DUF3497) 1396
Domain of Unknown Function with PDB structure (DUF3861) 1081
Protein of unknown function (DUF3710) 2606
ATP-dependent protease La (LON) domain 20720
SIR2-like domain 5934
Nucleopolyhedrovirus telokin-like protein-20 (TLP20) 79
PAS fold 52434
Tetrahydromethanopterin S-methyltransferase 81
Enolase 25633
C-terminal domain of RIG-I 459
Glycosyltransferase family 36 2289
Type IV pilus assembly protein PilX C-term 85
Scorpion toxin-like domain 568
Domain of unknwon function (DUF3824) 95
TT viral ORF2 865
Protein of unknown function (DUF2865) 350
Phosphoribosyltransferase 11780
Mandelate racemase / muconate lactonizing enzyme 29705
Pumilio-family RNA binding repeat 3397
FTO C-terminal domain 192
Protein of unknown function (DUF3270) 1083
MamL-1 domain 137
Pentatricopeptide repeat domain 10758
Calicivirus putative RNA polymerase/capsid protein 1325
Photosystem I reaction centre subunit XI 413
Protein of unknown function (DUF3682) 63
Domain of unknown function (DUF4403) 209
Scavenger receptor cysteine-rich domain 3993
Herpesvirus glycoprotein H 418
Kinetochore complex Sim4 subunit Fta1 353
Protein of unknown function (DUF1580) 20
Dedicator of cytokinesis 2354
Inorganic pyrophosphatase 15367
Conserved hypothetical phage protein (DUF2376) 414
Major fimbrial subunit protein (FimA) 1154
7TMR-DISM extracellular 2 4266
Sof1-like domain 798
Putative thioesterase (yiiD_Cterm) 4763
Putative toxin 46 247
Fibroin P25 11
Protein of unknown function (DUF3613) 757
Clostridial binary toxin B/anthrax toxin PA 588
Protein of unknown function (DUF2013) 590
Borrelia outer surface protein E 88
CRISPR-associated (Cas) DxTHG family 402
PhoPQ-activated pathogenicity-related protein 1355
HEAT repeat associated with sister chromatid cohesion 1604
Adenovirus penton base protein 384
Uncharacterised protein family (UPF0137) 260
Pyrimidine dimer DNA glycosylase 1803
Fructosamine kinase 11765
Polysaccharide biosynthesis protein 19760
Colicin C terminal ribonuclease domain 125
Mucin-2 protein WxxW repeating region 487
Chorion protein S16 39
IclR helix-turn-helix domain 62590
Winged helix DNA-binding domain 7568
DegQ (SacQ) family 88
Oxaloacetate decarboxylase 5359
CobN/Magnesium Chelatase 5804
dUTPase 31484
Archaeal protein of unknown function (DUF911) 83
Extensin-like region 197
Stage V sporulation protein family 172
C-terminal general transcription factor TFIIE alpha 249
Bacteriophage 453
Proline-rich 125
Oleosin 624
Viral late protein H2 148
Basic region leucine zipper 4120
Protein of unknown function (DUF2897) 824
Peptidase propeptide and YPEB domain 25499
Surfactant protein C 122
S-adenosylmethionine synthetase 23311
Caudovirales tail fibre assembly protein 15459
Protein of unknown function (DUF3423) 3543
Domain of unknown function (DUF4146) 448
Domain of unknown function(DUF2779) 564
RAVE protein 1 C terminal 902
Calx-beta domain 3959
Phage stabilisation protein 751
SecA preprotein cross-linking domain 29203
LlaJI restriction endonuclease 267
Ubiquitin carboxyl-terminal hydrolase 19430
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 30232
Protein of unknown function (DUF3208) 25
Extracellular mutant protein 11 251
Protein of unknown function (DUF2026) 46
GIY-YIG catalytic domain 46704
Protein of unknown function (DUF2457) 196
Protein of unknown function (DUF4043) 901
Protein of unknown function (DUF2934) 1328
Glycogen synthase kinase-3 binding 104
Protein of unknown function (DUF3431) 814
Iron-sulphur cluster biosynthesis 43686
Protein of unknown function (DUF2375) 34
SmpA / OmlA family 14915
PUB domain 1493
Retinal tissue protein 249
Nucleoside triphosphatase I C-terminal 83
NAB conserved region 1 (NCD1) 291
Fibrobacter succinogenes major domain (Fib_succ_major) 1466
Domain of unknown function (DUF3516) 883
Subtilisin inhibitor-like 327
Glucose-regulated metallo-peptidase M90 5391
Type IV pilus biogenesis 7511
FANCI solenoid 1 cap 97
Hyaluronidase protein (HylP) 431
Domain of unknown function (DUF4538) 99
TIM21 686
Protein of unknown function (DUF2380) 195
Pheophorbide a oxygenase 613
Dof domain 1994
Peptidase family S51 6971
Serum amyloid A protein 305
Domain of unknown function (DUF307) 8406
Fungal hydrophobin 355
Metallo-peptidase family M12B Reprolysin-like 985
Plasmid SOS inhibition protein (PsiB) 2887
Urease beta subunit 11964
Membrane-associated tegument protein 69
Protein of unknown function (DUF790) 382
HNH/ENDO VII superfamily nuclease with conserved GHE residues 315
Histone chaperone domain CHZ 455
Putative exonuclease 6560
GTPase-activator protein for Ras-like GTPase 3700
Poxvirus L5 protein family 79
Diacylglycerol kinase N-terminus 380
Tryptophyllin-3 skin active peptide 9
Domain of unknown function (DUF4377) 1786
Single-strand DNA-binding protein 12
Protein of unknown function (DUF809) 17
Transcription elongation factor 28311
CheB methylesterase 12710
P2 phage tail completion protein R (GpR) 4124
Domain of unknown function (DUF4300) 835
Orexin receptor type 2 91
RNA dependent RNA polymerase 1782
Calsequestrin 303
Leucine rich repeat N-terminal domain 14433
Transcriptional regulator 27069
Transferrin 1153
Muniscin C-terminal mu homology domain 810
Viral A-type inclusion protein repeat 165
Alcohol dehydrogenase transcription factor Myb/SANT-like 2259
Domain of unknown function (DUF4434) 2367
C-terminal tandem repeated domain in type 4 procollagen 1045
Anticodon nuclease activator family 28
ER protein Pkr1 366
Cortactin-binding protein-2 592
Domain of Unknown Function (DUF746) 225
MAP7 (E-MAP-115) family 585
Rubella virus endopeptidase 74
Pupal cuticle protein C1 202
Homeobox associated leucine zipper 1406
CO dehydrogenase/acetyl-CoA synthase complex beta subunit 690
Acetyl-coenzyme A transporter 1 713
Protein of unknown function (DUF1451) 4506
RNA polymerase I specific transcription initiation factor 260
Beta-catenin-interacting protein ICAT 264
Probable transposase 29439
Xyloglucan fucosyltransferase 608
Protein of unknown function (DUF422) 620
PTS system sorbose-specific iic component 25932
Alpha conotoxin precursor 429
Domain of unknown function (DUF1876) 3536
Immunoglobulin domain 24336
Repeat of unknown function (DUF1079) 113
Ferrous iron transport protein B C terminus 16973
Domain of unknown function (DUF383) 674
Protein of unknown function (DUF933) 22531
GlcNAc-PI de-N-acetylase 22458
Photosystem P840 reaction centre protein PscD 14
GTP cyclohydrolase N terminal 487
OB-fold nucleic acid binding domain 20092
Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term 832
Glycerol-3-phosphate responsive antiterminator 8002
CFEM domain 2912
L-fucose isomerase 5822
MEDS: MEthanogen/methylotroph 650
Protein of unknown function (DUF904) 4509
Domain of unknown function (DUF4454) 35
Protein of unknown function (DUF2846) 1732
TYA transposon protein 187
Glucanosyltransferase 1791
Phage terminase large subunit (GpA) 8922
Protein of unknown function (DUF2659) 55
T5orf172 domain 3927
Plasmodium RESA N-terminal 1330
XcyI restriction endonuclease 20
Immunity protein 9 20
Nrap protein 817
Type III secretion system lipoprotein chaperone (YscW) 5400
Formamidopyrimidine-DNA glycosylase N-terminal domain 27997
PGAP1-like protein 6226
Domain of unknown function (DUF4277) 754
Protein of unknown function (DUF2524) 391
Putative Flp pilus-assembly TadE/G-like 4848
Mediator complex subunit 2 172
Lsr2 4725
Y_Y_Y domain 7416
Anti sigma-E protein RseA 4908
MutS domain V 41270
A-factor biosynthesis hotdog domain 430
Eco57I restriction-modification methylase 2818
TMEM89 protein family 36
Immunity protein 26 57
MspA 1183
Dihydroprymidine dehydrogenase domain II 33567
Mitochondrial import receptor subunit TOM5 homolog 59
Ferric reductase like transmembrane component 15226
Glycoprotease family 44035
Predicted permease (DUF2074) 92
Transcription factor BRX N-terminal domain 550
Asx homology domain 679
RCSD region 27
Salmonella plasmid virulence protein SpvD 200
Biotin-requiring enzyme 113837
Protein of unknown function (DUF3963) 132
Caenorhabditis protein of unknown function 61
Prokaryotic E2 family C 36
Scorpion short toxin 162
FAD linked oxidases 38584
Bacterial regulatory proteins 142459
Uncharacterised protein family UPF0102 13397
Protein of unknown function (DUF2827) 739
Herpesvirus UL4 family 98
PHD-like zinc-binding domain 2332
Tn7 transposition regulator TnsC 232
Estrogen receptor beta 289
Glycosyl hydrolase family 1 47874
DNA ligase N terminus 5754
HaeII restriction endonuclease 43
RNAPII transcription regulator C-terminal 622
Der GTPase activator (YihI) 4508
Cytidine and deoxycytidylate deaminase zinc-binding region 4672
Domain of unknown function (DUF4624) 231
Bacteriophage abortive infection AbiH 1587
Lysosome-associated membrane glycoprotein (Lamp) 873
Matrixin 8015
MvaI/BcnI restriction endonuclease family 222
Ribbon-helix-helix domain 1391
PAS domain 856
Vacuolar sorting protein 39 domain 2 1415
Picornavirus coat protein (VP4) 11555
Adenosylmethionine decarboxylase 1282
Protein of unknown function (DUF1462) 4783
50S ribosome-binding GTPase 182073
Phage minor tail protein 7547
Putative coat protein 466
Domain of Unknown Function with PDB structure (DUF3864) 22
Protein of unknown function (DUF2587) 2095
Uncharacterised protein family (UPF0270) 4997
Protein of unknown function DUF126 1096
Putative toxin 65 2
Scaffold protein Nfu/NifU N terminal 10983
CRPV capsid protein like 319
Rotavirus non structural protein 2305
Histidine kinase 57870
HCMV glycoprotein pUL130 69
Probable lipid transfer 3019
Colipase 91
Saccharopine dehydrogenase 15191
SEA domain 2248
Multidrug resistance efflux transporter 6370
Calcitonin gene-related peptide regulator C terminal 376
Vitelline envelope receptor for lysin 118
TILa domain 497
Viral glycoprotein L 44
Protein of unknown function (DUF4007) 732
UvrB/uvrC motif 65660
Domain of unknown function (DUF4328) 2101
Small spore protein J (Spore_SspJ) 83
Rifampin ADP-ribosyl transferase 550
Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus 48
Protein phosphatase 2A regulatory B subunit (B56 family) 2249
Putative bacteriophage terminase small subunit 65
Chordopoxvirinae D3 protein 85
Cytochrome c oxidase subunit Va 707
Gamma-glutamyltranspeptidase 24885
Apc13p protein 438
Saf-pilin pilus formation protein 824
2-cysteine adaptor domain 76
NADH-Ubiquinone oxidoreductase (complex I) 48530
Eukaryotic translation initiation factor 4G1 481
Survival motor neuron protein (SMN) 879
Protein of unknown function (DUF728) 45
Domain of unknown function (DUF4394) 277
Flagellar protein YcgR 1500
STAS domain 14270
Protein of unknown function (DUF788) 738
RAD9 95
Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) 404
Domain of unknown function (DUF4145) 3069
Domain of unknown function (DUF2383) 1317
Putative Sin3 binding protein 292
cAMP phosphodiesterases class-II 655
T-cell surface glycoprotein CD3 zeta chain 179
Photosystem P840 reaction-centre cytochrome c-551 21
Autoinducer synthetase 3033
PgaD-like protein 3827
Hemolytic toxin N terminal 256
LNR domain 1137
Bacillus thuringiensis P21 molecular chaperone protein 14
Protein of unknown function (DUF663) 2289
Chorion family 3 68
Protein of unknown function (DUF2920) 963
Rho Binding 329
Triple QxxK/R motif-containing protein family 91
Mut7-C ubiquitin 2238
Protein of unknown function (DUF3274) 773
Protein of unknown function (DUF4031) 480
Protein of unknown function (DUF1313) 237
Uncharacterized protein conserved in archaea (DUF2250) 129
Prokaryotic membrane lipoprotein lipid attachment site 4733
EspF protein repeat 702
Peptide methionine sulfoxide reductase 34373
Protein of unknown function (DUF1217) 717
Prolyl oligopeptidase family 34745
Domain of unknown function (DUF336) 11394
Protein of unknown function (DUF3206) 138
Sporulation protein YtfJ (Spore_YtfJ) 2048
120 KDa Rickettsia surface antigen 154
Pseudomurein-binding repeat 106
Formiminotransferase domain 1335
Fimbrial assembly protein (PilN) 7288
Phosphatidylinositolglycan class N (PIG-N) 760
KN motif 401
RNA polymerase II elongation factor ELL 564
Protein phosphatase 2C 16442
ATP synthase (E/31 kDa) subunit 2536
Immunity protein 49 94
Protein of unknown function (DUF3628) 107
Disaggregatase related 76
Domain of Unknown Function (DUF1543) 1364
Zn-finger in Ran binding protein and others 4561
Slow voltage-gated potassium channel 372
Protein of unknown function (DUF1331) 13
Autophagy-related protein 27 558
D-aminopeptidase 332
Domain of unknown function (DUF4602) 359
Coronavirus non-structural protein NS2 88
Protein of unknown function (DUF424) 342
Protein of unknown function (DUF3906) 274
Bacterial chaperone lipoprotein (PulS_OutS) 4334
Immunity protein Imm6 157
Integral membrane protein Sed5p 91
SLBB domain 45089
Uncharacterized protein conserved in archaea (DUF2120) 38
Protein of unknown function (DUF1216) 106
Quinohemoprotein amine dehydrogenase 137
AN1-like Zinc finger 3413
SOH1 723
zinc-finger of acetyl-transferase ESCO 735
Peptidase family S48 251
Glioma tumor suppressor candidate region 424
Class-II DAHP synthetase family 5878
DHHA1 domain 61207
Adenoviral fibre protein (repeat/shaft region) 631
Beta defensin 744
NAD dependent epimerase/dehydratase family 180647
Domain of unknown function (DUF4355) 5159
WD-repeat region 295
C3 binding domain 4 of IgG-bind protein SBI 4089
Protein of unknown function (DUF2419) 715
Gene 66 (IR5) protein 87
Domain of unknown function (DUF4092) 1552
Vitamin A-deficiency (VAD) rat model signalling 39
Domain of unknown function (DUF3797) 322
Phosphoribosyl-dephospho-CoA transferase MdcG 2415
Protein of unknown function (DUF3334) 473
Domain of unknown function (DUF3819) 913
Plant invertase/pectin methylesterase inhibitor 3962
VirB8 protein 5049
PrkA AAA domain 6537
Protein of unknown function (DUF2628) 3465
tRNA synthetases class I (C) catalytic domain 25758
RNA polymerase Rpb2 26637
Glycyl-tRNA synthetase beta subunit 12346
RNA polymerase I-associated factor PAF67 894
Putative helix-turn-helix protein 8196
Herpesvirus UL56 protein 37
Got1/Sft2-like family 2337
Tenuivirus movement protein 142
Domain of unknown function (DUF3527) 273
Protein of unknown function (DUF3591) 856
Multicopper oxidase 28993
Mitochondrial protein Pet127 362
Bacteriophage lambda Kil protein 1533
Integral membrane protein (intg_mem_TP0381) 2463
Yeast cell wall synthesis protein KRE9/KNH1 254
Protein of unknown function (DUF1999) 25
PLAC (protease and lacunin) domain 1324
Protein of unknown function (DUF3985) 180
AraC-binding-like domain 9224
Ethylbenzene dehydrogenase 399
Ferritin-like domain 50323
Coiled-coil region of CCDC155 105
TfoX N-terminal domain 10686
Domain of unknown function (DUF4116) 1173
Cyanate lyase C-terminal domain 3375
Glycosyltransferase family 10 (fucosyltransferase) 3057
Holliday junction DNA helicase ruvB N-terminus 24394
Divergent 4Fe-4S mono-cluster 3730
PhoQ Sensor 3901
Protein of unknown function (DUF1389) 324
PUCC protein 1127
Bundlin 199
Xylella fastidiosa surface protein related 142
Zinc-binding domain of Paramyxoviridae V protein 211
Kelch motif 17158
Domain of unknown function (DUF4524) 115
Domain of unknown function (DUF1980) 2795
Phage holin family 6 104
Protein of unknown function (DUF3632) 756
KH domain 13918
Protein of unknown function (DUF1576) 578
XkdW protein 152
Adhesin biosynthesis transcription regulatory protein 1610
Transmembrane Fragile-X-F protein 838
COX Aromatic Rich Motif 11230
Herpesvirus UL35 family 58
S1 RNA binding domain 134638
Protein of unknown function (DUF2031) 373
Type I restriction and modification enzyme - subunit R C terminal 7633
Bsp6I restriction endonuclease 32
Protein of unknown function (DUF3179) 328
Homeodomain-like domain 3356
Protein of unknown function (DUF1328) 6562
Protein of unknown function (DUF1013) 987
Lipoprotein LpqB beta-propeller domain 2519
Kinetochore CENP-C fungal homologue 294
Domain of unknown function (DUF4574) 74
DDE superfamily endonuclease 9203
Protein of unknown function (DUF1618) 1213
DNA polymerase III polC-type N-terminus I 7432
Nonribosomal peptide synthase 7904
Islet cell autoantigen ICA69 225
ORF D-335-like protein 82
Caulimovirus viroplasmin 2720
Osteopontin 145
Doubled CXXCH motif (Paired_CXXCH_1) 1369
ABA/WDS induced protein 588
acidic terminal segments 906
C2 domain of PTEN tumour-suppressor protein 1778
Domain of unknown function (DUF697) 11265
Oligogalacturonate lyase 1074
Exo70 exocyst complex subunit 2051
Protein of unknown function (DUF3149) 622
R3H-associated N-terminal domain 436
AP2-like DNA-binding integrase domain 10901
TIR domain 9153
Agglutinin 111
Domain of unknown function (DUF1793) 914
Domain of unknown function (DUF4191) 2598
Alpha/beta hydrolase 7574
BPG-independent PGAM N-terminus (iPGM_N) 14620
Protein of unknown function (DUF3243) 710
Protein of unknown function (DUF3925) 220
Meckelin (Transmembrane protein 67) 297
Protein of unknown function (DUF1286) 64
Protein of unknown function (DUF2594) 3786
Betaherpesvirus immediate-early glycoprotein UL37 117
Domain of unknown function (DUF3535) 667
Protein of unknown function (DUF3725) 72
Putative closterovirus papain-like endopeptidase 21
Glutamate-cysteine ligase 8267
Cathepsin propeptide inhibitor domain (I29) 6131
Protein of unknown function (DUF3602) 759
Serpin (serine protease inhibitor) 9008
Mitochondrial protein from FMP27 423
Protein of unknown function (DUF1329) 3048
Nuclear pore protein 84 / 107 803
ImpA domain protein 4017
Iron/manganese superoxide dismutases 35093
DEAD/DEAH box helicase 242926
Putative papain-like cysteine peptidase (DUF1796) 626
Superinfection immunity protein 614
Predicted periplasmic lipoprotein (DUF2291) 1280
Protein of unknown function (DUF1270) 7625
Ndr family 1245
Protein of unknown function (DUF2976) 1239
Bacterial phospho-glucose isomerase C-terminal region 583
Stress-induced protein Di19 385
AKAP7 2'5' RNA ligase-like domain 1016
Glycosyltransferase family 25 (LPS biosynthesis protein) 6359
WSTF 664
Fungal calcium binding protein 20
Protein of unknown function (DUF1065) 33
Transaldolase 33914
Protein of unknown function (DUF3237) 1890
RNA ligase 1360
Corticotropin ACTH domain 2150
Domain of Unknown Function (DUF928) 448
Surface antigen variable number repeat 19590
Protein of unknown function (DUF1357) 173
Prokaryotic RING finger family 4 83
FAD dependent oxidoreductase 6902
BAR domain 4741
Rabaptin 233
Domain of unknown function (DUF4295) 538
DNA damage checkpoint protein 91
Dak1 domain 14579
Cytochrome c oxidase subunit VIa 851
Minor capsid protein from bacteriophage 362
Resolvase 69876
Protein of unknown function (DUF2726) 5589
Activator of apoptosis harakiri 16
Phage T7 capsid assembly protein 81
u-PAR/Ly-6 domain 1697
4.1 protein C-terminal domain (CTD) 720
Anticodon binding domain 79994
Phage integrase 10388
Domain of Unknown Function (DUF1086) 544
Uncharacterized conserved protein 571
Domain of Unknown Function (DUF1540) 2140
Sodium ion transport-associated 1533
Ecotin 4556
Esterase-like activity of phytase 5004
RWD domain 4199
Cytochrome C and Quinol oxidase polypeptide I 443126
Tetrahydromethanopterin S-methyltransferase MtrH subunit 161
Pre-mRNA splicing Prp18-interacting factor 832
Transmembrane family 220 336
NAD(P) transhydrogenase beta subunit 11423
Domain of unknown function (DUF2017) 2420
Type II secretion system (T2SS) 5935
Tetratricopeptide repeat 4353
Domain of unknown function 880
Phosphoprotein associated with glycosphingolipid-enriched 91
Tetratrico peptide repeat 2917
Plasmodium repeat_MYXSPDY 2
Domain of unknown function (DUF4615) 159
Severe acute respiratory syndrome coronavirus 3b protein 73
HYR domain 1100
Plectin/S10 domain 1169
Eukaryotic protein of unknown function (DUF2003) 245
PAS fold 6999
Alphavirus core protein 1137
Domain of unknown function (DUF4439) 2269
Outer membrane protein G (OmpG) 2045
Amdovirus non-structural protein 183
Leukocidin/Hemolysin toxin family 33077
Protein of unknown function (DUF2469) 2581
Domain of unknown function (DUF4488) 242
Talin 343
Vanadium/alternative nitrogenase delta subunit 145
U6-snRNA interacting domain of PrP8 855
Arginine and glutamate-rich 1 341
GXGXG motif 19004
Headcase protein family homologue 197
Phage tail tube protein FII 5685
DNA polymerase processivity factor (UL42) 143
Baculovirus polyhedron envelope protein 136
Metallopeptidase toxin 5 11
Domain of unknown function (DUF2018) 512
Pre-mRNA-splicing factor 38-associated hydrophilic C-term 270
Glycosyl hydrolase family 76 5241
Fumarylacetoacetase N-terminal 3054
Protein of unknown function (DUF1317) 1260
Antistasin family 343
Ephrin 948
Mitochondrial ribosomal protein MRP-S35 214
SseB protein N-terminal domain 6462
Glycerate kinase family 28080
EF-hand domain 142
Winged helix-turn-helix DNA-binding 6861
Protein of unknown function (DUF1355) 4606
Ftsk gamma domain 26955
Sec34-like family 684
Protein of unknown function (DUF2500) 4500
Protein of unknown function (DUF3852) 125
Hexon-associated protein (IIIa) 226
Amelogenin 499
Foie gras liver health family 1 854
Uteroglobin family 392
Bcl-2-modifying factor 96
Alpha-haemoglobin stabilising protein 45
Hint module 807
Bacteriophage Lambda NinG protein 3461
Protein of unknown function (DUF2984) 7262
DsrE/DsrF-like family 19646
Immunity protein Imm5 94
Exosome component EXOSC1/CSL4 797
BPS (Between PH and SH2) 337
Thiostrepton-resistance methylase 16
HPr Serine kinase N terminus 9235
Cytochrome oxidase assembly protein 11593
Domain of unknown function (DUF2007) 3972
ER membrane protein SH3 384
S-layer like family 177
Domain of unknown function in PX-proteins (DUF3818) 520
FCP1 113
Helicobacter outer membrane protein 11882
HdeA/HdeB family 6433
Protein of unknown function (DUF1097) 6526
Domain of unknown function (DUF897) 2484
NACHT domain 14338
MerC mercury resistance protein 1313
Endoplasmic reticulum protein ERp29 659
Kinetochore component CENP-S 533
EXS family 1947
RIH domain 1244
Taeniidae antigen 339
Snf7 6455
Galanin 144
ABC transporter 17638
Glycosyl transferase family 41 2568
Neisseria meningitidis TspB protein 636
Herpesvirus ICP4-like protein C-terminal region 219
Rogdi leucine zipper containing protein 550
Influenza C virus M2 protein 141
Protein of unknown function (DUF3638) 551
Copper resistance protein K 122
TraA 1998
Type I restriction enzyme R protein N terminus (HSDR_N) 16763
Peptidase family S49 25282
Single strand annealing-weakened 1 87
FAM183A and FAM183B related 244
Mono-functional DNA-alkylating methyl methanesulfonate N-term 2179
Domain of unknown function DUF123 442
FEZ-like protein 389
Sigma-54 12116
sic protein 450
Leucine Rich Repeat 44407
Frequency clock protein 219
Domain of unknown function (DUF4495) 120
Hepatitis core protein 10691
CcmE 6864
Transcriptional repressor 1047
NAF domain 1868
Phospholipase A2 532
Hydroxyethylthiazole kinase family 14046
Outer membrane protein (OmpH-like) 10318
C-terminal repeat of topoisomerase 3905
Protein of unknown function (DUF3676) 165
Myotubularin-like phosphatase domain 3423
Copper/zinc superoxide dismutase (SODC) 14114
SUKH-4 immunity protein 395
Immunoglobulin J chain 45
Cytomegalovirus TRL10 protein 32
Colicin-like bacteriocin tRNase domain 668
Protein of unknown function (DUF3720) 129
Protein of unknown function (DUF3939) 297
Polyketide synthesis cyclase 201
SKIP/SNW domain 891
U3-containing 90S pre-ribosomal complex subunit 596
Domain of unknown function (DUF1979) 157
FYVE zinc finger 10582
Glycosyl hydrolase family 62 433
Protein of unknown function (DUF4026) 250
Protein of unknown function (DUF1380) 4047
Tetrahydrofolate dehydrogenase/cyclohydrolase 23851
Gram-negative porin 15706
UDP-N-acetylenolpyruvoylglucosamine reductase 21508
Protein of unknown function (DUF1223) 1199
N-terminal domain of reverse transcriptase 1976
Ribosomal protein S27a 1410
Enolase 27171
Domain of unknown function (DUF3513) 501
NUC202 domain 76
Flagellar transcriptional activator (FlhC) 4427
T4-like virus tail tube protein gp19 1619
Cellulose synthase subunit D 572
Protein of unknown function (DUF2463) 67
Variant SH3 domain 15102
Cytochrome c 35098
TNF(Tumour Necrosis Factor) family 1934
Ubiquinol-cytochrome C reductase complex 163
Putative lysophospholipase 8752
NapC/NirT cytochrome c family 11813
4-hydroxyphenylacetate 3-hydroxylase C terminal 4791
Serine hydrolase 9355
Protein of unknown function (DUF1577) 832
GHKL domain 13148
Kinase/pyrophosphorylase 15164
Protein of unknown function (DUF2711) 190
Putative glucoamylase 2302
Bcl-x interacting 77
Bacterial extracellular solute-binding protein 43962
Domain of unknown function (DUF1958) 4688
Cell-wall adhesin ligand-binding C-terminal 7
CDC45-like protein 803
HIF-1 alpha C terminal transactivation domain 380
Ribosome biogenesis regulatory protein (RRS1) 788
Putative Bcl-2 like protein of testis 28
Actin interacting protein 3 529
L71 family 109
Protein of unknown function (DUF3213) 19
Protein of unknown function (DUF1251) 82
Rapamycin-insensitive companion of mTOR RasGEF_N domain 575
CG-1 domain 640
Myotoxin 28
Protein of unknown function (DUF737) 263
Rotavirus VP1 structural protein 1344
Opy2 protein 238
Bacteriophage E2-like protein 7
Amino acid permease 110288
Cytidylate kinase 20259
Orf-X protein 37
Thioredoxin-like [2Fe-2S] ferredoxin 16666
Late cornified envelope-like proline-rich protein 1 25
Meiotic cell cortex C-terminal pleckstrin homology 851
Collagenase 1922
Influenza non-structural protein (NS2) 33055
Eukaryotic glutathione synthase 1037
Thermolysin metallopeptidase 9715
Mitochondrial ATP synthase epsilon chain 701
FAR1 DNA-binding domain 2572
Domain of unknown function (DUF3560) 1886
Protein of unknown function (DUF620) 475
Autism susceptibility gene 2 protein 337
CRISPR-associated protein TM1802 (cas_TM1802) 208
Dot/Icm secretion system protein (dot_icm_IcmQ) 87
Protein of unknown function (DUF2561) 1832
Alanine-glyoxylate amino-transferase 2702
NMT1-like family 21862
Domain of unknown function (DUF4126) 1725
SapC 905
Integrin 1548
MYCBP-associated protein family 249
Phosphomevalonate kinase 292
Peptidase family M3 36771
CAP-Gly domain 4227
SNARE associated Golgi protein 80418
Olfactory receptor 4-like 347
Maltoporin periplasmic N-terminal extension 7288
WisP family N-Terminal Region 12
Helicase 5625
Bacterial capsule synthesis protein PGA_cap 8684
Domain of unknown function (DUF4566) 122
Protein of unknown function (DUF3373) 227
Ribosome 60S biogenesis N-terminal 600
POLO box duplicated region 1021
Peptide-N-glycosidase F 321
Putative peptidoglycan binding domain 34671
Bacterial fructose-1 11230
Domain of unknown function (DUF3523) 550
Domain of unknown function (DUF4218) 1029
5-carboxymethyl-2-hydroxymuconate isomerase 5177
Latexin 187
Receptor serine/threonine kinase 246
Rad52/22 family double-strand break repair protein 1440
LicD family 5882
Protein of unknown function (DUF3363) 1072
Potato leaf roll virus readthrough protein 425
Protein of unknown function 4402
Protein of unknown function (DUF4446) 674
Olfactory receptor 38300
Cytochrome b559 3451
Metaviral_G glycoprotein 871
BAFF-R 53
Plant antimicrobial peptide 60
Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) 31
Protein of unknown function 8451
Glycosyltransferase family 20 11419
Possible lysine decarboxylase 24607
H-type lectin domain 662
Spectrin repeat 4936
Secretory protein of YscJ/FliF family 15128
Kinesin motor 266
PAN-like domain 369
Domain of unknown function (DUF4201) 511
RFX1 transcription activation region 313
HutP 645
Spore germination protein GerPC 444
Domain of unknown function (DUF1985) 854
Mechanosensitive ion channel inner membrane domain 1 8645
Gkycosyl transferase family 4 group 436
Protein of unknown function (DUF1186) 233
Paired-box protein 2 C terminal 361
Outer membrane protein Omp28 259
Peptidase S24-like 88319
Polyomavirus large T antigen C-terminus 1980
Period protein 2/3C-terminal region 407
Utp11 protein 799
Transglutaminase-like superfamily 29361
Domain of unknown function (DUF3973) 238
Gluconate 2-dehydrogenase subunit 3 2599
Mago binding 561
NUDIX domain 16209
RNA binding activity-knot of a chromodomain 2446
Fe2+ transport protein 1903
Protein of unknown function (DUF3611) 355
Dolichyl-phosphate-mannose-protein mannosyltransferase 10670
Snapin/Pallidin 547
Chorismate mutase type II 31072
Amidase 54069
Transmembrane protein 18 331
Uncharacterised ACR (DUF711) 3094
Sodium:alanine symporter family 27351
Ribosomal protein S18 25007
Putative aldolase 553
MGS-like domain 50506
FtsJ-like methyltransferase 30489
Small integral membrane protein (DUF2273) 6961
CutA1 divalent ion tolerance protein 6647
pre-mRNA processing factor 3 (PRP3) 814
Kelch motif 1227
MIT (microtubule interacting and transport) domain 2461
Toxin Ldr 7333
Leucine zipper 294
Protein of unknown function (DUF3006) 829
Immunoglobulin-like domain of bacterial spore germination 153
TOBE domain 25723
Domain of unknown function (DUF3503) 106
Adenovirus late L2 mu core protein (Protein X) 168
CAP160 repeat 54
Glycine/sarcosine/betaine reductase component B subunits 2045
Protein of unknown function (DUF3457) 3343
emp24/gp25L/p24 family/GOLD 4970
USP8 interacting 191
Predicted membrane-bound metal-dependent hydrolase (DUF457) 21286
MDMPI C-terminal domain 5893
Protein of unknown function (DUF1628) 830
Repeat of unknown function (DUF1388) 128
Coatomer (COPI) alpha subunit C-terminus 954
Linear amide C-N hydrolases 10630
Alpha-L-arabinofuranosidase B 346
Abl-interactor HHR 587
Golgi 4-transmembrane spanning transporter 444
CST 177
Protein of unknown function (DUF1344) 525
Protein of unknown function (DUF667) 896
Hepatitis C virus non-structural protein E2/NS1 54491
Huntingtin protein region 165
Protein of unknown function (DUF1341) 4353
Conserved region in Nab1 111
Bacteriochlorophyll A protein 83
Class III signal peptide 328
Dispersed gene family protein 1 of Trypanosoma cruzi region 5 616
Chlamydia polymorphic membrane protein middle domain 1965
Domain of unknown function (DUF3552) 9747
Filovirus membrane-associated protein VP24 47
Protein of unknown function (DUF999) 19
Mitochondrial-associated sphingomyelin phosphodiesterase 298
Protein of unknown function (DUF3035) 347
Ferritin-like 491
Oligonucleotide/oligosaccharide-binding (OB)-fold 15898
Domain of unknown function (DUF1735) 2001
Fcf2 pre-rRNA processing 742
Protein of unknown function (DUF4106) 366
Baculovirus P24 capsid protein 94
Amidohydrolase 15738
Chloramphenicol phosphotransferase-like protein 2125
Protein of unknown function (DUF3486) 1086
UBA-like domain 3946
Joubert syndrome-associated 96
N-terminal C2 in EEIG1 and EHBP1 proteins 1741
Predicted integral membrane metal-binding protein (DUF2296) 755
Putative treble-clef 125
KicB killing factor 4500
Phage shock protein B 4421
Arabidopsis broad-spectrum mildew resistance protein RPW8 329
Protein phosphatase inhibitor 765
Erythronolide synthase 15
Domain of unknown function (DUF4460) 336
Alg9-like mannosyltransferase family 2887
Calcineurin-binding protein (Calsarcin) 389
Alkali metal cation/H+ antiporter Nha1 C terminus 310
Gene 25-like lysozyme 16841
EVE domain 8205
T-antigen specific domain 374
Protein of unknown function (DUF554) 6544
BAG domain 1580
Phage portal protein 8520
NinB protein 2721
Gyrovirus capsid protein (VP1) 681
Utp8 family 89
YqjK-like protein 3897
Rubisco LSMT substrate-binding 1379
Carbohydrate binding module (family 6) 3419
Domain of unknown function (DUF956) 2389
Kinesin-associated microtubule-binding 345
DAN domain 679
tRNA-splicing endonuclease subunit sen54 N-term 641
Rab3 GTPase-activating protein catalytic subunit 425
Nucleolar GTP-binding protein 1 (NOG1) 1120
Antirestriction protein Ral 587
Lipase maturation factor 2477
Protein of unknown function (DUF4063) 848
VacJ like lipoprotein 8481
Globin 20019
IBV 3A protein 107
Ceroid-lipofuscinosis neuronal protein 5 119
WHG domain 11303
Ribosomal protein L22p/L17e 24811
SART-1 family 870
Corticotropin-releasing factor family 267
Glu-tRNAGln amidotransferase C subunit 15829
Cucumovirus protein 2B 210
Invariant surface glycoprotein 215
Protein of unknown function (DUF587) 65
Type II secretory pathway pseudopilin 977
Differentiation and proliferation regulator 183
VTC domain 2594
ATP synthase protein 8 9709
Protein of unknown function (DUF740) 346
DDE superfamily endonuclease 5619
Pombe specific 5TM protein 5
Periplasmic binding protein 35605
La domain 3118
ssDNA binding protein 102
Probable DNA packing protein 338
Stress-inducible humoral factor Turandot 51
BRCA2 416
XFP N-terminal domain 3718
Protein of unknown function (DUF2931) 1366
Intein splicing domain 2270
PIN domain 4612
Protein of unknown function (DUF1203) 472
23S rRNA methylase leader peptide (ErmC) 101
Protein of unknown function (DUF4017) 211
Frog antimicrobial peptide 532
SUR7/PalI family 2026
Protein of unknown function (Duf2374) 302
Bacterial protein of unknown function (DUF977) 4404
TMEM210 family 23
Protein of unknwon function (DUF3310) 6026
ThiC family 12573
Domain of unknown function (DUF3490) 361
Origin recognition complex (ORC) subunit 4 C-terminus 667
Adenylate cyclase associated (CAP) N terminal 964
YHS domain 4380
Potyvirus P1 protease 2040
Bacterial protein of unknown function (DUF896) 12556
Domain of unknown function (DUF4595) with porin-like fold 313
Dihydrodipicolinate reductase 20863
FAM163 family 185
Regulator of RNA polymerase sigma(70) subunit 4780
Domain of unknown function (DUF1989) 4652
Domain of unknown function (DUF4341) 3213
YfdX protein 3884
Symplekin tight junction protein C terminal 486
Secreted repeat of unknown function 1711
DNA-K related protein 694
RNA pseudouridylate synthase 121213
Protein of unknown function (DUF1230) 326
Carbon monoxide dehydrogenase subunit G (CoxG) 3832
Ubiquitin-specific peptidase-like 122
Encapsulating protein for peroxidase 2416
Ribosomal L27 protein 21767
Protein of unknown function (DUF2599) 2195
Bacteriophage T4 133
TFIIE beta subunit core domain 516
N-(5'phosphoribosyl)anthranilate (PRA) isomerase 16957
T4 gene Gp59 loader of gp41 DNA helicase 141
Domain of unknown function (DUF4055) 2189
Spike receptor binding domain 970
Bacterial regulatory proteins 196901
DnaB-helicase binding domain of primase 14062
Iron-binding zinc finger CDGSH type 2476
Response regulator receiver domain 618516
Protein of unknown function (DUF2947) 425
Cytochrome c bacterial 195
Sulfite exporter TauE/SafE 57253
F-box domain 22546
MIR domain 3170
Basal layer antifungal peptide (BAP) 22
Protein of unknown function (DUF1637) 728
SH3 domain 18119
Domain of unknown function (DUF1970) 7
Accessory gene regulator B 6281
Protein of unknown function (DUF3910) 220
Domain of unknown function (DUF1965) 199
Tetratricopeptide repeat 13712
WW domain binding protein 11 621
Methyltransferase domain 6246
Bacterial protein of unknown function (DUF876) 8746
APOBEC-like C-terminal domain 89
Protein of unknown function (DUF615) 6980
C-terminal domain of homeodomain 1 50
DNA N-6-adenine-methyltransferase (Dam) 3551
PAS fold 41746
Phage regulatory protein Rha (Phage_pRha) 7649
(2R)-phospho-3-sulfolactate synthase (ComA) 661
FaeA-like protein 2014
Cytotoxic 465
Sulfocyanin (SoxE) 119
WD40 associated region in TFIID subunit 944
Phage holin protein (Holin_LLH) 678
COPI associated protein 781
Tap 353
Prokaryotic glutathione synthetase 8301
Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) 104
lactate/malate dehydrogenase 37889
Domain of unknown function (DUF4559) 88
DASH complex subunit Hsk3 like 387
Aralkyl acyl-CoA:amino acid N-acyltransferase 286
Acyl CoA binding protein 3763
Transmembrane protein 138 181
Protein of unknown function (DUF2512) 1011
PRANC domain 667
Leucine-tRNA synthetase-specific domain 15
Fibrinogen alpha C domain 87
PAS fold 2910
Protein of unknown function (DUF1021) 7486
Nse4 C-terminal 843
Protein of unknown function (DUF1020) 1067
WSTF 761
Sialidase enzyme penultimate C terminal domain 31
Keratinocyte differentiation-associated 42
Sea anemone cytotoxic protein 95
Domain of unknown function (DUF1964) 122
Zinc finger 7795
Domain of unknown function (DUF4010) 2135
Duffy binding protein N terminal 96
Pyridoxal-phosphate dependent enzyme 156060
CsiD 3603
Glycosyl hydrolases family 32 C terminal 13812
Allantoicase repeat 2607
Protein of unknown function (DUF2772) 411
Histidine kinase N terminal 344
Raptor N-terminal CASPase like domain 818
Phage protein Gp19/Gp15/Gp42 508
GPI-anchored cell wall organization protein 120
CLN3 protein 808
Rift valley fever virus non structural protein (NSs) like 309
AAA-like domain 24648
Putative toxin 53 83
Choline kinase N terminus 333
3-demethylubiquinone-9 3-methyltransferase 19827
Thiamine pyrophosphate enzyme 121868
Protein of unknown function (DUF3020) 84
Moulting cycle 215
Protein of unknown function (DUF2894) 505
Serpentine type 7TM GPCR receptor class ab chemoreceptor 365
PTRF/SDPR family 380
Rep protein catalytic domain like 369
SnoaL-like domain 33539
Hepatitis C virus non-structural protein NS4b 2697
UreD urease accessory protein 11650
NQR2 9927
CW-type Zinc Finger 1562
IgA Peptidase M64 782
Rhabdovirus spike glycoprotein 4895
Rab interacting lysosomal protein 374
Protein of unknown function (DUF3300) 4066
Sensory domain of two-component sensor kinase 14417
HNH/Endo VII superfamily nuclease toxins 223
Protein of unknown function (DUF4046) 256
Alcohol dehydrogenase GroES-like domain 231291
Alkaline phosphatase 13502
Bartter syndrome 58
Protein of unknown function (DUF837) 407
SigmaK-factor processing regulatory protein BofA 1016
Listeria-Bacteroides repeat domain (List_Bact_rpt) 4152
Gap junction channel protein cysteine-rich domain 2352
Protein of unknown function (DUF1525) 1114
PrgI family protein 1733
Phosphoprotein P region PCT disordered 49
Asparagine synthase 21433
Methionine biosynthesis protein MetW 2876
Domain of unknown function DUF83 2907
NeuB family 4873
Methyltransferase domain 14083
DEAD/H associated 6609
SRP54-type protein 48692
Pseudin antimicrobial peptide 4
Domain of unknown function (DUF4388) 783
Domain of unknown function (DUF362) 2664
Domain of unknown function (DUF2382) 1146
Protein of unknown function (DUF2794) 738
Kinetochore Sim4 complex subunit FTA2 222
Protein of unknown function (DUF3549) 537
Cell differentiation family 1044
C-terminal region of aryl-sulfatase 1830
Sas10 C-terminal domain 752
Domain of unknown function (DUF1982) 1605
Protein of unknown function (DUF3353) 496
SSXT protein (N-terminal region) 665
NPL4 family 871
Exocyst complex component Sec10 1238
Bacterial conjugation TrbI-like protein 7841
DNA polymerase processivity factor 1026
Sarcoglycan alpha/epsilon 342
Divergent CCT motif 878
Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 95
Protein of unknown function (DUF3166) 350
Deltaretrovirus Tax protein 35
Oligogalacturonate-specific porin protein (KdgM) 7933
Cold acclimation protein WCOR413 266
Mediator of RNA polymerase II transcription complex subunit 8 558
Nine Cysteines Domain of family 3 GPCR 3483
Aida N-terminus 147
Protein of unknown function (DUF2654) 78
Domain of unknown function (DUF377) 2480
LlaMI restriction endonuclease 13
Ethanolamine ammonia-lyase light chain (EutC) 6878
Domain of unknown function (DUF4491) 469
YMGG-like Gly-zipper 1813
Phostensin PP1-binding and SH3-binding region 172
Domain of unknown function (DUF4609) 35
Plug domain of Sec61p 1526
Replication initiator protein A 1186
TACI 79
Viral DNA-binding protein 237
Transcriptional activator TraM 159
Protein of unknown function (DUF3920) 227
Protein of unknown function (DUF1162) 1614
Protein of unknown function 199
High-temperature-induced dauer-formation protein 695
HTH domain 66747
Ribosomal protein L9 21381
VASP tetramerisation domain 416
Domain of unknown function (DUF3890) 153
UAF complex subunit Rrn10 124
Yeast PIR protein repeat 438
SH2 domain 764
Putative RNA methylase family UPF0020 17943
FHIPEP family 17011
Syd protein (SUKH-2) 4504
Protein of unknown function (DUF3539) 174
Immunity protein 21 167
UDP-glucose/GDP-mannose dehydrogenase family 32081
rRNA processing 405
SecD/SecF GG Motif 29616
Protein of unknown function (DUF342) 2670
Hypothetical protein Yopt 22
Necrosis inducing protein-1 31
Protein of unknown function (DUF727) 387
Cofactor of BRCA1 (COBRA1) 259
Protein of unknown function (DUF2573) 345
Phosphoribosyl synthetase-associated domain 25569
Domain of unknown function (DUF4640) 65
Topoisomerase VI B subunit 458
VRR-NUC domain 8430
CD4 133
AT-hook-containing transcription factor 106
RNA binding protein She2p 47
Protein of unknown function (DUF3018) 1840
Protein of unknown function (DUF1345) 2546
Coiled-coil domain containing 32 189
Protein of unknown function (DUF655) 352
M42 glutamyl aminopeptidase 27067
AccI restriction endonuclease 29
GGDEF domain 174771
Metallopeptidase toxin 3 18
FGGY family of carbohydrate kinases 74511
Macrophage colony stimulating factor-1 (CSF-1) 79
Ribosomally synthesized peptide in Bacteroidetes 24
Protein of unknown function (DUF2001) 1145
Uncharacterized conserved protein (DUF2365) 240
Autophagy protein Apg17 480
Filaggrin 38
Protein of unknown function (DUF3987) 4391
Protein of unknown function DUF45 13004
L-arabinose isomerase 5451
Cotton fibre expressed protein 1649
Baculovirus E66 occlusion-derived virus envelope protein 125
SnoaL-like domain 12092
Protein of unknown function (DUF726) 1398
Nicotianamine synthase protein 738
T4 recombination endonuclease VII 76
RasGAP C-terminus 1078
Protein of unknown function (DUF1201) 8
Protein of unknown function (DUF1635) 254
Domain of unknown function (DUF4475) 280
Prokaryotic N-terminal methylation motif 23574
Fungal protein of unknown function (DUF1748) 412
Transcriptional regulatory protein 269333
Protein of unknown function (DUF524) 663
Pkip-1 protein 62
Phytoreovirus outer capsid protein P8 19
Protein of unknown function (DUF619) 1110
Ubiquitin-associated 35
Domain of unknown function (DUF4397) 1266
Stress up-regulated Nod 19 224
Domain of unknown function (DUF4587) 147
Cell division protein 48 (CDC48) 4540
Salmonella-Shigella invasin protein C (IpaC_SipC) 1147
Replication regulatory protein RepB 2844
SacI restriction endonuclease 32
Surface lipoprotein of Spirochaetales order 351
Phage shock protein G (Phageshock_PspG) 4097
Protein of unknown function (DUF1678) 16
Domain of unknown function (DUF1903) 492
Protein of unknown function (DUF3216) 20
Protein of unknown function (DUF1228) 6099
7TM-HD extracellular 2616
Domain of unknown function (DUF1993) 1956
Zona pellucida-like domain 4819
B-block binding subunit of TFIIIC 723
Protein of unknown function (DUF1149) 1979
Conserved region of Rad21 / Rec8 like protein 1134
Glycosyl hydrolase family 80 of chitosanase A 15
YodA lipocalin-like domain 9969
Uncharacterised conserved protein (DUF2373) 528
Chromatin assembly factor 1 complex p150 subunit 663
Neuraminidase 54437
Protein of unknown function (DUF2919) 4229
RFX5 DNA-binding domain 54
PglZ domain 1544
Major royal jelly protein 1723
JmjC domain 5855
Ehrlichia tandem repeat (Ehrlichia_rpt) 28
Domain of unknown function (DUF281) 35
DNA methylase 26482
Armadillo/beta-catenin-like repeat 9036
Cartilage oligomeric matrix protein 368
Vps23 core domain 811
Pyruvate kinase 29088
Clp amino terminal domain 47967
Protein of unknown function (DUF2740) 317
Domain of unknown function (DUF4462) 32
Phlebovirus glycoprotein G2 569
T4-like phage nuclear disruption protein (Ndd) 61
Cysteine-rich secretory protein family 24851
tRNA synthetases class I (M) 38014
Protein of unknown function (DUF3713) 83
Ornithine cyclodeaminase/mu-crystallin family 12675
Ribonuclease R winged-helix domain 5629
Replication protein A interacting N-terminal 218
RS4NT (NUC023) domain 1548
Acyl-CoA dehydrogenase 159864
GNS1/SUR4 family 4010
Guanine nucleotide exchange factor in Golgi transport N-terminal 2550
Protein of unknown function (DUF3763) 4197
Protein of unknown function (DUF1581) 42
PsbP 1187
Cob(I)alamin adenosyltransferase N terminal 6014
Restriction endonuclease ThaI 50
Type II restriction endonuclease (RE_Alw26IDE) 146
RII binding domain 205
Conserved hypothetical protein 2217 (DUF2460) 911
PetN 2248
Squalene/phytoene synthase 13712
Transcription initiation factor IIA 798
NurA domain 934
Protein of unknown function (DUF436) 6852
Calcium-activated potassium channel 431
Low iron-inducible periplasmic protein 27
Putative nucleotidyltransferase substrate binding domain 2869
Ceramidase 1356
Chitin synthase 2126
Multiubiquitin 293
Integron-associated effector binding protein 2657
Killing trait 1448
Pectic acid lyase 439
Gaa1-like 735
Prokaryotic homologs of the JAB domain 9996
VPR/VPX protein 8393
Oestrogen-type nuclear receptor final C-terminal 162
Domain of unknown function (DUF4581) 98
Bacterial cellulose synthase subunit 6040
XdhC Rossmann domain 13223
FANCL C-terminal domain 509
Eukaryotic protein of unknown function (DUF846) 986
Orthopoxvirus A47 protein 60
IncA protein 938
3-hydroxyacyl-CoA dehydrogenase 43212
Domain of unknown function (DUF4647) 60
Cancer susceptibility candidate 1 174
Colicin V production protein 19169
Yeast mitochondrial distribution and morphology (MDM) proteins 458
D-ala D-ala ligase C-terminus 28805
Microfibril-associated glycoprotein (MAGP) 190
Formin Homology 2 Domain 4737
TAZ zinc finger 1134
Multi-glycosylated core protein 24 (MGC-24) 273
Protein trafficking PGA2 254
Nucleopolyhedrovirus p26 protein 158
ATP synthase subunit H 710
Repeat of unknown function (DUF346) 44
Pentapeptide repeats (8 copies) 32577
CRT10 261
Late embryogenesis abundant protein 486
TEP1 N-terminal domain 43
Autophagocytosis associated protein C-terminal 760
ATP-grasp domain 19876
Opacity family porin protein 1441
Poly A polymerase regulatory subunit 171
Type III secretion system protein PrgH-EprH (PrgH) 2583
FANCI solenoid 1 251
Transposase DDE domain 6610
Acyl-CoA dehydrogenase C terminal 412
Ribose-5-phosphate isomerase 2820
Secretin and TonB N terminus short domain 20477
Beta-1 413
TMC domain 1007
DNA primase catalytic core 22141
RNA polymerase III subunit Rpc25 782
Domain of unknown function (DUF1962) 12
Caudal like protein activation region 280
Domain of unknown function (DUF4623) 29
Domain of unknown function (DUF1891) 144
Protein of unknown function (DUF1215) 8122
Arabinofuranosyltransferase A C terminal 2010
Protein of unknown function (DUF1501) 2741
Churchill protein 118
Ribosomal protein L4/L1 family 23436
L1 transposable element 1952
SecA Wing and Scaffold domain 28699
AsmA-like C-terminal region 10602
Adhesin lipoprotein 28
RanBP1 domain 2644
Histone deacetylase domain 18397
Fibronectin-attachment protein (FAP) 1836
Domain of unknown function (DUF4149) 2411
RNA polymerase Rpb6 21192
VMA21-like domain 657
Type 4 fimbrial biogenesis protein PilY2 218
Inheritance of peroxisomes protein 1 270
SRP72 RNA-binding domain 684
Domain of unknown function (DUF4572) 74
Zinc-finger of mitochondrial splicing suppressor 51 356
Peptidase family S49 N-terminal 6277
Salmonella virulence plasmid 28.1kDa A protein 680
Orn/Lys/Arg decarboxylase 29780
Plasmid protein of unknown function (Plasmid_RAQPRD) 1256
Immunity protein 43 90
V antigen (LcrV) protein 454
Cytokinin dehydrogenase 1 682
Plant mobile domain 2971
Herpesvirus ICP4-like protein N-terminal region 192
Mouse development and cellular proliferation protein Cullin-7 344
PcfK-like protein 1120
Archaeal putative transposase ISC1217 258
Interleukin-6 receptor alpha chain 1006
YwhD family 4766
PAXIP1-associated-protein-1 C term PTIP binding protein 141
Acyl-coenzyme A oxidase N-terminal 1405
Extensin-like protein repeat 39
Bacterial surface layer protein 912
Pirin C-terminal cupin domain 11315
Isochorismatase family 72309
FRG1-like family 585
BetR domain 757
MerT mercuric transport protein 1490
Bestrophin 8992
N-glycosylation protein 286
Head fiber protein 182
Cytochrome oxidase subunit II 25764
No apical meristem-associated C-terminal domain 775
NUC205 domain 70
TrbL/VirB6 plasmid conjugal transfer protein 6154
ORMDL family 961
Fibrillar collagen C-terminal domain 1840
Bacterial Ig-like domain (group 3) 9543
Glycosyl transferase family 2 177722
PhTx neurotoxin family 6
Aspartate/ornithine carbamoyltransferase 53588
RNA polymerase II transcription mediator complex subunit 9 439
IpaB/EvcA family 1757
BMC domain 31948
Uncharacterized conserved protein (DUF2280) 1872
Elongation factor SelB 5880
YycH protein 5921
PIN domain 7486
Apolipoprotein A-II (ApoA-II) 66
Sperm acrosome-associated protein 7 19
Putative oxalocrotonate tautomerase enzyme 439
Domain of unknown function (DUF4177) 3098
Ornatin 7
Protein of unknown function (DUF551) 5506
Spumavirus aspartic protease (A9) 37
Triosephosphate isomerase 27454
Domain of unknown function (DUF1860) 7
Eukaryotic membrane protein family 792
Bacterial transcriptional repressor 17404
S-100/ICaBP type calcium binding domain 1747
Porphobilinogen deaminase 18306
Protein of unknown function (DUF1072) 47
Siderophore-interacting FAD-binding domain 11760
Firmicute plasmid replication protein (RepL) 1903
Domain of unknown function (DUF1975) 25770
Archaeal PaREP1/PaREP8 family 559
Protein of unknown function (DUF4529) 60
Protein of unknown function (DUF2773) 2666
Surfactant-associated protein 2 25
Rft protein 795
VirE N-terminal domain 1232
Sigma-54 interaction domain 106332
Immunity protein 8 60
Protein of unknown function (DUF1653) 2877
Domain of Unknown Function (DUF1081) 273
Primosomal replication protein priB and priC 4727
Protein of unknown function (DUF2717) 51
Maintenance of mitochondrial structure and function 2843
Mitochondrial 28S ribosomal protein S30 (PDCD9) 412
Toxin co-regulated pilus biosynthesis protein Q 1832
Protein of unknown function (DUF1284) 705
Protein of unknown function (DUF1652) 682
PH domain associated with Beige/BEACH 1952
N-acetylglucosaminyl transferase component (Gpi1) 798
Ethanolamine utilisation protein EutA 4444
Protein of unknown function (DUF1475) 116
Kinase binding protein CGI-121 965
N-terminal region of micro-spherule protein 323
Family 104 129
Xyloglucan endo-transglycosylase (XET) C-terminus 2078
Manganese containing catalase 5648
Spore cortex protein YabQ (Spore_YabQ) 1234
Protein of unknown function (DUF975) 4456
Possible tRNA binding domain 4546
Regulatory CLIP domain of proteinases 814
Nsp1-like C-terminal region 838
POU domain 140
Domain of unknown function (DUF1972) 1735
Eukaryotic aspartyl protease 10514
Lipase 3283
Winged helix-turn-helix DNA-binding 57907
Protein of unknown function 1971
OST-HTH Associated domain 253
Protein of unknown function (DUF3929) 222
Family of unknown function (DUF648) 221
Serine-rich domain associated with BRCT 1689
Phage integrase SAM-like domain 3244
DX module 39
Rough deal protein C-terminal region 228
Regulator of chromosome condensation (RCC1) repeat 4793
Protein of unknown function (DUF1342) 5006
Formyl transferase 27104
Methyltransferase involved in Williams-Beuren syndrome 772
Nicastrin 472
Adaptor complexes medium subunit family 4877
Dihydroxyacetone kinase family 10617
Protein of unknown function (DUF2744) 181
Protein of unknown function (DUF1643) 6685
Orthopoxvirus A26L/A30L protein 133
Catalytic beta propeller domain of bacteriophage endosialidase 163
Divergent PAP2 family 2045
Phosphoenolpyruvate carboxylase 12278
Aralkyl acyl-CoA:amino acid N-acyltransferase 247
Protein of unknown function (DUF2838) 550
Serpentine type 7TM GPCR chemoreceptor Srt 507
Xanthomonas XOO_2897-like deaminase 153
Alanine racemase 69855
Uncharacterized BCR 27341
Protein of unknown function (DUF1031) 58
Testis-expressed 12 52
Prokaryotic acetaldehyde dehydrogenase 5244
Domain of unknown function (DUF3328) 2188
Interferon-alpha/beta receptor 1216
YopJ Serine/Threonine acetyltransferase 1289
Protein of unknown function (DUF4001) 796
Rio2 1050
Domain of unknown function (DUF3814) 11071
WisP family C-Terminal Region 5
Hexon 1321
Protein of unknown function (DUF1761) 870
Microtubule associated protein (MAP65/ASE1 family) 1337
Domain of unknown function (DUF4124) 5649
Protein of unknown function (DUF2715) 156
Ca2+ regulator and membrane fusion protein Fig1 392
Ca2+ insensitive EF hand 1175
Protein of unknown function (DUF1563) 312
Glycosyl-hydrolase 97 C-terminal 2412
Domain of unknown function (DUF4034) 1589
Borrelia lipoprotein 641
Regulator of G protein signalling-like domain 424
GrpB protein 11260
Cenp-O kinetochore centromere component 477
D-galactarate dehydratase / Altronate hydrolase 12551
FAM196 family 201
Transcriptional Coactivator p15 (PC4) 3478
Domain of unknown function (DUF1974) 6927
FlgN protein 7922
Hepcidin 243
G-rich domain on putative tyrosine kinase 15473
Ubiquitin-like domain 1286
Xylanase inhibitor N-terminal 4162
mttA/Hcf106 family 28909
CO dehydrogenase/acetyl-CoA synthase delta subunit 1052
PKA-RI-RII subunit binding domain of A-kinase anchor protein 129
Immunity protein 48 58
Methylamine utilisation protein MauE 1000
Apoptosis-antagonizing transcription factor 729
Caenorhabditis elegans Her-1 21
Domain of unknown function (DUF4380) 274
FAM75 family 328
Bpu10I restriction endonuclease 64
Winged helix DNA-binding domain 1369
Caveolin 543
Protein of unknown function (DUF3723) 485
Alpha mannosidase 9386
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 51585
Mediator complex subunit 27 391
Protein of unknown function (DUF1381) 9316
Domain of Unknown Function (DUF902) 342
Disintegrin 3911
Exonuclease C-terminal 5550
Protein of unknown function (DUF2841) 438
Domain of unknown function (DUF4071) 783
N-terminal glycosyl-hydrolase-114-associated domain 14
DnaJ central domain 27971
Protein of unknown function (DUF3984) 195
RsbT co-antagonist protein rsbRD N-terminal domain 506
Sterol methyltransferase C-terminal 805
Tetracyclin repressor 7494
DNA polymerase III beta subunit 21840
SMI1-KNR4 cell-wall 614
Papillomavirus helicase 1564
Zinc finger 11293
FERM C-terminal PH-like domain 4392
Glucodextranase 9
Transposase IS116/IS110/IS902 family 30202
Bacterial OB fold (BOF) protein 10726
Diaphanous FH3 Domain 1999
Ribosomal protein S12/S23 25259
Bacterial putative lipoprotein (DUF940) 6501
CST 123
Protein of unknown function (DUF3951) 373
Bacterial dnaA protein 29069
Protein of unknown function (DUF3962) 217
U1 small nuclear ribonucleoprotein of 70kDa MW N terminal 743
ROS/MUCR transcriptional regulator protein 2075
Dot/Icm substrate protein 161
Divalent cation transporter 16348
Protein of unknown function (DUF3430) 130
Lipocalin / cytosolic fatty-acid binding protein family 413
Zinc-binding domain of primase-helicase 3925
Domain of unknown function (DUF1966) 470
Involucrin of squamous epithelia N-terminus 48
Planctomycete extracellular 85
Gp5 N-terminal OB domain 129
Ribosomal L40e family 1165
Transcriptional regulator 556
2OG-Fe(II) oxygenase superfamily 19307
Immunoglobulin I-set domain 31267
Syntaxin 3596
Ricin-type beta-trefoil lectin domain 10126
YejG-like protein 3805
Magnesium transporter NIPA 3476
VID27 cytoplasmic protein 597
Methane/Phenol/Toluene Hydroxylase 2549
Adaptin N terminal region 8226
Phosphate transporter family 25072
Ubiquinol-cytochrome c reductase 8 kDa 136
Elongation factor P 26319
Protein of unknown function (DUF4233) 2357
Papain-like auto-proteinase 79
YhfH-like protein 382
Mitochondrial Myo2 receptor-related protein 41
TFIIB zinc-binding 3093
Uncharacterised protein family UPF0546 558
Mitochondrial import receptor subunit TOM6 homolog 55
Fanconi anemia group F protein (FANCF) 145
Growth hormone receptor binding 1899
Putative zinc ribbon domain 1615
Maf1 regulator 830
STAT protein 1048
GA-binding protein alpha chain 179
FAM101 family 211
2-enoyl-CoA Hydratase C-terminal region 7360
BRCA2 432
Domain of unknown function (DUF1957) 2432
Domain of unknown function (DUF4528) 113
Myb/SANT-like DNA-binding domain 1059
G protein-coupled glucose receptor regulating Gpa2 770
Kinase-like 453
Intra-flagellar transport protein 57 350
Predicted SPOUT methyltransferase 17674
Uncharacterised protein family UPF0561 95
Protein of unknown function (DUF3189) 411
N2 1539
WPP domain 351
Protein of unknown function (DUF3745) 2587
Photosystem II reaction centre T protein 2933
tRNAHis guanylyltransferase 948
Polymyxin resistance protein PmrD 3387
Coiled-coil protein 142 110
Nucleoside-specific channel-forming protein 10186
Rice dwarf virus p3 12
SicP binding 985
Domain of unknown function (DUF1959) 40
Uncharacterised protein family (UPF0146) 188
Protein of unknown function (DUF1106) 59
PV-1 protein (PLVAP) 100
Protein of unknown function (DUF2763) 293
HD containing hydrolase-like enzyme 5013
Ubinuclein conserved middle domain 315
Caspase activity and apoptosis inhibitor 1 159
PPR repeat family 26133
A nuclease of the HNH/ENDO VII superfamily with conserved LHH 388
Gram-negative porin 27642
Protein of unknown function (DUF4254) 757
PEP-utilising enzyme 43328
Salmonella outer protein D 1911
Serpentine type 7TM GPCR chemoreceptor Sru 270
Domain of unknown function (DUF1880) 73
Pseudouridine synthase II TruB 7523
Protein of unknown function (DUF1676) 732
Ciliary BBSome complex subunit 2 246
Viral family 110 97
Domain of unknown function (DUF4195) 213
Protein of unknown function (DUF4244) 2544
Bacterial shufflon protein 2161
GPI-GlcNAc transferase complex 621
Protein of unknown function (DUF1439) 4578
Zinc knuckle 417
Schwannomin-interacting protein 1 246
Osteoregulin 82
Protein of unknown function (DUF3466) 533
Protein of unknown function (DUF2690) 530
Domain of unknown function (DUF3362) 6542
Putative nucleotidyltransferase DUF294 3095
Protein of unknown function 285
Protein of unknown function (DUF2960) 437
Bacterial purine repressor 7413
D-lactate dehydrogenase 5841
Poxvirus F11 protein 82
Ribonuclease-III-like 21514
Protein of unknown function (DUF1604) 577
Telomere-length maintenance and DNA damage repair 433
Blue/Ultraviolet sensing protein C terminal 177
Protein of unknown function (DUF2802) 1063
Zinc-finger (CX5CX6HX5H) motif 343
Phage Tail Protein X 6815
AAA domain 8907
UreF 11726
Bacterial protein of unknown function (DUF853) 8360
SLIDE 1056
Domain of unknown function (DUF3440) 6068
DNA polymerase III 4607
SdpI/YhfL protein family 3336
PHB accumulation regulatory domain 1184
YARHG domain 1744
Alba 1684
DctM-like transporters 26530
Apolipoprotein C-I (ApoC-1) 73
Arylsulfotransferase (ASST) 6214
MAPEG family 11125
Male gamete fusion factor 224
Primase zinc finger 673
Domain of unknown function (DUF4466) 30
Protein of unknown function (DUF3574) 1102
Protein of unknown function (DUF1777) 705
PLU-1-like protein 1053
Protein of unknown function (DUF1336) 1070
Domain of unknown function (DUF4158) 6275
Pericardin like repeat 16
Protein of unknown function (DUF3767) 516
Ribosomal protein L23 1182
BEN domain 1284
Protein of unknown function (DUF1002) 2333
Protein of unknown function (DUF1318) 4431
Nucleoporin autopeptidase 1122
CHASE domain 3314
Protein of unknown function (DUF2631) 1993
Nup53/35/40-type RNA recognition motif 145
PaaX-like protein C-terminal domain 6420
Uncharacterised protein family UPF0542 116
Reoviridae VP9 14
Respiratory-chain NADH dehydrogenase 22960
Protein of unknown function (DUF1700) 7933
Domain of unknown function (DUF1744) 744
DNA-directed RNA polymerase N-terminal 1196
WWE domain 1577
Shikimate / quinate 5-dehydrogenase 41849
Domain of unknown function (DUF3473) 580
RNA repair 312
Polyhedrin 483
Stress-induced bacterial acidophilic repeat motif 8047
Acyl-CoA thioesterase 8117
Protein-arginine deiminase (PAD) 614
Protein of unknown function 522
Mitochondrial ribosomal protein S23 178
Endoribonuclease L-PSP 55642
Protein of unknown function (DUF1140) 330
Rec10 / Red1 44
Bacteriophage CI repressor helix-turn-helix domain 2428
Acetyltransferase (GNAT) domain 15191
Creatinase/Prolidase N-terminal domain 35158
Late embryogenesis abundant protein 18 74
BING4CT (NUC141) domain 783
SH3 domain-binding protein 5 (SH3BP5) 418
Domain of unknown function (DUF4072) 420
POTRA domain 8927
FANCI helical domain 2 277
CRISPR-associated protein 412
Ion channel regulatory protein UNC-93 1338
D-ala-D-ala dipeptidase 8286
Inositol 1 1165
Sec23-binding domain of Sec16 1391
Protein of unknown function (DUF3267) 9551
Herpesvirus UL37 tegument protein 113
Alpha/beta hydrolase family 71545
ThiC-associated domain 10393
Tropomodulin 847
DNA Fragmentation factor 45kDa 113
15-O-acetyltransferase Tri3 82
Retroviral aspartyl protease 178569
Domain of unknown function (DUF3980) 212
SAM domain (Sterile alpha motif) 7029
Domain of unknown function (DUF4270) 824
Transmembrane 219 219
Protein of unknown function (DUF2873) 79
Eukaryotic integral membrane protein (DUF1751) 832
GHMP kinases N terminal domain 76629
Domain of unknown function (DUF3480) 372
Spo0E like sporulation regulatory protein 2797
Domain of Unknown Function (DUF3856) 11
Pentaxin family 1700
Poxvirus A12 protein 98
Vacuole effluxer Atg22 like 5476
Methyl-coenzyme M reductase operon protein D 112
Domain of unknown function (DUF4608) 29
Bombesin-like peptide 157
Stannin unstructured linker 91
Probable N6-adenine methyltransferase 756
Protein of unknown function (DUF1668) 785
Taq polymerase 41
Transcription termination factor nusG 28769
WW-domain ligand protein 604
FAM194 protein 243
Gal4-like dimerisation domain 194
Transducer of regulated CREB activity 330
Plasmodium histidine-rich protein (HRPII/III) 539
Mitochondrial 28S ribosomal protein S31 232
Domain of unknown function (DUF4645) 29
Protein of unknown function DUF58 16190
Rickettsia outer membrane protein B 208
Nuclear receptor repeat 48
Clathrin 844
DNA replication factor Dna2 773
PPAK motif 89
Ion channel inhibitory toxin 335
Eukaryotic family of unknown function (DUF1754) 599
Natural killer cell receptor 2B4 66
Virulence determinant 20
Miro-like protein 3029
Uncharacterized protein conserved in bacteria (DUF2320) 1456
Domain of unknown function (DUF4189) 3805
Sec63 Brl domain 3306
Bul1 C terminus 344
Protein of unknown function (DUF3422) 790
Brain and reproductive organ-expressed protein (BRE) 250
Glycosyl hydrolase family 53 2021
RNA methyltransferase 22446
KDPG and KHG aldolase 18958
Remorin 161
Choline sulfatase enzyme C terminal 1230
Protein of unknown function (DUF3273) 209
Putative SAM-dependent RNA methyltransferase 582
Domain of unknown function (DUF1910) 509
Protein phosphatase 1 regulatory subunit 35 C-terminus 107
Protein of unknown function (DUF552) 11538
Proacrosin binding protein sp32 107
Putative carnitine deficiency-associated protein 322
Protein of unknown function (DUF2909) 1333
PCI domain 11127
Down syndrome cell adhesion molecule C terminal 99
Amnionless 184
Influenza C hemagglutinin stalk 177
7TM receptor with intracellular HD hydrolase 2738
Domain of unknown function (DUF4226) 4922
Protein of unknown function (DUF1227) 792
Domain of unknown function (DUF4470) 706
Selenoprotein P 18
Effector protein 477
AsmA family 16676
Helix-turn-helix domain 2011
Domain of unknown function (DUF1949) 15398
Follistatin/Osteonectin-like EGF domain 630
Uncharacterized conserved protein (DUF2181) 321
Surface antigen 4869
YueH-like protein 4367
Heavy-metal-associated domain 61989
Protein of unknown function (DUF826) 1836
Flagellar-associated PapD-like 673
Gill-associated viral 3C-like peptidase 13
Domain of unknown function (DUF4659) 139
XFP C-terminal domain 3157
Protein of unknown function (DUF1048) 1087
Bacterial regulatory proteins 263865
Interferon alpha/beta domain 1296
Protein of unknown function (DUF3194) 95
Potyviridae polyprotein 1613
White spot syndrome virus structural envelope protein VP 52
Glycosyltransferase like family 2 1646
CTP synthase N-terminus 22730
Putative zinc-finger 10862
Plant self-incompatibility response (SCRL) protein 269
Fructose-1-6-bisphosphatase 10405
HlyD family secretion protein 58501
UTP15 C terminal 725
SMI1 / KNR4 family (SUKH-1) 5261
Cardiac transcription factor regulator 213
Protein of unknown function (DUF3177) 166
Protein of unknown function (DUF3608) 693
RESP18 domain 170
Putative toxin 41 28
Tetrahydrodipicolinate succinyltransferase N-terminal 6837
Paf1 727
Male germ-cell putative homeodomain transcription factor 318
PD-(D/E)XK nuclease superfamily 40448
Vibrio cholerae sialidase 168
Metal-sensitive transcriptional repressor 31732
Low temperature viability protein 622
3-oxo-5-alpha-steroid 4-dehydrogenase 2796
BT1 family 2076
Speriolin N terminus 84
Human herpesvirus U15 protein 8
Allergen Fel d I-B chain 62
Helix-turn-helix domain 32254
TruB family pseudouridylate synthase (N terminal domain) 22775
Domain of unknown function (DUF3599) 131
Neutral trehalase Ca2+ binding domain 446
Hypothetical protein Yqai 114
TIR domain 6957
Uncharacterized protein conserved in bacteria (DUF2264) 2455
Alpha-amylase 23
Nin one binding (NOB1) Zn-ribbon like 790
Stf0 sulphotransferase 2118
Transcription factor zinc-finger 1413
SEN1 N terminal 418
Special lobe-specific silk protein SSP160 6
Protein of unknown function (DUF2709) 151
Cyclo-malto-dextrinase C-terminal domain 605
BNR/Asp-box repeat 2043
Domain of unknown function 373
Universal stress protein B (UspB) 4139
Endodeoxyribonuclease RusA 15192
Mitochondrial 28S ribosomal protein S32 217
Ste50p 47
Viral Beta C/D like family 32
Prosystemin 12
Domain of unknown function (DUF4632) 17
Testis-specific gene 13 protein 46
Cation transporting ATPase 32614
Domain of unknown function (DUF4074) 380
Family of unknown function (DUF577) 99
Flagellar protein FliT 5214
Tetratricopeptide repeat 22186
DNA polymerase III psi subunit 4415
ADP-specific Phosphofructokinase/Glucokinase conserved region 447
HAT (Half-A-TPR) repeat 693
Pleckstrin homology domain 837
AAA domain 8590
Domain of unknown function (DUF4596) 158
Protein of unknown function (DUF3131) 965
Bacteriophage Prd1 7
Domain of unknown function (DUF3409) 385
Bravo-like intracellular region 771
Protein of unknown function (DUF3542) 206
Intracellular growth locus C protein 47
Domain of unknown function (DUF1741) 499
Low molecular weight phosphotyrosine protein phosphatase 39173
Protein of unknown function (DUF1150) 784
S-phase genomic integrity recombination mediator 149
TRI9 protein 20
Protein of unknown function (DUF2680) 257
Domain of unknown function (DUF3284) 1666
TATA box-binding protein binding 232
Spore germination protein 4690
IMP dehydrogenase / GMP reductase domain 39324
Mediator complex subunit 13 N-terminal 506
Domain of unknown function (DUF1971) 6670
Putative glycoside hydrolase xylanase 1638
TnsA endonuclease N terminal 2698
Protein of unknown function (DUF2551) 57
Protein of unknown function (DUF1441) 3080
Smad anchor for receptor activation (SARA) 157
Staphylococcal nuclease homologue 18023
Serotonin (5-HT) neurotransmitter transporter 108
Type I phosphodiesterase / nucleotide pyrophosphatase 11710
Protein of unknown function (DUF805) 21243
Protein of unknown function (DUF2626) 504
CHASE3 domain 3470
Domain of unknown function (DUF333) 8981
Memo-like protein 1836
Pas factor saposin fold 126
Protein of unknown function (DUF2805) 596
Domain of unknown function (DUF3526) 432
Protein of unknown function (DUF2439) 571
Protein of unknown function (DUF1699) 90
Skp1 family 2393
Phage holin family 2 1148
Scaffold protein Ste5-Fus5 binding region 14
Uncharacterised conserved protein (DUF2366) 160
Protein of unknown function (DUF3450) 980
dsDNA Poxvirus 571
Ceroid-lipofuscinosis neuronal protein 6 136
Protein of unknown function (DUF2685) 76
Curtovirus V2 protein 36
WGR domain 6124
Flagellar hook-basal body complex protein FliE 9156
Major intrinsic protein 34117
Protein of unknown function (DUF1423) 464
mRNA (guanine-7-)methyltransferase (G-7-MTase) 798
C-terminus of AA_permease 1963
Type IV secretion system proteins 2198
E7 protein 1005
Sex determination protein N terminal 147
CrcB-like protein 28510
Plant specific eukaryotic initiation factor 4B 221
KAP family P-loop domain 3349
Domain of unknown function (DUF1792) 644
Syncollin 49
Fibronectin type I domain 430
TMEM151 family 286
Fibrillarin 1383
RNA polymerase III subunit RPC82 helix-turn-helix domain 631
CbiX 11331
DNA polymerase III 43647
FliG C-terminal domain 9655
DBP10CT (NUC160) domain 659
Enhancer of polycomb-like 2304
Small proline-rich 2 91
Protein of unknown function (DUF997) 4542
Udp N-acetylglucosamine O-acyltransferase; Domain 2 10459
Lantibiotic streptin immunity protein 540
Protein of unknown function (DUF1184) 49
Macrophage migration inhibitory factor (MIF) 1463
Protein of unknown function (DUF2892) 7146
Protein of unknown function (DUF2733) 35
Spore coat protein Z 752
Type III secretion protein (HpaP) 370
Signal recognition particle 9 kDa protein (SRP9) 670
Domain of unknown function (DUF1938) 20
RNA polymerase Rpb2 13688
hAT family C-terminal dimerisation region 7230
Amyloid A4 N-terminal heparin-binding 544
Protein of unknown function (DUF3352) 374
Suppressor of RNA silencing P21-like 256
YGGT family 18989
Protein of unknown function (DUF3942) 223
Coiled stalk of trimeric autotransporter adhesin 10277
E3 Ubiquitin ligase 850
Mitochondrial export protein Som1 228
Type IIB DNA topoisomerase 1239
Protein of unknown function 20978
Domain of unknown function (DUF3507) 139
Uroporphyrinogen decarboxylase (URO-D) 20873
C. elegans Sre G protein-coupled chemoreceptor 517
HAUS augmin-like complex subunit 2 208
Bacterial type III secretion protein (HrpB2) 373
Sulphur oxidation protein SoxZ 881
BmKX 14
Domain of unknown function (DUF4476) 634
Protein of unknown function (DUF1573) 2216
Bacteriophage replication protein O 3924
Protein of unknown function (DUF3677) 214
Beta-lactamase enzyme family 19507
Leucine operon leader peptide 465
PPR repeat 7869
Protein of unknown function (DUF2668) 103
Disulfide bond isomerase protein N-terminus 9323
Protein of unknown function (DUF2516) 2245
Hormone-sensitive lipase (HSL) N-terminus 246
Domain of unknown function (DUF1908) 565
Protein of unknown function (DUF3254) 95
Scavenger mRNA decapping enzyme C-term binding 3455
Outer membrane protein family (DUF1597) 1070
FYVE-type zinc finger 1297
Alanine racemase 32198
Nuclear transition protein 2 44
Conjugal transfer protein 5033
Phage capsid scaffolding protein (GPO) serine peptidase 4171
pORF2a truncated protein 69
Peptidase family C4 1618
Protein of unknown function (DUF1556) 3
Protein of unknown function (DUF1490) 5091
Acyl-CoA dehydrogenase 164347
1 1684
Erythrocyte membrane-associated giant protein antigen 332 27
Insulin-resistance promoting peptide in skeletal muscle 112
Synaptonemal complex protein 1 (SCP-1) 139
Vacuolar segregation subunit 7 294
Lactococcus bacteriophage repressor 75
Poxvirus C7/F8A protein 108
Uncharacterised protein family (UPF0164) 116
Salmonella surface presentation of antigen gene type M protein 1566
Parvovirus non-structural protein NS1 1923
Tospovirus nucleocapsid protein 1416
Conserved mid region of cactin 686
Nudix N-terminal 2412
Protein of unknown function (DUF3121) 2354
CpeS-like protein 505
Falstatin 27
Arsenical resistance operon trans-acting repressor ArsD 2032
Domain of unknown function (DUF2020) 121
PCAF (P300/CBP-associated factor) N-terminal domain 318
Phospholipase D Active site motif 6247
zinc-RING finger domain 1583
Plasmid stability protein 2977
FeoC like transcriptional regulator 4688
YEATS family 1850
Putative cell wall binding repeat 11181
Thioredoxin 93607
DEC-1 protein 35
Protein of unknown function (DUF1221) 93
4Fe-4S dicluster domain 65631
Domain of unknown function (DUF4557) 89
Bacterial membrane-spanning protein N-terminus 364
NADH pyrophosphatase zinc ribbon domain 10513
WWamide peptide 3
Fas apoptotic inhibitory molecule (FAIM1) 236
Protein of unknown function (DUF3115) 341
Domain of unknown function (DUF4598) 349
Bacteriophage lambda integrase 5022
Negative regulator of p53/TP53 168
Sporulation protein YtrH 575
Protein of unknown function (DUF1638) 485
Domain of unknown function (DUF4361) 146
PWWP domain 4728
Mastadenovirus E4 ORF3 protein 137
Domain of unknown function (DUF4349) 1624
Monomeric isocitrate dehydrogenase 5462
RRM in Demeter 224
impB/mucB/samB family 45799
Domain of unknown function (DUF4612) 167
Predicted aminopeptidase (DUF2265) 887
N-terminal domain of (some) glycogen debranching enzymes 969
S-antigen protein 66
Domain of unknown function (DUF4292) 668
Ribonuclease B OB domain 20962
RDD family 20790
Domain of unknown function (DUF718) 6782
Domain of unknown function (DUF4261) 1243
Integral membrane protein DUF95 7797
Biofilm development protein YmgB/AriR 5522
K1 glycoprotein 969
Leukotriene A4 hydrolase 1360
Baculovirus gp64 envelope glycoprotein family 62
Protein of unknown function (DUF2839) 262
Modulator of Rho-dependent transcription termination (ROF) 4547
YpjP-like protein 440
Herpesvirus Glycoprotein B 1658
Protein of unknown function (DUF4127) 373
Allexivirus 40kDa protein 38
Ectoine synthase 1281
Peptidase family M49 1396
Ribonuclease III domain 11132
C-terminal duplication domain of Friend of PRMT1 926
Glycoprotein UL132 98
Glycolipid 2-alpha-mannosyltransferase 1736
PAR1 protein 171
Meiotic recombination protein rec114 44
Protein of unknown function (DUF3820) 6631
Cell division inhibitor SulA 4323
Rad51 4421
Domain of unknown function (DUF4268) 591
Domain of unknown function (DUF4304) 454
S-adenosylmethionine-dependent methyltransferase 22713
Protein of unknown function (DUF4526) 84
Glutamine synthetase type III N terminal 1803
Mac 1 378
PyrBI operon leader peptide 1182
GTF2I-like repeat 369
Domain of unknown function (DUF1926) 203
Protein of unknown function (DUF1052) 780
DNA polymerase III polC-type N-terminus II 7444
Cupredoxin-like domain 7772
Protein of unknown function (DUF3760) 63
Domain of unknown function (DUF1934) 7866
Uncharacterised protein family (UPF0041) 1786
RSC complex 42
Gag protein p6 27778
Mre11 DNA-binding presumed domain 870
Pterin binding enzyme 38582
Domain of Unknown Function (DUF1547) 234
Initiation factor eIF2 gamma 1305
Retroviral M domain 238
Ribosomal protein L6 637
Molybdopterin oxidoreductase Fe4S4 domain 57304
Aurein-like antibiotic peptide 30
2C endopeptidase (C24) cysteine protease family 162
NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 36894
YwpF-like protein 4443
Protein of unknown function (DUF3392) 761
Quinohemoprotein amine dehydrogenase 150
Domain of unknown function (DUF4111) 6983
Protein of unknown function (DUF4238) 1853
Minimal binding motif of Hap4 for binding to Hap2/3/5 430
Vaculolar membrane protein 769
NADH dehydrogenase subunit 2 C-terminus 39181
Protein of unknown function (DUF1421) 237
Sigma-54 factor 11894
Gcd10p family 791
Protein of unknown function (DUF3104) 92
CBP4 337
Serpentine type 7TM GPCR chemoreceptor Str 1431
Bacterial mobilisation protein (MobC) 5324
Neuronal voltage-dependent calcium channel alpha 2acd 258
DNA polymerase III subunits gamma and tau domain III 15911
Ubiquinol-cytochrome C reductase hinge protein 863
Predicted Permease Membrane Region 11787
Chaperone for wingless signalling and trafficking of LDL receptor 292
Protein of unknown function (DUF3995) 672
Hepsin 80
Nuclear RNA-splicing-associated protein 179
Conserved TM helix 8247
Protein of unknown function (DUF2840) 612
RNA binding 636
Protein of unknown function (DUF613) 7
Frigida-like protein 1111
Uncharacterised protein family (UPF0154) 7086
Guanylyl transferase CofC like 2317
GDA1/CD39 (nucleoside phosphatase) family 3047
Transmembrane protein 231 241
phosphotransferase system 90030
Beta2-adaptin appendage 842
EBP50 241
Transposase family tnp2 1709
Adenylate cyclase 5162
Domain of unknown function (DUF1902) 193
Nepovirus coat protein 507
LUC7 N_terminus 1386
Helix-turn-helix of DDE superfamily endonuclease 3435
Protein of unknown function (DUF1192) 607
HAD superfamily 11720
Protein of unknown function (DUF673) 94
ATP-NAD kinase 25275
mbt repeat 1399
NPL4 family 682
NAD binding domain of 6-phosphogluconate dehydrogenase 61470
Borrelia lipoprotein 2340
Restriction endonuclease BsobI 61
Restriction endonuclease HincII 18
Phage related protein 258
Eukaryotic-type carbonic anhydrase 7287
Stage II sporulation protein E (SpoIIE) 25334
Alpha-acetolactate decarboxylase 12043
Protein of unknown function (DUF3017) 3884
Protein of unknown function (DUF3080) 491
Domain of unknown function (DUF4464) 274
Protein kinase C terminal domain 7030
Domain of Unknown Function (DUF349) 3525
Protein of unknown function (DUF3884) 975
Tetrahydromethanopterin S-methyltransferase 76
RNA polymerase Rpb1 31000
Thrombin light chain 145
Rap/ran-GAP 2367
Ferrous iron transport protein B 17035
Cellulose binding domain 989
Probable lipoprotein LpqN 5492
Micro-tubular organiser Mto1 C-term Mto2-binding region 218
Phage head completion protein (GPL) 4024
Adenovirus E3 region protein CR2 218
Bacteriophage Mu transposase 309
Protein of unknown function (DUF3718) 316
Phage Conserved Open Reading Frame 51 9212
Beige/BEACH domain 2853
Domain of unknown function (DUF4606) 89
Nerve growth factor family 5813
Adenovirus E1B protein N-terminus 216
DALR domain 20624
Protein of unknown function (DUF3934) 262
Schizosaccharomyces pombe repeat of unknown function (DUF963) 14
Protein of unknown function (DUF 659) 1399
Kinetochore component 85
CobW/HypB/UreG 59813
Protein of unknown function (DUF2686) 2710
Plant protein of unknown function (DUF639) 311
Acetamidase/Formamidase family 3769
Hedgehog signalling target 145
Protein of unknown function (DUF459) 614
Cell cycle protein 44748
Protein of unknown function (DUF507) 619
Protein of unknown function (DUF2868) 1006
Herpesvirus alkaline exonuclease 331
ATPase MipZ 1687
CoA-ligase 44358
Methyladenine glycosylase 19543
Stannin transmembrane 92
Protein of unknown function (DUF2808) 407
Carlavirus endopeptidase 183
CCR4-Not complex component 961
Secretion monitor precursor protein (SecM) 3846
Glycosyl transferase family 21 2045
Metallopeptidase toxin 2 18
Ran-interacting Mog1 protein 634
Domain of unknown function (DUF2610) 104
Protein of unknown function (DUF1682) 763
Helix-turn-helix domain 20233
Lipid-A-disaccharide synthetase 10302
Protein of unknown function (DUF2420) 304
She9 / Mdm33 family 367
A-kinase anchor protein 110 kDa (AKAP 110) 231
Bacteriophage Gp15 protein 544
Anthrax toxin lethal factor 35
SBP domain 1429
Transposase 3327
HMGL-like 60189
Bacterial ABC transporter protein EcsB 7603
Associated with HOX 785
Protein of unknown function (DUF688) 495
Protein of unknown function (DUF3069) 359
Fungal immunomodulatory protein Fve 24
NikR C terminal nickel binding domain 5727
DNA mismatch repair protein 20072
Protein of unknown function (DUF1378) 1163
Protein of unknown function (DUF2590) 469
Galactose binding lectin domain 2425
Susceptibility to monomelic amyotrophy 98
Small Multidrug Resistance protein 34115
Flagellar regulatory protein FleQ 1246
YopE 95
ATP-sulfurylase 2940
Ribosomal protein S21 19139
Protein of unknown function (DUF3239) 178
Colicin D 263
Type III secretion needle MxiH like 6867
Golgi phosphoprotein 3 (GPP34) 1428
Spt5 transcription elongation factor 645
Syntaxin 6 1026
Temperature dependent protein affecting M2 dsRNA replication 540
Mannitol dehydrogenase Rossmann domain 29908
HEAT repeat 3855
Eukaryotic elongation factor 1 beta central acidic region 1004
Glutamine amidotransferases class-II 10136
Anaphase-promoting complex APC subunit 1 364
Protein of unknown function (DUF4058) 144
Domain of unknown function (DUF4542) 70
Glycosyl hydrolase like GH101 6362
Domain of unknown function (DUF4251) 759
Arterivirus glycoprotein 408
DNA-directed RNA polymerase I subunit RPA34.5 394
Ocular albinism type 1 protein 161
Ribosomal Proteins L2 25501
ATP synthase (F/14-kDa) subunit 3221
Protein of unknown function 2066
Domain of unknown function (DUF4211) 585
Sarcoglycan complex subunit protein 608
Protein of unknown function (DUF3151) 2345
O-methyltransferase 21502
Ustilago B locus mating-type protein 50
Protein of unknown function (DUF3293) 603
Caf1 Capsule antigen 91
MASE2 domain 3915
Domain of unknown function (DUF1906) 3139
Lamina-associated polypeptide 2 alpha 45
Protein of unknown function (DUF3141) 592
TadE-like protein 5720
Protein of unknown function (DUF3419) 690
Primase C terminal 2 (PriCT-2) 1198
Immunity protein 47 455
Pox virus D2 protein 66
Domain of unknown function (DUF4468) with TBP-like fold 816
CotH protein 2416
Coiled-coil domain-containing protein 66 222
NLI interacting factor-like phosphatase 6474
FERM N-terminal domain 5298
TcdA/TcdB pore forming domain 580
Cell morphogenesis central region 790
Bunyavirus non-structural protein NS-s 301
Vestigial/Tondu family 352
Protein of unknown function (DUF3319) 351
GTP-binding protein TrmE N-terminus 19065
Mitochondrial small ribosomal subunit Rsm22 1430
Protein of unknown function (DUF2848) 500
Poxvirus RNA polymerase 22 kDa subunit 61
Potassium channel Kv1.4 tandem inactivation domain 81
Putative ATP-dependent Lon protease 1003
CheY binding 3882
T4 RNase H 96
Autophagy protein Apg5 811
Exonuclease VII 20822
C-terminus of bacterial fibrinogen-binding adhesin 29446
COG (conserved oligomeric Golgi) complex component 747
MDM2-binding 113
Competence protein CoiA-like family 8156
Pertussis toxin S5 subunit 86
PI-PfuI Endonuclease subdomain 5
D-alanyl-D-alanine carboxypeptidase 44967
Protein of unknown function (DUF2493) 1000
Metallopeptidase family M24 86248
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 25514
NADH:ubiquinone oxidoreductase 400
Protein of unknown function (DUF3219) 113
Protein of unknown function (DUF3624) 355
APC 15 residue motif 185
Nucleoside 2-deoxyribosyltransferase 3816
Protein of unknown function (DUF1218) 1084
Protein of unknown function (DUF1749) 556
Ion transport protein 26775
Uncharacterized protein conserved in bacteria (DUF2321) 200
Protein of unknown function (DUF2603) 490
Nitrate reductase cytochrome c-type subunit (NapB) 4613
Olfactomedin-like domain 1801
Histidine kinase- 31581
Toxin SpoIISA 346
Invasion gene expression up-regulator 5793
Ponericin 5
Arginine repressor 25796
Domain of unknown function (DUF3382) 6104
Selenium binding protein 14
Exotoxin A 295
Putative toxin 51 14
Domain of unknown function (DUF3327) 5861
Protein of unknown function (DUF1229) 179
Firmicute fructose-1 6795
Protein of unknown function (DUF938) 1201
Putative serine esterase (DUF676) 2867
N-terminal domain of DPF2/REQ. 452
Biotin and Thiamin Synthesis associated domain 24943
Class II vitamin B12-dependent ribonucleotide reductase 1304
Putative phosphatase (DUF442) 3622
Borrelia ORF-A 854
Domain of unknown function (DUF3372) 1172
SpoVR like protein 6437
Protein of unknown function (DUF2811) 246
Domain of unknown function (DUF4078) 439
ApaLI-like restriction endonuclease 519
Protein kinase domain 269477
D1 dopamine receptor-interacting protein (calcyon) 277
Domain of unknown function (DUF4492) 581
Protein of unknown function (DUF1182) 22
Indigoidine synthase A like protein 8030
Alpha-L-arabinofuranosidase B (ABFB) 745
TCP-1/cpn60 chaperonin family 53893
G2F domain 503
Cation transporter/ATPase 32467
Protein of unknown function (DUF725) 227
Domain of unknown function (DUF4281) 377
NifT/FixU protein 397
KIF-1 binding protein C terminal 346
Poxvirus G7-like 80
Protein of unknown function (DUF3160) 309
Protein of unknown function (DUF768) 396
PDZ domain (Also known as DHR or GLGF) 49506
DNA directed RNA polymerase 902
Protein of unknown function (DUF3587) 131
Copper binding periplasmic protein CusF 6217
Allophanate hydrolase subunit 2 22030
Protein of unknown function (DUF2693) 195
SelR domain 23489
Protein of unknown function (DUF1199) 6
Protein of unknown function (DUF1440) 7327
Domain of unknown function (DUF3846) 519
BMP-2-inducible protein kinase C-terminus 190
beta-acetyl hexosaminidase like 1340
Ham1 family 22728
Class II MHC-associated invariant chain trimerisation domain 145
Protein of unknown function 1131
Hepatitis C virus NS3 protease 17877
L27_2 202
HTH-like domain 48549
UcrQ family 575
MobA/MobL family 4663
Aurora kinase A and ninein interacting protein 40
Ribosomal protein L33 31376
Putative viral replication protein 2258
Protein of unknown function (DUF1669) 782
Pyridoxamine 5'-phosphate oxidase 760
3-dehydroquinate synthase (EC 4.6.1.3) 527
Hamartin protein 463
Domain of unknown function (DUF4607) 26
Creatinine amidohydrolase 5802
Arenavirus glycoprotein 683
Yersinia pseudotuberculosis mitogen 5
XS domain 577
Photosystem II complex subunit Ycf12 473
Retrograde transport protein Dsl1 C terminal 139
SAM like domain present in kinase suppressor RAS 1 255
Domain of unknown function (DUF756) 3449
Domain of unknown function (DUF1877) 2849
Protein of unknown function (DUF1769) 372
ELK domain 2069
Conjugative transposon protein TraO 902
4-alpha-glucanotransferase 12057
N-acetylglucosaminyltransferase II (MGAT2) 346
AIR carboxylase 22954
Coiled-coil receptor-binding R-domain of colicin E2 335
Membrane magnesium transporter 662
Lantibiotic dehydratase 1821
Herpesvirus glycoprotein M 236
Fimbrial adhesin F17-AG 29
DNA-binding nuclear phosphoprotein p8 212
Phosphoribosyl transferase domain 144356
Protein of unknown function (DUF_B2219) 546
Chlorophyllase enzyme 128
Toxin with a H 35
Tetracycline resistance leader peptide 22
Tumour protein p53-inducible protein 11 176
HupE / UreJ protein 1255
Elongation factor SelB 5291
Poly(ADP-ribose) polymerase catalytic domain 4130
Fibronectin type II domain 1643
Mediator complex subunit 25 PTOV activation and synapsin 2 219
DMAP1-binding Domain 770
Cation channel sperm-associated protein subunit delta 125
Patched family 5427
PPR repeat 27074
Protein of unknown function (DUF2999) 362
Gamma interferon inducible lysosomal thiol reductase (GILT) 1115
Permease for cytosine/purines 22715
Protein of unknown function (DUF1679) 328
Ciliary BBSome complex subunit 1 239
Protein of unknown function (DUF2552) 339
Bacteriophage T4 beta-glucosyltransferase 12
Protein of unknown function (DUF1634) 1090
Luciferase helical bundle domain 34
ATP-binding sugar transporter from pro-phage 2075
Nucleocapsid protein N 51
Periplasmic binding protein domain 62501
Colicin Ia 340
Hemimethylated DNA-binding protein YccV like 5246
Tir chaperone protein (CesT) family 6779
Big defensin 46
Aurora-A binding 106
Protein of unknown function (DUF1376) 1957
Domain of unknown function (DUF1931) 99
Ubiquitin-activating enzyme e1 C-terminal domain 1222
Mak10 subunit 728
NADH dehydrogenase I 46
Plant protein of unknown function (DUF641) 355
RNase_H superfamily 4599
MlrC C-terminus 2255
Methyltransferase domain 38496
Reticulon 2741
Protein of unknown function (DUF3788) 945
LIN37 271
Protein of unknown function (DUF1113) 3402
DNA circularisation protein N-terminus 1786
Domain of unknown function (DUF1923) 14
PepSY-associated TM helix 16428
RecO N terminal 527
Predicted coiled-coil protein (DUF2205) 512
SeqA protein 4511
ATP-dependent DNA helicase recG C-terminal 5396
Protein of unknown function (DUF1466) 135
Interferon-regulatory factor 3 1049
Viral capsid protein 91 N-terminal 108
Protein of unknown function (DUF1697) 4344
chorismate binding enzyme 61307
Tim10/DDP family zinc finger 3266
Interleukin-4 receptor alpha chain 127
RNA replicase 318
Nucleolar complex-associated protein 710
Stigma-specific protein 434
Uncharacterized protein conserved in bacteria (DUF2334) 1719
Geminivirus C4 protein 2806
Protein of unknown function (DUF1598) 41
Nucleopolyhedrovirus protein of unknown function (DUF919) 175
Bacterial transcriptional repressor 2867
VWA domain containing CoxE-like protein 14584
Protein of unknown function (DUF4448) 358
Whirly transcription factor 217
Iron-Sulfur binding protein C terminal 295
Reovirus outer capsid protein 253
Nodulation protein NolV 247
Takusan 577
6-O-methylguanine DNA methyltransferase 39756
Domain of unknown function (DUF771) 4186
Family of unknown function 190
Transferrin receptor-like dimerisation domain 1878
ZPR1 zinc-finger domain 1059
Protein of unknown function (DUF455) 2250
Cortexin of kidney 223
Imelysin 11977
Monooxygenase subunit B protein 191
Mitochondrial ATP synthase g subunit 776
Protein of unknown function (DUF2764) 584
Hemerythrin HHE cation binding domain 26036
Putative excisionase (DUF1233) 3195
SAM dependent carboxyl methyltransferase 1717
CreA protein 6005
Protein of unknown function (DUF3124) 203
Shikimate dehydrogenase substrate binding domain 31531
Domain of unknown function (DUF374) 1885
Domain of unknown function (DUF3546) 682
Domain of unknown function (DUF4371) 2578
Immunity protein 42 195
Protein of unknown function (DUF2441) 268
Protein of unknown function (DUF1040) 4361
ATP-utilising chromatin assembly and remodelling N-terminal 765
Protein of unknown function (DUF2616) 58
Component of IIS longevity pathway SMK-1 1039
Microtubule-binding stalk of dynein motor 4588
Uncharacterized BCR 9274
Rab15 effector 57
Poxvirus D5 protein-like 5583
Domain of unknown function (DUF4306) 321
Glutathione S-transferase 19490
Coiled-coil domain-containing protein 14 134
UPF0731 family 61
Domain of unknown function (DUF1956) 5368
Methyltransferase domain 532
P22 tail accessory factor 688
Dissimilatory sulfite reductase D (DsrD) 79
Bucentaur or craniofacial development 706
Bacillus thuringiensis toxin 122
Bacterial PH domain 2507
Domain of unknown function (DUF2520) 4925
Tektin family 1470
TMP repeat 474
Group XII secretory phospholipase A2 precursor (PLA2G12) 364
Protein of unknown function (DUF1590) 5
Pilus assembly protein 2672
U5-snRNA binding site 2 of PrP8 825
MT-A70 3311
PaaX-like protein 5271
Cytochrome b(C-terminal)/b6/petD 105337
Protein of unknown function (DUF1629) 177
HAD-hyrolase-like 38901
Stress responsive A/B Barrel Domain 4253
Staphylococcal AgrD protein 4255
Protein of unknown function 383
TraB family 7970
Protein of unknown function (DUF3592) 3144
Aft1 HRA domain 261
Human herpesvirus 6 immediate early protein 40
Hexameric tyrosine-coordinated heme protein (HTHP) 99
Protein of unknown function (DUF3986) 538
Uncharacterised conserved protein (DUF2228) 263
Putative zinc binding domain 1226
Mad3/BUB1 homology region 1 1003
Influenza Matrix protein (M1) C-terminal domain 41413
Thymidine kinase 14702
Domain of unknown function (DUF4234) 758
Protein of unknown function (DUF3103) 386
Domain of unknown function (DUF1933) 17
DNA polymerase family A 28763
Peroxidase 19815
Gon7 family 268
NolX protein 119
TMEM240 family 92
Intimin C-type lectin domain 1038
Replication protein 10093
Acyl-ACP thioesterase 7569
Relaxase/Mobilisation nuclease domain 9578
Taurine catabolism dioxygenase TauD 23204
L-2-amino-thiazoline-4-carboxylic acid hydrolase 1311
HPr Serine kinase C-terminal domain 10401
Pyridine nucleotide-disulphide oxidoreductase 268401
Putative toxin 40 8
Glycosyltransferase WbsX 961
Protein of unknown function (DUF3283) 360
GTPase binding 282
Bacteriophage CII protein 2813
Acyl transferase 86
DinB family 4590
Putative toxin 49 86
Transketolase 78441
36-mer N-terminal peptide of the N protein (N36) 295
Protein of unknown function (DUF1266) 8106
Coronavirus NSP13 854
Domain of unknown function (DUF4097) 8773
DNA polymerase family B viral insert 130
Protein of unknown function (DUF3292) 272
Domain of unknown function (DUF3576) 344
Domain of unknown function (DUF4309) 454
Protein of unknown function (DUF4497) 135
Vitamin D binding protein 78
Protein of unknown function (DUF2875) 708
Protein of unknown function (DUF3196) 96
S1 domain 9100
Small acidic protein family 655
Zeta toxin 5902
Protein of unknown function (DUF1163) 46
Ta0938 36
IBR domain 6603
TrwC relaxase 3313
Reversibly glycosylated polypeptide 445
Protein of unknown function (DUF3531) 334
Protein of unknown function (DUF2663) 177
Baculoviridae late expression factor 5 C-terminal domain 94
Salmonella repeat of unknown function (DUF823) 2463
Capsule assembly protein Wzi 2087
Flavin containing amine oxidoreductase 37095
Late expression factor 8 (LEF-8) 425
2OG-Fe dioxygenase 1358
Protein of unknown function (DUF3272) 849
Mitochondrial 39-S ribosomal protein L47 (MRP-L47) 742
DSS1/SEM1 family 690
CEP76 C2 domain 183
BofC C-terminal domain 475
Protein of unknown function (DUF3012) 371
HNH endonuclease 2594
Domain of unknown function (DUF4258) 1170
Est1 DNA/RNA binding domain 1727
RNA polymerase I-specific transcription-initiation factor 308
PepSY-associated TM helix 13184
MIF4G like 788
PINIT domain 1012
Domain of unknown function (DUF4275) 291
X-Pro dipeptidyl-peptidase (S15 family) 16205
TMEM187 protein family 62
Metallothionein 588
Polyphosphate kinase middle domain 14801
Ubiquitin interaction motif 2067
Plant pleckstrin homology-like region 407
Protein of unknown function (DUF3978) 225
Tsp45I type II restriction enzyme 121
Porphobilinogen deaminase 18888
CotJB protein 1499
Domain of unknown function (DUF4353) 815
N-formylglutamate amidohydrolase 5706
Domain of unknown function DUF1829 8468
P-loop containing region of AAA domain 2981
Domain of unknown function (DUF1854) 337
Toxin Fst 139
Galactose mutarotase-like 9634
4-alpha-L-fucosyltransferase glycosyl transferase group 56 4107
S1-like 317
Mitochondrial ribosomal protein S25 343
Protein of unknown function (DUF3931) 219
Domain of unknown function (DUF4631) 75
Haemagluttinin repeat 4898
Erythrovirus X protein 26
GLTT repeat (6 copies) 1890
Domain of unknown function (DUF4605) 156
WhiA N-terminal LAGLIDADG-like domain 10500
YcgL domain 5969
Domain of unknown function (DUF4335) 267
Polymer-forming cytoskeletal 6706
GTP cyclohydrolase I 16834
Protein of unknown function (DUF1482) 6890
Uncharacterised protein family (UPF0104) 24209
c-SKI Smad4 binding domain 537
Uncharacterized protein 43
Spindle pole body component Spc42p 51
Rotavirus major capsid protein VP6 2342
Haemadin 2
Putative adipose-regulatory protein (Seipin) 738
Predicted integral membrane protein (DUF2269) 1495
Keratin 732
Shoulder domain 252
Adenovirus minor core protein PV 199
Protein of unknown function (DUF1207) 217
Orbivirus outer capsid protein VP2 696
Cypovirus polyhedrin protein 14
LNS2 (Lipin/Ned1/Smp2) 1650
Protein of unknown function (DUF3975) 218
Domain of unknown function 201
Formate--tetrahydrofolate ligase 14827
Ribosomal L18 C-terminal region 1334
ERK and JNK pathways 187
Domain of unknown function (DUF3536) 233
SCL-interrupting locus protein N-terminus 171
Nuclear transport factor 2 (NTF2) domain 6863
Bacterial protein of unknown function (DUF916) 4823
Dihydrofolate reductase 24221
Bcr-Abl oncoprotein oligomerisation domain 118
STOP protein 500
Protein of unknown function (DUF1285) 2267
Domain of unknown function (DUF1925) 155
Rap1 99
DNA polymerase III 4705
Domain of unknown function 33
Domain of unknown function (DUF932) 9982
Domain of unknown function (DUF3870) 538
Protein of unknown function (DUF3849) 223
Telomerase reverse transcriptase TEN domain 2
Mis6 379
Protein of unknown function (DUF2624) 425
Ubiquitin-like autophagy protein Apg12 660
Putative zinc finger motif 705
Nitrous oxide-stimulated promoter 4482
Protein of unknown function (DUF1155) 5
Myc amino-terminal region 2264
Phage protein 4620
Plasmid recombination enzyme 5693
TolB amino-terminal domain 8105
X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 15464
AP2 domain 14673
Brf1-like TBP-binding domain 824
Ribosomal S3Ae family 1809
EspG protein 647
Protein of unknown function (DUF4125) 306
Ras-mediated vulval-induction antagonist 94
Nuclear transition protein 1 49
Inositol phospholipid synthesis and fat-storage-inducing TM 724
Pre-T-cell antigen receptor 37
Mu B transposition protein 454
Lamina-associated polypeptide 1C (LAP1C) 272
Protein of unknown function (DUF3429) 964
Protein of unknown function 947
Minor tail protein T 5172
Ty3 transposon peptidase 26
CBS domain 191104
Uncharacterised protein family (UPF0128) 28
CRS1 / YhbY (CRM) domain 16051
YqzL-like protein 655
PQ loop repeat 5710
Mycoplasma haemagglutinin 452
SpoVG 6219
Borrelia burgdorferi BBR25 lipoprotein 132
Chlorophyllase 157
PTS system mannose/fructose/sorbose family IID component 26442
Haemolytic domain 16311
Insulin-like growth factor binding protein 1739
Domain of unknown function (DUF4174) 951
Melanoma associated antigen family N terminal 696
Formiminotransferase-cyclodeaminase 2041
Protein of unknown function (DUF1265) 19
TMEM125 protein family 105
NgoMIV restriction enzyme 110
Domain of unknown function (DUF3459) 14190
Phosphate-starvation-inducible E 8763
DNA polymerase family B exonuclease domain 112
Paramecium surface antigen domain 163
Gas vesicle protein G 288
Coleoptericin 16
YtxC-like family 962
Uncharacterised nucleotidyltransferase 1883
Phospholipase A2 inhibitor 154
RNA polymerase Rpb2 41861
Translocated intimin receptor (Tir) intimin-binding domain 628
Protein of unknown function (DUF674) 730
Cysteine-rich TM module stress tolerance 703
Domain of unknown function (DUF4307) 2354
Bacillus PapR protein 242
FAD synthetase 21161
N2227-like protein 1087
BURP domain 845
Protein of unknown function (DUF3218) 103
TAFII55 protein conserved region 896
Serum albumin family 487
Protein of unknown function (DUF1601) 48
Protein of unknown function C-terminus (DUF2448) 126
4Fe-4S binding domain 26132
PAP2 superfamily 1935
Mating factor alpha precursor N-terminus 114
SH3 domain of SH3b2 type 1581
Protein of unknown function (DUF2790) 2181
6 20430
Bacteriophage 1.1 Protein 51
YlzJ-like protein 567
DUSP domain 1697
Protein of unknown function (DUF2774) 59
Protein of unknown function (DUF2533) 372
7kD viral coat protein 508
Mitochondrial glycoprotein 1185
Seadornavirus Vp10 13
SRS domain 1352
Archaebacterial flagellin 778
arg-2/CPA1 leader peptide 40
Queuosine biosynthesis protein 19558
PET122 48
Retinal pigment epithelial membrane protein 7745
MoeA C-terminal region (domain IV) 21335
Helix-hairpin-helix containing domain 8934
Alb1 362
Bax inhibitor 1 like 3869
Protein of unknown function (DUF2712) 95
PFU (PLAA family ubiquitin binding) 824
Phosphoenolpyruvate carboxylase 229
WSK motif 163
Enterobacterial virulence protein IpgD 1033
Transcription factor TFIID (or TATA-binding protein 2492
Domain of Unknown Function (DUF350) 6945
Protein of unknown function (DUF3092) 86
Domain of unknown function (DUF4530) 37
Surface presentation of antigens protein 1386
Transcription factor/nuclear export subunit protein 2 882
Alpha-L-arabinofuranosidase C-terminus 3820
Family of unknown function (DUF572) 1519
Hairy Orange 1685